F2RL1

protein-coding gene in the species Homo sapiens

DBpedia resource is: http://dbpedia.org/resource/Protease-activated_receptor_2

Abstract is: Protease activated receptor 2 (PAR2) also known as coagulation factor II (thrombin) receptor-like 1 (F2RL1) or G-protein coupled receptor 11 (GPR11) is a protein that in humans is encoded by the F2RL1 gene. PAR2 modulates inflammatory responses, obesity, metabolism, cancers and acts as a sensor for proteolytic enzymes generated during infection. In humans, we can find PAR2 in the stratum granulosum layer of epidermal keratinocytes. Functional PAR2 is also expressed by several immune cells such as eosinophils, neutrophils, monocytes, macrophages, dendritic cells, mast cells and T cells.

Wikimedia Commons category is Protease-activated receptor 2

F2RL1 is …

gene

protein-coding gene

External links are

P594	Ensembl gene ID	ENSG00000164251
P704	Ensembl transcript ID	ENST00000296677
		ENST00000514165
P351	Entrez Gene ID	2150
P2888	exact match	http://identifiers.org/ncbigene/2150
P646	Freebase ID	/m/03czfbr
P353	HGNC gene symbol	F2RL1
P354	HGNC ID	3538
P593	HomoloGene ID	21087
P6366	Microsoft Academic ID	125268873
P492	OMIM ID	600933
		600933
P10283	OpenAlex ID	C125268873
P638	PDB structure ID	5NDD
P639	RefSeq RNA ID	NM_005242
P2892	UMLS CUI	C1414506

P1057	chromosome	human chromosome 5	Q840741
P4196	cytogenetic location	5q13.3
P688	encodes	F2R like trypsin receptor 1	Q21115613
P5572	expressed in	duodenum	Q134955
		rectum	Q158716
		kidney tubule	Q11465565
		jejunal mucosa	Q30015772
		mucosa of ileum	Q66511085
		mucosa of transverse colon	Q66511199
		mucosa of sigmoid colon	Q66511227
		skin of thigh	Q66527052
		skin of hip	Q66535707
		gingival epithelium	Q66558726
P703	found in taxon	Homo sapiens	Q15978631
P645	genomic end	76131140
		76835315
P644	genomic start	76114758
		76818933
P684	ortholog	F2rl1	Q18250495
		F2rl1	Q24381293
		f2rl1.2	Q29767307
P2548	strand orientation	forward strand	Q22809680

Wikimedia Commons Images

P692: Gene Atlas image

FileName: PBB GE F2RL1 206429 at fs.png

Description: Gene expression pattern of the F2RL1 gene.

Artist: AndrewGNF at en.wikipedia

Work is copyrighted.
License: CC BY-SA 3.0
Attribution is required.

P692: Gene Atlas image

FileName: PBB GE F2RL1 213506 at fs.png

Description: Gene expression pattern of the F2RL1 gene.

Artist: AndrewGNF at English Wikipedia

Work is copyrighted.
License: CC BY-SA 3.0
Attribution is required.