Abstract is: Aspartate aminotransferase, mitochondrial is an enzyme that in humans is encoded by the GOT2 gene. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and Kreb's cycle. Also, GOT2 is a major participant in the malate-aspartate shuttle, which is a passage from the cytosol to the mitochondria. The two enzymes are homodimeric and show close homology. GOT2 has been seen to have a role in cell proliferation, especially in terms of tumor growth.
| P594 | Ensembl gene ID | ENSG00000125166 |
| P704 | Ensembl transcript ID | ENST00000245206 |
| ENST00000434819 | ||
| ENST00000492378 | ||
| ENST00000494627 | ||
| ENST00000496461 | ||
| ENST00000564400 | ||
| ENST00000568368 | ||
| P351 | Entrez Gene ID | 2806 |
| P2888 | exact match | http://identifiers.org/ncbigene/2806 |
| P646 | Freebase ID | /m/03gy518 |
| P353 | HGNC gene symbol | GOT2 |
| P354 | HGNC ID | 4433 |
| P593 | HomoloGene ID | 1572 |
| P6366 | Microsoft Academic ID | 2780410167 |
| P492 | OMIM ID | 138150 |
| 138150 | ||
| P639 | RefSeq RNA ID | NM_001286220 |
| NM_002080 | ||
| P2892 | UMLS CUI | C1415182 |
| P1057 | chromosome | human chromosome 16 | Q742870 |
| P4196 | cytogenetic location | 16q21 | |
| P688 | encodes | glutamic-oxaloacetic transaminase 2 | Q21116246 |
| P5572 | expressed in | gastrocnemius muscle | Q943203 |
| vastus lateralis muscle | Q975459 | ||
| triceps brachii muscle | Q83379 | ||
| apex of heart | Q66502809 | ||
| right auricle | Q66502834 | ||
| myocardium of left ventricle | Q66504996 | ||
| muscle of thigh | Q66514508 | ||
| right ventricle | Q1308310 | ||
| glutes | Q2478147 | ||
| middle temporal gyrus | Q5407200 | ||
| P703 | found in taxon | Homo sapiens | Q15978631 |
| P645 | genomic end | 58768261 | |
| 58734342 | |||
| P644 | genomic start | 58707131 | |
| 58741035 | |||
| P684 | ortholog | Got2 | Q29711825 |
| got2b | Q29758294 | ||
| got2a | Q29768331 | ||
| Got2 | Q18250905 | ||
| Got2 | Q24419975 | ||
| got-2.1 | Q29661287 | ||
| got-2.2 | Q29683683 | ||
| P2548 | strand orientation | reverse strand | Q22809711 |
FileName: PBB GE GOT2 200708 at fs.png
Description: Gene expression pattern of the GOT2 gene.
Artist: AndrewGNF at en.wikipedia
Work is copyrighted.
License: CC BY-SA 3.0
Attribution is required.
| Q21116246 | glutamic-oxaloacetic transaminase 2 | encoded by | P702 |
| GOT2 | wikipedia | |
| Persian (fa / Q9168) | GOT2 | wikipedia |
| GOT2 | wikipedia |
Search more.