Signaling by ERBB2 TMD/JMD mutants

instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9665686)

Wikidata entity: Q100166275



P2860 cites work ... Q27851987 (???) ???
P2860 cites work ... Q34028470 (???) ???
P2860 cites work ... Q93198405 (???) ???
P2888 exact match Url None ???
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P527 has part(s) ... Q100152407 (ERBB2 TMD/JMD mutants hetrodimerize) ERBB2 TMD/JMD mutants hetrodimerize
P527 has part(s) ... Q100152408 (ERBB2 TMD/JMD heterodimers trans-autophosphorylate) ERBB2 TMD/JMD heterodimers trans-autophosphorylate
P527 has part(s) ... Q100152409 (Phosphorylated ERBB2 TMD/JMD heterodimers bind SHC1) Phosphorylated ERBB2 TMD/JMD heterodimers bind SHC1
P527 has part(s) ... Q100152410 (Phosphorylated heterodimers of ERBB2 TMD/JMD mutants phosphorylate SHC1) Phosphorylated heterodimers of ERBB2 TMD/JMD mutants phosphorylate SHC1
P527 has part(s) ... Q100152411 (Phosphorylated heterodimers of ERBB2 TMD/JMD mutants recruit GRB2:SOS1 through SHC1) Phosphorylated heterodimers of ERBB2 TMD/JMD mutants recruit GRB2:SOS1 through SHC1
P527 has part(s) ... Q100152412 (RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants) RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants
P527 has part(s) ... Q100152413 (Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR bind GRB2:SOS1) Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR bind GRB2:SOS1
P527 has part(s) ... Q100152414 (RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR) RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR
P527 has part(s) ... Q100152415 (Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR bind PLCG1) Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR bind PLCG1
P527 has part(s) ... Q100152416 (Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR phosphorylate PLCG1) Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR phosphorylate PLCG1
P527 has part(s) ... Q100152418 (ERBB2 TMD/JMD mutants bind TKIs) ERBB2 TMD/JMD mutants bind TKIs
P527 has part(s) ... Q100152420 (ERBB2 TMD/JMD mutants bind trastuzumab) ERBB2 TMD/JMD mutants bind trastuzumab
P527 has part(s) ... Q100152421 (ERBB2 TMD/JMD mutants bind pertuzumab) ERBB2 TMD/JMD mutants bind pertuzumab
P31 instance of ... Q4915012 (biological pathway) biological pathway
P361 part of ... Q100166278 (Signaling by ERBB2 in Cancer) Signaling by ERBB2 in Cancer

External Ids
P3937Reactome IDR-HSA-9665686

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log id: 5409166