human | Q5 |
P496 | ORCID iD | 0000-0002-1338-7078 |
P2038 | ResearchGate profile ID | Johan-Es |
P106 | occupation | researcher | Q1650915 |
Q47308901 | A Single-Cell RNA Sequencing Study Reveals Cellular and Molecular Dynamics of the Hippocampal Neurogenic Niche |
Q42152874 | A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal |
Q24338902 | A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta |
Q46832278 | A20 controls intestinal homeostasis through cell-specific activities |
Q50593562 | An EphB-Abl signaling pathway is associated with intestinal tumor initiation and growth. |
Q36155098 | An inducible mouse model for microvillus inclusion disease reveals a role for myosin Vb in apical and basolateral trafficking |
Q35762264 | Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer |
Q89831611 | Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells |
Q95933360 | Assessing the origin of high-grade serous ovarian cancer using CRISPR-modification of mouse organoids |
Q38710117 | Biased competition between Lgr5 intestinal stem cells driven by oncogenic mutation induces clonal expansion. |
Q45847463 | Canonical Wnt signaling negatively modulates regulatory T cell function. |
Q34237942 | Controlled gene expression in primary Lgr5 organoid cultures |
Q39751765 | Conversion of metaplastic Barrett's epithelium into post-mitotic goblet cells by gamma-secretase inhibition |
Q28304418 | Crypt stem cells as the cells-of-origin of intestinal cancer |
Q33742017 | DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus |
Q31110759 | De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data |
Q47961996 | De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine |
Q28506643 | Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand |
Q28300176 | Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium |
Q34637873 | Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium. |
Q37211856 | Dll1+ secretory progenitor cells revert to stem cells upon crypt damage |
Q36675173 | Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation. |
Q92023561 | Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion |
Q90427601 | Enteroendocrine cells switch hormone expression along the crypt-to-villus BMP signalling gradient |
Q57066409 | Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice |
Q38914917 | Generation and analysis of mouse intestinal tumors and organoids harboring APC and K-Ras mutations |
Q37369513 | Generation of an inducible colon-specific Cre enzyme mouse line for colon cancer research |
Q28593397 | HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction |
Q91321638 | Identification of Enteroendocrine Regulators by Real-Time Single-Cell Differentiation Mapping |
Q28131701 | Identification of stem cells in small intestine and colon by marker gene Lgr5 |
Q36791239 | In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration. |
Q34522818 | Inducible in vivo silencing of Brd4 identifies potential toxicities of sustained BET protein inhibition |
Q29619410 | Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells |
Q42739535 | Intestinal stem cells lacking the Math1 tumour suppressor are refractory to Notch inhibitors. |
Q53447869 | Lgr5 marks cycling, yet long-lived, hair follicle stem cells. |
Q34301244 | Lgr5(+ve) stem/progenitor cells contribute to nephron formation during kidney development. |
Q63406949 | Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin |
Q34291885 | Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas |
Q89998661 | Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids |
Q63406947 | Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium |
Q36528951 | Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2. |
Q34332458 | Mapping early fate determination in Lgr5+ crypt stem cells using a novel Ki67-RFP allele |
Q40071670 | Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation |
Q37633867 | Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny |
Q88721108 | Notch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche |
Q91750889 | Oral Mucosal Organoids as a Potential Platform for Personalized Cancer Therapy |
Q91824416 | Pancreatic cancer organoids recapitulate disease and allow personalized drug screening |
Q91202976 | Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling |
Q34425223 | Paneth cells |
Q29616197 | Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts |
Q35764241 | Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia |
Q92304607 | Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids |
Q60911613 | Profiling proliferative cells and their progeny in damaged murine hearts |
Q50614489 | Prominin-1/CD133 marks stem cells and early progenitors in mouse small intestine. |
Q50788436 | Redundant sources of Wnt regulate intestinal stem cells and promote formation of Paneth cells. |
Q37264185 | Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon |
Q38797646 | Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters |
Q35018668 | Retromer dependent recycling of the Wnt secretion factor Wls is dispensable for stem cell maintenance in the mammalian intestinal epithelium |
Q42915923 | Robust cre-mediated recombination in small intestinal stem cells utilizing the olfm4 locus |
Q28586813 | SOX9 is required for the differentiation of paneth cells in the intestinal epithelium |
Q28239639 | Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche |
Q35799683 | Single-molecule transcript counting of stem-cell markers in the mouse intestine |
Q36029963 | T-cell factor 4 (Tcf7l2) maintains proliferative compartments in zebrafish intestine |
Q34122210 | TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling |
Q41698268 | Targeting development of incretin-producing cells increases insulin secretion |
Q21135289 | The BMP antagonist follistatin-like 1 is required for skeletal and lung organogenesis |
Q34280882 | The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers |
Q28507783 | Transcription factor achaete scute-like 2 controls intestinal stem cell fate |
Q47661472 | Troy+ brain stem cells cycle through quiescence and regulate their number by sensing niche occupancy |
Q24296595 | Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors |
Q28298678 | Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis |
Q28593773 | Wnt signalling induces maturation of Paneth cells in intestinal crypts |
Q35062431 | You Wnt some, you lose some: oncogenes in the Wnt signaling pathway |
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