Beta-site APP-cleaving enzyme 2

mammalian protein found in Mus musculus

Wikidata entity: Q14865204



P682 biological process ... Q33123 (proteolysis) proteolysis
P682 biological process ... Q14859576 (amyloid-beta metabolic process) amyloid-beta metabolic process
P682 biological process ... Q14865200 (membrane protein ectodomain proteolysis) membrane protein ectodomain proteolysis
P682 biological process ... Q14865201 (negative regulation of amyloid precursor protein biosynthetic process) negative regulation of amyloid precursor protein biosynthetic process
P682 biological process ... Q14876077 (protein catabolic process) protein catabolic process
P682 biological process ... Q14758934 (glucose homeostasis) glucose homeostasis
P681 cell component ... Q29548 (plasma membrane) plasma membrane
P681 cell component ... Q79927 (endoplasmic reticulum) endoplasmic reticulum
P681 cell component ... Q83181 (Golgi apparatus) Golgi apparatus
P681 cell component ... Q189094 (cell surface) cell surface
P681 cell component ... Q824237 (endosome) endosome
P681 cell component ... Q14876714 (trans-Golgi network) trans-Golgi network
P681 cell component ... Q14907385 (dense core granule) dense core granule
P681 cell component ... Q14327652 (integral component of membrane) integral component of membrane
P681 cell component ... Q14349455 (membrane) membrane
P681 cell component ... Q79899 (cytoplasm) cytoplasm
P702 encoded by ... Q14865203 (Bace2) Bace2
P703 found in taxon ... Q83310 (house mouse) house mouse
P527 has part(s) ... Q24723211 (Peptidase family A1 domain) Peptidase family A1 domain
P527 has part(s) ... Q24788339 (Aspartic peptidase, active site) Aspartic peptidase, active site
P527 has part(s) ... Q27185344 (Memapsin-like) Memapsin-like
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q14859567 (aspartic-type endopeptidase activity) aspartic-type endopeptidase activity
P680 molecular function ... Q14890311 (amyloid-beta binding) amyloid-beta binding
P680 molecular function ... Q14353168 (hydrolase activity) hydrolase activity
P680 molecular function ... Q14645703 (peptidase activity) peptidase activity
P361 part of ... Q423042 (membrane protein) membrane protein
P361 part of ... Q24770369 (Beta-secretase BACE2) Beta-secretase BACE2
P361 part of ... Q24787484 (Aspartic peptidase domain superfamily) Aspartic peptidase domain superfamily
P361 part of ... Q83134222 (Peptidase family A1 domain) Peptidase family A1 domain
P361 part of ... Q83167028 (Memapsin-like, protein family) Memapsin-like, protein family
P361 part of ... Q95353019 (Aspartic peptidase, active site, protein family) Aspartic peptidase, active site, protein family

External Ids
P705Ensembl protein IDENSMUSP00000043918
P637RefSeq protein IDNP_062390
P637RefSeq protein IDXP_006523131
P352UniProt protein IDQ9JL18

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