PEA15

protein-coding gene in the species Homo sapiens

DBpedia resource is: http://dbpedia.org/resource/PEA15

Abstract is: Astrocytic phosphoprotein PEA-15 is a protein that in humans is encoded by the PEA15 gene. PEA15 is a death effector domain (DED)-containing protein predominantly expressed in the central nervous system, particularly in astrocytes. PEA-15 promotes autophagy in glioma cells in a JNK-dependent manner.

PEA15 is …
instance of (P31):
geneQ7187

sublass of (P279):
protein-coding geneQ20747295

External links are
P594Ensembl gene IDENSG00000162734
P704Ensembl transcript IDENST00000360472
ENST00000368076
ENST00000368077
ENST00000488858
P351Entrez Gene ID8682
P2888exact matchhttp://identifiers.org/ncbigene/8682
P646Freebase ID/m/02kfh5j
P353HGNC gene symbolPEA15
P354HGNC ID8822
P593HomoloGene ID7884
P492OMIM ID603434
603434
P639RefSeq RNA IDNM_001297576
NM_001297577
NM_001297578
NM_003768
NR_123724
XM_047433391
P2892UMLS CUIC1418449

P1057chromosomehuman chromosome 1Q430258
P4196cytogenetic location1q23.2
P688encodesProliferation and apoptosis adaptor protein 15Q21120426
Phosphoprotein enriched in astrocytes 15, isoform CRA_aQ21141174
P5572expressed inspinal cordQ9606
subthalamic nucleusQ2270424
inferior olivary nucleusQ5620438
inferior ganglion of vagus nerveQ6029330
external globus pallidusQ6495612
pars reticulataQ7139918
superior vestibular nucleusQ11731926
dorsal motor nucleus of vagus nerveQ66544400
C1 segmentQ66569011
internal globus pallidusQ17132761
P703found in taxonHomo sapiensQ15978631
P645genomic end160185166
160215376
P644genomic start160175127
160205380
P684orthologPea15Q24406758
pea15Q29777730
Pea15aQ18252968
P2548strand orientationforward strandQ22809680

Wikimedia Commons Images

P692: Gene Atlas image


FileName: PBB GE PEA15 200787 s at fs.png

Description: Gene expression pattern of the PEA15 gene.

Artist: AndrewGNF at en.wikipedia

Work is copyrighted.
License: CC BY-SA 3.0
Attribution is required.

P692: Gene Atlas image


FileName: PBB GE PEA15 200788 s at fs.png

Description: Gene expression pattern of the PEA15 gene.

Artist: AndrewGNF at en.wikipedia

Work is copyrighted.
License: CC BY-SA 3.0
Attribution is required.

Reverse relations

regulates (molecular biology) (P128)
Q27595285hsa-miR-106a-5p
Q27594907hsa-miR-106b-5p
Q27593903hsa-miR-122-5p
Q27594562hsa-miR-1224-3p
Q27594338hsa-miR-124-3p
Q27594383hsa-miR-1306-5p
Q27594358hsa-miR-155-5p
Q27593323hsa-miR-17-5p
Q27593329hsa-miR-20a-5p
Q27595281hsa-miR-20b-5p
Q27593694hsa-miR-212-3p
Q27592721hsa-miR-34a-5p
Q27594902hsa-miR-3609
Q27595104hsa-miR-3651
Q27594445hsa-miR-3667-3p
Q27594874hsa-miR-3943
Q27593997hsa-miR-4323
Q27593126hsa-miR-4691-5p
Q27594525hsa-miR-4796-3p
Q27593402hsa-miR-493-3p
Q27593590hsa-miR-5009-3p
Q27594489hsa-miR-5193
Q27594081hsa-miR-519d-3p
Q27594059hsa-miR-526b-3p
Q27594609hsa-miR-548ah-5p
Q27595220hsa-miR-660-3p
Q27593111hsa-miR-6749-3p
Q27593621hsa-miR-6769a-3p
Q27593939hsa-miR-6792-3p
Q27594769hsa-miR-877-3p
Q27594905hsa-miR-93-5p

ortholog (P684)
Q24406758Pea15
Q18252968Pea15a
Q29777730pea15

encoded by (P702)
Q21141174Phosphoprotein enriched in astrocytes 15, isoform CRA_a
Q21120426Proliferation and apoptosis adaptor protein 15

Q30225388Apoptosis modulation and signalinghas part(s)P527