Abstract is: Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha is an enzyme that in humans is encoded by the PPP2R3A gene.Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms.
P594 | Ensembl gene ID | ENSG00000073711 |
P704 | Ensembl transcript ID | ENST00000264977 |
ENST00000334546 | ||
ENST00000447251 | ||
ENST00000469270 | ||
ENST00000490467 | ||
P351 | Entrez Gene ID | 5523 |
P2888 | exact match | http://identifiers.org/ncbigene/5523 |
P646 | Freebase ID | /m/03gx722 |
P353 | HGNC gene symbol | PPP2R3A |
P354 | HGNC ID | 9307 |
P593 | HomoloGene ID | 20595 |
P492 | OMIM ID | 604944 |
604944 | ||
P639 | RefSeq RNA ID | NM_001190447 |
NM_002718 | ||
NM_181897 | ||
XM_006713686 | ||
XM_011512956 | ||
XM_017006787 | ||
XM_047448509 | ||
XM_047448510 | ||
XR_001740196 | ||
P2892 | UMLS CUI | C1418841 |
P1057 | chromosome | human chromosome 3 | Q668633 |
P4196 | cytogenetic location | 3q22.2-q22.3 | |
P688 | encodes | Protein phosphatase 2 regulatory subunit B''alpha | Q21118923 |
P5572 | expressed in | thoracic diaphragm | Q9654 |
vastus lateralis muscle | Q975459 | ||
glutes | Q2478147 | ||
triceps brachii muscle | Q83379 | ||
deltoid muscle | Q130243 | ||
biceps brachii | Q201363 | ||
myocardium of left ventricle | Q66504996 | ||
body of tongue | Q66544432 | ||
Skeletal muscle tissue of rectus abdominis | Q66601955 | ||
Skeletal muscle tissue of biceps brachii | Q66601980 | ||
P703 | found in taxon | Homo sapiens | Q15978631 |
P645 | genomic end | 135866733 | |
136147894 | |||
P644 | genomic start | 135684515 | |
135965728 | |||
P684 | ortholog | Ppp2r3a | Q18298461 |
Ppp2r3a | Q24365187 | ||
F43B10.1 | Q29692244 | ||
ppp2r3a | Q29778150 | ||
P2548 | strand orientation | forward strand | Q22809680 |
FileName: PBB GE PPP2R3A 207749 s at fs.png
Description: Gene expression pattern of the PPP2R3A gene.
Artist: AndrewGNF at English Wikipedia
Work is copyrighted.
License: CC BY-SA 3.0
Attribution is required.
FileName: PBB GE PPP2R3A 209632 at fs.png
Description: Gene expression pattern of the PPP2R3A gene.
Artist: AndrewGNF at en.wikipedia
Work is copyrighted.
License: CC BY-SA 3.0
Attribution is required.
FileName: PBB GE PPP2R3A 209633 at fs.png
Description: Gene expression pattern of the PPP2R3A gene.
Artist: AndrewGNF at en.wikipedia
Work is copyrighted.
License: CC BY-SA 3.0
Attribution is required.