Abstract is: Iron deficiency, or sideropenia, is the state in which a body lacks enough iron to supply its needs. Iron is present in all cells in the human body and has several vital functions, such as carrying oxygen to the tissues from the lungs as a key component of the hemoglobin protein, acting as a transport medium for electrons within the cells in the form of cytochromes, and facilitating oxygen enzyme reactions in various tissues. Too little iron can interfere with these vital functions and lead to morbidity and death. Total body iron averages approximately 3.8 g in men and 2.3 g in women. In blood plasma, iron is carried tightly bound to the protein transferrin. There are several mechanisms that control iron metabolism and safeguard against iron deficiency. The main regulatory mechanism is situated in the gastrointestinal tract. The majority of iron absorption occurs in the duodenum, the first section of the small intestine. A number of dietary factors may affect iron absorption. When loss of iron is not sufficiently compensated by intake of iron from the diet, a state of iron deficiency develops over time. When this state is uncorrected, it leads to iron-deficiency anemia, a common type of anemia. Before anemia occurs, the medical condition of iron deficiency without anemia is called latent iron deficiency (LID). Anemia is a condition characterized by inadequate red blood cells (erythrocytes) or hemoglobin. When the body lacks sufficient amounts of iron, production of the protein hemoglobin is reduced. Hemoglobin binds to oxygen, enabling red blood cells to supply oxygenated blood throughout the body. Women of child-bearing age, children, and people with poor diet are most susceptible to the disease. Most cases of iron-deficiency anemia are mild, but if not treated can cause problems like an irregular heartbeat, pregnancy complications, and delayed growth in infants and children that could affect their cognitive development and their behavior.
| P557 | DiseasesDB | 6947 |
| P673 | eMedicine ID | 202333 |
| P646 | Freebase ID | /m/014x04 |
| P12385 | Gran Enciclopèdia Catalana ID | ferropenia |
| P1296 | Gran Enciclopèdia Catalana ID (former scheme) | 0108738 |
| P494 | ICD-10 ID | E61.1 |
| P7807 | ICD-11 ID (Foundation) | 362161517 |
| P7329 | ICD-11 ID (MMS) | 5B5K.0 |
| P493 | ICD-9 ID | 280.9 |
| P3827 | JSTOR topic ID (archived) | dietary-iron |
| P8313 | Lex ID | jernmangel |
| P3201 | Medical Dictionary for Regulatory Activities ID | 10022970 |
| 10022970 | ||
| P604 | MedlinePlus ID | 000584 |
| 000584 | ||
| P486 | MeSH descriptor ID | D000090463 |
| P672 | MeSH tree code | C18.452.565.400 |
| P691 | NL CR AUT ID | ph1154213 |
| P10283 | OpenAlex ID | C2777417653 |
| C3017702006 | ||
| P3417 | Quora topic ID | Iron-Deficiency-1 |
| P10376 | ScienceDirect topic ID | biochemistry-genetics-and-molecular-biology/iron-deficiency |
| food-science/iron-deficiency | ||
| nursing-and-health-professions/iron-deficiency | ||
| pharmacology-toxicology-and-pharmaceutical-science/iron-deficiency | ||
| P2892 | UMLS CUI | C0240066 |
| P11143 | WikiProjectMed ID | Iron deficiency |
| P1995 | health specialty | endocrinology | Q162606 |
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| Q67317600 | Increased dietary cadmium absorption in mice and human subjects with iron deficiency |
| Q67362344 | Indicators of iron metabolism in the body of patients with peptic ulcer after stomach resection |
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| Q44500855 | Iron Deficiency in the Rat: Biochemical Studies of Brain Metabolism |
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| Q37785029 | Iron Deficiency: Beyond Anemia |
| Q44420501 | Iron Depletion without Anemia Is Not Associated with Impaired Selenium Status in College-Aged Women |
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| Q48577914 | Sudden sensorineural hearing loss induced by experimental iron deficiency in rats |
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| Q72866378 | The effects of iron deficiency on brain biogenic monoamine biochemistry and function in rats |
| Q36130438 | The effects of iron deficiency on rat liver enzymes |
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| Q82137305 | The oral manifestations of iron deficiency |
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| Q67473309 | The relation of iron to blood platelets |
| Q66894914 | The relationship between infection and the iron status of an individual |
| Q67009401 | The role of plasma ferritin determination in screening for iron deficiency. Apropos of a study in 2 groups of children of different socioeconomic background |
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| Q1669835 | Ludwig Heilmeyer | field of work | P101 |
| uri / http://www.wikidata.org/entity/L502148-S1 | L502148-S1 | item for this sense | P5137 |
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