Abstract is: Alcohol dehydrogenase 1A is an enzyme that in humans is encoded by the ADH1A gene. This gene encodes class I alcohol dehydrogenase, alpha subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. This gene is monomorphic and predominant in fetal and infant livers, whereas the genes encoding beta and gamma subunits are polymorphic and strongly expressed in adult livers.
| P594 | Ensembl gene ID | ENSG00000187758 |
| P704 | Ensembl transcript ID | ENST00000209668 |
| ENST00000503461 | ||
| ENST00000511656 | ||
| P351 | Entrez Gene ID | 124 |
| P2888 | exact match | http://identifiers.org/ncbigene/124 |
| P646 | Freebase ID | /m/03g_rrb |
| P353 | HGNC gene symbol | ADH1A |
| P354 | HGNC ID | 249 |
| P593 | HomoloGene ID | 88335 |
| P6366 | Microsoft Academic ID | 2779019462 |
| P492 | OMIM ID | 103700 |
| 103700 | ||
| P639 | RefSeq RNA ID | NM_000667 |
| P2892 | UMLS CUI | C1412235 |
| P1057 | chromosome | human chromosome 4 | Q836605 |
| P4196 | cytogenetic location | 4q23 | |
| P660 | EC enzyme classification | alcohol dehydrogenase (NAD) | Q410754 |
| P688 | encodes | Alcohol dehydrogenase 1A (class I), alpha polypeptide | Q21155117 |
| P5572 | expressed in | testicle | Q9384 |
| gallbladder | Q64386 | ||
| duodenum | Q134955 | ||
| ascending aorta | Q2349469 | ||
| right lung | Q5938041 | ||
| right lobe of liver | Q6493472 | ||
| subcutaneous adipose tissue | Q30015788 | ||
| Descending thoracic aorta | Q66592966 | ||
| right coronary artery | Q429285 | ||
| left coronary artery | Q744391 | ||
| P703 | found in taxon | Homo sapiens | Q15978631 |
| P645 | genomic end | 100212185 | |
| 99291003 | |||
| P644 | genomic start | 100197524 | |
| 99276369 | |||
| P684 | ortholog | Adh1 | Q18247425 |
| Adh6 | Q24423972 | ||
| P2548 | strand orientation | reverse strand | Q22809711 |
FileName: PBB GE ADH1A 207820 at fs.png
Description: Gene expression pattern of the ADH1A gene.
Artist: AndrewGNF at English Wikipedia
Work is copyrighted.
License: CC BY-SA 3.0
Attribution is required.
| Q27593693 | hsa-miR-132-3p | regulates (molecular biology) | P128 |
| Q21155117 | Alcohol dehydrogenase 1A (class I), alpha polypeptide | encoded by | P702 |
| cy | ADH1A | wikipedia |
| ADH1A | wikipedia | |
| ADH1A | wikipedia |
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