Atsushi Ohtsu

Japanese medical researcher

Atsushi Ohtsu is …
instance of (P31):
humanQ5

P27country of citizenshipJapanQ17
P108employerNational Cancer Center Hospital EastQ55454195
P106occupationresearcherQ1650915

Reverse relations

author (P50)
Q5308140512-Gene Recurrence Score Assay Stratifies the Recurrence Risk in Stage II/III Colon Cancer With Surgery Alone: The SUNRISE Study.
Q35022783A Case of Descending Necrotizing MediastinitisPenetrating to the Esophagus
Q37578324A Phase I study of intravenous PI3K inhibitor copanlisib in Japanese patients with advanced or refractory solid tumors
Q44327458A Phase II study of irinotecan in combination with 120-h infusion of 5-fluorouracil in patients with metastatic colorectal carcinoma: Japan Clinical Oncology Group Study (JCOG9703).
Q47597026A Proposal for Progression-Free Survival Assessment in Patients with Early Progressive Cancer
Q33596564A laterally-spreading tumor in a colonic interposition treated by endoscopic submucosal dissection
Q78029389A model chemosensitivity test examining apoptosis in small specimens of gastric cancer
Q53097011A multicenter phase II study of TAS-102 monotherapy in patients with pre-treated advanced gastric cancer (EPOC1201).
Q77847731A new technique for endoscopic mucosal resection with an insulated-tip electrosurgical knife improves the completeness of resection of intramucosal gastric neoplasms
Q88055520A novel gene-protein assay for evaluating HER2 status in gastric cancer: simultaneous analyses of HER2 protein overexpression and gene amplification reveal intratumoral heterogeneity
Q38393041A phase I study evaluating cixutumumab, a type 1 insulin-like growth factor receptor inhibitor, given every 2 or 3 weeks in Japanese patients with advanced solid tumors
Q37028989A phase I study of intravenous aflibercept with FOLFIRI in Japanese patients with previously treated metastatic colorectal cancer
Q86494622A phase I study of sorafenib in combination with S-1 plus cisplatin in patients with advanced gastric cancer
Q33431483A phase I study of the human anti-activin receptor-like kinase 1 antibody PF-03446962 in Asian patients with advanced solid tumors
Q83900980A phase II study of biweekly mitomycin C and irinotecan combination therapy in patients with fluoropyrimidine-resistant advanced gastric cancer: a report from the Gastrointestinal Oncology Group of the Japan Clinical Oncology Group (JCOG0109-DI Tria
Q33341964A phase II study of doxifluridine in elderly patients with advanced gastric cancer: the Japan Clinical Oncology Group Study (JCOG 9410).
Q46564784A phase II study of sequential methotrexate and 5-fluorouracil chemotherapy in previously treated gastric cancer: a report from the Gastrointestinal Oncology Group of the Japan Clinical Oncology Group, JCOG 9207 trial
Q83447218A pilot study of post-operative radiotherapy with concurrent chemotherapy for high-risk squamous cell carcinoma of the cervical esophagus
Q37038184A prospective, multicenter phase I/II study of induction chemotherapy with docetaxel, cisplatin and fluorouracil (DCF) followed by chemoradiotherapy in patients with unresectable locally advanced esophageal carcinoma.
Q35368335A retrospective observational study of clinicopathological features of KRAS, NRAS, BRAF and PIK3CA mutations in Japanese patients with metastatic colorectal cancer
Q46842746A retrospective study of definitive chemoradiotherapy for elderly patients with esophageal cancer
Q49302498A retrospective study of the safety and efficacy of paclitaxel plus ramucirumab in patients with advanced or recurrent gastric cancer with ascites
Q39755186Additional surgery for non-curative resection after endoscopic submucosal dissection for gastric cancer: a retrospective analysis of 200 cases
Q43273259Additive effects of drug transporter genetic polymorphisms on irinotecan pharmacokinetics/pharmacodynamics in Japanese cancer patients
Q42625923Adjuvant therapy with imatinib mesylate after resection of primary high-risk gastrointestinal stromal tumors in Japanese patients
Q43955817Advanced esophageal cancer with esophago-bronchial fistula successfully treated by chemoradiation therapy with additional endoscopic resection: a case report
Q38971256Advances in Systemic Therapy for Metastatic or Advanced Gastric Cancer
Q33394763Amrubicin for the treatment of neuroendocrine carcinoma of the gastrointestinal tract: a retrospective analysis of five cases
Q38924049Analysis of esophagogastric cancer patients enrolled in the National Cancer Institute Cancer Therapy Evaluation Program sponsored phase 1 trials
Q36530731Analysis of neurosensory adverse events induced by FOLFOX4 treatment in colorectal cancer patients: a comparison between two Asian studies and four Western studies
Q28542007Application of a combination of a knowledge-based algorithm and 2-stage screening to hypothesis-free genomic data on irinotecan-treated patients for identification of a candidate single nucleotide polymorphism related to an adverse effect
Q33885980Artificially induced epithelial-mesenchymal transition in surgical subjects: its implications in clinical and basic cancer research
Q44177086Association between aldehyde dehydrogenase gene polymorphisms and the phenomenon of field cancerization in patients with head and neck cancer
Q34026252Association of carboxylesterase 1A genotypes with irinotecan pharmacokinetics in Japanese cancer patients
Q44151716Association of multiple Lugol-voiding lesions with synchronous and metachronous esophageal squamous cell carcinoma in patients with head and neck cancer
Q90587058Association of quality of life with disease characteristics and treatment outcomes in patients with advanced gastric cancer: Exploratory analysis of RAINBOW and REGARD phase III trials
Q90068692Associations of quality of life (QoL) with adverse events and tumor response in patients with advanced gastric cancer: Exploratory analyses from RAINBOW and REGARD
Q84078596Bevacizumab in combination with chemotherapy as first-line therapy in advanced gastric cancer: a biomarker evaluation from the AVAGAST randomized phase III trial
Q29620647Bevacizumab in combination with chemotherapy as first-line therapy in advanced gastric cancer: a randomized, double-blind, placebo-controlled phase III study
Q38413485Biased discordance of KRAS mutation detection in archived colorectal cancer specimens between the ARMS-Scorpion method and direct sequencing
Q44722187Biological markers as a predictor for response and prognosis of unresectable gastric cancer patients treated with irinotecan and cisplatin
Q91299957Biomarker analysis of the GATSBY study of trastuzumab emtansine versus a taxane in previously treated HER2-positive advanced gastric/gastroesophageal junction cancer
Q43860636Biopsy specimen microvessel density is a useful prognostic marker in patients with T(2-4)M(0) esophageal cancer treated with chemoradiotherapy.
Q74531162Carcinoma coexisting with esophageal leiomyoma
Q83144606Causal relationships between esophageal squamous cell carcinoma and nephrotic syndrome
Q112801454Characterization of the large‐scale Japanese patient‐derived xenograft (J‐PDX) library
Q35992591Chemoradiotherapy for esophageal cancer: current status and perspectives
Q37155553Chemotherapy for metastatic gastric cancer: past, present, and future
Q36076767Chemotherapy induced neutropenia at 1-month mark is a predictor of overall survival in patients receiving TAS-102 for refractory metastatic colorectal cancer: a cohort study.
Q89974878Chronological change in chemo-biologic therapy, gastrointestinal cancer
Q44351463Clinical impact of criteria for complete response (CR) of primary site to treatment of esophageal cancer
Q37643988Clinical impact of surveillance for head and neck cancer in patients with esophageal squamous cell carcinoma
Q46102946Clinical outcome of Japanese metastatic colorectal cancer patients harbouring the KRAS p.G13D mutation treated with cetuximab + irinotecan
Q53577839Clinical outcomes in 66 patients with advanced gastric cancer treated in phase I trials: the NCCHE experience.
Q47109685Clinical significance of BRAF non-V600E mutations on the therapeutic effects of anti-EGFR monoclonal antibody treatment in patients with pretreated metastatic colorectal cancer: the Biomarker Research for anti-EGFR monoclonal Antibodies by Comprehen
Q100455164Clinical utility of circulating tumor DNA sequencing in advanced gastrointestinal cancer: SCRUM-Japan GI-SCREEN and GOZILA studies
Q61805291Clinicopathological and molecular features of responders to nivolumab for patients with advanced gastric cancer
Q54977341Clinicopathological features of 22C3 PD-L1 expression with mismatch repair, Epstein-Barr virus status, and cancer genome alterations in metastatic gastric cancer.
Q89975256Clinicopathological features of PD-L1 expression with MMR, EBV status and cancer genome alterations in MGC
Q40581214Clinicopathological features of programmed death ligand 1 expression with tumor-infiltrating lymphocyte, mismatch repair, and Epstein-Barr virus status in a large cohort of gastric cancer patients
Q50727268Clinicopathological, endoscopic, and molecular characteristics of the "skirt" - a new entity of lesions at the margin of laterally spreading tumors.
Q34871466Close association of UGT1A9 IVS1+399C>T with UGT1A1*28, *6, or *60 haplotype and its apparent influence on 7-ethyl-10-hydroxycamptothecin (SN-38) glucuronidation in Japanese
Q64064250Comparative sequence analysis of patient-matched primary colorectal cancer, metastatic, and recurrent metastatic tumors after adjuvant FOLFOX chemotherapy
Q38882202Comparison between neoadjuvant chemotherapy followed by surgery and definitive chemoradiotherapy for overall survival in patients with clinical Stage II/III esophageal squamous cell carcinoma (JCOG1406-A).
Q53645618Comparison of HER2 gene amplification assessed by fluorescence in situ hybridization and HER2 protein expression assessed by immunohistochemistry in gastric cancer.
Q37565108Comprehensive immunohistochemical analysis of tumor microenvironment immune status in esophageal squamous cell carcinoma
Q53631316Computer-assisted analysis of biopsy specimen microvessels predicts the outcome of esophageal cancers treated with chemoradiotherapy.
Q36244592Concordance between PIK3CA mutations in endoscopic biopsy and surgically resected specimens of esophageal squamous cell carcinoma
Q35811012Construction of possible integrated predictive index based on EGFR and ANXA3 polymorphisms for chemotherapy response in fluoropyrimidine-treated Japanese gastric cancer patients using a bioinformatic method
Q79099814Controversies in the treatment of esophageal cancer from the viewpoint of medical oncology
Q43518078Correlation between overall survival and other endpoints in clinical trials of second-line chemotherapy for patients with advanced gastric cancer
Q53256823Current progress of cancer chemotherapy The Fifteenth International Symposium of the Hiroshima Cancer Seminar, October 2005.
Q36112140Current status and future prospects of chemotherapy for metastatic gastric cancer: a review
Q34012967Depressed-type (0-IIc) colorectal neoplasm in patients with family history of first-degree relatives with colorectal cancer: A cross-sectional study
Q30785622Determination of prognostic factors in Japanese patients with advanced gastric cancer using the data from a randomized controlled trial, Japan clinical oncology group 9912.
Q36472210Disparities in gastric cancer chemotherapy between the East and West
Q37141671Diverse eastern and Western approaches to the management of gastric cancer.
Q44178319Docetaxel and cisplatin in patients with advanced or recurrent gastric cancer: a multicenter phase I/II study
Q43262124Does daily alcohol and/or cigarette consumption cause low-grade dysplasia, a precursor of esophageal squamous cell carcinoma?
Q46567504Dose-escalation study for the targeting of CD44v+ cancer stem cells by sulfasalazine in patients with advanced gastric cancer (EPOC1205).
Q43206971EGFR gene alterations as a prognostic biomarker in advanced esophageal squamous cell carcinoma
Q73600851EMR as salvage treatment for patients with locoregional failure of definitive chemoradiotherapy for esophageal cancer
Q84421532Early clinical outcomes of anal squamous cell carcinoma treated with concurrent chemoradiotherapy with 5-Fluorouracil plus mitomycin C in Japanese patients: experience at a single institution
Q47237727Effect of RECIST revision on classification of target lesions and overall response in advanced gastric cancer patients.
Q37146675Effect of food on the pharmacokinetics of TAS-102 and its efficacy and safety in patients with advanced solid tumors
Q98575125Effect of trifluridine/tipiracil in patients treated in RECOURSE by prognostic factors at baseline: an exploratory analysis
Q90075055Efficacy and Long-term Peripheral Sensory Neuropathy of 3 vs 6 Months of Oxaliplatin-Based Adjuvant Chemotherapy for Colon Cancer: The ACHIEVE Phase 3 Randomized Clinical Trial
Q36767776Efficacy and safety of capecitabine plus cisplatin in Japanese patients with advanced or metastatic gastric cancer: subset analyses of the AVAGAST study and the ToGA study
Q58694204Efficacy and safety of ramucirumab-containing chemotherapy in patients with pretreated metastatic gastric neuroendocrine carcinoma
Q44328704Efficacy and safety profile of S-1 in patients with metastatic gastric cancer in clinical practice: results from a post-marketing survey
Q46540756Efficacy and safety profile of imatinib mesylate (ST1571) in Japanese patients with advanced gastrointestinal stromal tumors: a phase II study (STI571B1202).
Q39393733Efficacy of chemoradiotherapy on pain relief in patients with intrapelvic recurrence of rectal cancer
Q84531236Efficacy of concurrent chemoradiotherapy as a palliative treatment in stage IVB esophageal cancer patients with dysphagia
Q47358505Efficacy of preventive endoscopic balloon dilation for esophageal stricture after endoscopic resection
Q36078921Efficacy of trastuzumab in Japanese patients with HER2-positive advanced gastric or gastroesophageal junction cancer: a subgroup analysis of the Trastuzumab for Gastric Cancer (ToGA) study
Q45201267Eight novel single nucleotide polymorphisms in ABCG2/BCRP in Japanese cancer patients administered irinotacan
Q51676975Elective nodal irradiation (ENI) in definitive chemoradiotherapy (CRT) for squamous cell carcinoma of the thoracic esophagus.
Q84033838Endoscopic balloon dilatation for benign fibrotic strictures after curative nonsurgical treatment for esophageal cancer
Q53565118Endoscopic submucosal dissection using a new scissors-type electrosurgical knife: a first-in-human feasibility study.
Q35674222Enhanced antitumor effect of anti-tissue factor antibody-conjugated epirubicin-incorporating micelles in xenograft models.
Q53226764Epidermoid metaplasia of the esophagus: endoscopic feature and differential diagnosis.
Q43725087Epstein-Barr virus involvement is a predictive factor for the resistance to chemoradiotherapy of gastric diffuse large B-cell lymphoma
Q46984592Erratum to: Efficacy and safety of capecitabine plus cisplatin in Japanese patients with advanced or metastatic gastric cancer: subset analyses of the AVAGAST study and the ToGA study.
Q78853372Esophageal stenosis after endoscopic mucosal resection of superficial esophageal lesions
Q92814580Establishment of Novel Gastric Cancer Patient-Derived Xenografts and Cell Lines: Pathological Comparison between Primary Tumor, Patient-Derived, and Cell-Line Derived Xenografts
Q33399121Evaluation of safety, pharmacokinetics, and efficacy of vorinostat, a histone deacetylase inhibitor, in the treatment of gastrointestinal (GI) cancer in a phase I clinical trial
Q55322223Everolimus for previously treated advanced gastric cancer: results of the randomized, double-blind, phase III GRANITE-1 study.
Q53158332Exposure-Response Analyses of Ramucirumab from Two Randomized, Phase III Trials of Second-line Treatment for Advanced Gastric or Gastroesophageal Junction Cancer.
Q54400420Exposure-response relationship of ramucirumab in East Asian patients from RAINBOW: a randomized clinical trial in second-line treatment of gastric cancer.
Q44679439Expression of thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase, E2F-1, Bak, Bcl-X, and Bcl-2, and clinical outcomes for gastric cancer patients treated with bolus 5-fluorouracil
Q54218339Expression profiles of HER2, EGFR, MET and FGFR2 in a large cohort of patients with gastric adenocarcinoma.
Q83311812Expression profiling of esophageal squamous cell carcinoma patients treated with definitive chemoradiotherapy: clinical implications
Q84705705Feasibility and robustness of amplification refractory mutation system (ARMS)-based KRAS testing using clinically available formalin-fixed, paraffin-embedded samples of colorectal cancers
Q43414868Feasibility of oxaliplatin and infusional fluorouracil/leucovorin (FOLFOX4) for Japanese patients with unresectable metastatic colorectal cancer
Q78029438Five-year survivor with liver metastasis from gastric cancer successfully treated with systemic chemotherapy
Q43264239Fluorouracil versus combination of irinotecan plus cisplatin versus S-1 in metastatic gastric cancer: a randomised phase 3 study
Q79551981Fourteen novel genetic variations and haplotype structures of the TYMS gene encoding human thymidylate synthase (TS)
Q44429351Functional Characterization of Human UDP-Glucuronosyltransferase 1A9 Variant, D256N, Found in Japanese Cancer Patients
Q28191037Functional Characterization of Wild-type and Variant (T202I and M59I) Human UDP-glucuronosyltransferase 1A10
Q46577270Functional analysis of four naturally occurring variants of human constitutive androstane receptor
Q46463070Functional analysis of six human aryl hydrocarbon receptor variants in a Japanese population
Q40395346Functional characterization of three naturally occurring single nucleotide polymorphisms in the CES2 gene encoding carboxylesterase 2 (HCE-2).
Q42876512Gastric Cancer Working Group Report
Q54477942Gastrointestinal Perforation and Fistula Formation in 5 Patients With Colorectal Cancer During Treatment With Regorafenib.
Q42365301Gene expression profiling to predict recurrence of advanced squamous cell carcinoma of the tongue: discovery and external validation
Q39295199Genetic polymorphisms of FCGR2A encoding Fcγ receptor IIa in a Japanese population and functional analysis of the L273P variant.
Q85171688Genetic polymorphisms of FCGRT encoding FcRn in a Japanese population and their functional analysis
Q81527569Genetic polymorphisms of UGT1A6 in a Japanese population
Q82383679Genetic polymorphisms of copper- and platinum drug-efflux transporters ATP7A and ATP7B in Japanese cancer patients
Q83349894Genetic variation and haplotype structure of the ABC transporter gene ABCG2 in a Japanese population
Q80408458Genetic variations and frequencies of major haplotypes in SLCO1B1 encoding the transporter OATP1B1 in Japanese subjects: SLCO1B1*17 is more prevalent than *15
Q81166532Genetic variations and haplotype structures of the DPYD gene encoding dihydropyrimidine dehydrogenase in Japanese and their ethnic differences
Q46619620Genetic variations and haplotypes of ABCC2 encoding MRP2 in a Japanese population
Q81691372Genetic variations and haplotypes of UGT1A4 in a Japanese population
Q80895328Genetic variations of the AHR gene encoding aryl hydrocarbon receptor in a Japanese population
Q38465629Globalization of clinical trials
Q38347530Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan
Q47296992Haplotypes of CYP3A4 and their close linkage with CYP3A5 haplotypes in a Japanese population.
Q90355846Histopathological factors affecting the extraction of high quality genomic DNA from tissue sections for next-generation sequencing
Q30652586Identification of a candidate single-nucleotide polymorphism related to chemotherapeutic response through a combination of knowledge-based algorithm and hypothesis-free genomic data.
Q46907839Impact of CYP3A4 haplotypes on irinotecan pharmacokinetics in Japanese cancer patients
Q50581166Impaired mental health among the bereaved spouses of cancer patients.
Q44027420Implantation of self-expanding metallic stent for patients with malignant stricture after failure of definitive chemoradiotherapy for T3 or T4 esophageal squamous cell carcinomas.
Q48451787Induction chemotherapy with docetaxel, cisplatin and S-1 followed by proton beam therapy concurrent with cisplatin in patients with T4b nasal and sinonasal malignancies
Q35799385Initial safety report on the tolerability of modified FOLFOX6 as adjuvant therapy in patients with curatively resected stage II or III colon cancer (JFMC41-1001-C2: JOIN trial)
Q47412558Integrated safety summary for trifluridine/tipiracil (TAS-102).
Q80452767Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A1*6 and *28
Q90247055JOIN trial: treatment outcome and recovery status of peripheral sensory neuropathy during a 3-year follow-up in patients receiving modified FOLFOX6 as adjuvant treatment for stage II/III colon cancer
Q46548601Japanese multicenter phase II study of CHOP followed by radiotherapy in stage I-II, diffuse large B-cell lymphoma of the stomach
Q45300740Japanese nationwide post-marketing survey of S-1 in patients with advanced gastric cancer
Q91685811KEYNOTE-585: Phase III study of perioperative chemotherapy with or without pembrolizumab for gastric cancer
Q27853010Lapatinib plus paclitaxel versus paclitaxel alone in the second-line treatment of HER2-amplified advanced gastric cancer in Asian populations: TyTAN--a randomized, phase III study
Q110566364Large-scale analyses of tumor mutation burdens (TMBs) across various advanced gastrointestinal (GI) malignancies in the nationwide cancer genome screening project, SCRUM-Japan GI-SCREEN
Q48012424Large-scale comprehensive immunohistochemical biomarker analyses in esophageal squamous cell carcinoma
Q36625694Local efficacy and survival outcome of salvage endoscopic therapy for local recurrent lesions after definitive chemoradiotherapy for esophageal cancer
Q81436311Local recurrence of squamous-cell carcinoma of the esophagus after EMR
Q90237892Long-term efficacy and predictive correlates of response to nivolumab in Japanese patients with esophageal cancer
Q48252275Long-term outcome of transoral organ-preserving pharyngeal endoscopic resection for superficial pharyngeal cancer.
Q80676121Long-term outcomes of patients with metastatic gastric cancer after initial S-1 monotherapy
Q34620968Long-term results for patients with unresectable gastric cancer who received chemotherapy in the Japan Clinical Oncology Group (JCOG) trials
Q45197528Long-term survival and prognostic factors in patients with metastatic gastric cancers treated with chemotherapy in the Japan Clinical Oncology Group (JCOG) study
Q44513217Long-term toxicity after definitive chemoradiotherapy for squamous cell carcinoma of the thoracic esophagus
Q83065708Magnifying narrow-band imaging versus magnifying white-light imaging for the differential diagnosis of gastric small depressive lesions: a prospective study
Q37709811Multicenter phase II study of everolimus in patients with previously treated metastatic gastric cancer
Q37692114NC-6004 Phase I study in combination with gemcitabine for advanced solid tumors and population PK/PD analysis.
Q49351167Napabucasin versus placebo in refractory advanced colorectal cancer: a randomised phase 3 trial
Q44458774Neoadjuvant chemotherapy with S-1 for scirrhous gastric cancer: a pilot study
Q40289794Nivolumab treatment for oesophageal squamous-cell carcinoma: an open-label, multicentre, phase 2 trial
Q53209050Non-surgical approach to small cell carcinoma of the esophagus: does this rare disease have the same tumor behavior as SCLC?
Q46812542Nonplatinum-based chemotherapy with irinotecan plus docetaxel for advanced or metastatic olfactory neuroblastoma: a retrospective analysis of 12 cases.
Q44574465Nonrandomized comparison between definitive chemoradiotherapy and radical surgery in patients with T(2-3)N(any) M(0) squamous cell carcinoma of the esophagus
Q57273153Novel Genetic Polymorphisms in the NR3C1 (Glucocorticoid receptor) Gene in a Japanese Population
Q82204627Overview of adjuvant therapy for resected gastric cancer: differences in Japan and the United States
Q37615896Panitumumab in Japanese patients with unresectable colorectal cancer: a post-marketing surveillance study of 3085 patients
Q39769463Patients' perception of the usefulness of a question prompt sheet for advanced cancer patients when deciding the initial treatment: a randomized, controlled trial
Q89029141Pembrolizumab versus paclitaxel for previously treated, advanced gastric or gastro-oesophageal junction cancer (KEYNOTE-061): a randomised, open-label, controlled, phase 3 trial
Q41595469Peritonitis related to percutaneous endoscopic gastrostomy using the direct method for cancer patients.
Q91456012Pertuzumab plus trastuzumab and chemotherapy for HER2-positive metastatic gastric or gastro-oesophageal junction cancer (JACOB): final analysis of a double-blind, randomised, placebo-controlled phase 3 study
Q58614911Pharmacodynamic Studies of Gefitinib in Tumor Biopsy Specimens From Patients With Advanced Gastric Carcinoma
Q54547540Pharmacokinetic analysis of capecitabine and cisplatin in combination with trastuzumab in Japanese patients with advanced HER2-positive gastric cancer.
Q92648000Pharmacokinetic and exposure-response analysis of pertuzumab in patients with HER2-positive metastatic gastric or gastroesophageal junction cancer
Q54393532Pharmacokinetics, safety, and efficacy of FOLFIRI plus bevacizumab in Japanese colorectal cancer patients with UGT1A1 gene polymorphisms.
Q37121517Phase 1 pharmacokinetic study of MK-0646 (dalotuzumab), an anti-insulin-like growth factor-1 receptor monoclonal antibody, in combination with cetuximab and irinotecan in Japanese patients with advanced colorectal cancer
Q35889628Phase 1 pharmacokinetic study of the oral pan-AKT inhibitor MK-2206 in Japanese patients with advanced solid tumors
Q33710548Phase 1 study of efatutazone, a novel oral peroxisome proliferator-activated receptor gamma agonist, in combination with FOLFIRI as second-line therapy in patients with metastatic colorectal cancer
Q33402421Phase 1 study of ganitumab (AMG 479), a fully human monoclonal antibody against the insulin-like growth factor receptor type I (IGF1R), in Japanese patients with advanced solid tumors
Q52773451Phase 1 study of sulfasalazine and cisplatin for patients with CD44v-positive gastric cancer refractory to cisplatin (EPOC1407).
Q36503472Phase 1 study of trebananib (AMG 386), an angiogenesis targeting angiopoietin-1/2 antagonist, in Japanese patients with advanced solid tumors
Q54599564Phase 2 study of nilotinib as third-line therapy for patients with gastrointestinal stromal tumor.
Q42859969Phase I Study of NK012, a Novel SN-38–Incorporating Micellar Nanoparticle, in Adult Patients with Solid Tumors
Q33566872Phase I clinical and pharmacokinetic study of RAD001 (everolimus) administered daily to Japanese patients with advanced solid tumors
Q35051964Phase I dose-escalation study of buparlisib (BKM120), an oral pan-class I PI3K inhibitor, in Japanese patients with advanced solid tumors
Q34085148Phase I dose-escalation study of the HSP90 inhibitor AUY922 in Japanese patients with advanced solid tumors
Q92455704Phase I dose-escalation study of the safety, tolerability, and pharmacokinetics of aflibercept in combination with S-1 in Japanese patients with advanced solid malignancies
Q36621566Phase I study of TAS-102 and irinotecan combination therapy in Japanese patients with advanced colorectal cancer
Q35051852Phase I study of olaratumab in Japanese patients with advanced solid tumors
Q83347957Phase I study of single-dose oxaliplatin in Japanese patients with malignant tumors
Q33400146Phase I study of sunitinib plus modified FOLFOX6 in Japanese patients with treatment-naive colorectal cancer.
Q82751720Phase I trial of chemoradiotherapy with the combination of S-1 plus cisplatin for patients with unresectable locally advanced squamous cell carcinoma of the head and neck
Q33371147Phase I/II study of oxaliplatin with weekly bolus fluorouracil and high-dose leucovorin (ROX) as first-line therapy for patients with colorectal cancer
Q84869381Phase I/II study of radiologic hepatic arterial infusion of fluorouracil plus systemic irinotecan for unresectable hepatic metastases from colorectal cancer: Japan Clinical Oncology Group Trial 0208-DI
Q43281012Phase I/II study of sunitinib malate in Japanese patients with gastrointestinal stromal tumor after failure of prior treatment with imatinib mesylate
Q33424985Phase I/II trial of chemoradiotherapy with concurrent S-1 and cisplatin for clinical stage II/III esophageal carcinoma (JCOG 0604)
Q51538482Phase II Study of Chemoradiotherapy With 5-Fluorouracil and Cisplatin for Stage II–III Esophageal Squamous Cell Carcinoma: JCOG Trial (JCOG 9906)
Q53149355Phase II feasibility trial of adjuvant chemoradiotherapy with 3-weekly cisplatin for Japanese patients with post-operative high-risk squamous cell carcinoma of the head and neck.
Q33348280Phase II study of biweekly irinotecan and mitomycin C combination therapy in patients with fluoropyrimidine-resistant advanced colorectal cancer
Q44908377Phase II study of oral S-1 for treatment of metastatic colorectal carcinoma
Q33376015Phase II study of oxaliplatin in japanese patients with metastatic colorectal cancer refractory to fluoropyrimidines
Q45034321Phase II study of sequential methotrexate and 5-fluorouracil chemotherapy against peritoneally disseminated gastric cancer with malignant ascites: a report from the Gastrointestinal Oncology Study Group of the Japan Clinical Oncology Group, JCOG 960
Q34056960Photodynamic therapy as salvage treatment for local failure after chemoradiotherapy in patients with esophageal squamous cell carcinoma: a phase II study.
Q30787014Photodynamic therapy as salvage treatment for local failures after definitive chemoradiotherapy for esophageal cancer
Q93086621Poster abstracts of the 18th Pan Arab Cancer Congress. TUNISIA. April 19-21, 2018
Q37706868Preclinical efficacy of Sym004, novel anti-EGFR antibody mixture, in esophageal squamous cell carcinoma cell lines.
Q90975662Predictive factors for hyperprogressive disease during nivolumab as anti-PD1 treatment in patients with advanced gastric cancer
Q44629355Present status of chemotherapy for colorectal cancer in countries outside of Japan
Q33849290Prognostic Factor Analysis of Overall Survival in Gastric Cancer from Two Phase III Studies of Second-line Ramucirumab (REGARD and RAINBOW) Using Pooled Patient Data
Q39038837Prognostic impact of HER2, EGFR, and c-MET status on overall survival of advanced gastric cancer patients
Q39834652Prognostic significance of tumor regression grade for patients with esophageal squamous cell carcinoma after neoadjuvant chemotherapy followed by surgery
Q43870660Progression-free survival and post-progression survival in patients with advanced gastric cancer treated with first-line chemotherapy
Q37197679Progression-free survival as a surrogate for overall survival in advanced/recurrent gastric cancer trials: a meta-analysis
Q51750620Prophylactic Use of Oral Dexamethasone to Alleviate Fatigue During Regorafenib Treatment for Patients With Metastatic Colorectal Cancer.
Q37528049Prophylactic steroid administration for strictures after endoscopic resection of large superficial esophageal squamous cell carcinoma.
Q89553736Proxies of quality of life in metastatic colorectal cancer: analyses in the RECOURSE trial
Q39625948Psychological states and coping strategies after bereavement among spouses of cancer patients: a quantitative study in Japan
Q33398232Pulmonary tumor thrombotic microangiopathy associated with esophageal squamous cell carcinoma
Q55319545QTWiST analysis of the RECOURSE trial of trifluridine/tipiracil in metastatic colorectal cancer.
Q33829785Quality of life in the trastuzumab for gastric cancer trial
Q38272318Ramucirumab for gastric cancer
Q29620917Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial
Q46350650Randomized Phase III study of 5-fluorouracil continuous infusion vs. sequential methotrexate and 5-fluorouracil therapy in far advanced gastric cancer with peritoneal metastasis (JCOG0106).
Q64109947Randomized phase II study of second-line chemotherapy with the best available 5-fluorouracil regimen versus weekly administration of paclitaxel in far advanced gastric cancer with severe peritoneal metastases refractory to 5-fluorouracil-containing r
Q40613157Randomized phase III trial of fluorouracil alone versus fluorouracil plus cisplatin versus uracil and tegafur plus mitomycin in patients with unresectable, advanced gastric cancer: The Japan Clinical Oncology Group Study (JCOG9205).
Q33417630Randomized phase III trial of regorafenib in metastatic colorectal cancer: analysis of the CORRECT Japanese and non-Japanese subpopulations
Q41741632Randomized trial of TAS-102 for refractory metastatic colorectal cancer
Q91673708Rationale and design of the BRAVERY study (EPOC1701): a multicentre phase II study of eribulin in patients with BRAF V600E mutant metastatic colorectal cancer
Q48569564Regional differences in advanced gastric cancer: exploratory analyses of the AVAGAST placebo arm.
Q91259894Relationship Between Thymidine Kinase 1 Expression and Trifluridine/Tipiracil Therapy in Refractory Metastatic Colorectal Cancer: A Pooled Analysis of 2 Randomized Clinical Trials
Q38951620Relationship between Pulmonary Adverse Events and Everolimus Exposure in Japanese and Non-Japanese Patients: A Meta-Analysis of Oncology Trials.
Q80730902Relationship between expression of vascular endothelial growth factor in tumor tissue from gastric cancers and chemotherapy effects: comparison between S-1 alone and the combination of S-1 plus CDDP
Q91422883Relationship between the immune microenvironment of different locations in a primary tumour and clinical outcomes of oesophageal squamous cell carcinoma
Q26766039Report on the use of non-clinical studies in the regulatory evaluation of oncology drugs
Q42730356Retrospective analysis of antiemetic effect in patients receiving cisplatin
Q45271628Risk of multiple squamous cell carcinomas both in the esophagus and the head and neck region
Q110566220SCRUM-Japan GI-SCREEN and MONSTAR-SCREEN: Path to the realization of biomarker-guided precision oncology in advanced solid tumors
Q34023788Safety analysis of FOLFOX4 treatment in colorectal cancer patients: a comparison between two Asian studies and four Western studies
Q53837214Safety and Efficacy of Pembrolizumab Monotherapy in Patients With Previously Treated Advanced Gastric and Gastroesophageal Junction Cancer: Phase 2 Clinical KEYNOTE-059 Trial.
Q87001982Safety and Efficacy of Trifluridine/Tipiracil Monotherapy in Clinical Practice for Patients With Metastatic Colorectal Cancer: Experience at a Single Institution
Q33423976Safety and Pharmacokinetics of Second-line Ramucirumab plus FOLFIRI in Japanese Patients with Metastatic Colorectal Carcinoma
Q84461270Safety and pharmacokinetics of panitumumab in Japanese patients with advanced solid tumors
Q55073748Safety data from the phase III Japanese ACHIEVE trial: part of an international, prospective, planned pooled analysis of six phase III trials comparing 3 versus 6 months of oxaliplatin-based adjuvant chemotherapy for stage III colon cancer.
Q37157346Safety of irinotecan and infusional fluorouracil/leucovorin (FOLFIRI) in Japan: a retrospective review of 48 patients with metastatic colorectal cancer
Q52900371Salvage photodynamic therapy for local failure after chemoradiotherapy for esophageal squamous cell carcinoma.
Q78029373Sequential methotrexate and 5-fluorouracil therapy for gastric cancer patients with bone metastasis
Q53005714Serum HER2 levels and HER2 status in tumor cells in advanced gastric cancer patients.
Q78029461Significance of and problems in adopting response evaluation criteria in solid tumor RECIST for assessing anticancer effects of advanced gastric cancer
Q80375553Significance of biological markers for predicting prognosis and selecting chemotherapy regimens of advanced gastric cancer patients between continuous infusion of 5-FU and a combination of 5-FU and cisplatin
Q34978610Simultaneous identification of 36 mutations in KRAS codons 61 and 146, BRAF, NRAS, and PIK3CA in a single reaction by multiplex assay kit.
Q48846698Squamous cell carcinoma in situ at oropharyngeal and hypopharyngeal mucosal sites
Q38401300Subgroup analyses of the safety and efficacy of ramucirumab in Japanese and Western patients in RAINBOW: a randomized clinical trial in second-line treatment of gastric cancer
Q41443108Subgroup analysis of East Asians in RAINBOW: A phase 3 trial of ramucirumab plus paclitaxel for advanced gastric cancer.
Q84974747Successful endosocpic submucosal dissection for esophageal squamous cell carcinoma together with a lipoma
Q44012763Survival prolongation after treatment failure of first-line chemotherapy in patients with advanced gastric cancer: combined analysis of the Japan Clinical Oncology group trials JCOG9205 and JCOG9912.
Q34604499Systemic chemotherapy with cisplatin plus 5-FU (PF) for recurrent or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN): efficacy and safety of a lower dose of PF (80/800) at a single institution in Japan.
Q43472706TAS-102 monotherapy for pretreated metastatic colorectal cancer: a double-blind, randomised, placebo-controlled phase 2 trial
Q47308849TAS-102 plus bevacizumab for patients with metastatic colorectal cancer refractory to standard therapies (C-TASK FORCE): an investigator-initiated, open-label, single-arm, multicentre, phase 1/2 study
Q54394567TS gene tandem repeats in esophageal cancer patients receiving chemoradiotherapy.
Q112347109The CLIP1-LTK fusion is an oncogenic driver in non-small-cell lung cancer
Q28681140The IDEA (International Duration Evaluation of Adjuvant Chemotherapy) Collaboration: Prospective Combined Analysis of Phase III Trials Investigating Duration of Adjuvant Therapy with the FOLFOX (FOLFOX4 or Modified FOLFOX6) or XELOX (3 versus 6 [...]
Q46907708The IDEA Collaboration: Prospective Combined Analysis of Phase III Trials Investigating Duration of Adjuvant Therapy with the FOLFOX Regimen for Patients with Stage III Colon Cancer: Current Status
Q110566356The Nationwide Cancer Genome Screening Project in Japan SCRUM-Japan GI-SCREEN: Efficient identification of cancer genome alterations in advanced non-colorectal (Non-CRC) gastrointestinal cancer
Q110566359The Nationwide Cancer Genome Screening Project in Japan SCRUM-Japan, GI-screen: Efficient identification of cancer genome alterations in advanced gastric cancer
Q110566355The Nationwide Cancer Genome Screening Project in Japan, SCRUM-Japan GI-SCREEN: Efficient identification of cancer genome alterations in advanced colorectal cancer
Q110566360The Nationwide Cancer Genome Screening Project in Japan, SCRUM-Japan GI-screen: Efficient identification of cancer genome alterations in advanced esophageal cancer
Q110566354The Nationwide Cancer Genome Screening Projects for Gastrointestinal Cancer in Japan (SCRUM-Japan GI-SCREEN): Efficient identification of actionable cancer genome alterations in advanced colorectal and non-colorectal gastrointestinal cancer (GI Scree
Q35211663The latest advances in chemotherapy for gastrointestinal cancers
Q110566365The nationwide cancer genome screening project in Japan SCRUM-Japan GI-SCREEN: Efficient identification of cancer genome alterations in advanced gastric cancer (GC)
Q35139161The role of chemotherapy in the current treatment of gastric cancer
Q47560805The subgroups of the phase III RECOURSE trial of trifluridine/tipiracil (TAS-102) versus placebo with best supportive care in patients with metastatic colorectal cancer
Q43056334Therapeutic significance of a D-dimer cut-off level of >3 µg/ml in colorectal cancer patients treated with standard chemotherapy plus bevacizumab
Q45201194Three novel single nucleotide polymorphisms in UGT1A10.
Q81197213Three novel single nucleotide polymorphisms in UGT1A9
Q33440401Trastuzumab emtansine versus taxane use for previously treated HER2-positive locally advanced or metastatic gastric or gastro-oesophageal junction adenocarcinoma (GATSBY): an international randomised, open-label, adaptive, phase 2/3 study
Q27851578Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial
Q44012031Treatment strategy for superficial pharyngeal squamous cell carcinoma synchronously combined with esophageal cancer
Q104067114Tumor response and symptom palliation from RAINBOW, a phase 3 trial of ramucirumab plus paclitaxel in previously treated advanced gastric cancer
Q28299967Twelve novel single nucleotide polymorphisms in the CES2 gene encoding human carboxylesterase 2 (hCE-2)
Q50098778Twenty-six novel single nucleotide polymorphisms and their frequencies of the NR1I3 (CAR) gene in a Japanese population
Q44922991UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer
Q50950240Usefulness of endoscopic radial incision and cutting method for refractory esophagogastric anastomotic stricture (with video).
Q110569502Utility of circulating tumor DNA (ctDNA) versus tumor tissue clinical sequencing for enrolling patients (Pts) with advanced gastrointestinal (GI) cancer to matched clinical trials: SCRUM-Japan GI-SCREEN and GOZILA Combined Analysis
Q110569489Utility of circulating tumor DNA (ctDNA) versus tumor tissue clinical sequencing for enrolling patients (pts) with advanced non-colorectal (non-CRC) gastrointestinal (GI) cancer to matched clinical trials: SCRUM-Japan GI-SCREEN and GOZILA combined an
Q110569495Utility of circulating tumor DNA (ctDNA) versus tumor tissue genotyping for enrollment of patients with metastatic colorectal cancer (mCRC) to matched clinical trials: SCRUM-Japan GI-SCREEN and GOZILA combined analysis
Q39203869Vandetanib in patients with previously treated RET-rearranged advanced non-small-cell lung cancer (LURET): an open-label, multicentre phase 2 trial
Q85595137[109th Scientific Meeting of the Japanese Society of Internal Medicine: symposium:1. Recent treatments and progress in malignant tumors--chemotherapy and molecular targeting agents antibody therapy; introduction]
Q83796934[Chemoradiotherapy]
Q86437184[Chemotherapy with molecular targeting agents for colorectal cancer]
Q45951763[Current Status and Future Perspectives of SCRUM-Japan].
Q95621515[Current status and issues in early & exploratory oncology clinical trials in Japan]
Q64967627[Current topics on molecular targeting drugs for gastric cancer].
Q80083618[Japanese nationwide post-marketing survey of S-1 in patients with advanced gastric cancer]
Q57212452[Participation to international registration trials--from the investigator's standpoint]
Q45960431[Two cases of KRAS wild-type unresectable or recurrent colorectal cancer effectively treated by cetuximab after progression of prior chemotherapy].
Q37928535mTOR as a therapeutic target in patients with gastric cancer

Search more.