Caspase 8

mammalian protein found in Mus musculus

Wikidata entity: Q14911968



P682 biological process ... Q33123 (proteolysis) proteolysis
P682 biological process ... Q14599713 (response to tumor necrosis factor) response to tumor necrosis factor
P682 biological process ... Q14633911 (regulation of apoptotic process) regulation of apoptotic process
P682 biological process ... Q14818063 (positive regulation of apoptotic process) positive regulation of apoptotic process
P682 biological process ... Q14819884 (response to ethanol) response to ethanol
P682 biological process ... Q14860112 (neural tube formation) neural tube formation
P682 biological process ... Q14860513 (positive regulation of macrophage differentiation) positive regulation of macrophage differentiation
P682 biological process ... Q14860870 (activation of cysteine-type endopeptidase activity involved in apoptotic process) activation of cysteine-type endopeptidase activity involved in apoptotic process
P682 biological process ... Q14864035 (positive regulation of I-kappaB kinase/NF-kappaB signaling) positive regulation of I-kappaB kinase/NF-kappaB signaling
P682 biological process ... Q471817 (development of the heart) development of the heart
P682 biological process ... Q539568 (angiogenesis) angiogenesis
P682 biological process ... Q14599311 (apoptotic process) apoptotic process
P682 biological process ... Q14866099 (extrinsic apoptotic signaling pathway via death domain receptors) extrinsic apoptotic signaling pathway via death domain receptors
P682 biological process ... Q14866112 (apoptotic signaling pathway) apoptotic signaling pathway
P682 biological process ... Q14873901 (cardiac muscle tissue development) cardiac muscle tissue development
P682 biological process ... Q14877596 (positive regulation of extrinsic apoptotic signaling pathway) positive regulation of extrinsic apoptotic signaling pathway
P682 biological process ... Q14903307 (macrophage differentiation) macrophage differentiation
P682 biological process ... Q14903972 (extrinsic apoptotic signaling pathway) extrinsic apoptotic signaling pathway
P682 biological process ... Q14905475 (regulation of thymocyte apoptotic process) regulation of thymocyte apoptotic process
P682 biological process ... Q14905476 (regulation of apoptotic signaling pathway) regulation of apoptotic signaling pathway
P682 biological process ... Q14907134 (positive regulation of proteolysis) positive regulation of proteolysis
P682 biological process ... Q14907136 (activation of cysteine-type endopeptidase activity) activation of cysteine-type endopeptidase activity
P682 biological process ... Q14907291 (execution phase of apoptosis) execution phase of apoptosis
P682 biological process ... Q14907708 (positive regulation of neuron death) positive regulation of neuron death
P682 biological process ... Q14907899 (hepatocyte apoptotic process) hepatocyte apoptotic process
P682 biological process ... Q14911964 (proteolysis involved in cellular protein catabolic process) proteolysis involved in cellular protein catabolic process
P682 biological process ... Q21095682 (negative regulation of I-kappaB kinase/NF-kappaB signaling) negative regulation of I-kappaB kinase/NF-kappaB signaling
P682 biological process ... Q21100387 (TRAIL-activated apoptotic signaling pathway) TRAIL-activated apoptotic signaling pathway
P682 biological process ... Q21100389 (negative regulation of necroptotic process) negative regulation of necroptotic process
P681 cell component ... Q40260 (nucleus) nucleus
P681 cell component ... Q39572 (mitochondrion) mitochondrion
P681 cell component ... Q79899 (cytoplasm) cytoplasm
P681 cell component ... Q29548 (plasma membrane) plasma membrane
P681 cell component ... Q14645640 (neuron projection) neuron projection
P681 cell component ... Q220599 (cytosol) cytosol
P681 cell component ... Q424178 (membrane raft) membrane raft
P681 cell component ... Q14817956 (nucleoplasm) nucleoplasm
P681 cell component ... Q14864866 (cell body) cell body
P681 cell component ... Q5247052 (death-inducing signaling complex) death-inducing signaling complex
P681 cell component ... Q14907122 (CD95 death-inducing signaling complex) CD95 death-inducing signaling complex
P681 cell component ... Q14911962 (Noc1p-Noc2p complex) Noc1p-Noc2p complex
P681 cell component ... Q21100386 (ripoptosome) ripoptosome
P681 cell component ... Q22325163 (protein-containing complex) protein-containing complex
P702 encoded by ... Q14911966 (Casp8) Casp8
P2888 exact match Url UniProt ???
P2888 exact match Url UniProt ???
P2888 exact match Url None ???
P703 found in taxon ... Q83310 (house mouse) house mouse
P527 has part(s) ... Q24739412 (Peptidase C14, p20 domain) Peptidase C14, p20 domain
P527 has part(s) ... Q24769015 (Peptidase C14, caspase non-catalytic subunit p10) Peptidase C14, caspase non-catalytic subunit p10
P527 has part(s) ... Q24779591 (Peptidase family C14A, cysteine active site) Peptidase family C14A, cysteine active site
P527 has part(s) ... Q24780702 (Peptidase family C14A, His active site) Peptidase family C14A, His active site
P527 has part(s) ... Q24781095 (death effector domain) death effector domain
P527 has part(s) ... Q24784109 (Peptidase C14A, caspase catalytic domain) Peptidase C14A, caspase catalytic domain
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q167149 (protein binding) protein binding
P680 molecular function ... Q14633869 (ubiquitin protein ligase binding) ubiquitin protein ligase binding
P680 molecular function ... Q14645703 (peptidase activity) peptidase activity
P680 molecular function ... Q14762994 (identical protein binding) identical protein binding
P680 molecular function ... Q14762999 (protein heterodimerization activity) protein heterodimerization activity
P680 molecular function ... Q14861555 (endopeptidase activity) endopeptidase activity
P680 molecular function ... Q14864209 (scaffold protein binding) scaffold protein binding
P680 molecular function ... Q14864228 (cysteine-type endopeptidase activity) cysteine-type endopeptidase activity
P680 molecular function ... Q14864241 (cysteine-type peptidase activity) cysteine-type peptidase activity
P680 molecular function ... Q14353168 (hydrolase activity) hydrolase activity
P680 molecular function ... Q14866094 (tumor necrosis factor receptor binding) tumor necrosis factor receptor binding
P680 molecular function ... Q14905550 (death receptor binding) death receptor binding
P680 molecular function ... Q14911967 (cysteine-type endopeptidase activity involved in apoptotic process) cysteine-type endopeptidase activity involved in apoptotic process
P680 molecular function ... Q14914374 (cysteine-type endopeptidase activity involved in execution phase of apoptosis) cysteine-type endopeptidase activity involved in execution phase of apoptosis
P680 molecular function ... Q21100384 (death effector domain binding) death effector domain binding
P680 molecular function ... Q21100385 (cysteine-type endopeptidase activity involved in apoptotic signaling pathway) cysteine-type endopeptidase activity involved in apoptotic signaling pathway
P680 molecular function ... Q22312857 (protein-containing complex binding) protein-containing complex binding
P361 part of ... Q95350982 (Peptidase family C14A, cysteine active site, protein family) Peptidase family C14A, cysteine active site, protein family
P361 part of ... Q95353475 (Peptidase family C14A, His active site, protein family) Peptidase family C14A, His active site, protein family
P361 part of ... Q24724692 (caspase-like domain superfamily) caspase-like domain superfamily
P361 part of ... Q24776395 (Death-like domain superfamily) Death-like domain superfamily
P361 part of ... Q83136595 (Peptidase C14, p20 domain, protein family) Peptidase C14, p20 domain, protein family
P361 part of ... Q83138703 (Peptidase C14, caspase non-catalytic subunit p10, protein family) Peptidase C14, caspase non-catalytic subunit p10, protein family
P361 part of ... Q83147549 (Death effector domain, protein family) Death effector domain, protein family
P361 part of ... Q83163940 (Peptidase C14A, caspase catalytic domain, protein family) Peptidase C14A, caspase catalytic domain, protein family
P279 subclass of ... Q8054 (protein) protein

External Ids
P705Ensembl protein IDENSMUSP00000140546
P705Ensembl protein IDENSMUSP00000127375
P705Ensembl protein IDENSMUSP00000140335
P705Ensembl protein IDENSMUSP00000027189
P637RefSeq protein IDNP_001073595
P637RefSeq protein IDNP_001264855
P637RefSeq protein IDNP_033942
P637RefSeq protein IDXP_006495697
P637RefSeq protein IDXP_036012062
P352UniProt protein IDO89110

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