Constitutive Signaling by Overexpressed ERBB2

instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9634285)

Wikidata entity: Q100166259



P2860 cites work ... Q54791338 (???) ???
P2888 exact match Url Reactome | Constitutive Signaling by Overexpressed ERBB2 ???
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P527 has part(s) ... Q100152330 (ERBB2 homodimerization) ERBB2 homodimerization
P527 has part(s) ... Q100152331 (Trans-autophosphorylation of ERBB2 homodimer) Trans-autophosphorylation of ERBB2 homodimer
P527 has part(s) ... Q100152333 (SHC1 binds phosphorylated ERBB2 homodimer) SHC1 binds phosphorylated ERBB2 homodimer
P527 has part(s) ... Q100152334 (ERBB2 homodimer phosphorylates SHC1) ERBB2 homodimer phosphorylates SHC1
P527 has part(s) ... Q100152335 (Recruitment of GRB2:SOS1 to p-SHC1 in complex with phosphorylated ERBB2 homodimer) Recruitment of GRB2:SOS1 to p-SHC1 in complex with phosphorylated ERBB2 homodimer
P527 has part(s) ... Q100152336 (RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and ERBB2 homodimer:p-SHC1) RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and ERBB2 homodimer:p-SHC1
P527 has part(s) ... Q100152338 (ERBB2 binds trastuzumab) ERBB2 binds trastuzumab
P527 has part(s) ... Q100152341 (ERBB2 binds TKIs) ERBB2 binds TKIs
P31 instance of ... Q4915012 (biological pathway) biological pathway
P361 part of ... Q100166278 (Signaling by ERBB2 in Cancer) Signaling by ERBB2 in Cancer

External Ids
P3937Reactome IDR-HSA-9634285

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log id: 5409054