Abstract is: Interferon-induced transmembrane protein 3 (IFITM3) is a protein that in humans is encoded by the IFITM3 gene. It plays a critical role in the immune system's defense against Swine Flu, where heightened levels of IFITM3 keep viral levels low, and the removal of IFITM3 allows the virus to multiply unchecked. This observation has been further advanced by a recent study from Paul Kellam's lab that shows that a single nucleotide polymorphism in the human IFITM3 gene purported to increase influenza susceptibility is overrepresented in people hospitalised with pandemic H1N1. The prevalence of this mutation is thought to be approximately 1/400 in European populations.
| P594 | Ensembl gene ID | ENSG00000142089 |
| P704 | Ensembl transcript ID | ENST00000399808 |
| ENST00000526811 | ||
| ENST00000531688 | ||
| ENST00000602735 | ||
| ENST00000602809 | ||
| ENST00000602949 | ||
| ENST00000679382 | ||
| ENST00000679433 | ||
| ENST00000679441 | ||
| ENST00000679746 | ||
| ENST00000679792 | ||
| ENST00000679793 | ||
| ENST00000679830 | ||
| ENST00000680023 | ||
| ENST00000680209 | ||
| ENST00000680372 | ||
| ENST00000680622 | ||
| ENST00000680716 | ||
| ENST00000680720 | ||
| ENST00000680920 | ||
| ENST00000680932 | ||
| ENST00000681048 | ||
| ENST00000681184 | ||
| ENST00000681198 | ||
| ENST00000681304 | ||
| ENST00000681748 | ||
| ENST00000681840 | ||
| P351 | Entrez Gene ID | 10410 |
| P2888 | exact match | http://identifiers.org/ncbigene/10410 |
| P646 | Freebase ID | /m/03hl3r4 |
| P353 | HGNC gene symbol | IFITM3 |
| P354 | HGNC ID | 5414 |
| P593 | HomoloGene ID | 136199 |
| P6366 | Microsoft Academic ID | 2911029346 |
| P492 | OMIM ID | 605579 |
| 605579 | ||
| P639 | RefSeq RNA ID | NM_021034 |
| NR_049759 | ||
| P2892 | UMLS CUI | C1415898 |
| P1057 | chromosome | human chromosome 11 | Q847096 |
| P4196 | cytogenetic location | 11p15.5 | |
| P688 | encodes | Interferon induced transmembrane protein 3 | Q21131531 |
| P5572 | expressed in | right coronary artery | Q429285 |
| left coronary artery | Q744391 | ||
| canal of the cervix | Q785307 | ||
| ascending aorta | Q2349469 | ||
| right lung | Q5938041 | ||
| upper lobe of left lung | Q28656761 | ||
| body of uterus | Q66508550 | ||
| left uterine tube | Q66509809 | ||
| Descending thoracic aorta | Q66592966 | ||
| pericardium | Q193302 | ||
| P703 | found in taxon | Homo sapiens | Q15978631 |
| P645 | genomic end | 327537 | |
| 329475 | |||
| P644 | genomic start | 319676 | |
| 319669 | |||
| P5008 | on focus list of Wikimedia project | WikiProject Zika Corpus | Q54439832 |
| P684 | ortholog | Ifitm3 | Q18261608 |
| Ifitm3 | Q24405603 | ||
| P2548 | strand orientation | reverse strand | Q22809711 |
| Q89269875 | Host-pathogen interaction of human coronaviruses - MAPK signaling |
| Q109863844 | Network map of SARS-CoV-2 signaling pathway |
| Q21131531 | Interferon induced transmembrane protein 3 | encoded by | P702 |
| Q101405036 | human monocyte | has marker | P8872 |
| Q24367663 | The IFITMs Inhibit Zika Virus Replication | main subject | P921 |
| IFITM3 | wikipedia | |
| IFITM3 | wikipedia | |
| IFITM3 | wikipedia | |
| IFITM3 | wikipedia | |
| Tatar language (tt / Q25285) | IFITM3 | wikipedia |
| IFITM3 | wikipedia |
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