GSK3B

protein-coding gene in the species Homo sapiens

DBpedia resource is: http://dbpedia.org/resource/Glycogen_synthase_kinase-3_beta

Abstract is: Glycogen synthase kinase-3 beta, (GSK-3 beta), is an enzyme that in humans is encoded by the GSK3B gene. In mice, the enzyme is encoded by the Gsk3b gene. Abnormal regulation and expression of GSK-3 beta is associated with an increased susceptibility towards bipolar disorder.

GSK3B is …
instance of (P31):
geneQ7187

sublass of (P279):
protein-coding geneQ20747295

External links are
P594Ensembl gene IDENSG00000082701
P704Ensembl transcript IDENST00000264235
ENST00000316626
ENST00000473886
ENST00000474830
ENST00000650344
ENST00000676566
ENST00000676650
ENST00000676722
ENST00000676723
ENST00000676733
ENST00000676743
ENST00000676775
ENST00000676844
ENST00000676887
ENST00000676890
ENST00000676910
ENST00000676948
ENST00000677034
ENST00000677046
ENST00000677067
ENST00000677069
ENST00000677128
ENST00000677169
ENST00000677338
ENST00000677362
ENST00000677400
ENST00000677423
ENST00000677483
ENST00000677502
ENST00000677530
ENST00000677648
ENST00000677716
ENST00000677788
ENST00000677804
ENST00000677870
ENST00000677875
ENST00000677878
ENST00000677885
ENST00000677903
ENST00000677959
ENST00000677995
ENST00000678013
ENST00000678064
ENST00000678121
ENST00000678159
ENST00000678181
ENST00000678210
ENST00000678245
ENST00000678286
ENST00000678342
ENST00000678350
ENST00000678377
ENST00000678439
ENST00000678509
ENST00000678561
ENST00000678608
ENST00000678678
ENST00000678754
ENST00000678787
ENST00000678967
ENST00000679066
ENST00000679068
ENST00000679085
ENST00000679131
ENST00000679164
ENST00000679188
ENST00000679194
ENST00000679201
ENST00000679206
P351Entrez Gene ID2932
P2888exact matchhttp://identifiers.org/ncbigene/2932
P646Freebase ID/m/03cpy9m
P353HGNC gene symbolGSK3B
P354HGNC ID4617
P593HomoloGene ID55629
P6366Microsoft Academic ID2910439697
P492OMIM ID605004
605004
P10283OpenAlex IDC104629339
P639RefSeq RNA IDNM_001146156
NM_001354596
NM_002093
XM_006713610
P2892UMLS CUIC1415321

P1057chromosomehuman chromosome 3Q668633
P4196cytogenetic location3q13.33
P688encodesglycogen synthase kinase 3 betaQ5514576
P5572expressed inAchilles tendonQ223172
postcentral gyrusQ956517
ganglionic eminenceQ4133185
sural nerveQ6135922
ventricular zoneQ28455175
right testisQ66502829
left testisQ66502830
skin of thighQ66527052
epithelium of colonQ66714209
buccal mucosa cellQ116529247
P703found in taxonHomo sapiensQ15978631
P645genomic end119813264
120094994
P644genomic start119540170
119821321
P684orthologGsk3bQ21518808
Gsk3bQ24383785
gsk-3Q29685492
gsk3baQ29772805
P2548strand orientationreverse strandQ22809711

Wikimedia Commons Images

P18: image


FileName: Protein GSK3B PDB 1gng.png

Description: Structure of the GSK3B protein. Based on PyMOL rendering of PDB 1gng.

Artist: Emw

Work is copyrighted.
License: CC BY-SA 3.0
Attribution is required.

P692: Gene Atlas image


FileName: PBB GE GSK3B 209945 s at fs.png

Description: Gene expression pattern of the GSK3B gene.

Artist: AndrewGNF at English Wikipedia

Work is copyrighted.
License: CC BY-SA 3.0
Attribution is required.

Reverse relations

regulates (molecular biology) (P128)
Q27594437hsa-let-7a-3p
Q27594441hsa-let-7b-3p
Q27595112hsa-let-7f-1-3p
Q27595232hsa-let-7f-2-3p
Q27593451hsa-miR-1185-1-3p
Q27593452hsa-miR-1185-2-3p
Q27595273hsa-miR-1277-5p
Q27593313hsa-miR-1297
Q27594358hsa-miR-155-5p
Q27593307hsa-miR-15a-5p
Q27594548hsa-miR-15b-5p
Q27593305hsa-miR-16-5p
Q27594926hsa-miR-182-5p
Q27594930hsa-miR-183-5p
Q27593552hsa-miR-190a-3p
Q27593679hsa-miR-1910-5p
Q27593706hsa-miR-195-5p
Q27592872hsa-miR-199a-5p
Q27593222hsa-miR-26a-5p
Q27592900hsa-miR-29b-3p
Q27593850hsa-miR-3065-3p
Q27594429hsa-miR-33a-3p
Q27592984hsa-miR-346
Q27594234hsa-miR-3606-3p
Q27593489hsa-miR-369-3p
Q27595249hsa-miR-374a-5p
Q27595242hsa-miR-374b-5p
Q27593480hsa-miR-377-3p
Q27594972hsa-miR-383-3p
Q27593484hsa-miR-409-3p
Q27593483hsa-miR-409-5p
Q27593490hsa-miR-410-3p
Q27594482hsa-miR-425-5p
Q27594836hsa-miR-4465
Q27594822hsa-miR-4643
Q27594557hsa-miR-4789-5p
Q27593907hsa-miR-5011-5p
Q27595318hsa-miR-513a-3p
Q27595314hsa-miR-513c-3p
Q27593229hsa-miR-548c-3p
Q27594762hsa-miR-5683
Q27594372hsa-miR-5692b
Q27594709hsa-miR-5692c
Q27592723hsa-miR-5697
Q27594533hsa-miR-6083
Q27593862hsa-miR-6787-3p
Q27594500hsa-miR-8064
Q27594154hsa-miR-8485
Q27594769hsa-miR-877-3p
Q27593334hsa-miR-92a-3p
Q27594928hsa-miR-96-5p
Q27595231hsa-miR-98-3p

has part(s) (P527)
Q84972217Acute viral myocarditis
Q109861301Alzheimer's disease
Q29892262Alzheimer's disease and miRNA effects
Q30225359Androgen receptor signaling pathway
Q30225526Angiopoietin-like protein 8 regulatory pathway
Q30225495B cell receptor signaling pathway
Q30225496Brain-derived neurotrophic factor (BDNF) signaling pathway
Q54991093Breast cancer pathway
Q30151248Cardiac hypertrophic response
Q30102240Cardiac progenitor differentiation
Q29892200Cell cycle
Q30225529Chemokine signaling pathway
Q50400050Chromosomal and microsatellite instability in colorectal cancer
Q30230834Circadian rhythm genes
Q30151296Copper homeostasis
Q30225489Corticotropin-releasing hormone signaling pathway
Q30231006DNA damage response (only ATM dependent)
Q102733920EGFR tyrosine kinase inhibitor resistance
Q30225532Embryonic stem cell pluripotency pathways
Q54989421Epithelial to mesenchymal transition in colorectal cancer
Q30230897ErbB signaling pathway
Q30225425Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling
Q30151288Focal adhesion
Q30230865Focal adhesion: PI3K-Akt-mTOR-signaling pathway
Q72082709Gastrin signaling pathway
Q30230918Glycogen synthesis and degradation
Q30225473IL-17 signaling pathway
Q102744190IL-18 signaling pathway
Q30225358IL-5 signaling pathway
Q30225404IL-6 signaling pathway
Q30225470IL-7 signaling pathway
Q102716977Influence of laminopathies on Wnt signaling
Q30225566Insulin signaling
Q30225466Leptin signaling pathway
Q102719481MAP3K1 role in promoting and blocking gonadal determination
Q109861217Malignant pleural mesothelioma
Q30225381MicroRNAs in cardiomyocyte hypertrophy
Q30230780Microtubule cytoskeleton regulation
Q59829224NRF2-ARE regulation
Q29891995Neural crest differentiation
Q74069909Nonalcoholic fatty liver disease
Q61996544Notch signaling pathway (Netpath)
Q104857857Overlap between signal transduction pathways contributing to LMNA laminopathies
Q30225421PI3K-AKT-mTOR signaling pathway and therapeutic opportunities
Q50400941PI3K-Akt signaling pathway
Q50400139PI3K/AKT/mTOR - VitD3 signaling
Q30225419Physico-chemical features and toxicity-associated pathways
Q30225469Prolactin signaling pathway
Q30225412Regulation of Wnt / B-catenin signaling by small molecule compounds
Q30230738Regulation of apoptosis by parathyroid hormone-related protein
Q30230984Senescence and autophagy in cancer
Q62059922Synaptic signaling pathways associated with autism spectrum disorder
Q30225515T cell receptor and co-stimulatory signaling
Q107363266T-cell activation SARS-CoV-2
Q30225430T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection
Q30225468TNF-related weak inducer of apoptosis (TWEAK) signaling pathway
Q102742382Thyroid hormones production and peripheral downstream signaling effects
Q30225525VEGFA-VEGFR2 signaling pathway
Q30225555Wnt signaling
Q30225399Wnt signaling pathway
Q30225546Wnt signaling pathway and pluripotency
Q30225410Wnt/beta-catenin signaling pathway in leukemia
Q44013044endometrial cancer
Q30225378energy metabolism
Q54989478lncRNA in canonical Wnt signaling and colorectal cancer
Q28922670melatonin metabolism and effects
Q44017754miRNA regulation of prostate cancer signaling pathways
Q56856314ncRNAs involved in Wnt signaling in hepatocellular carcinoma

ortholog (P684)
Q21518808Gsk3b
Q24383785Gsk3b
Q29685492gsk-3
Q29772805gsk3ba

Q5514576glycogen synthase kinase 3 betaencoded byP702
Q115212924Metabolic Contributions of Wnt Signaling: More Than Controlling Flightmain subjectP921

The articles in Wikimedia projects and languages

cyGSK3Bwikipedia
      Glycogen synthase kinase-3 betawikipedia
      Kinaza glikogen sintaze-3 betawikipedia
      GSK-3βwikipedia
      GSK3Bwikipedia
      GSK3Bwikipedia
Tatar language (tt / Q25285)GSK3Bwikipedia
      GSK3Bwikipedia

Search more.