Sclerostin

mammalian protein found in Mus musculus

Sclerostin is …
instance of (P31):
proteinQ8054

sublass of (P279):
proteinQ8054

External links are
P705Ensembl protein IDENSMUSP00000001534
P638PDB structure ID2KD3
P637RefSeq protein IDNP_077769
XP_006534439
P352UniProt protein IDQ99P68

P682biological processossificationQ1121544
Wnt signaling pathwayQ155769
positive regulation of transcription, DNA-templatedQ14818066
negative regulation of canonical Wnt signaling pathwayQ14860027
negative regulation of Wnt signaling pathwayQ14860186
negative regulation of ossificationQ14860506
negative regulation of BMP signaling pathwayQ14874551
negative regulation of protein-containing complex assemblyQ14887292
cellular response to parathyroid hormone stimulusQ14887293
negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specificationQ14887294
P681cell componentGolgi apparatusQ83181
extracellular spaceQ1385443
extracellular regionQ14645596
protein-containing complexQ22325163
P702encoded bySostQ14887296
P703found in taxonhouse mouseQ83310
P680molecular functionprotein bindingQ167149
transcription factor bindingQ14817982
heparin bindingQ14819453
P361part ofSclerostinQ24772538
Cystine-knot cytokineQ24783539

Reverse relations

main subject (P921)
Q28265558Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity
Q28592560Conditionals by inversion provide a universal method for the generation of conditional alleles
Q24630630FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis
Q28509512Genetic evidence that SOST inhibits WNT signaling in the limb
Q24300347Osteocyte control of bone formation via sclerostin, a novel BMP antagonist

Q14887296SostencodesP688