cholesterol biosynthetic process

The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.

cholesterol biosynthetic process is …
instance of (P31):
biological processQ2996394

sublass of (P279):
sterol biosynthetic processQ14599661
secondary alcohol biosynthetic processQ22274649
cholesterol metabolic processQ14599650

External links are
P2888exact matchhttp://purl.obolibrary.org/obo/GO_0006695
P686Gene Ontology IDGO:0006695
P2671Google Knowledge Graph ID/g/12233fd_
P2892UMLS CUIC0599474

P527has part(s)cholesterolQ43656

Reverse relations

regulates (molecular biology) (P128)
Q14890433negative regulation of cholesterol biosynthetic process
Q14889331positive regulation of cholesterol biosynthetic process
Q14890603regulation of cholesterol biosynthetic process

subclass of (P279)
Q21423011cholesterol biosynthetic process via 24,25-dihydrolanosterol
Q22282936cholesterol biosynthetic process via desmosterol
Q21209320cholesterol biosynthetic process via lathosterol

part of (P361)
Q271328454-methylzymosterol
Q43656cholesterol

biological process (P682)
Q42633424-dehydrocholesterol reductase
Q1459966524-dehydrocholesterol reductase
Q211410253-hydroxy-3-methylglutaryl coenzyme A reductase
Q4156073-hydroxy-3-methylglutaryl-CoA reductase
Q285620643-hydroxy-3-methylglutaryl-CoA reductase
Q211182933-hydroxy-3-methylglutaryl-CoA synthase 1
Q285581673-hydroxy-3-methylglutaryl-CoA synthase 1
Q211182843-hydroxy-3-methylglutaryl-CoA synthase 2
Q148641423-hydroxy-3-methylglutaryl-Coenzyme A reductase
Q214985683-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
Q214985653-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
Q616399913-hydroxy-3-methylglutaryl-coenzyme A reductase
Q149054577-dehydrocholesterol reductase
Q285607977-dehydrocholesterol reductase
Q2592927-dehydrocholesterol reductase
Q298238237-dehydrocholesterol reductase
Q551990847-dehydrocholesterol reductase
Q21105285ARV1 homolog, fatty acid homeostasis modulator
Q21096258ATP citrate lyase
Q21119315Acetyl-CoA acetyltransferase 2
Q28558396Acetyl-CoA acetyltransferase 2
Q21136257Acetyl-CoA acyltransferase 2
Q14910072Apolipoprotein A-I
Q21136986Apolipoprotein A-I, isoform CRA_a
Q21201272Apolipoprotein A-IV
Q21499492Apolipoprotein A-IV
Q29822762Apolipoprotein A-IV a
Q29823799Apolipoprotein A-IV b, tandem duplicate 1
Q29823666Apolipoprotein A-IV b, tandem duplicate 3
Q29823500Apolipoprotein A-Ib
Q21980338Apolipoprotein A-V
Q1316030Apolipoprotein A1
Q28560424Apolipoprotein A1
Q28558120Apolipoprotein A4
Q28559375Apolipoprotein A5
Q21416505Apolipoprotein E
Q28562617Apolipoprotein E
Q29827348Apolipoprotein Eb
Q24224251Blr5887
Q21111466CCHC-type zinc finger nucleic acid binding protein
Q55203695CF transmembrane conductance regulator
Q21114088Carboxylesterase 1
Q29518497Carboxylesterase 1A
Q21430297Carboxylesterase 1D
Q14864718Cystic fibrosis transmembrane conductance regulator
Q21985849Cytochrome b5 reductase 3
Q28562911Cytochrome b5 reductase 3
Q29798199DeHydroCholesterol Reductase CELE_B0250.9
Q21108560EBP cholestenol delta-isomerase
Q55200629EBP cholestenol delta-isomerase
Q28557862EBP, cholestenol delta-isomerase
Q21149489FDFT1 protein
Q21984837Farnesyl diphosphate farnesyl transferase 1
Q28557951Farnesyl diphosphate farnesyl transferase 1
Q28558088Farnesyl diphosphate synthase
Q21981997Farnesyl diphosphate synthetase
Q21108578Farnesyl-diphosphate farnesyltransferase 1
Q21106540Geranylgeranyl diphosphate synthase 1
Q28558145Glucose-6-phosphate dehydrogenase
Q421793Glucose-6-phosphate dehydrogenase
Q14877643Glucose-6-phosphate dehydrogenase X-linked
Q61563680HMG-CoA synthase
Q61637700HMG-CoA synthase
Q21497479Hydroxysteroid (17-beta) dehydrogenase 7
Q28560944Hydroxysteroid (17-beta) dehydrogenase 7
Q29828677Hydroxysteroid (17-beta) dehydrogenase 7
Q22680035Hydroxysteroid 17-beta dehydrogenase 7
Q21110728Insulin induced gene 1
Q21498638Insulin induced gene 1
Q21111115Insulin induced gene 2
Q21498639Insulin induced gene 2
Q28556018Insulin induced gene 2
Q55203843Insulin induced gene 2
Q21984319Isopentenyl-diphosphate delta isomerase
Q21151146Isopentenyl-diphosphate delta isomerase 1
Q28562497Isopentenyl-diphosphate delta isomerase 1
Q21132842Isopentenyl-diphosphate delta isomerase 2
Q21985476Isopentenyl-diphosphate delta isomerase 2
Q6481869Lamin B receptor
Q14911838Lamin B receptor
Q28562577Lamin B receptor
Q55204216Lamin B receptor
Q61493658Lamin B receptor (ERG24)
Q14912998Lanosterol synthase
Q28558787Lanosterol synthase
Q410833Lanosterol synthase
Q29822719Lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
Q21137667Methylsterol monooxygenase 1
Q21496618Mevalonate (diphospho) decarboxylase
Q29826347Mevalonate (diphospho) decarboxylase a
Q22676688Mevalonate diphosphate decarboxylase
Q28557827Mevalonate diphosphate decarboxylase
Q55201541Mevalonate diphosphate decarboxylase
Q29820385Mevalonate diphosphate decarboxylase Dmel_CG8239
Q14913013Mevalonate kinase
Q28558238Mevalonate kinase
Q424031Mevalonate kinase
Q29825156Mevalonate kinase
Q21121749NAD(P) dependent steroid dehydrogenase-like
Q21988845NAD(P) dependent steroid dehydrogenase-like
Q28559030NAD(P) dependent steroid dehydrogenase-like
Q903909NPC1 like intracellular cholesterol transporter 1
Q28563049NPC1 like intracellular cholesterol transporter 1
Q21496633Niemann-Pick C1-like protein 1
Q21984227Phenylalkylamine Ca2+ antagonist (emopamil) binding protein
Q21124331Phospholipid phosphatase 6
Q21989382Phosphomevalonate kinase
Q22676988Phosphomevalonate kinase
Q29523776Phosphomevalonate kinase
Q29822914Phosphomevalonate kinase
Q55205335Phosphomevalonate kinase
Q21115170Protein kinase AMP-activated catalytic subunit alpha 1
Q28563179Protein kinase AMP-activated catalytic subunit alpha 1
Q21115165Protein kinase AMP-activated catalytic subunit alpha 2
Q28561069Protein kinase AMP-activated catalytic subunit alpha 2
Q21498728Protein kinase, AMP-activated, alpha 1 catalytic subunit
Q21498733Protein kinase, AMP-activated, alpha 2 catalytic subunit
Q29825084Si:dkey-7f3.14
Q414248Squalene epoxidase
Q21105914Transmembrane 7 superfamily member 2
Q21495570Transmembrane 7 superfamily member 2
Q29519255Transmembrane 7 superfamily member 2
Q29817359Uncharacterized protein Dmel_CG10268
Q29812277Uncharacterized protein Dmel_CG33671
Q21173178apolipoprotein A5
Q420470cystic fibrosis transmembrane conductance regulator
Q21100886cytochrome P450 family 51 subfamily A member 1
Q21497411cytochrome P450, family 51
Q28556049cytochrome P450, family 51
Q21119544cytochrome b5 reductase 3
Q61597944dimethylallyltransferase
Q61640981diphosphomevalonate decarboxylase
Q62282008diphosphomevalonate decarboxylase
Q62316204diphosphomevalonate decarboxylase
Q21107439farnesyl diphosphate synthase
Q61512803farnesyl pyrophosphate synthase
Q61526565farnesyl pyrophosphate synthase
Q62179716farnesyl pyrophosphate synthase
Q62188539farnesyl pyrophosphate synthase
Q62216814farnesyl pyrophosphate synthase
Q62424550farnesyl pyrophosphate synthase
Q62441200farnesyl pyrophosphate synthase
Q62458713farnesyl pyrophosphate synthase
Q62144164farnesyl pyrophosphate synthase, putative
Q62153426farnesyl pyrophosphate synthase, putative
Q62189182farnesyl pyrophosphate synthase, putative
Q61555101phosphomevalonate kinase
Q62286443phosphomevalonate kinase
Q62312217phosphomevalonate kinase
Q62217944squalene synthase
Q62218970squalene synthase, putative
Q62430155squalene synthase, putative
Q62464476squalene synthase, putative

main subject (P921)
Q24300799Artemisinic acid inhibits melanogenesis through downregulation of C/EBP α-dependent expression of HMG-CoA reductase gene
Q24298050Cell growth and cholesterol metabolism in human glucose-6-phosphate dehydrogenase deficient lymphomononuclear cells
Q24319293Cloning and sequence analysis of a full length cDNA encoding human mitochondrial 3-oxoacyl-CoA thiolase
Q28114822Histidine77, glutamic acid81, glutamic acid123, threonine126, asparagine194, and tryptophan197 of the human emopamil binding protein are required for in vivo sterol delta 8-delta 7 isomerization
Q24316225Identification of a zinc finger protein that binds to the sterol regulatory element
Q24292898Molecular cloning of human mevalonate kinase and identification of a missense mutation in the genetic disease mevalonic aciduria
Q24321967Molecular cloning of human phosphomevalonate kinase and identification of a consensus peroxisomal targeting sequence

Q34340150Cholesterol biosynthesisinstance ofP31
Q39904823X-linked ichthyosis: A metabolic diseasecites workP2860

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