| Q57074437 | Q57074437 |
| Q101155349 | "Azole" as privileged heterocycle for targeting the inducible cyclooxygenase enzyme |
| Q56031121 | 17α-estradiol: a less-feminizing estrogen |
| Q86596685 | 5-HT2B Receptor Antagonists Reduce Nerve Injury-Induced Tactile Allodynia and Expression of 5-HT2B Receptors |
| Q36083177 | 8-(3-Isothiocyanatostyryl)caffeine Is a Selective, Irreversible Inhibitor of Striatal A(2)-Adenosine Receptors |
| Q92505080 | 8-Hydroxyquinolines are bactericidal against Mycobacterium tuberculosis |
| Q34955056 | A Discovery Funnel for Nucleic Acid Binding Drug Candidates |
| Q60218432 | A Hybrid Structure/Pharmacophore-Based Virtual Screening Approach to Design Potential Leads: A Computer-Aided Design of South African HIV-1 Subtype C Protease Inhibitors |
| Q38758615 | A New Role for an Old Drug: Metformin Targets MicroRNAs in Treating Diabetes and Cancer |
| Q57806448 | A brief appraisal of computational modeling of antimicrobial peptides' activity |
| Q92107770 | A comprehensive review of computational techniques for the prediction of drug side effects |
| Q63484472 | A major role for astrocytes in the neuroprotective effect of estrogen |
| Q57591357 | A new model for utilising chemical diversity from natural sources |
| Q93196895 | A new potential anti-cancer beta-carboline derivative decreases the expression levels of key proteins involved in glioma aggressiveness: A proteomic investigation |
| Q98383599 | A novel salvianolic acid A analog with resveratrol structure and its antioxidant activities in vitro and in vivo |
| Q98387346 | A novel series of substituted 1,2,3-triazoles as cancer stem cell inhibitors: Synthesis and biological evaluation |
| Q90743053 | A pharmacogenetic risk score for the evaluation of major depression severity under treatment with antidepressants |
| Q45111540 | A possible role of polycystic ovary syndrome for pregnancy complications in women with psoriasis |
| Q92511331 | A review of phenformin, metformin, and imeglimin |
| Q92770786 | A simple, robust, and affordable bioluminescent assay for drug discovery against infective African trypanosomes |
| Q38988896 | A synthetic biotinylated peptide, BP21, inhibits the induction of mRNA expression of inflammatory substances by oxidized- and lyso-phosphatidylcholine |
| Q52583829 | A variant of GRK5 is associated with the therapeutic efficacy of repaglinide in Chinese Han patients with type 2 diabetes mellitus. |
| Q58855805 | A1 adenosine receptor antagonists, 3-aryl[1,2,4]triazino[4,3-a]benzimidazol-4-(10H)-ones (ATBIs) andN-alkyl andN-acyl-(7-substituted-2-phenylimidazo[1,2-a][1,3,5]triazin-4-yl)amines (ITAs): Different recognition of bovine and human binding sites |
| Q91750595 | A3 Adenosine Receptors: Protective vs. Damaging Effects Identified Using Novel Agonists and Antagonists |
| Q60734912 | AG-4: a nicotinic agonist endowed with antiamnesic properties |
| Q61640396 | ATP release and effects in pancreas |
| Q60697604 | ATP release from the electric organ ofTorpedoand fromXenopusoocytes |
| Q57192034 | Actinomycin-D and dimethylamino-parthenolide synergism in treating human pancreatic cancer cells |
| Q36852764 | Actions of a Series of PPADS Analogs at P2X1 and P2X3 Receptors |
| Q36661011 | Activation and Desensitization of Rat A3-Adenosine Receptors by Selective Adenosine Derivatives and Xanthine-7-Ribosides |
| Q91845269 | Activation of Nrf2 signaling by sitagliptin and quercetin combination against β-amyloid induced Alzheimer's disease in rats |
| Q36330660 | Activation of Phosphoinositide Breakdown and Elevation of Intracellular Calcium in a Rat RBL-2H3 Mast Cell Line by Adenosine Analogs: Involvement of A(3)-Adenosine Receptors? |
| Q58212552 | Activation of the cAMP system by medorinone correlates with positive inotropy or vasorelaxation |
| Q38243627 | Activity cliff networks for medicinal chemistry |
| Q36086811 | Activity of Novel Adenine Nucleotide Derivatives as Agonists and Antagonists at Recombinant Rat P2X Receptors |
| Q70768515 | Acute and subchronic toxicity of thymoquinone in mice |
| Q112197434 | Adenosine (P1) receptor signalling |
| Q57405399 | Adenosine A1 receptors in rat brain synaptosomes: Transductional mechanisms, effects on glutamate release, and preservation after metabolic inhibition |
| Q57405391 | Adenosine A3 receptor agonist-induced neurotoxicity in rat cerebellar granule neurons |
| Q57405390 | Adenosine A3 receptors and viability of astrocytes |
| Q57567033 | Adenosine A3 receptors in the rat hippocampus: Lack of interaction with A1 receptors |
| Q63560640 | Adenosine deaminase-deficient mice as models for adenosine-mediated lung inflammation and damage |
| Q57567046 | Adenosine receptor interactions in the hippocampus |
| Q57405403 | Adenosine receptors in rat brain synaptosomes: Receptor characterization and relationships with glutamate release |
| Q60050345 | Adenosine-glutamate receptor-receptor interactions in the central nervous system |
| Q60050346 | Adenosine/dopamine receptor-receptor interactions in the central nervous system |
| Q60306109 | Advances in Computational Medicinal Chemistry: Matched Molecular Pair Analysis |
| Q57734363 | Advances in the genomics of allogeneic haemopoietic stem cell transplantation |
| Q39133502 | Advancing cancer patient care by integrating circulating tumor cell technology to understand the spatial and temporal dynamics of cancer |
| Q100508146 | Affinin and hexahydroaffinin: Chemistry and toxicological profile |
| Q104496858 | Alcohol intake potentiates clozapine adverse effects associated to CYP1A2*1C in patients with refractory psychosis |
| Q60644608 | Alcohol-induced reinforcement: Dopamine and 5-HT3 receptor interactions in animals and humans |
| Q57020448 | Alda-1, an aldehyde dehydrogenase-2 agonist, causes deterioration in renal functions following ischemia-reperfusion injury due to crystalline nephropathy |
| Q57257546 | Alfentanil (R 39 209) ? a particularly short-acting intravenous narcotic analgesic in rats |
| Q90798055 | Alignment-based design and synthesis of new antimicrobial Aurein-derived peptides with improved activity against Gram-negative bacteria and evaluation of their toxicity on human cells |
| Q100457394 | Allylphenols as a new class of human 15-lipoxygenase-1 inhibitors |
| Q36190899 | Alteration of Aging-Dependent MicroRNAs in Idiopathic Pulmonary Fibrosis |
| Q57074482 | Alzheimer's disease, estrogens, and clinical trials: a case study in drug development for complex disorders |
| Q89989899 | Alzheimer's disease: A need for personalized therapeutic approaches |
| Q102370630 | Ameliorative effect of a nano chromium metal-organic framework on experimental diabetic chronic kidney disease |
| Q98383641 | Amino acid conjugates of 2-mercaptobenzimidazole provide better anti-inflammatory pharmacology and improved toxicity profile |
| Q60645805 | Amiridine (NIK-247) and cerebrocrast in the alleviation of cholinergic lesion-induced learning deficit in male rats |
| Q61698679 | An active role for patients in clinical research? |
| Q53699027 | An investigation of the monoamine oxidase inhibition properties of pyrrolo[3,4-f]indole-5,7-dione and indole-5,6-dicarbonitrile derivatives. |
| Q96219897 | An outlook on procedures of conjugating folate to (co)polymers and drugs for effective cancer targeting |
| Q52309174 | An updated overview with simple and practical approach for developing in vitro-in vivo correlation. |
| Q39840852 | Analgesic Effect of the Newly Developed S(+)-Flurbiprofen Plaster on Inflammatory Pain in a Rat Adjuvant-Induced Arthritis Model |
| Q53685605 | Analgesic and anti-inflammatory activities of epicatechin gallate from Bauhinia hookeri. |
| Q47403687 | Analgesic and anti-inflammatory activities of the ethanol extract of Taxillus tsaii Chiu in mice |
| Q47247147 | Analgesic efficacy of preoperative dexketoprofen trometamol: A systematic review and meta-analysis. |
| Q60439573 | Analgesic efficacy of the combination metamizol+morphine after subchronic treatment in rats |
| Q94930122 | Androgen sensitivity gateway to COVID-19 disease severity |
| Q48169567 | Angelicin potentiates TRAIL-induced apoptosis in renal carcinoma Caki cells through activation of caspase 3 and down-regulation of c-FLIP expression |
| Q91860388 | Angiotensin II-induced micro RNA-21 culprit for non-small-cell lung adenocarcinoma |
| Q90027115 | Angiotensin receptor blockers as tentative SARS-CoV-2 therapeutics |
| Q91315216 | Anorectic efficacy and safety of the diethylpropion-topiramate combination in rats |
| Q105236502 | Anthrones, naturally occurring competitive inhibitors of adenosine-triphosphate-citrate lyase |
| Q48224511 | Anti-Inflammatory Effects of PEGylated Human Adrenomedullin in a Mouse DSS-Induced Colitis Model. |
| Q48121596 | Anti-Inflammatory and Analgesic Activities of Terminalia Muelleri Benth. (Combretaceae). |
| Q59358818 | Anti-Inflammatory and Antiproliferative Activities of Organic Fractions from the Mediterranean Brown Seaweed, Cystoseira Compressa |
| Q34069601 | Anti-Oligomannose Antibodies as Potential Serum Biomarkers of Aggressive Prostate Cancer |
| Q38995134 | Anti-inflammatory activities of melatonin derivatives in lipopolysaccharide-stimulated RAW 264.7 cells and antinociceptive effects in mice |
| Q48318439 | Anti-inflammatory and analgesic activities of cupressuflavone from Cupressus macrocarpa: Impact on pro-inflammatory mediators. |
| Q59119483 | Anti-inflammatory and antinociceptive effects of tilifodiolide, isolated from Salvia tiliifolia Vahl (Lamiaceae) |
| Q93056143 | Anti-inflammatory and diuretic effects of the diterpene ent-dihydrotucumanoic acid |
| Q93018364 | Anti-inflammatory effects of Vicenin-2 on dextran sulfate sodium-induced colitis in mice |
| Q91366316 | Anti-neuroinflammatory effects of tannic acid against lipopolysaccharide-induced BV2 microglial cells via inhibition of NF-κB activation |
| Q48360628 | Antiallodynic Activity of Ceftriaxone and Clavulanic Acid in Acute Administration is Associated with Serum TNF-α Modulation and Activation of Dopaminergic and Opioidergic Systems. |
| Q57054544 | Antiallodynic interaction and motor performance of the pregabalin/thioctic acid and pregabalin/α-tocopherol combinations in neonatal streptozotocin-induced diabetic rats |
| Q59242596 | Antiamnesic effect of the two novel ?-opioid agonists, VA-100 and VA-101, in the mouse passive avoidance test |
| Q53641686 | Antiarthritis Effect of Morin is Associated with Inhibition of Synovial Angiogensis. |
| Q102214609 | Antibacterial azole derivatives: Antibacterial activity, cytotoxicity, and in silico mechanistic studies |
| Q58108379 | Antibiotics as both friends and foes of the human gut microbiome: The microbial community approach |
| Q92170162 | Anticancer activity of newly synthesized 1,1-disubstituted cyclohexane-1-carboxamides: in vitro caspases mediated apoptosis activators in human cancer cell lines and their molecular modeling |
| Q91217791 | Anticonvulsant evaluation and docking analysis of VV-Hemorphin-5 analogues |
| Q38931373 | Antidepressant Action on Mitochondrial Dysfunction in Psychiatric Disorders. |
| Q38939488 | Antidiabetic Effect of Schisandrae Chinensis Fructus Involves Inhibition of the Sodium Glucose Cotransporter. |
| Q92170256 | Antidiarrheal, vasorelaxant, and neuropharmacological actions of the diterpene tilifodiolide |
| Q38700487 | Antiestrogenic Activity of Triptolide in Human Breast Cancer Cells MCF-7 and Immature Female Mouse. |
| Q50546387 | Antihyperalgesic Activity of Rhodiola rosea in a Diabetic Rat Model. |
| Q48127804 | Antihyperalgesic Effects of Indomethacin, Ketorolac, and Metamizole in Rats: Effects of Metformin. |
| Q46568863 | Antihyperglycemia and Antihyperlipidemia Effect of Protoberberine Alkaloids From Rhizoma Coptidis in HepG2 Cell and Diabetic KK-Ay Mice |
| Q104997961 | Antihypertensive activity of himbacine in anesthetized cats |
| Q57275725 | Antileishmanial Activity of Natural Product-Like Naphthoquinones |
| Q38497186 | Antimalarial Preclinical Drug Development: A Single Oral Dose of A 5-Carbon-linked Trioxane Dimer Plus Mefloquine Cures Malaria-Infected Mice |
| Q87278459 | Antimetastatic effects of gambogic acid are mediated via the actin cytoskeleton and NF-κB pathways in SK-HEP1 cells |
| Q47770129 | Antinociceptive Activity of Ent-Dihydrotucumanoic Acid Isolated from Gymnosperma glutinosum Spreng Less. |
| Q39173010 | Antinociceptive Activity of an Ethanol Extract of Justicia spicigera. |
| Q89317488 | Antinociceptive Effect of Racemic Flurbiprofen and Caffeine Co-Administration in an Arthritic Gout-Type Pain in Rats |
| Q89112621 | Antinociceptive Interactions Between Meloxicam and Gabapentin in Neuropathic Pain Depend on the Ratio used in Combination in Rats |
| Q46421363 | Antinociceptive and Antihyperalgesic Activity of a Traditional Maya Herbal Preparation Composed of Pouteria Campechiana, Chrysophyllum Cainito, Citrus Limonum, and Annona Muricata. |
| Q94566865 | Antinociceptive effects of ceftriaxone in formalin-induced nociception |
| Q59242598 | Antinociceptive profile of the natural cholinesterase inhibitor huperzine A |
| Q60735005 | Antinociceptive profile of the new nicotinic agonist DBO-83 |
| Q60735009 | Antinociceptive property of the nicotinic agonist AG-4 in rodents |
| Q91658157 | Antinociceptive, anti-inflammatory, and central nervous system (CNS) effects of the natural coumarin soulattrolide |
| Q86597157 | Antioxidant Activities of Caralluma tuberculata on Streptozotocin-Induced Diabetic Rats |
| Q48243994 | Antioxidant-mediated reversal of oxidative damage in mouse modeling of complex I inhibition. |
| Q100389174 | Antiparasitic activities of novel pyrimidine N-acylhydrazone hybrids |
| Q57033916 | Antiparasitic and immunomodulatory activities of 1,1-bis(4-hydroxyphenyl)-2-phenyl-but-1-ene and its protected and free 2-ferrocenyl derivatives |
| Q92107542 | Antiurolithiatic effects of pentacyclic triterpenes: The distance traveled from therapeutic aspects |
| Q57054547 | Antiviral compound screening, peptide designing, and protein network construction of influenza a virus (strain a/Puerto Rico/8/1934 H1N1) |
| Q92515995 | Antiviral effects of a niobium-substituted heteropolytungstate on hepatitis B virus-transgenic mice |
| Q51596222 | Apocynin Suppresses Lipopolysaccharide-Induced Inflammatory Responses Through the Inhibition of MAP Kinase Signaling Pathway in RAW264.7 Cells. |
| Q38783727 | Apoptotic Cell Death Induced by ofLBP6A, Lipopolysaccharide Binding Protein Model Peptide, Derived from Paralichthy olivaceus on MKN-28 Cells |
| Q38243626 | Application of chemometric techniques in search of clinically applicable biomarkers of disease |
| Q33901801 | Are CB(1) Receptor Antagonists Nootropic or Cognitive Impairing Agents? |
| Q58088048 | Are p53 inhibitors potentially useful therapeutics? |
| Q34622342 | Artemisinin Antimalarials: Preserving the "Magic Bullet" |
| Q56641839 | Artesunate Plus Amodiaquine Combination Therapy: Reviewing the Evidence |
| Q93026457 | Artesunate suppresses inflammation and oxidative stress in a rat model of colorectal cancer |
| Q62608678 | Artificial intelligence and outcome research |
| Q94561463 | Aspartate semialdehyde dehydrogenase inhibition suppresses the growth of the pathogenic fungus Candida albicans |
| Q38266318 | Assays and strategies for immunogenicity assessment of biological agents. |
| Q47191578 | Assessment of the antinociceptive and ulcerogenic activity of the tapentadol-diclofenac combination in rodents |
| Q95937928 | Association study between HTR2A rs6313 polymorphism and early response to risperidone and olanzapine in schizophrenia patients |
| Q91542980 | Autophagy induction in the treatment of Alzheimer's disease |
| Q91142563 | Aza-CGP37157-lipoic hybrids designed as novel Nrf2-inducers and antioxidants exert neuroprotection against oxidative stress and show neuroinflammation inhibitory properties |
| Q98647417 | Bacterial hepatocyte growth factor receptor agonist stimulates hepatocyte proliferation and accelerates liver regeneration in a partial hepatectomy rat model |
| Q35955377 | Baicalein Induces Caspase-dependent Apoptosis Associated with the Generation of ROS and the Activation of AMPK in Human Lung Carcinoma A549 Cells |
| Q102202488 | Barbiturate derivatives for managing multifaceted oncogenic pathways: A mini review |
| Q90476765 | Bedaquiline and delamanid in the treatment of multidrug-resistant tuberculosis: Promising but challenging |
| Q114865618 | Benefits and Limitations of Infrared Technologies in Omics Research and Development of Natural Drugs and Pharmaceutical Products |
| Q38939542 | Benefits of Cognitive Treatments Administered to Patients Affected by Mild Cognitive Impairment/Mild Neurocognitive Disorder |
| Q46500551 | Berberine Hydrochloride Protects C2C12 Myoblast Cells Against Oxidative Stress-Induced Damage via Induction of Nrf-2-Mediated HO-1 Expression |
| Q91592016 | Berberine inhibits the interleukin-1 beta-induced inflammatory response via MAPK downregulation in rat articular chondrocytes |
| Q101043299 | Bergenin inhibits bladder cancer progression via activating the PPARγ/PTEN/Akt signal pathway |
| Q37983058 | Beyond transitional selection: New roles for BLyS in peripheral tolerance |
| Q90628152 | Biocatalytic synthesis of diaryl disulphides and their bio-evaluation as potent inhibitors of drug-resistant Staphylococcus aureus |
| Q61773287 | Biochemical and behavioral studies of the 5-HT1B receptor agonist, CP-94,253 |
| Q51035615 | Biodistribution of the multidentate hydroxypyridinonate ligand [(14) C]-3,4,3-LI(1,2-HOPO), a potent actinide decorporation agent. |
| Q57838233 | Bioisosterism, enantioselectivity, and molecular modeling of new effective N6- and/or N(9)-substituted 2-phenyl adenines and 8-aza analogs: Different binding modes to A1 adenosine receptors |
| Q38979880 | Biological evaluation and SAR analysis of O-methylated analogs of quercetin as inhibitors of cancer cell proliferation |
| Q38243624 | Biological networks and drug discovery--where do we stand? |
| Q47671635 | Biomarkers for Major Depressive Disorder: Economic Considerations |
| Q104797777 | Biomarkers to predict staging and treatment response in opioid dependence: A narrative review |
| Q57074429 | Biomarkers-An Essential Tie That Binds the Future of Drugs and Diagnostics |
| Q41953858 | Bioprotective carnitinoids: lipoic acid, butyrate, and mitochondria-targeting to treat radiation injury: mitochondrial drugs come of age. |
| Q60060901 | Bradykinin-antagonists: Therapeutic perspectives |
| Q46075909 | Breaking Sad: Unleashing the Breakthrough Potential of Ketamine's Rapid Antidepressant Effects |
| Q57074450 | Bright lights, clearly visible in the healthcare R&D tunnel, could burn out for lack of funds |
| Q38197556 | Building the strategic national stockpile through the NIAID Radiation Nuclear Countermeasures Program |
| Q56961197 | Bupropion and thiothixene versus placebo and thiothixene in the treatment of depression in schizophrenia |
| Q122983850 | Butyrate prevents the migration and invasion, and aerobic glycolysis in gastric cancer via inhibiting Wnt/β‐catenin/c‐Myc signaling |
| Q102061680 | CB2 receptor-selective agonists as candidates for targeting infection, inflammation, and immunity in SARS-CoV-2 infections |
| Q56960032 | CNS response to a thermal stressor in human volunteers and rats may predict the clinical utility of analgesics |
| Q91054739 | CORRIGENDUM |
| Q91132522 | CORRIGENDUM |
| Q93202681 | COVID-19 transmission through host cell directed network of GPCR |
| Q90751923 | COVID-19 treatment by repurposing drugs until the vaccine is in sight |
| Q91285893 | Can acetaminophen/dimethyl sulfoxide formulation prevent accidental and intentional acetaminophen hepatotoxicity? |
| Q90709908 | Can light-based approaches overcome antimicrobial resistance? |
| Q44265857 | Cardiovascular risk in psoriatic patients detected by heart rate variability (HRV) analysis |
| Q85463354 | Carvedilol attenuates inflammatory biomarkers and oxidative stress in a rat model of ulcerative colitis |
| Q57074511 | Cell death as a life force |
| Q57074513 | Cell death as a life force |
| Q58376154 | Cell microarray platform for anticancer drug development |
| Q60735025 | Central muscarinic antinociception induced by ET-142 and SS-20 in rodents |
| Q92600037 | Cerebrolysin improves peripheral inflammatory pain: Sex differences in two models of acute and chronic mechanical hypersensitivity |
| Q41917137 | Characterization and Validation of a Canine Pruritic Model |
| Q96163478 | Characterization of a novel polymeric prodrug of an antibacterial agent synthesized by mechanochemical solid-state polymerization |
| Q60396203 | Characterization of indorenate effects on brain monoamine metabolism |
| Q57074656 | Cholinergic agents: Deficits in rat hippocampal choline acetyltransferase activity and spatial working memory induced by intracerebroventricular administration of stoichiometrically prepared 1-ethyl-1-(2-hydroxyethyl) aziridinium ion (AF64A) |
| Q115473919 | Cholinomimetic and anticholinergic drugs used to investigate an acetylcholine hypothesis of affective disorders and stress |
| Q90841944 | Chronic administration of Cl-amidine, a pan-peptidylarginine deiminase inhibitor, does not reverse bone loss in two different murine models of osteoporosis |
| Q114559891 | Click chemistry‐based synthesis of new benzenesulfonamide derivatives bearing triazole ring as selective carbonic anhydrase II inhibitors |
| Q35676177 | Clinical aspects of Chagas disease and implications for novel therapies |
| Q61669026 | Clinical experience with antithrombotic drugs acting on purine receptor pathways |
| Q85932898 | Clinical markers predictive of primary inefficacy: a "real life" retrospective study in psoriatic patients treated with etanercept |
| Q114389999 | Clobazam and diazepam: The differential effects on psychomotor performance and subjective feelings in normal volunteers with high neuroticism level |
| Q56337386 | Clonidine in mania |
| Q62107898 | Cloricromene conjugates with short-chain alkylamino acids: synthesis and biological evaluation |
| Q85849011 | Co-administration of N-Acetylcysteine and Acetaminophen Efficiently Blocks Acetaminophen Toxicity |
| Q85826166 | Coadministration of tramadol and tizanidine in an experimental acute pain model in rat |
| Q48332161 | Coenzyme Q10 Prevents the Interleukin-1 Beta Induced Inflammatory Response via Inhibition of MAPK Signaling Pathways in Rat Articular Chondrocytes. |
| Q91836850 | Cognitive dysfunction: A growing link between diabetes and Alzheimer's disease |
| Q46475564 | Combination of Vildagliptin and Pioglitazone in Experimental Type 2 Diabetes in Male Rats |
| Q103007648 | Combination of canstatin and arsenic trioxide suppresses the development of hepatocellular carcinoma |
| Q86043671 | Combination of diacerhein and antiepileptic drugs after local peripheral, and oral administration in the rat formalin test |
| Q99545850 | Combining kinase inhibitors for optimally co-targeting cancer and drug escape by exploitation of drug target promiscuities |
| Q56554959 | Comparative pharmacology of dothiepin, its metabolites, and other antidepressant drugs |
| Q34771848 | Comparison of antidepressant-like and abuse-related effects of phencyclidine in rats |
| Q57074568 | Comparison of the proteolytic susceptibilities of homologous L-amino acid, D-amino acid, and N-substituted glycine peptide and peptoid oligomers |
| Q48333924 | Computational and experimental exploration of the structure-activity relationships of flavonoids as potent glyoxalase-I inhibitors. |
| Q30366521 | Computational approaches for drug discovery. |
| Q60689036 | Conotoxins and their potential pharmaceutical applications |
| Q56141873 | Consequences of eliminating adenosine A1receptors in mice |
| Q34162960 | Correcting transcription factor gene sets for copy number and promoter methylation variations |
| Q126592013 | Cover Image, Volume 80, Issue 8 |
| Q92297331 | Cristazine, a novel dioxopiperazine alkaloid, induces apoptosis via the death receptor pathway in A431 cells |
| Q104503321 | Cryptotanshinone ameliorates cardiac injury and cardiomyocyte apoptosis in rats with coronary microembolization |
| Q91592138 | Curcumin ameliorates experimental autoimmune encephalomyelitis in a C57BL/6 mouse model |
| Q38959069 | Curcumin inhibits the proliferation and invasiveness of MHCC97-H cells via p38 signaling pathway |
| Q92558817 | Curcumin mitigates the epithelial-to-mesenchymal transition in biliary epithelial cells through upregulating CD109 expression |
| Q91137958 | Curcumin reduces inflammation in knee osteoarthritis rats through blocking TLR4 /MyD88/NF-κB signal pathway |
| Q97888332 | Curcumol improves cisplatin sensitivity of human gastric cancer cells through inhibiting PI3K/AKT pathway |
| Q57208363 | Cyclodextrin complexes: Perspective from drug delivery and formulation |
| Q90705102 | D-ribose-L-cysteine enhances memory task, attenuates oxidative stress and acetyl-cholinesterase activity in scopolamine amnesic mice |
| Q86597375 | Dalbergia odorifera Extract Ameliorates UVB-Induced Wrinkle Formation by Modulating Expression of Extracellular Matrix Proteins |
| Q85932929 | Decrease of asymmetric dimethyl arginine after anti-TNF therapy in patients with rheumatoid arthritis |
| Q38933518 | Delivery of Antipsychotics with Nanoparticles |
| Q92560746 | Design and synthesis of 2-hydroxyl-4-methoxyl-3-(3-methylbut-2-en-1-yl)-6-(4-phenylbenzoylamino)benzoic acid derivatives as antibacterial agents based on cajaninstilbene acid scaffold hopping |
| Q93381873 | Design and synthesis of simplified speciophylline analogues and β-carbolines as active molecules against Plasmodium falciparum |
| Q103827168 | Design of multicomponent indomethacin-paracetamol and famotidine loaded nanoparticles for sustained and effective anti-inflammatory therapy |
| Q91657904 | Design, graph theoretical analysis, density functionality theories, Insilico modeling, synthesis, characterization and biological activities of novel thiazole fused quinazolinone derivatives |
| Q98242583 | Design, synthesis and biological evaluation of several aromatic substituted chalcones as antimalarial agents |
| Q91759353 | Design, synthesis, and antifungal activity of novel cinnamon-pyrazole carboxamide derivatives |
| Q92519724 | Design, synthesis, and biological activity evaluation of BACE1 inhibitors with antioxidant activity |
| Q90664769 | Design, synthesis, and biological evaluation of 1,8-naphthyridine glucosamine conjugates as antimicrobial agents |
| Q58079805 | Design, synthesis, and biological evaluation of Helicobacter pylori inosine 5'-monophosphate dehydrogenase (HpIMPDH) inhibitors |
| Q104797779 | Design, synthesis, and structure-activity relationship study of O-prenylated 3-acetylcoumarins as potent inhibitors of soybean 15-lipoxygenase |
| Q104503258 | Design, synthesis, in vitro and in silico studies of novel Schiff base derivatives of 2-hydroxy-4-methoxybenzamide as tyrosinase inhibitors |
| Q104745737 | Design, synthesis, molecular docking, anti-quorum sensing, and anti-biofilm activity of pyochelin-zingerone conjugate |
| Q102214659 | Designing therapeutic strategies to combat severe acute respiratory syndrome coronavirus-2 disease: COVID-19 |
| Q57342839 | Destination Known: Targeted Drug Delivery in Atherosclerosis and Thrombosis |
| Q48060378 | Detection of adalimumab and anti-adalimumab levels by ELISA: clinical considerations. |
| Q57220707 | Detection of apoptosis-associated DNA fragmentation using a rapid and quantitative filter elution assay |
| Q57026358 | Determination of permeability, plasma protein binding, blood partitioning, pharmacokinetics and tissue distribution of Withanolide A in rats: A neuroprotective steroidal lactone |
| Q92770770 | Development and characterization of oxaceprol-loaded poly-lactide-co-glycolide nanoparticles for the treatment of osteoarthritis |
| Q60325187 | Development of a pharmacological target profile for muscarinic agonists |
| Q56874687 | Dexanabinol (HU-211): A nonpsychotropic cannabinoid with neuroprotective properties |
| Q57074572 | Diagnosing the decline of major pharmaceutical research laboratories: A prescription for drug companies |
| Q90403965 | Differential regulation of intestinal and hepatic CYP3A by 1α,25-dihydroxyvitamin D3 : Effects on in vivo oral absorption and disposition of buspirone in rats |
| Q57744979 | Differential up-regulation of D-1 and D-2 dopamine receptor function in mesostriatal areas but not in cortical-limbic brain regions of rats chronically treated with (?)sulpiride and SCH 23390 |
| Q91845306 | Dimethylaminoparthenolide reduces the incidence of dysplasia and ameliorates a wasting syndrome in HPV16-transgenic mice |
| Q42731763 | Discovering Molecular Targets in Cancer with Multiscale Modeling |
| Q96437285 | Discovery and Characterization of Novel Naphthalimide Analogs as Potent Multitargeted Directed Ligands against Alzheimer's Disease |
| Q57912132 | Discovery and investigation of lead compounds as binders to the Extra-Domain B of the angiogenesis marker, fibronectin |
| Q92806637 | Discovery of a new family of heterocyclic amine linked plastoquinone analogs for antimicrobial evaluation |
| Q92770779 | Discovery of a novel fluorescent chemical probe suitable for evaluation of neuropilin-1 binding of small molecules |
| Q93114144 | Discovery of natural naphthoquinones as sortase A inhibitors and potential anti-infective solutions against Staphylococcus aureus |
| Q90740995 | Discovery of novel halogenated 8-hydroxyquinoline-based anti-MRSA agents: In vitro and QSAR studies |
| Q57348773 | Discrete thermally responsive hydrogel-coated gold nanoparticles for use as drug-delivery vehicles |
| Q57272486 | Dissecting the apoptotic mechanisms of chemotherapeutic drugs and lymphocytes to design effective anticancer therapies |
| Q39338486 | Do Circadian Rhythms Draw the Patterns of Sustained Mental Vigor and Ailment? |
| Q38572889 | Does miRNA-155 Promote Cyclooxygenase-2 Expression in Cancer? |
| Q57806452 | Dose translation between laboratory animals and human in preclinical and clinical phases of drug development |
| Q91948176 | Dose-dependent chemopreventive effects of citronellol in DMBA-induced breast cancer among rats |
| Q114389996 | Double-blind placebo-controlled study of the autonomic effects of clovoxamine, imipramine, and amitriptyline in normal volunteers |
| Q57453066 | Drug development and bioanalytical method validation for a novel anticancer molecule, 4-(dimethylamino)-2-(p-tolylamino) thiazole-5-carbonitrile |
| Q125816473 | Drug development and research in New Zealand: policies affecting the industry |
| Q101155452 | Drug encapsulating polysaccharide-loaded metal nanoparticles: A perspective drug delivery system |
| Q57470807 | Drug resistance in Mycobacterium tuberculosis and targeting the l,d-transpeptidase enzyme |
| Q93031110 | Drug sales confirm clinical advantage of multi-target inhibition of drug escapes by anticancer kinase inhibitors |
| Q59383487 | DuP 996 (3,3-bis(4-pyrindinylmethyl)-1-phenylindolin-2-one) enhances the stimulus-induced release of acetylcholine from rat brain in vitro and in vivo |
| Q60357254 | Dual effect of a new compound, rupatadine, on edema induced by platelet‐activating factor and histamine in dogs: Comparison with antihistamines and PAF antagonists |
| Q91975537 | Dual targeting of cholinesterase and amyloid beta with pyridinium/isoquinolium derivatives |
| Q37240726 | EGFR Inhibition in the Treatment of Non-Small Cell Lung Cancer |
| Q101479062 | ERRATUM |
| Q87417860 | Early, middle, or late administration of zoledronate alleviates spontaneous nociceptive behavior and restores functional outcomes in a mouse model of CFA-induced arthritis |
| Q60050348 | Ecto-adenosine deaminase: An ecto-enzyme and a costimulatory protein acting on a variety of cell surface receptors |
| Q57074581 | Editorial |
| Q91983436 | Effect of IS01957, a para-coumaric acid derivative on pharmacokinetic modulation of diclofenac through oral route for augmented efficacy |
| Q93358549 | Effect of Syringic acid on antioxidant biomarkers and associated inflammatory markers in mice model of asthma |
| Q114389993 | Effect of a novel monamine oxidase-a inhibitor, bw 1370U87, on urinary 3-methoxy-4-hydroxyphenylglycol in normal volunteers |
| Q90021301 | Effect of age and renal impairment on the pharmacokinetics and safety of trimetazidine: An open-label multiple-dose study |
| Q87267969 | Effect of α-Hederin on IL-2 and IL-17 mRNA and miRNA-133a Levels in Lungs of Ovalbumin-Sensitized Male Rats |
| Q59649334 | Effectiveness and outcome research studies: current trends |
| Q91845336 | Effectiveness of nalbuphine, a κ-opioid receptor agonist and μ-opioid receptor antagonist, in the inhibition of INa , IK(M) , and IK(erg) unlinked to interaction with opioid receptors |
| Q38955608 | Effects of Intranasal Oxytocin on Long-Term Memory in Healthy Humans: A Systematic Review. |
| Q60678460 | Effects of ReN1869, a CNS-available antihistamine, on capsaicin- and histamine-induced neurogenic inflammation in healthy subjects |
| Q46643381 | Effects of TNF-alpha inhibitors on circulating Th17 cells in patients affected by severe psoriasis |
| Q33733502 | Effects of acute and sustained pain manipulations on performance in a visual-signal detection task of attention in rats |
| Q90107855 | Effects of different doses of atorvastatin, rosuvastatin, and simvastatin on elderly patients with ST-elevation acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI) |
| Q115201499 | Effects of epidermal growth factor in the mammalian central nervous system: Its possible implications in brain pathologies and therapeutic applications |
| Q85463350 | Effects of kramecyne on LPS induced chronic inflammation and gastric ulcers |
| Q61439992 | Effects of linopirdine (DuP 996) and X9121 on age-related memory impairments and on the cholinergic system |
| Q62961731 | Effects of nicotinic cholinergic agents on cognitive functioning in Alzheimer's and Parkinson's disease |
| Q100418318 | Effects of sinomenine on the proliferation, cytokine production, and regulatory T-cell frequency in peripheral blood mononuclear cells of rheumatoid arthritis patients |
| Q87278038 | Effects of the inhalation of the m3 receptor antagonist bencycloquidium bromide in a mouse cigarette smoke-induced airway inflammation model |
| Q114390000 | Effects of viloxazine with and without alcohol on performance tests related to driving in normal volunteers |
| Q92186840 | Efficacy of a phenol derivative, isopropyl vanillate, as an anti-inflammatory agent: A new small molecule inhibitor of COX and neutrophil migration |
| Q92555145 | Efficacy of targeted liposomes and nanocochleates containing imatinib plus dexketoprofen against fibrosarcoma |
| Q38266321 | Emergence of antinuclear antibodies in psoriatic patients treated with infliximab: personal experience and literature review |
| Q91682794 | Emerging role of primary heterogeneous nucleation in pharmaceutical crystallization |
| Q56520294 | Endocrine effects of dehydroepiandrosterone and its fluorinated analog, fluasterone, in rats |
| Q85664353 | Enhancement of Antihyperalgesia by the Coadministration of N-palmitoylethanolamide and Acetaminophen in Diabetic Rats |
| Q34172202 | Ensemble Classification of Cancer Types and Biomarker Identification |
| Q98281646 | Epigallocatechin gallate and theaflavin gallate interaction in SARS-CoV-2 spike-protein central channel with reference to the hydroxychloroquine interaction: Bioinformatics and molecular docking study |
| Q38946328 | Epigenetic Mechanisms in Psychiatric Diseases and Epigenetic Therapy |
| Q38742951 | Epigenetic Treatment of Neurodegenerative Disorders: Alzheimer and Parkinson Diseases |
| Q38743021 | Epigenetic Treatment of Neuropsychiatric Disorders: Autism and Schizophrenia. |
| Q38985869 | Epigenetic Treatment of Persistent Viral Infections. |
| Q85263415 | Epigenomic networking in drug development: from pathogenic mechanisms to pharmacogenomics |
| Q89624645 | Erratum |
| Q62123225 | Estradiol-induced enhancement in cell proliferation is mediated through estrogen receptors in the dentate gyrus of adult female rats |
| Q57074489 | Estrogens and Neuroprotection: desperate housewives, lost, and survivor |
| Q57074492 | Ethical Issues in the Biotechnology and Pharmaceutical Industries |
| Q43866638 | Evaluating the toxicity of novel Zn-DTPA tablet formulation in dogs and rats. |
| Q36470177 | Evaluation of a Postoperative Pain-Like State on Motivated Behavior in Rats: Effects of Plantar Incision on Progressive-Ratio Food-Maintained Responding |
| Q100429003 | Evaluation of hyaluronic acid nanoparticle embedded chitosan-gelatin hydrogels for antibiotic release |
| Q89493781 | Evaluation of oral pharmacokinetics, in vitro metabolism, blood partitioning and plasma protein binding of novel antidiabetic agent, S009-0629 in rats |
| Q64860741 | Evaluation of phytomedicinal potential of perillyl alcohol in an in vitro Parkinson's Disease model |
| Q91315224 | Evaluation of samidorphan, a μ-opioid antagonist, in a drug discrimination assay in rats |
| Q90237753 | Evaluation of selected commercial pharmacotherapeutic drugs as potential pancreatic lipase inhibitors and antiproliferative compounds |
| Q35941004 | Evaluation of the Oral Bioavailability of Low Molecular Weight Heparin Formulated With Glycyrrhetinic Acid as Permeation Enhancer |
| Q90385841 | Evaluation of the neuropharmacological effects of Gardenin A in mice |
| Q101211286 | Evaluation of the oral administration of α-l-guluronic acid on COX-1 and COX-2 gene expression profile in ankylosing spondylitis patients |
| Q57074444 | Evaluation of the pKa values and ionization sequence of bumetanide using 1H and 13C NMR and UV spectroscopy |
| Q36343279 | Evidence for the Recognition of Non-Nucleotide Antagonists Within the Transmembrane Domains of the Human P2Y(1) Receptor |
| Q57899044 | Evidence-based medicine in migraine prophylactic treatment in childhood and adolescence |
| Q52150640 | Exosomal MicroRNAs in Tissue Crosstalk. |
| Q59644201 | Exploring the normal regulation of fetal-placental calcium metabolism through the use of targeted gene ablation in fetal mice |
| Q61783472 | Expression and characerization of human kainate receptor subunits inEscherichia coli and mammalian cells |
| Q121789554 | FAM64A aggravates proliferation, invasion, lipid droplet formation, and chemoresistance in gastric cancer: A biomarker for aggressiveness and a gene therapy target |
| Q51748893 | FR-190997, a nonpeptide bradykinin B2-receptor partial agonist, is a potent and efficacious intraocular pressure lowering agent in ocular hypertensive cynomolgus monkeys. |
| Q102330154 | Fenofibrate attenuates ischemia reperfusion-induced acute kidney injury and associated liver dysfunction in rats |
| Q57708559 | Flavonoids - novel lead compounds for the development of P2Y2receptor antagonists |
| Q96433806 | Flufenamic acid alleviates sepsis-induced lung injury by up-regulating CBR1 |
| Q92368275 | Folic acid functionalized nanoparticles as pharmaceutical carriers in drug delivery systems |
| Q91545669 | Folic acid-conjugated raloxifene hydrochloride carbon nanotube for targeting breast cancer cells |
| Q60691053 | Foreword |
| Q40562632 | Fosinopril Prevents the Development of Tactile Allodynia in a Streptozotocin-Induced Diabetic Rat Model |
| Q47591876 | Free fatty acid receptor 1 agonist, MR1704, lowers blood glucose levels in rats unresponsive to the sulfonylurea, glibenclamide. |
| Q30490232 | From Gutenberg to Open Science: An Unfulfilled Odyssey |
| Q57074553 | From genes to drugs: Better, faster, cheaper |
| Q64938980 | From transcriptomics to biological networks. |
| Q36139676 | Fucoidan Induces ROS-Dependent Apoptosis in 5637 Human Bladder Cancer Cells by Downregulating Telomerase Activity via Inactivation of the PI3K/Akt Signaling Pathway |
| Q58610023 | Functional mechanism of tracheal relaxation, antiasthmatic, and toxicological studies of 6-hydroxyflavone |
| Q90012556 | Further modifications of 1H-pyrrolo[2,3-b]pyridine derivatives as inhibitors of human neutrophil elastase |
| Q60695443 | Gastrointestinal-sparing anti-inflammatory drugs: The development of nitric oxide-releasing NSAIDs |
| Q48117365 | Gastroprotective effect of calealactone B: Lack of involvement of prostaglandins, nitric oxide and sulfhydryls. |
| Q35626348 | Gastroprotective properties of cashew gum, a complex heteropolysaccharide of Anacardium occidentale, in naproxen-induced gastrointestinal damage in rats. |
| Q90339446 | Genetic determinants of circulating VEGF levels in major depressive disorder and electroconvulsive therapy response |
| Q38246625 | Genetic findings in obsessive-compulsive disorder connect to brain-derived neutrophic factor and mammalian target of rapamycin pathways: implications for drug development |
| Q99213167 | Ginsenoside Rg3 attenuates ovariectomy-induced osteoporosis via AMPK/mTOR signaling pathway |
| Q53687072 | Giving priority to preclinical pain measures resistant to existing drugs for developing innovative analgesics. |
| Q92647563 | Glycitein induces reactive oxygen species-dependent apoptosis and G0/G1 cell cycle arrest through the MAPK/STAT3/NF-κB pathway in human gastric cancer cells |
| Q90880945 | Graph theoretical analysis, in silico modeling, prediction of toxicity, metabolism and synthesis of novel 2-(methyl/phenyl)-3-(4-(5-substituted-1,3,4-oxadiazol-2-yl) phenyl) quinazolin-4(3H)-ones as NMDA receptor inhibitor |
| Q91752225 | Harnessing snake venom phospholipases A2 to novel approaches for overcoming antibiotic resistance |
| Q105173556 | Hepatoprotective effect of an active constituent isolated from the leaves ofRicinus communis Linn |
| Q48121669 | Herbal Formula, Baogan Yihao (BGYH), Prevented Dimethylnitrosamine(DMN)-Induced Liver Injury in Rats. |
| Q48057538 | High Dosage of Vitamin D Regulates the Energy Metabolism and Increases Insulin Sensitivity, but are Associated with High Levels of Kidney Damage |
| Q62395629 | Hippocampal structure and the action of cholinomimetic drugs |
| Q104510483 | Hirudin prevents vascular endothelial cell apoptosis and permeability enhancement induced by the serum from rat with chronic renal failure through inhibiting RhoA/ROCK signaling pathway |
| Q60414880 | Hormonal mediation of the memory disorder in depression |
| Q57995824 | Human Apolipoprotein E concentration in response to diseases and therapeutic treatments |
| Q96649079 | Hybrid molecules based on 1,3,5-triazine as potential therapeutics: A focused review |
| Q57239716 | Hydrophobic derivatives of 5-(hydroxymethyl)isophthalic acid that selectively induce apoptosis in leukemia cells but not in fibroblasts |
| Q85932933 | Hyperuricemia in patients with chronic plaque psoriasis |
| Q38296553 | INTEGRATING COMPUTATIONAL PROTEIN FUNCTION PREDICTION INTO DRUG DISCOVERY INITIATIVES. |
| Q57405378 | Identification of a novel P2 receptor associated with cyclooxygenase-2 upregulation and reactive astrogliosis |
| Q91722985 | Identification of embelin, a 3-undecyl-1,4-benzoquinone from Embelia ribes as a multitargeted anti-Alzheimer agent |
| Q33712786 | Identification of novel cellular targets for therapeutic intervention against Ebola virus infection by siRNA screening |
| Q92241193 | Identification of two arylimides as cholinesterase inhibitors and testing of propranolol addition on impaired rat memory |
| Q91575299 | Ilexgenin A inhibits mitochondrial fission and promote Drp1 degradation by Nrf2-induced PSMB5 in endothelial cells |
| Q91054766 | Immunopharmacological effect of β-d-mannuronic acid (M2000), as a new immunosuppressive drug, on gene expression of miR-155 and its target molecules (SOCS1, SHIP1) in a clinical trial on rheumatoid arthritis patients |
| Q34624834 | Immunoregulatory and Effector Activities in Human Cutaneous and Mucosal Leishmaniasis: Understanding Mechanisms of Pathology |
| Q38572855 | Impact of Histone Deacetylase Inhibitors on microRNA Expression and Cancer Therapy: A Review |
| Q63560635 | Impact of endogenous adenosine on airway hyperreactivity |
| Q90678877 | Impelling TLR9: Road to perspective vaccine for visceral leishmaniasis |
| Q60734948 | Improvement of cognitive functions by the acetylcholine releaser SM 21 |
| Q38955513 | Improving Current Treatments for Schizophrenia |
| Q34908616 | In Silico Augmentation of the Drug Development Pipeline: Examples from the study of Acute Inflammation. |
| Q89493778 | In silico and in vivo investigation of ferrocene-incorporated acyl ureas and homoleptic cadmium carboxylate derivatives for anticonvulsant, anxiolytic, and sedative potential |
| Q104745756 | In silico design and synthesis of N-arylalkanyl 2-naphthamides as a new class of non-purine xanthine oxidase inhibitors |
| Q54484162 | In silico prediction of cytochrome P450 inhibitors |
| Q57980309 | In silico subtractive genomics for target identification in human bacterial pathogens |
| Q90588475 | In vitro and in vivo evaluation of radiolabeled methyl N-[5-(3'-halobenzoyl)-1H-benzimidazol-2-yl]carbamate for cancer radiotherapy |
| Q94486029 | In vitro-in vivo evaluation of tetrahydrozoline-loaded ocular in situ gels on rabbits for allergic conjunctivitis management |
| Q94486019 | In vivo pharmacokinetic study and oral glucose tolerance test of sulfoxide analogs of GPR40 agonist TAK-875 |
| Q41244382 | In vivo wound-healing effects of novel benzalkonium chloride-loaded hydrocolloid wound dressing |
| Q57020445 | In-house chemical library repurposing: A case example for Pseudomonas aeruginosa antibiofilm activity and quorum sensing inhibition |
| Q97430727 | Increasing engagement in pharmacology and pharmacogenetics education using games and online resources: The PharmacoloGenius mobile app |
| Q57697486 | Informing resource allocation decision making: economic evaluations of pharmacogenetic tests |
| Q57806453 | Inhibiting conjugation as a tool in the fight against antibiotic resistance |
| Q36852770 | Inhibition of Ecto-Apyrase and Ecto-ATPase by Pyridoxal Phosphate-Related Compounds |
| Q38939321 | Inhibition of LPS-induced TLR4 signaling products in murine macrophages by phenylmethimazole: an assay methodology for screening potential phenylmethimazole analogs |
| Q60583269 | Inhibition of NF-kB/DNA Interactions and HIV-1 LTR Directed Transcription by Hybrid Molecules Containing Pyrrolo [2,1-c] [1,4] Benzodiazepine (PBD) and Oligopyrrole Carriers |
| Q56690406 | Inhibition of Na,K-ATPase activity and ouabain binding by sanguinarine |
| Q90996698 | Inhibition of angiogenesis and tumor growth by a novel 1,4-naphthoquinone derivative |
| Q59577286 | Insights on the Role of Physical Activity in Patients with Rheumatoid Arthritis |
| Q89542342 | Insulin resistance and impaired lipid metabolism as a potential link between diabetes and Alzheimer's disease |
| Q33983773 | Integrin alpha(v)beta(3)-Targeted Cancer Therapy |
| Q57405372 | Intracellular phosphorylation of chloro-adenosine analogs is a prerequisite for activation of caspase-3 and induction of apoptosis in human astrocytoma cells |
| Q38243630 | Introduction to RNA-Seq and its applications to drug discovery and development |
| Q57074530 | Introduction to mitochondrial function and genomics |
| Q92316249 | Investigation of a new horizon antifungal activity with enhancing the antimicrobial efficacy of ciprofloxacin and its binary mixture via their encapsulation in nanoassemblies: in vitro and in vivo evaluation |
| Q97540234 | Investigation of antioxidant and anti-nociceptive potential of isoxazolone, pyrazolone derivatives, and their molecular docking studies |
| Q90881095 | Investigation of the antibacterial and antifungal activity of thiolated naphthoquinones |
| Q57026355 | Investigation of the antimicrobial and anticancer activity of aminonaphthoquinones |
| Q92585526 | Involvement of l-arginine-nitric oxide pathway in the antidepressant and memory promoting effects of morin in mice |
| Q88177542 | Involvement of nitric oxide and ATP-sensitive potassium channels in the peripheral antinoceptive action of a tramadol-dexketoprofen combination in the formalin test |
| Q60439566 | Involvement of serotonin mechanisms in the antinociceptive effect of S(+)-ketoprofen |
| Q47881378 | Is 2-Hydroxypropyl-β-cyclodextrin a Suitable Carrier for Central Administration of Δ9 -Tetrahydrocannabinol? Preclinical Evidence |
| Q38859610 | Isobolographic Analyses of Proglumide-Celecoxib Interaction in Rats with Painful Diabetic Neuropathy |
| Q39774013 | Isobolographic Analysis of the Interaction Between Tapentadol and Ketorolac in a Mouse Model of Visceral Pain. |
| Q53161437 | Isorhamnetin-3-O-Glucuronide Suppresses JNK and p38 Activation and Increases Heme-Oxygenase-1 in Lipopolysaccharide-Challenged RAW264.7 Cells. |
| Q38266317 | Killer-cell immunoglobulin-like receptors (KIR) and HLA-class I heavy chains in ankylosing spondylitis. |
| Q60054758 | L-683,877: Pharmacological profile of a novel 5-HT3 receptor antagonist |
| Q91142520 | L6H9 attenuates LPS-induced acute lung injury in rats through targeting MD2 |
| Q91054826 | Leukocyte telomere length is reduced in patients with major depressive disorder |
| Q34412157 | Ligand Binding Sensitivity of the Extracellular Loop Two of the Cannabinoid Receptor 1. |
| Q47850453 | Limiting Assumptions in the Design of Peptidomimetics |
| Q41919670 | Lipid profile of rheumatoid arthritis patients treated with anti-tumor necrosis factor-alpha drugs changes according to disease activity and predicts clinical response |
| Q60503393 | Lipophilic methotrexate conjugates with glucose-lipoamino acid moieties: Synthesis and in vitro antitumor activity |
| Q46649572 | Liposomal gels for site-specific, sustained delivery of celecoxib: in vitro and in vivo evaluation |
| Q38955537 | Lithium Pharmacogenetics: Where Do We Stand? |
| Q96308167 | Lithium as a candidate treatment for COVID-19: Promises and pitfalls |
| Q90620115 | Lithium treatment in the era of personalized medicine |
| Q43651623 | Low-dose aspirin ameliorated hyperlipidemia, adhesion molecule, and chemokine production induced by high-fat diet in Sprague-Dawley rats |
| Q104583187 | Macrocyclic sulfone derivatives: Synthesis, characterization, in vitro biological evaluation and molecular docking |
| Q104935520 | Macrofilaricidal activity of the stembark ofStreblus asper and its major active constituents |
| Q41670448 | Management of patients with psoriasis treated with biological drugs needing a surgical treatment |
| Q104465961 | Marein ameliorates Ang II/hypoxia-induced abnormal glucolipid metabolism by modulating the HIF-1α/PPARα/γ pathway in H9c2 cells |
| Q58108382 | Marine bacteria and fungi as promising source for new antibiotics |
| Q113926230 | Marine biodiversity as a source of chemical diversity |
| Q91408599 | Matching pH values for antibody stabilization and crystallization suggest rationale for accelerated development of biotherapeutic drugs |
| Q90236906 | Mechanism of penehyclidine hydrochloride on a dysmenorrhea rat model |
| Q91276174 | Mechanisms underlying isoliquiritigenin-induced apoptosis and cell cycle arrest via ROS-mediated MAPK/STAT3/NF-κB pathways in human hepatocellular carcinoma cells |
| Q29010935 | Medical drugs from humus matter: Focus on mumie |
| Q38197555 | Medical management of the consequences of the Fukushima nuclear power plant incident |
| Q59725319 | Meeting the information needs of a national drug payer: aspirations of the guidelines from Australia |
| Q59923521 | Metabolic limitations of the use of nucleoside analogs in cancer therapy may be overcome by application of nanoparticles as drug carriers: A review |
| Q57342035 | Metals and oxidative homeostasis in Alzheimer's disease |
| Q46179529 | Metformin Protects against Experimental Acrylamide Neuropathy in Rats. |
| Q47766509 | Methyl Jasmonate Ameliorates Unpredictable Chronic Mild Stress-Induced Behavioral and Biochemical Alterations in Mouse Brain. |
| Q38640016 | MicroRNA Regulation of Airway Inflammation and Airway Smooth Muscle Function: Relevance to Asthma |
| Q38548766 | MicroRNA-Based Therapeutic Strategies for Targeting Mutant and Wild Type RAS in Cancer |
| Q36599274 | MicroRNAs and Noncoding RNAs in Hepatic Lipid and Lipoprotein Metabolism: Potential Therapeutic Targets of Metabolic Disorders |
| Q48546107 | MicroRNAs as CNS Drug Targets. |
| Q38556136 | MicroRNAs in Bone Balance and Osteoporosis |
| Q38246624 | Microarray gene and miRNA expression studies: looking for new therapeutic targets for frontotemporal lobar degeneration. |
| Q57283542 | Microbial esterases and ester prodrugs: An unlikely marriage for combating antibiotic resistance |
| Q93232632 | Microsponge: An emerging drug delivery strategy |
| Q61982605 | Migraine genetics and prospects for pharmacotherapy |
| Q95307757 | Mini review: The FDA-approved prescription drugs that induce ovulation in women with ovulatory problems |
| Q57074538 | Mitochondria: The biochemical power plants of cells |
| Q57074540 | Mitochondria: The biochemical power plants of cells |
| Q46322600 | Mitochondrial drugs come of age. |
| Q41108935 | Mitochondrially-imported RNA in drug discovery |
| Q62961761 | Modeling the nicotinic receptor loss in dementia using the nicotinic antagonist mecamylamine: Effects on human cognitive functioning |
| Q92655877 | Modified benzoxazolone (ABO-AA) based single photon emission computed tomography (SPECT) probes for 18 kDa translocator protein |
| Q92270822 | Modified-release oral pellets for duodenum delivery of doxycycline hyclate |
| Q60643597 | Modulation by adenosine A2A receptors of dopamine-mediated motor behavior as a basis for antiparkinson?s disease drugs |
| Q35210290 | Molecular Architecture of G Protein-Coupled Receptors. |
| Q36246995 | Molecular Characterization of A(1) and A(2a) Adenosine Receptors |
| Q47396901 | Molecular Mechanism and Clinical Relevance of Ketamine as Rapid-Acting Antidepressant |
| Q33849095 | Molecular dynamics guided design of tocoflexol: a new radioprotectant tocotrienol with enhanced bioavailability |
| Q91563420 | Molecular signaling of G-protein-coupled receptor in chronic heart failure and associated complications |
| Q57440659 | Molecular similarity and diversity approaches in chemoinformatics |
| Q95937984 | Monensin inhibits proliferation, migration, and promotes apoptosis of breast cancer cells via downregulating UBA2 |
| Q44721338 | Monoclonal gammopathy of undetermined significance in patients with psoriasis: is it really a side effect of biological therapy? |
| Q92466824 | Montelukast modifies simvastatin-induced myopathy and hepatotoxicity |
| Q57351094 | Mood disorders and their treatment: alterations in the regulation of receptor-G protein coupling |
| Q38405956 | Morin Inhibits Proliferation, Migration, and Invasion of Bladder Cancer EJ Cells via Modulation of Signaling Pathways, Cell Cycle Regulators, and Transcription Factor-Mediated MMP-9 Expression |
| Q92019069 | Mucosal gene expression changes induced by anti-TNF treatment in inflammatory bowel disease patients |
| Q104473070 | N-(3',4'-dimethoxycinnamonyl) anthranilic acid alleviates severe acute pancreatitis by inhibiting intestinal barrier dysfunction and NF-κB activation |
| Q38962399 | NS1209/SPD 502, A Novel Selective AMPA Antagonist for Stroke, Neuropathic Pain or Epilepsy? Drug Development Lessons Learned |
| Q57074476 | Nanobiotechnology: it's a small world after all |
| Q47936792 | Nanomedicine in Psychiatry: New Therapeutic Opportunities from Research on Small RNAs. |
| Q90788023 | Naphthoquinones, benzoquinones, and anthraquinones: Molecular docking, ADME and inhibition studies on human serum paraoxonase-1 associated with cardiovascular diseases |
| Q37136990 | Natural products and colon cancer: current status and future prospects |
| Q91836788 | Natural products and their derivatives as multifunctional ligands against Alzheimer's disease |
| Q92505113 | Near-infrared imaging of diseases: A nanocarrier approach |
| Q57275750 | Neglected diseases: in need of bare necessities and breakthroughs |
| Q35241159 | Network measures for chemical library design |
| Q38243629 | Network pharmacology: a Rosetta Stone for traditional Chinese medicine |
| Q57990424 | Neural-glial interaction in the spinal cord for the development and maintenance of nerve injury-induced neuropathic pain |
| Q56028066 | Neuronal nicotinic acetylcholine receptors as a target for the treatment of neuropathic pain |
| Q58852531 | Neuroprotection by A2A receptor antagonists |
| Q91480102 | Neuroprotection of rhGLP-1 in diabetic rats with cerebral ischemia/reperfusion injury via regulation of oxidative stress, EAAT2, and apoptosis |
| Q48837078 | Neuroprotective Effects of rhGLP-1 in Diabetic Rats with Cerebral Ischemia/Reperfusion Injury. |
| Q93091351 | Neuroprotective effects of clavulanic acid following permanent bilateral common carotid artery occlusion in rats |
| Q91682613 | New 3-unsubstituted isoxazolones as potent human neutrophil elastase inhibitors: Synthesis and molecular dynamic simulation |
| Q38377344 | New Horizons in Pediatric Psychopharmacology |
| Q56642269 | New Malaria Drugs (volume 71, number 1, 2010) |
| Q35219247 | New challenges in the epidemiology and treatment of visceral leishmaniasis in periurban areas. |
| Q62022853 | New class of hallucinogens: GABA-enhancing agents |
| Q59651481 | New insights on attention-deficit/hyperactivity disorder pharmacogenomics |
| Q99210901 | New multitarget directed benzimidazole-2-thiol-based heterocycles as prospective anti-radical and anti-Alzheimer's agents |
| Q35676180 | New regimens for reducing the duration of the treatment of drug-susceptible pulmonary tuberculosis. |
| Q37852563 | Next-Generation Antimalarial Drugs: Hybrid Molecules as a New Strategy in Drug Design |
| Q57913221 | Nicotine and tetrahydroaminoacradine: Evidence for improved attention in patients with dementia of the Alzheimer type |
| Q54285104 | Nimesulide/methyl β-cyclodextrin inclusion complexes: physicochemical characterization, solubility, dissolution, and biological studies. |
| Q98207665 | Nitrogen-containing flavonoid and their analogs with diverse B-ring in acetylcholinesterase and butyrylcholinesterase inhibition |
| Q90339374 | Nitroglycerin ameliorates liver injury and regulates adaptive immunity in mice |
| Q46806315 | Nobiletin Inhibits PDGF-BB-induced vascular smooth muscle cell proliferation and migration and attenuates neointimal hyperplasia in a rat carotid artery injury model |
| Q53056509 | Nociceptive Alteration by High Sucrose Diet in Hypoestrogenic Wistar Rats. |
| Q57026362 | Nonhormonal selective estrogen receptor modulator 1-(2-[4-{(3R,4S)-7-Methoxy-2, 2-dimethyl-3-phenyl-chroman-4yl}phenoxy]ethyl)pyrrolidine hydrochloride (ormeloxifene hydrochloride) for the treatment of breast cancer |
| Q57074457 | Nonprofit organizations and pharmaceutical research and development |
| Q36108563 | Northern Ring Conformation of Methanocarba-Adenosine 5'-Triphosphate Required for Activation of P2X Receptors. |
| Q93244730 | Noscapine, a possible drug candidate for attenuation of cytokine release associated with SARS-CoV-2 |
| Q92676625 | Novel 3-aryl-5-substituted-coumarin analogues: Synthesis and bioactivity profile |
| Q91158897 | Novel 5-(1-aryl-1H-pyrazol-3-yl)-1H-tetrazoles as glycogen phosphorylase inhibitors: An in vivo antihyperglycemic activity study |
| Q51618255 | Novel 5-Hydroxy, 5-Substituted Benzenesulfonamide Pyrimidine-2,4,6-Triones Attenuate Lipopolysaccharide-Induced Acute Lung Injury via Inhibition of the Gelatinases, MMP-2 and MMP-9. |
| Q92744584 | Novel analogs of sulfasalazine as system xc - antiporter inhibitors: Insights from the molecular modeling studies |
| Q93097567 | Novel antimicrobial peptide discovery using machine learning and biophysical selection of minimal bacteriocin domains |
| Q90454524 | Novel histone deacetylase inhibitors bearing a 4-piperidin-4-yl-triazole scaffold as antitumor agents |
| Q88543558 | Novel primary amine diazeniumdiolates-Chemical and biological characterization |
| Q91845277 | Novel steroid sulfatase inhibitors based on N-thiophosphorylated 3-(4-aminophenyl)-coumarin-7-O-sulfamates |
| Q42084376 | On BH3 Mimetics and Ca2+ Signaling. |
| Q92435851 | Opportunities and challenges of using five-membered ring compounds as promising antitubercular agents |
| Q42698436 | Opportunities and challenges provided by cloud repositories for bioinformatics-enabled drug discovery |
| Q92201960 | Optimization of pyrrolo[3,4-f]indole-5,7-dione and indole-5,6-dicarbonitrile derivatives as inhibitors of monoamine oxidase |
| Q38208275 | Optimized nonclinical safety assessment strategies supporting clinical development of therapeutic monoclonal antibodies targeting inflammatory diseases |
| Q104617610 | Oridonin alleviates d-GalN/LPS-induced acute liver injury by inhibiting NLRP3 inflammasome |
| Q90705087 | Oridonin ameliorates carbon tetrachloride-induced liver fibrosis in mice through inhibition of the NLRP3 inflammasome |
| Q99545920 | Osteoarthritis: Prognosis and emerging therapeutic approach for disease management |
| Q92431601 | Oxalomalate regulates the apoptosis and insulin secretory capacity in streptozotocin-induced pancreatic β-cells |
| Q57405393 | P1 and P2 receptors in cell growth and differentiation |
| Q63729229 | P2-mediated responses in osteoclasts and osteoclast-like cells |
| Q57405374 | P2Y receptors in brain astroglial cells: Identification of a gliotic P2Y receptor coupled to activation of a calcium-independent ras/ERK1/2 pathway |
| Q57405380 | PURINES 2000 meeting: Biochemical, pharmacological and clinical perspectives |
| Q89742460 | Paeoniflorin alleviates lipopolysaccharide-induced disseminated intravascular coagulation by inhibiting inflammation and coagulation activation |
| Q102381604 | Paeoniflorin inhibited nod-like receptor protein-3 inflammasome and NF-κB-mediated inflammatory reactions in diabetic foot ulcer by inhibiting the chemokine receptor CXCR2 |
| Q58605682 | Participation of ATP-sensitive K+ channels and μ-opioid receptors in the antinociceptive synergism of the paracetamol-tapentadol co-administration in the formalin-induced pain assay in mice |
| Q122978685 | Patenting the sun: Enclosing the scientific commons and transforming the university—ethical concerns |
| Q44874794 | Peptide Mimetic Drugs for Modulating Thrombosis and Hemostasis |
| Q53813992 | Peptide Mimetics: Fast-Forward Look. |
| Q85932919 | Periodontal disease: an oral manifestation of psoriasis or an occasional finding? |
| Q87877742 | Peripheral synergism between tramadol and ibuprofen in the formalin test |
| Q57084439 | Persistence of nicotinic agonist RJR 2403-induced working memory improvement in rats |
| Q38931450 | Perspectives in Designing Multifunctional Molecules in Antipsychotic Drug Discovery |
| Q92916924 | Pharmacodynamic interaction of 3α-hydroxymasticadienonic acid and diligustilide against indomethacin-induced gastric damage in rats |
| Q38266322 | Pharmacogenetics and future therapeutic scenarios: what affects the prediction of response to treatment with etanercept? |
| Q57074515 | Pharmacogenomics 2000 |
| Q57074520 | Pharmacogenomics 2000 |
| Q60439542 | Pharmacological and Toxicological Profile of Extract from Heliopsislongipes and Affinin |
| Q91607725 | Pharmacological interaction between NSAIDS with clomipramine and risperidone in mice visceral pain |
| Q47304873 | Pharmacological interaction of α-bisabolol and diclofenac on nociception, inflammation, and gastric integrity in rats. |
| Q60307174 | Pharmacology of cyanodothiepin (BTS 56 424), a selective 5-hydroxytryptamine reuptake inhibitor |
| Q91860378 | Pharmacology of mitochondrial permeability transition pore inhibitors |
| Q99631496 | Phase I safety, tolerability, and pharmacokinetic studies of tetramethylpyrazine nitrone in healthy Chinese volunteers |
| Q92479672 | Phloroglucinol averts isoprenaline hydrochloride induced myocardial infarction in rats |
| Q87059505 | Phosphate and thiophosphate biphenyl analogs as steroid sulfatase inhibitors |
| Q48057218 | Phytochemical Investigation, Antitumor Activity, and Hepatoprotective Effects of Acrocarpus fraxinifolius Leaf Extract |
| Q100472430 | Phytochemical conjugation as a potential semisynthetic approach toward reactive and reuse of obsolete sulfonamides against pathogenic bacteria |
| Q89903777 | Pivotal cytokines and their transcription factors are the targets of guluronic acid (G2013) for inhibiting the immunopathogenesis process of multiple sclerosis |
| Q114389995 | Placebo-controlled, double-blind, crossover study to investigate the hypoxia-protective effect of vinpocetine by psychophysiological methodology in healthy volunteers |
| Q58905306 | Platforms and networks in triterpenoid pharmacology |
| Q36726800 | Potent P2X7 Receptor Antagonists: Tyrosyl Derivatives Synthesized Using a Sequential Parallel Synthetic Approach |
| Q88156577 | Potential amelioration of nicotine-induced toxicity by nanocurcumin |
| Q61413693 | Potential mechanisms of mitochondrial cytochrome-C release during apoptosis |
| Q112281008 | Potential of enhancer of zeste homolog 2 inhibitors for the treatment of SWI/SNF mutant cancers and tumor microenvironment modulation |
| Q112217693 | Potential of nafimidone derivatives against co‐morbidities of epilepsy: In vitro, in vivo, and in silico investigations |
| Q98281653 | Potentiality of Q3 characterization of nanosystem: Surrogate data for obtaining a biowaiver |
| Q62066412 | Preclinical abuse potential assessment of the anticonvulsant zonisamide |
| Q60632222 | Preclinical approaches to examine novel concepts of the pathophysiology of depressive disorders: lessons learned from tree shrews |
| Q91790161 | Preclinical evaluation of a biobetter candidate: Pharmacokinetics and pharmacodynamics of GX-G3 in healthy and neutropenia-induced rats |
| Q63437487 | Preclinical progress with CHF2819, a novel orally active acetylcholinesterase inhibitor |
| Q62820446 | Prediction of polymorphicN-acetylation of new drug candidates by correlation with human NAT1 and NAT2 |
| Q35681911 | Predictors of Medication Adherence in Patients with Rheumatoid Arthritis |
| Q51406150 | Preparation and Sonodynamic Antitumor Effect of Protohemin-Conjugated Multiwalled Carbon Nanotubes Functionalized with Carboxylic Group. |
| Q57342456 | Preparation and characterization of chitosan microparticles for oral sustained delivery of gliclazide: in vitro/in vivo evaluation |
| Q90260571 | Preparation, characterization, and sonodynamic antitumor effect of the folate receptor targeted FA-EN-β-CD containing hematoporphyrin in vitro |
| Q58555933 | Preparation, optimization, and pharmacokinetic study of nanoliposomes loaded with triacylglycerol-bound punicic acid for increased antihepatotoxic activity |
| Q63456696 | Presynaptic diadenosine polyphosphate receptors: Interaction with other neurotransmitter systems |
| Q36782594 | Prevention of Visual Stress and Migraine With Precision Spectral Filters |
| Q56429617 | Prevention of “learned helplessness” in the rat by hydroxyzine |
| Q51075139 | Preventive effect of American ginseng against premature ovarian failure in a rat model. |
| Q91948220 | Preventive effect of nerolidol on isoproterenol induced myocardial damage in Wistar rats: Evidences from biochemical and histopathological studies |
| Q98166570 | Probing 3CL protease: Rationally designed chemical moieties for COVID-19 |
| Q30845109 | Progress in the analysis of multiple activity profile of screening data using computational approaches |
| Q57405404 | Prolonged agonist exposure induces imbalance of A1 and A2 receptor-mediated functions in rat brain slices |
| Q57762974 | Propensity score for the analysis of observational data: an introduction and an illustrative example |
| Q93202753 | Prospects of multitarget drug designing strategies by linking molecular docking and molecular dynamics to explore the protein-ligand recognition process |
| Q53052452 | Protective Effect of Metformin against Acute Inflammation and Oxidative Stress in Rat. |
| Q62949939 | Protective effect of curcumin, aCurcuma longaconstituent, in early colonic inflammation in rats |
| Q90880953 | Protective effects of quercetin against inflammation and oxidative stress in a rabbit model of knee osteoarthritis |
| Q58087689 | Protective role of fucoxanthin in diethylnitrosamine-induced hepatocarcinogenesis in experimental adult rats |
| Q64130982 | Protective role of sitagliptin against oxidative stress in a kainic acid-induced status epilepticus in rats models via Nrf2/HO-1 pathway |
| Q61337152 | Proteinase-activated receptor expression and function in the brain |
| Q60691052 | Proteinase-activated receptors and nociceptive pathways |
| Q115171710 | Proteinase-activated receptors and the pathophysiology of pulmonary fibrosis |
| Q102371561 | Proteolysis targeting chimera (PROTAC) for epidermal growth factor receptor enhances anti-tumor immunity in non-small cell lung cancer |
| Q61800899 | Psychopharmacological effects of an imino-thiazolidine derivative antidepressant candidate, EGYT-4201 |
| Q38998475 | Psychotropic Drug Development Strategies that Target Neuropsychiatric Etiologies in Alzheimer's and Parkinson's Diseases |
| Q36058000 | Purification and Recognition of Recombinant Mouse P2X(1) Receptors Expressed in a Baculovirus System |
| Q57405394 | Purines '96: Molecular, pharmacological and therapeutic advances |
| Q57405395 | Purines and cell death |
| Q57405405 | Purinoceptor nomenclature: A status report |
| Q57405397 | Purinoceptors in the central nervous system |
| Q28834245 | Pyran Template Approach to the Design of Novel A3 Adenosine Receptor Antagonists |
| Q89653613 | QSAR studies on benzothiophene derivatives as Plasmodium falciparum N-myristoyltransferase inhibitors: Molecular insights into affinity and selectivity |
| Q50453050 | Quercetin Induces Antiproliferative Activity Against Human Hepatocellular Carcinoma (HepG2) Cells by Suppressing Specificity Protein 1 (Sp1). |
| Q92740730 | Quinalizarin induces cycle arrest and apoptosis via reactive oxygen species-mediated signaling pathways in human melanoma A375 cells |
| Q87476673 | Quinic acid derivative KZ-41 exhibits radiomitigating activity in preclinical models of radiation injury |
| Q46507854 | RGD Peptide-Based Target Drug Delivery of Doxorubicin Nanomedicine. |
| Q57074433 | Radiation Drugs-A Hot Topic |
| Q57074423 | Radiation Drugs-Still a Hot Topic |
| Q61483298 | Radioresistant Burkitt?s lymphoma cells exhibit defective MAPK signalling |
| Q57470806 | Reaching toward underexplored targets in antibacterial drug design |
| Q47980008 | Recent Advances in GLP-1 Receptor Agonists for Use in Diabetes Mellitus |
| Q46324333 | Recent Advances on Bioactive Constituents in Ferula. |
| Q38989291 | Recent Developments of Hydrazide/Hydrazone Derivatives and Their Analogs as Anticonvulsant Agents in Animal Models |
| Q125825492 | Recent advances in the development of novel anti‐cancer drugs targeting cancer stem/progenitor cells |
| Q57074593 | Recent advances in the generation of chemical diversity libraries |
| Q59171613 | Recent developments in the field of A3 adenosine receptor antagonists |
| Q57734397 | Recent progress in the study of the intracellular functions of diadenosine polyphosphates |
| Q94566375 | Recent strategies for the development of oral medicines for the treatment of visceral leishmaniasis |
| Q38243631 | Redox regulation of cancer metastasis: molecular signaling and therapeutic opportunities |
| Q51100991 | Relationship between blood levels and the anti-hyperalgesic effect of ketoprofen in the rat. |
| Q95269629 | Repurposing current therapeutics for treating COVID-19: A vital role of prescription records data mining |
| Q90753783 | Repurposing therapeutic agents and herbal medicines to defeat viral nemesis |
| Q98242687 | Repurposing topical triclosan for cutaneous leishmaniasis: Preclinical efficacy in a murine Leishmania (L.) amazonensis model |
| Q92028340 | Response to recent commentaries regarding the involvement of angiotensin-converting enzyme 2 (ACE2) and renin-angiotensin system blockers in SARS-CoV-2 infections |
| Q113110140 | Restoration of shock-suppressed behavior by treatment with (+)-5-methyl-10,11-dihydro-5H-dibenzo[a, d]cyclohepten-5, 10-imine (MK-801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties |
| Q53642877 | Resveratrol Ameliorates the Components of Hepatic Inflammation and Apoptosis in a Rat Model of Streptozotocin-Induced Diabetes. |
| Q103732534 | Review of registered clinical trials for the treatment of COVID-19 |
| Q56031122 | Review of the effects of 17α-estradiol in humans: a less feminizing estrogen with neuroprotective potential |
| Q97430314 | Revisiting potential druggable targets against SARS-CoV-2 and repurposing therapeutics under preclinical study and clinical trials: A comprehensive review |
| Q36076482 | Riboflavin: Inhibitory Effects on Receptors, G-Proteins, and Adenylate Cyclase. |
| Q60439576 | Role of COX-1- and COX-2-synthesized prostaglandins in a rat model of arthritic pain |
| Q41241386 | Role of adenosine in asthma |
| Q101578601 | Role of mineralocorticoid receptor antagonists in kidney diseases |
| Q60733395 | Role of neurophysiology in the clinical practice of primary pediatric headaches |
| Q92107622 | Ropivacaine inhibits proliferation, invasion, migration and promotes apoptosis of papillary thyroid cancer cells via regulating ITGA2 expression |
| Q47946109 | S-Adenosyl Methionine in the Therapy of Depression and Other Psychiatric Disorders |
| Q93196912 | SCN11A mRNA levels in female bipolar disorder PBMCs as tentative biomarker for distinct patient sub-phenotypes |
| Q38611360 | Safety of Anti-TNF Therapies in Immune-Mediated Inflammatory Diseases: Focus on Infections and Malignancy. |
| Q50501562 | Sanguinarine Induces Apoptosis of Human Oral Squamous Cell Carcinoma KB Cells via Inactivation of the PI3K/Akt Signaling Pathway. |
| Q92872952 | Schiff base-nickel, palladium, and platinum complexes derived from N-cyclohexyl hydrazine carbothioamide and 3-hydroxy-4-methoxybenzaldehyde: Selective antiproliferative and proapoptotic effects against colorectal carcinoma |
| Q38829875 | Schisandrae Fructus Inhibits IL-1β-Induced Matrix Metalloproteinases and Inflammatory Mediators Production in SW1353 Human Chondrocytes by Suppressing NF-κB and MAPK Activation |
| Q61698318 | Schistosoma mansoni antigens modulate allergic response in vitro in cells of asthmatic individuals |
| Q94566754 | Schizophrenia-associated gene dysbindin-1 and tardive dyskinesia |
| Q57338672 | Scientific literature mining for drug discovery: a case study on obesity |
| Q60636693 | Screening of antipsychotic drugs in animal models |
| Q57265935 | Screening of natural compounds and their derivatives as potential protein kinase C inhibitors |
| Q92676693 | Selected pharmacotherapy agents as antiproliferative and anti-inflammatory compounds |
| Q60583310 | Selective binding to human genomic sequences of two synthetic analogues structurally related to U-71184 and adozelesin |
| Q58094606 | Selective cytotoxic activity and DNA damage by an epoxyalkyl galactopyranoside |
| Q53270119 | Self-nanoemulsifying drug delivery system of trans-cinnamic acid: formulation development and pharmacodynamic evaluation in alloxan-induced type 2 diabetic rat model. |
| Q43470029 | Self-reported adherence to a home-based exercise program among patients affected by psoriatic arthritis with minimal disease activity |
| Q85932881 | Seminars in research 2013: joint experiences using biologics in rheumatology and dermatology |
| Q59487692 | Sensitivity and reproducibility of indirect calorimetry in measurement of resting metabolic rate |
| Q40150045 | Serum Derived Transfer Factor Stimulates the Innate Immune System to Improve Survival Traits in High Risk Pathogen Scenarios. |
| Q57236378 | Shape-mimetics of G-protein-coupled receptors in therapeutic drug design and screening |
| Q91866086 | Shenmai injection improves the postoperative immune function of papillary thyroid carcinoma patients by inhibiting differentiation into Treg cells via miR-103/GPER1 axis |
| Q100534366 | Sigma-1 receptor antagonist (BD-1063) potentiates the antinociceptive effect of quercetin in neuropathic pain induced by chronic constriction injury |
| Q60307248 | Significance of Single Variables in Defining Adequate Animal Models to Assess the Efficacy of New Radionuclide Decorporation Agents: Using the Contamination Dose as an Example |
| Q58550057 | Silver carbene complexes: An emerging class of anticancer agents |
| Q35740706 | Small Molecules in the Treatment of Psoriasis |
| Q47965403 | Small Scaffolds, Big Potential: Developing Miniature Proteins as Therapeutic Agents |
| Q35801078 | Small-Molecule Regulators of MicroRNAs in Biomedicine |
| Q98213543 | Smoking and COVID-19: Similar bronchial ACE2 and TMPRSS2 expression and higher TMPRSS4 expression in current versus never smokers |
| Q98227509 | Snake venom-derived bradykinin-potentiating peptides: A promising therapy for COVID-19? |
| Q92474058 | Spidroin in carbopol-based gel promotes wound healing in earthworm's skin model |
| Q90237008 | Spontaneous mutations conferring antibiotic resistance to antitubercular drugs at a range of concentrations in Mycobacterium smegmatis |
| Q57342832 | Stability of poly(Acrylic Acid)-grafted phospholipid liposomes in gastrointestinal conditions |
| Q62664606 | Statistical learning approach for predicting specific pharmacodynamic, pharmacokinetic, or toxicological properties of pharmaceutical agents |
| Q62887219 | Stearoyl-CoA desaturase: a new therapeutic target of liver steatosis |
| Q101557352 | Step toward repurposing drug discovery for COVID-19 therapeutics through in silico approach |
| Q86301008 | Steroid Sulfatase Inhibitors Based on Phosphate and Thiophosphate Flavone Analogs |
| Q98185083 | Stevioside protects against rhabdomyolysis-induced acute kidney injury through PPAR-γ agonism in rats |
| Q91798331 | Stilbene derivatives as new perspective in antifungal medicinal chemistry |
| Q94581202 | Structural and biological survey of 7-chloro-4-(piperazin-1-yl)quinoline and its derivatives |
| Q36210776 | Structure Activity Relationships for Derivatives of Adenosine-5'-Triphosphate as Agonists at P(2) Purinoceptors: Heterogeneity Within P(2X) and P(2Y) Subtypes |
| Q56484325 | Structure-activity relationships for nicotine analogs comparing competition for [3H]nicotine binding and psychotropic potency |
| Q91215795 | Structure-activity study of fluorine or chlorine-substituted cinnamic acid derivatives with tertiary amine side chain in acetylcholinesterase and butyrylcholinesterase inhibition |
| Q50676306 | Study on action mechanism of 1-(4-methoxy-2-methylphenyl)piperazine (MMPP) in acquisition, formation, and consolidation of memory in mice. |
| Q91682606 | Substituted chloroacetamides as potential cancer stem cell inhibitors: Synthesis and biological evaluation |
| Q100305453 | Superiority of cilostazol among antiplatelet FDA-approved drugs against COVID 19 Mpro and spike protein: Drug repurposing approach |
| Q38644187 | Supra-Additive Interaction of Docosahexaenoic Acid and Naproxen and Gastric Safety on the Formalin Test in Rats |
| Q101557486 | Surface receptor-mediated targeted drug delivery systems for enhanced cancer treatment: A state-of-the-art review |
| Q57342836 | Sustained ophthalmic in situ gel of ketorolac tromethamine: rheology and in vivo studies |
| Q48238375 | Synergism between Naproxen and Rutin in a Mouse Model of Visceral Pain |
| Q87271736 | Synergism between tramadol and parecoxib in the orofacial formalin test |
| Q38641418 | Synergistic Interaction of Matricaria Chamomilla Extract with Diclofenac and Indomethacin on Carrageenan-Induced Paw Inflammation in Rats |
| Q47937429 | Synergistic Interaction of a Gabapentin- Mangiferin Combination in Formalin-Induced Secondary Mechanical Allodynia and Hyperalgesia in Rats Is Mediated by Activation of NO-Cyclic GMP-ATP-Sensitive K+ Channel Pathway. |
| Q60439580 | Synergistic antinociceptive interaction between aspirin and tramadol, the atypical opioid analgesic, in the rat |
| Q98185066 | Synergistic interaction between 4-allyl-1-hydroxy-2-methoxybenzene (eugenol) and diclofenac: An isobolograpic analysis in Wistar rats |
| Q104284156 | Synergistic interaction between B vitamins and statins to counter nociception in rats |
| Q91315220 | Synergistic interaction between docosahexaenoic acid and diclofenac on inflammation, nociception, and gastric security models in rats |
| Q104473120 | Synergistic protective effects between docosahexaenoic acid and omeprazole on the gastrointestinal tract in the indomethacin-induced injury model |
| Q93042869 | Synergistic terpene combinations as larvicides against the dengue vector Aedes aegypti Linn |
| Q51202412 | Synthesis and Biological Evaluation of Novel Carbohydrate-Derived Derivatives of Erlotinib. |
| Q38796610 | Synthesis and Cytotoxic Evaluation of Monocarbonyl Analogs of Curcumin as Potential Anti-Tumor Agents |
| Q63363564 | Synthesis and Evaluation as Antitubercular Agents of 5-Arylethenyl and 5-(Hetero)aryl-3-Isoxazolecarboxylate |
| Q51647052 | Synthesis and Evaluation of a New Series of 8-(2-Nitroaryl)Xanthines as Adenosine Receptor Ligands. |
| Q114865575 | Synthesis and Macrofilaricidal Activity of Substituted 2-Hydroxy/5-Hydroxy/2-Methyl-1,4-Naphthoquinones |
| Q105704700 | Synthesis and Myorelaxant Activity of Fused 1,4-Dihydropyridines on Isolated Rabbit Gastric Fundus |
| Q41451586 | Synthesis and Pharmacological Evaluation of Indole Derivatives as Deaza Analogues of Potent Human Neutrophil Elastase Inhibitors. |
| Q36178575 | Synthesis and Structure-Activity Relationships of Pyridoxal-6-arylazo-5'-phosphate and Phosphonate Derivatives as P2 Receptor Antagonists |
| Q59545706 | Synthesis and anti-Helicobacter pylori properties of NO-donor/metronidazole hybrids and related compounds |
| Q54285101 | Synthesis and antimetastatic effects of E-salignone amide derivatives. |
| Q99586157 | Synthesis and antimicrobial activity of the hybrid molecules between amoxicillin and derivatives of benzoic acid |
| Q91682655 | Synthesis and antimicrobial evaluation of piperic acid amides and their lower homologues |
| Q91504438 | Synthesis and antituberculosis activity of new acylthiosemicarbazides designed by structural modification |
| Q39013715 | Synthesis and characterization of new curcumin derivatives as potential chemotherapeutic and antioxidant agents |
| Q90902523 | Synthesis and cytotoxic evaluation of apioarabinofuranosyl pyrimidines |
| Q91588278 | Synthesis and docking studies of N-(5-(alkylthio)-1,3,4-oxadiazol-2-yl)methyl)benzamide analogues as potential alkaline phosphatase inhibitors |
| Q101212740 | Synthesis and in vitro antileishmanial efficacy of benzyl analogues of nifuroxazide |
| Q114869177 | Synthesis and screening of substituted 1,4-naphthoquinones (NPQs) as antifilarial agents |
| Q51320454 | Synthesis of Five- and Six-Membered N-Phenylacetamido Substituted Heterocycles as Formyl Peptide Receptor Agonists. |
| Q87691617 | Synthesis of new thiobarbituric acid derived spiroheterobicyclic compounds and their antimicrobial activity |
| Q90339451 | Synthesis of novel N-substitutedphenyl-6-oxo-3-phenylpyridazine derivatives as cyclooxygenase-2 inhibitors |
| Q92511367 | Synthesis of novel flexible tamoxifen analogues to overcome CYP2D6 polymorphism and their biological evaluation on MCF-7 cell line |
| Q38804001 | Synthesis of p-O-Alkyl Salicylanilide Derivatives as Novel EGFR Inhibitors |
| Q93357938 | Synthesis, anticonvulsant screening, and molecular modeling studies of new arylalkylimidazole oxime ether derivatives |
| Q93026463 | Synthesis, biological evaluation, and molecular modeling of nitrile-containing compounds: Exploring multiple activities as anti-Alzheimer agents |
| Q57283544 | Synthesis, carbonic anhydrase inhibitory activity and antioxidant activity of some 1,3-oxazine derivatives |
| Q98154196 | Synthesis, characterization, and anti-cancer activity of new chalcone derivatives containing naphthalene and fluorine moieties |
| Q92967812 | Synthesis, characterization, molecular docking evaluation, antidepressant, and anti-Alzheimer effects of dibenzylidene ketone derivatives |
| Q91540283 | Synthesis, evaluation, molecular docking, and molecular dynamics studies of novel N-(4-[pyridin-2-yloxy]benzyl)arylamine derivatives as potential antitubercular agents |
| Q90630681 | Synthesis, in vivo and in silico evaluation of novel 2,3-dihydroquinazolin-4(1H)-one derivatives as potential anticonvulsant agents |
| Q93026777 | Synthesis, in vivo anticonvulsant testing, and molecular modeling studies of new nafimidone derivatives |
| Q91409443 | Synthesis, molecular modeling studies, ADME prediction of arachidonic acid carbamate derivatives, and evaluation of their acetylcholinesterase activity |
| Q97543051 | TWIRLS, a knowledge-mining technology, suggests a possible mechanism for the pathological changes in the human host after coronavirus infection via ACE2 |
| Q90479658 | Tadalafil: 15 years' journey in male erectile dysfunction and beyond |
| Q38584755 | Targeting MicroRNAs in Prevention and Treatment of Neurodegenerative Disorders. |
| Q100305524 | Targeting N-acetylgalactosaminyltransferase for anticancer therapy |
| Q58291538 | Targeting Platelet G Protein-Coupled Receptors for Antithrombotic Therapy |
| Q38585471 | Targeting c-Met in Cancer by MicroRNAs: Potential Therapeutic Applications in Hepatocellular Carcinoma |
| Q59524461 | Targeting local tissues by transdermal application: Understanding drug physicochemical properties that best exploit protein binding and blood flow effects |
| Q89672794 | Targeting neutrophils using novel drug delivery systems in chronic respiratory diseases |
| Q33915847 | Targeting the Lipid Metabolic Pathways for the Treatment of Malaria |
| Q34055110 | Targeting the Pentose Phosphate Pathway in Syndrome X-related Cardiovascular Complications |
| Q34054988 | Tat-Mediated Peptide Intervention in Analgesia and Anesthesia. |
| Q94479109 | Telmisartan as tentative angiotensin receptor blocker therapeutic for COVID-19 |
| Q85932909 | Ten-year drug survival of anti-TNF agents in the treatment of inflammatory arthritides |
| Q61824551 | Thalassemic Trait Prevalence in Patients Affected by Psoriatic Arthritis in Anti-TNF Treatment |
| Q57146931 | Thalidomide Inhibits Adhesion Molecules in Experimental Acute Pancreatitis-Associated Lung Injury |
| Q39093095 | The Antinociceptive Effect of a Tapentadol-Ketorolac Combination in a Mouse Model of Trigeminal Pain is Mediated by Opioid Receptors and ATP-Sensitive K+ Channels. |
| Q53084449 | The Antinociceptive Effects of Tramadol and/or Gabapentin on Rat Neuropathic Pain Induced by a Chronic Constriction Injury. |
| Q57074503 | The Biotechnology industry in a period of opportunity and uncertainty |
| Q56331175 | The EPIPSOFIRE project: A Preliminary Report |
| Q51729573 | The Effect of Experimental Thyroid Dysfunction on Markers of Oxidative Stress in Rat Pancreas. |
| Q48308905 | The Effect of Gabapentin and Tramadol in Cancer Pain Induced by Glioma Cell in Rat Femur. |
| Q56514152 | The Estonian Genome Project |
| Q35660234 | The Lymphocyte Potassium Channels Kv1.3 and KCa3.1 as Targets for Immunosuppression |
| Q47819498 | The Molecular Basis of Insomnia: Implication for Therapeutic Approaches |
| Q96643471 | The National Institutes of Health Chemical Countermeasures Research Program (NIH CCRP): A collaborative opportunity to develop effective and accessible chemical medical countermeasures for the American people |
| Q48360501 | The Neurotensin NTS1 Receptor Agonist PD149163 Produces Antidepressant-Like Effects in the Forced Swim Test: Further Support for Neurotensin as a Novel Pharmacologic Strategy for Antidepressant Drugs. |
| Q110409546 | The Role of Chemogenomics in the Pharmaceutical Industry |
| Q38574546 | The Role of MicroRNAs in the Chemoresistance of Breast Cancer |
| Q53774865 | The Role of Potassium Channels in the Vasodilatation Induced by Resveratrol and Naringenin in Isolated Human Umbilical Vein. |
| Q38529935 | The Role of miR-21 in Cancer |
| Q41892975 | The Utility of Platelet and Coagulation Testing of Antithrombotics: Fusing Science with Patient Care |
| Q91480079 | The compound 2-(naphthalene-2-thio)-5,8-dimethoxy-1,4-naphthoquinone induces apoptosis via reactive oxygen species-regulated mitogen-activated protein kinase, protein kinase B, and signal transducer and activator of transcription 3 signaling in huma |
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| Q91580827 | The current drug discovery landscape for trypanosomiasis and leishmaniasis: Challenges and strategies to identify drug targets |
| Q50675031 | The discriminative stimulus effects of the neurotensin NTS1 receptor agonist PD149163 in rats: stimulus generalization testing with dopamine D1 and D2 receptor ligands. |
| Q42230300 | The effect of mild to moderate renal impairment on the pharmacokinetics of the nucleoside analog hepatitis C virus polymerase inhibitor mericitabine |
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| Q60690604 | The endocannabinoid and endovanilloid systems and their interactions in neuropathic pain |
| Q38211832 | The evolving drug development landscape: from blockbusters to niche busters in the orphan drug space |
| Q62746874 | The homocysteine pathway: A new target for Alzheimer disease treatment? |
| Q60691055 | The inflammatory response |
| Q98612409 | The involvement of protein TNFSF18 in promoting p-STAT1 phosphorylation to induce coronary microcirculation disturbance in atherosclerotic mouse model |
| Q96163235 | The mechanism of Arhalofenate in alleviating hyperuricemia-Activating PPARγ thereby reducing caspase-1 activity |
| Q56390353 | The nootropic concept and its prospective implications |
| Q56514116 | The novel nootropic compound DM232 (UNIFIRAM) ameliorates memory impairment in mice and rats |
| Q48144399 | The potential of radiolabeled chemotherapeutics in tumor diagnosis: Preliminary investigations with 68 Ga-gemcitabine. |
| Q91132654 | The potential of siRNA based drug delivery in respiratory disorders: Recent advances and progress |
| Q58854998 | The proteasome as a potential target for chemotherapy of African trypanosomiasis |
| Q92319951 | The protective effect of kaempferol on heart via the regulation of Nrf2, NF-κβ, and PI3K/Akt/GSK-3β signaling pathways in isoproterenol-induced heart failure in diabetic rats |
| Q91948303 | The protective effect of syringic acid on dextran sulfate sodium-induced experimental colitis in BALB/c mice |
| Q60632179 | The relationship between melatonin and cortisol rhythms: clinical implications of melatonin therapy |
| Q57513959 | The role of GABAB receptors in depression and antidepressant-related behavioural responses |
| Q60439557 | The sunflower seed test: a simple procedure to evaluate forelimb motor dysfunction after brain ischemia |
| Q89110295 | The use of aliskiren as an antifibrotic drug in experimental models: A systematic review |
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