9-cis-UAB30, a novel rexinoid agonist, decreases tumorigenicity and cancer cell stemness of human neuroblastoma patient-derived xenografts

scientific article published on 30 September 2020

9-cis-UAB30, a novel rexinoid agonist, decreases tumorigenicity and cancer cell stemness of human neuroblastoma patient-derived xenografts is …
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scholarly articleQ13442814

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P356DOI10.1016/J.TRANON.2020.100893
P932PMC publication ID7530346
P698PubMed publication ID33010553

P2093author name stringKarina J Yoon
Elizabeth A Beierle
Jerry E Stewart
Laura L Stafman
Laura V Bownes
Adele P Williams
Raoud Marayati
Colin H Quinn
Jamie M Aye
Venkatram Atigadda
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Human GAP-43 Gene Expression: Multiple Start Sites for Initiation of Transcription in Differentiating Human Neuroblastoma CellsQ47818211
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The retinoid X receptor agonist, 9-cis UAB30, inhibits cutaneous T-cell lymphoma proliferation through the SKP2-p27kip1 axis.Q52337679
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The role of cellular motility in the invasion of human neuroblastoma cells with or without N-myc amplification and expressionQ77736685
A novel retinoid X receptor agonist, UAB30, inhibits rhabdomyosarcoma cells in vitroQ89118592
Cancer stem cells and differentiation therapyQ89738365
Focal Adhesion Kinase Inhibition Contributes to Tumor Cell Survival and Motility in Neuroblastoma Patient-Derived XenograftsQ90100923
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UAB30, a novel RXR agonist, decreases tumorigenesis and leptomeningeal disease in group 3 medulloblastoma patient-derived xenograftsQ91072445
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Src is a novel potential off-target of RXR agonists, 9-cis-UAB30 and Targretin, in human breast cancer cellsQ35470139
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Preclinical Evaluation of a Novel RXR Agonist for the Treatment of NeuroblastomaQ35832541
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Effects on gene expression in rat liver after administration of RXR agonists: UAB30, 4-methyl-UAB30, and Targretin (Bexarotene).Q36642371
Valproic acid overcomes hypoxia-induced resistance to apoptosis.Q36642574
Transient treatment with epigenetic modifiers yields stable neuroblastoma stem cells resembling aggressive large-cell neuroblastomasQ36762610
Preclinical Evaluation of UAB30 in Pediatric Renal and Hepatic MalignanciesQ36917809
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Induced differentiation inhibits sphere formation in neuroblastomaQ38764733
CD133 expression is associated with poor outcome in neuroblastoma via chemoresistance mediated by the AKT pathwayQ39384559
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Comparison of the Side Populations in Pretreatment and Postrelapse Neuroblastoma Cell LinesQ39670555
Quantitative assessment of neurite outgrowth in human embryonic stem cell-derived hN2 cells using automated high-content image analysisQ39734349
Resistance of stem-like cells from neuroblastoma cell lines to commonly used chemotherapeutic agentsQ39772497
Retinoic acid downregulates Rae1 leading to APC(Cdh1) activation and neuroblastoma SH-SY5Y differentiationQ40021807
Factors associated with recurrence and survival length following relapse in patients with neuroblastomaQ40518791
Nestin is a potential mediator of malignancy in human neuroblastoma cellsQ40561244
Expression of class III beta-tubulin in normal and neoplastic human tissuesQ41051476
Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitroQ41665140
Neurite outgrowth and cell cycle kinetic changes induced by cis-diamminedichloroplatinum II and retinoic acid in a human neuroblastoma cell line.Q41727824
13-cis-retinoic acid (NSC 122758) in the treatment of children with metastatic neuroblastoma unresponsive to conventional chemotherapy: report from the Childrens Cancer Study Group.Q41950761
CDDO and ATRA Instigate Differentiation of IMR32 Human Neuroblastoma CellsQ42227825
Combination therapies improve the anticancer activities of retinoids in neuroblastomaQ43134812
P4510describes a project that usesImageJQ1659584
P433issue1
P921main subjectneuroblastomaQ938205
P304page(s)100893
P577publication date2020-09-30
P1433published inTranslational OncologyQ26839583
P1476title9-cis-UAB30, a novel rexinoid agonist, decreases tumorigenicity and cancer cell stemness of human neuroblastoma patient-derived xenografts
P478volume14

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