Abstract is: RAC(Rho family)-alpha serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene. This enzyme belongs to the AKT subfamily of serine/threonine kinases that contain SH2 (Src homology 2-like) protein domains. It is commonly referred to as PKB, or by both names as "Akt/PKB".
| P11277 | CIViC gene ID | 2 |
| P594 | Ensembl gene ID | ENSG00000142208 |
| P704 | Ensembl transcript ID | ENST00000349310 |
| ENST00000402615 | ||
| ENST00000407796 | ||
| ENST00000544168 | ||
| ENST00000553506 | ||
| ENST00000553797 | ||
| ENST00000554192 | ||
| ENST00000554581 | ||
| ENST00000554585 | ||
| ENST00000554826 | ||
| ENST00000554848 | ||
| ENST00000555380 | ||
| ENST00000555458 | ||
| ENST00000555528 | ||
| ENST00000556836 | ||
| ENST00000557552 | ||
| ENST00000610370 | ||
| ENST00000649815 | ||
| ENST00000682269 | ||
| ENST00000683058 | ||
| ENST00000683722 | ||
| ENST00000684058 | ||
| P351 | Entrez Gene ID | 207 |
| P2888 | exact match | http://identifiers.org/ncbigene/207 |
| P646 | Freebase ID | /m/02x2zfx |
| P353 | HGNC gene symbol | AKT1 |
| P354 | HGNC ID | 391 |
| P593 | HomoloGene ID | 3785 |
| P6366 | Microsoft Academic ID | 154137905 |
| P492 | OMIM ID | 164730 |
| 164730 | ||
| P10283 | OpenAlex ID | C154137905 |
| P639 | RefSeq RNA ID | NM_001014431 |
| NM_001014432 | ||
| NM_001382430 | ||
| NM_001382431 | ||
| NM_001382432 | ||
| NM_001382433 | ||
| NM_005163 | ||
| XR_002957536 | ||
| P2892 | UMLS CUI | C0812228 |
| P1057 | chromosome | human chromosome 14 | Q138955 |
| P4196 | cytogenetic location | 14q32.33 | |
| P688 | encodes | AKT serine/threonine kinase 1 | Q21114990 |
| RAC-alpha serine/threonine-protein kinase | Q21140482 | ||
| P5572 | expressed in | gallbladder | Q64386 |
| right coronary artery | Q429285 | ||
| body of stomach | Q3270352 | ||
| ganglionic eminence | Q4133185 | ||
| ventricular zone | Q28455175 | ||
| muscle layer of sigmoid colon | Q66511231 | ||
| right adrenal cortex | Q66566695 | ||
| left adrenal cortex | Q66566697 | ||
| stromal cell of endometrium | Q66592424 | ||
| right adrenal gland | Q66715642 | ||
| P703 | found in taxon | Homo sapiens | Q15978631 |
| P2293 | genetic association | colorectal cancer | Q188874 |
| breast cancer | Q128581 | ||
| Proteus syndrome | Q281115 | ||
| Cowden syndrome 1 | Q1138188 | ||
| P645 | genomic end | 104795751 | |
| 105262088 | |||
| P644 | genomic start | 104769349 | |
| 105235686 | |||
| P684 | ortholog | Akt1 | Q18247674 |
| Akt1 | Q24371776 | ||
| akt-2 | Q29692318 | ||
| akt-1 | Q29706986 | ||
| Akt1 | Q29720717 | ||
| akt1 | Q29747314 | ||
| P2548 | strand orientation | reverse strand | Q22809711 |
FileName: PBB GE AKT1 207163 s at fs.png
Description: Gene expression pattern of the AKT1 gene.
Artist: AndrewGNF at en.wikipedia
Work is copyrighted.
License: CC BY-SA 3.0
Attribution is required.
| Q27593177 | hsa-miR-100-5p |
| Q27595342 | hsa-miR-105-5p |
| Q27593173 | hsa-miR-125b-5p |
| Q27594812 | hsa-miR-133b |
| Q27594720 | hsa-miR-143-3p |
| Q27594280 | hsa-miR-149-3p |
| Q27594358 | hsa-miR-155-5p |
| Q27594379 | hsa-miR-185-5p |
| Q27595208 | hsa-miR-188-5p |
| Q27593106 | hsa-miR-192-3p |
| Q27593625 | hsa-miR-193b-3p |
| Q27592873 | hsa-miR-199a-3p |
| Q27593328 | hsa-miR-19a-3p |
| Q27593963 | hsa-miR-27a-5p |
| Q27594627 | hsa-miR-302a-3p |
| Q27594631 | hsa-miR-302b-3p |
| Q27594629 | hsa-miR-302c-3p |
| Q27594625 | hsa-miR-302d-3p |
| Q27594014 | hsa-miR-3191-5p |
| Q27593142 | hsa-miR-326 |
| Q27594002 | hsa-miR-330-5p |
| Q27593626 | hsa-miR-365a-3p |
| Q27593755 | hsa-miR-365b-3p |
| Q27594724 | hsa-miR-378a-3p |
| Q27594450 | hsa-miR-378b |
| Q27593027 | hsa-miR-378c |
| Q27594584 | hsa-miR-378d |
| Q27594737 | hsa-miR-378e |
| Q27592749 | hsa-miR-378f |
| Q27594730 | hsa-miR-378h |
| Q27594430 | hsa-miR-378i |
| Q27593553 | hsa-miR-422a |
| Q27593734 | hsa-miR-451a |
| Q27594753 | hsa-miR-4638-3p |
| Q27592912 | hsa-miR-4742-3p |
| Q27594143 | hsa-miR-4757-3p |
| Q27593478 | hsa-miR-496 |
| Q27594075 | hsa-miR-518c-5p |
| Q27593380 | hsa-miR-625-3p |
| Q27593088 | hsa-miR-6503-3p |
| Q27593445 | hsa-miR-654-3p |
| Q27593396 | hsa-miR-6764-3p |
| Q27594396 | hsa-miR-6817-3p |
| Q27594479 | hsa-miR-6824-3p |
| Q27593771 | hsa-miR-6866-3p |
| Q27594787 | hsa-miR-6873-3p |
| Q27593143 | hsa-miR-708-5p |
| Q27594530 | hsa-miR-7110-3p |
| Q27907100 | AKT1 E17K |
| Q56241018 | AKT1 Overexpression |
| Q28371079 | AKT1 Q79K |
| Q105669122 | AKT1 S473 Phosphorylation |
| Q102751733 | 3q29 copy number variation syndrome |
| Q30225524 | 4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression |
| Q30225483 | AGE/RAGE pathway |
| Q30102296 | AMP-activated protein kinase (AMPK) signaling |
| Q84972217 | Acute viral myocarditis |
| Q30225505 | Alpha 6 beta 4 signaling pathway |
| Q109861301 | Alzheimer's disease |
| Q29892262 | Alzheimer's disease and miRNA effects |
| Q30225359 | Androgen receptor signaling pathway |
| Q29892230 | Angiogenesis |
| Q30225526 | Angiopoietin-like protein 8 regulatory pathway |
| Q29892216 | Apoptosis |
| Q30230816 | Apoptosis-related network due to altered Notch3 in ovarian cancer |
| Q30225495 | B cell receptor signaling pathway |
| Q30225415 | BDNF-TrkB signaling |
| Q30225496 | Brain-derived neurotrophic factor (BDNF) signaling pathway |
| Q54991093 | Breast cancer pathway |
| Q50400559 | Caloric restriction and aging |
| Q30151248 | Cardiac hypertrophic response |
| Q66104536 | Cell migration and invasion through p75NTR |
| Q30225529 | Chemokine signaling pathway |
| Q50400050 | Chromosomal and microsatellite instability in colorectal cancer |
| Q54989225 | Clear cell renal cell carcinoma pathways |
| Q30151296 | Copper homeostasis |
| Q30225489 | Corticotropin-releasing hormone signaling pathway |
| Q30231006 | DNA damage response (only ATM dependent) |
| Q30225560 | EGF/EGFR signaling pathway |
| Q102733920 | EGFR tyrosine kinase inhibitor resistance |
| Q30225580 | EPO receptor signaling |
| Q54989094 | Ebola virus pathway in host |
| Q30225532 | Embryonic stem cell pluripotency pathways |
| Q30225565 | Endochondral ossification |
| Q94668622 | Endochondral ossification with skeletal dysplasias |
| Q54989421 | Epithelial to mesenchymal transition in colorectal cancer |
| Q30230897 | ErbB signaling pathway |
| Q30231009 | Estrogen signaling pathway |
| Q30230820 | Extracellular vesicle-mediated signaling in recipient cells |
| Q30225425 | Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling |
| Q50400546 | Fibrin complement receptor 3 signaling pathway |
| Q30151288 | Focal adhesion |
| Q30230865 | Focal adhesion: PI3K-Akt-mTOR-signaling pathway |
| Q30225467 | Follicle stimulating hormone (FSH) signaling pathway |
| Q109861037 | Fragile X syndrome |
| Q72082709 | Gastrin signaling pathway |
| Q29892275 | Glioblastoma signaling pathways |
| Q75747823 | Head and neck squamous cell carcinoma |
| Q67131122 | Hepatitis B infection |
| Q30230736 | Hepatitis C and hepatocellular carcinoma |
| Q89045284 | Host-pathogen interaction of human coronaviruses - apoptosis |
| Q30225457 | IL-1 signaling pathway |
| Q30225473 | IL-17 signaling pathway |
| Q30225569 | IL-2 signaling pathway |
| Q30151260 | IL-3 signaling pathway |
| Q30225540 | IL-4 signaling pathway |
| Q30225358 | IL-5 signaling pathway |
| Q30225404 | IL-6 signaling pathway |
| Q30225470 | IL-7 signaling pathway |
| Q30225566 | Insulin signaling |
| Q30225390 | Integrin-mediated cell adhesion |
| Q30225486 | Interleukin-11 signaling pathway |
| Q109860924 | Kallmann syndrome |
| Q102732586 | Kisspeptin/kisspeptin receptor system in the ovary |
| Q30151287 | Kit receptor signaling pathway |
| Q30225466 | Leptin signaling pathway |
| Q30230869 | Leptin-insulin signaling overlap |
| Q44011216 | Lipid metabolism pathway |
| Q29891990 | MAPK signaling pathway |
| Q29883414 | MECP2 and associated Rett syndrome |
| Q50400632 | MET in type 1 papillary renal cell carcinoma |
| Q109861217 | Malignant pleural mesothelioma |
| Q61996400 | Mammary gland development pathway - Embryonic development (Stage 1 of 4) |
| Q78271851 | Melanoma |
| Q30225381 | MicroRNAs in cardiomyocyte hypertrophy |
| Q30230780 | Microtubule cytoskeleton regulation |
| Q61996391 | Neovascularisation processes |
| Q84971596 | Netrin-UNC5B signaling pathway |
| Q63152061 | Neural crest cell migration during development |
| Q63153083 | Neural crest cell migration in cancer |
| Q109862431 | Neuroinflammation and glutamatergic signaling |
| Q54989956 | Non-small cell lung cancer |
| Q74069909 | Nonalcoholic fatty liver disease |
| Q61996544 | Notch signaling pathway (Netpath) |
| Q30225494 | Oncostatin M signaling pathway |
| Q30225421 | PI3K-AKT-mTOR signaling pathway and therapeutic opportunities |
| Q50400941 | PI3K-Akt signaling pathway |
| Q50400139 | PI3K/AKT/mTOR - VitD3 signaling |
| Q54990258 | Pancreatic adenocarcinoma pathway |
| Q30225405 | Pathways affected in adenoid cystic carcinoma |
| Q30225419 | Physico-chemical features and toxicity-associated pathways |
| Q30225514 | Primary focal segmental glomerulosclerosis (FSGS) |
| Q30225469 | Prolactin signaling pathway |
| Q30225450 | RAC1/PAK1/p38/MMP2 pathway |
| Q30225461 | RANKL/RANK signaling pathway |
| Q54989898 | Ras signaling |
| Q102743279 | Regucalcin in proximal tubule epithelial kidney cells |
| Q30230738 | Regulation of apoptosis by parathyroid hormone-related protein |
| Q30225368 | Regulation of toll-like receptor signaling pathway |
| Q75740366 | Relationship between inflammation, COX-2 and EGFR |
| Q61996417 | Resistin as a regulator of inflammation |
| Q30230801 | S1P receptor signal transduction |
| Q67132038 | Small cell lung cancer |
| Q50400720 | Somatroph axis (GH) and its relationship to dietary restriction and aging |
| Q30225458 | Sterol regulatory element-binding proteins (SREBP) signaling |
| Q62059922 | Synaptic signaling pathways associated with autism spectrum disorder |
| Q30225515 | T cell receptor and co-stimulatory signaling |
| Q30225430 | T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection |
| Q30230990 | T-cell receptor (TCR) signaling pathway |
| Q30225429 | TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition |
| Q30225411 | TGF-beta signaling pathway |
| Q30225482 | TNF-alpha signaling pathway |
| Q30225468 | TNF-related weak inducer of apoptosis (TWEAK) signaling pathway |
| Q30225369 | Target of rapamycin (TOR) signaling |
| Q50400152 | Thymic stromal lymphopoietin (TSLP) signaling pathway |
| Q30225464 | Thyroid stimulating hormone (TSH) signaling pathway |
| Q30231011 | Toll-like receptor signaling pathway |
| Q30231023 | Transcription factors regulate miRNAs related to cardiac hypertrophy |
| Q63151954 | Translation inhibitors in chronically activated PDGFRA cells |
| Q30225525 | VEGFA-VEGFR2 signaling pathway |
| Q30225399 | Wnt signaling pathway |
| Q30225410 | Wnt/beta-catenin signaling pathway in leukemia |
| Q44013044 | endometrial cancer |
| Q109863610 | modulators of TCR signaling and T cell activation |
| P11277 | CIViC gene ID | Wikidata property example | P1855 |
| Q101404954 | human luteal cell | has marker | P8872 |