RAC2 GEFs activate RAC2

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9014296)

RAC2 GEFs activate RAC2 is …
instance of (P31):
biological processQ2996394

External links are
P2888exact matchhttps://identifiers.org/reactome:R-HSA-9014296
P3937Reactome IDR-HSA-9014296

P2860cites workParallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxisQ24646926
SWAP-70 regulates c-kit-induced mast cell activation, cell-cell adhesion, and migrationQ28586573
Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in DrosophilaQ30168983
Dock10, a Cdc42 and Rac1 GEF, induces loss of elongation, filopodia, and ruffles in cervical cancer epithelial HeLa cellsQ30384805
The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosisQ30411888
Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family.Q33831776
DEF6, a novel PH-DH-like domain protein, is an upstream activator of the Rho GTPases Rac1, Cdc42, and RhoA.Q34306137
P-Rex1 regulates neutrophil functionQ34461892
P-Rex1 is a primary Rac2 guanine nucleotide exchange factor in mouse neutrophilsQ34461899
Membrane translocation of P-Rex1 is mediated by G protein betagamma subunits and phosphoinositide 3-kinaseQ34663219
Specific recognition of Rac2 and Cdc42 by DOCK2 and DOCK9 guanine nucleotide exchange factorsQ34721239
The Rac effector p67phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activityQ35641633
Vav proteins control MyD88-dependent oxidative burstQ35751091
The distinct role of guanine nucleotide exchange factor Vav1 in Bcl-2 transcription and apoptosis inhibition in Jurkat leukemia T cellsQ37729845
RNA-aptamers that modulate the RhoGEF activity of Tiam1.Q38314917
The gene for a new brain specific RhoA exchange factor maps to the highly unstable chromosomal region 1p36.2-1p36.3.Q40769216
Deciphering the molecular and functional basis of Dbl family proteins: a novel systematic approach toward classification of selective activation of the Rho family proteinsQ42158425
Comparative functional analysis of the Rac GTPasesQ44693557
Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation.Q46810930
Rac function and regulation during Drosophila development.Q52122073
Asef is a Cdc42-specific guanine nucleotide exchange factorQ79532506
P703found in taxonHomo sapiensQ15978631
P527has part(s)GTP(4−)Q27117191
GDP(3−)Q27125487
RAC2:GTP [plasma membrane]Q100147016
RAC2:GDP [plasma membrane]Q106512999
RAC2 GEFs [cytosol]Q106513000
P361part ofRAC2 GTPase cycleQ106520263

Reverse relations

part of (P361)
Q106513000RAC2 GEFs [cytosol]
Q106512999RAC2:GDP [plasma membrane]
Q100147016RAC2:GTP [plasma membrane]

Q106520263RAC2 GTPase cyclehas part(s)P527

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