PPP2R3A

protein-coding gene in the species Homo sapiens

DBpedia resource is: http://dbpedia.org/resource/PPP2R3A

Abstract is: Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha is an enzyme that in humans is encoded by the PPP2R3A gene.Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms.

PPP2R3A is …
instance of (P31):
geneQ7187

sublass of (P279):
protein-coding geneQ20747295

External links are
P594Ensembl gene IDENSG00000073711
P704Ensembl transcript IDENST00000264977
ENST00000334546
ENST00000447251
ENST00000469270
ENST00000490467
P351Entrez Gene ID5523
P2888exact matchhttp://identifiers.org/ncbigene/5523
P646Freebase ID/m/03gx722
P353HGNC gene symbolPPP2R3A
P354HGNC ID9307
P593HomoloGene ID20595
P492OMIM ID604944
604944
P639RefSeq RNA IDNM_001190447
NM_002718
NM_181897
XM_006713686
XM_011512956
XM_017006787
XM_047448509
XM_047448510
XR_001740196
P2892UMLS CUIC1418841

P1057chromosomehuman chromosome 3Q668633
P4196cytogenetic location3q22.2-q22.3
P688encodesProtein phosphatase 2 regulatory subunit B''alphaQ21118923
P5572expressed inthoracic diaphragmQ9654
vastus lateralis muscleQ975459
glutesQ2478147
triceps brachii muscleQ83379
deltoid muscleQ130243
biceps brachiiQ201363
myocardium of left ventricleQ66504996
body of tongueQ66544432
Skeletal muscle tissue of rectus abdominisQ66601955
Skeletal muscle tissue of biceps brachiiQ66601980
P703found in taxonHomo sapiensQ15978631
P645genomic end135866733
136147894
P644genomic start135684515
135965728
P684orthologPpp2r3aQ18298461
Ppp2r3aQ24365187
F43B10.1Q29692244
ppp2r3aQ29778150
P2548strand orientationforward strandQ22809680

Wikimedia Commons Images

P692: Gene Atlas image


FileName: PBB GE PPP2R3A 207749 s at fs.png

Description: Gene expression pattern of the PPP2R3A gene.

Artist: AndrewGNF at English Wikipedia

Work is copyrighted.
License: CC BY-SA 3.0
Attribution is required.

P692: Gene Atlas image


FileName: PBB GE PPP2R3A 209632 at fs.png

Description: Gene expression pattern of the PPP2R3A gene.

Artist: AndrewGNF at en.wikipedia

Work is copyrighted.
License: CC BY-SA 3.0
Attribution is required.

P692: Gene Atlas image


FileName: PBB GE PPP2R3A 209633 at fs.png

Description: Gene expression pattern of the PPP2R3A gene.

Artist: AndrewGNF at en.wikipedia

Work is copyrighted.
License: CC BY-SA 3.0
Attribution is required.