IRS4

protein-coding gene in the species Homo sapiens

DBpedia resource is: http://dbpedia.org/resource/IRS4

Abstract is: Insulin receptor substrate 4 is a protein that in humans is encoded by the IRS4 gene. IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.

IRS4 is …
instance of (P31):
geneQ7187

sublass of (P279):
protein-coding geneQ20747295

External links are
P594Ensembl gene IDENSG00000133124
P704Ensembl transcript IDENST00000372129
ENST00000564206
P351Entrez Gene ID8471
P2888exact matchhttp://identifiers.org/ncbigene/8471
P646Freebase ID/m/02kfgt2
P353HGNC gene symbolIRS4
P354HGNC ID6128
P593HomoloGene ID136777
P492OMIM ID300904
300904
P639RefSeq RNA IDNM_001379150
NM_003604
XM_006724713
XM_011531061
P2892UMLS CUIC1334142

P1057chromosomehuman X chromosomeQ29867336
P4196cytogenetic locationXq22.3
P688encodesInsulin receptor substrate 4Q21172382
P5572expressed inovaryQ9631
hypothalamusQ164386
pituitary glandQ156871
cervixQ666412
anterior pituitaryQ356002
gastric mucosaQ383249
right ovaryQ66502831
left ovaryQ66502832
right lobe of thyroid glandQ66508047
body of uterusQ66508550
P703found in taxonHomo sapiensQ15978631
P645genomic end107979651
108736563
P644genomic start107975712
108719946
P684orthologIrs4Q18251687
P2548strand orientationreverse strandQ22809711

Wikimedia Commons Images

P692: Gene Atlas image


FileName: PBB GE IRS4 207403 at fs.png

Description: Gene expression pattern of the IRS4 gene.

Artist: AndrewGNF at en.wikipedia

Work is copyrighted.
License: CC BY-SA 3.0
Attribution is required.

Reverse relations

regulates (molecular biology) (P128)
Q21414101hsa-let-7b-5p
Q27594034hsa-let-7e-5p
Q27593173hsa-miR-125b-5p
Q27593305hsa-miR-16-5p
Q27593326hsa-miR-18a-3p
Q27593325hsa-miR-18a-5p
Q27594484hsa-miR-191-5p
Q27593625hsa-miR-193b-3p
Q27593815hsa-miR-21-3p
Q27595203hsa-miR-222-3p
Q27594002hsa-miR-330-5p
Q27593246hsa-miR-331-3p
Q27593906hsa-miR-3591-3p
Q27593639hsa-miR-484
Q27595302hsa-miR-505-3p
Q27593210hsa-miR-615-3p
Q27595260hsa-miR-652-3p
Q27593716hsa-miR-744-5p

has part(s) (P527)
Q30231044Adipogenesis
Q109861301Alzheimer's disease
Q29892262Alzheimer's disease and miRNA effects
Q30225526Angiopoietin-like protein 8 regulatory pathway
Q30230865Focal adhesion: PI3K-Akt-mTOR-signaling pathway
Q30225566Insulin signaling
Q30230869Leptin-insulin signaling overlap

Q18251687Irs4orthologP684
Q21172382Insulin receptor substrate 4encoded byP702

The articles in Wikimedia projects and languages

      IRS4wikipedia
      IRS4wikipedia
Tatar language (tt / Q25285)IRS4wikipedia
      IRS4wikipedia

Search more.