Abstract is: Apolipoprotein C-I is a protein component of lipoproteins that in humans is encoded by the APOC1 gene.
protein | Q8054 |
P705 | Ensembl protein ID | ENSP00000465190 |
ENSP00000465356 | ||
ENSP00000465710 | ||
ENSP00000466146 | ||
ENSP00000466227 | ||
ENSP00000467368 | ||
ENSP00000467504 | ||
ENSP00000468029 | ||
ENSP00000468276 | ||
P2888 | exact match | http://purl.uniprot.org/uniprot/P02654 |
https://identifiers.org/uniprot:P02654 | ||
https://www.ncbi.nlm.nih.gov/protein/P02654 | ||
P646 | Freebase ID | /m/0d_f1w |
P638 | PDB structure ID | 1ALE |
1ALF | ||
1IOJ | ||
1OPP | ||
P637 | RefSeq protein ID | NP_001307994 |
NP_001307995 | ||
NP_001366616 | ||
NP_001636 | ||
P352 | UniProt protein ID | P02654 |
P682 | biological process | chylomicron remnant clearance | Q14890403 |
very-low-density lipoprotein particle clearance | Q14890413 | ||
very-low-density lipoprotein particle assembly | Q14890595 | ||
negative regulation of phosphatidylcholine catabolic process | Q14904543 | ||
negative regulation of very-low-density lipoprotein particle clearance | Q14904544 | ||
regulation of cholesterol transport | Q14904545 | ||
negative regulation of cholesterol transport | Q14904546 | ||
plasma lipoprotein particle remodeling | Q14904547 | ||
negative regulation of lipid metabolic process | Q14904548 | ||
negative regulation of lipoprotein lipase activity | Q14904549 | ||
lipid metabolism | Q2792936 | ||
cholesterol metabolic process | Q14599650 | ||
negative regulation of lipid catabolic process | Q14761966 | ||
triglyceride metabolic process | Q14819245 | ||
positive regulation of cholesterol esterification | Q14859613 | ||
negative regulation of fatty acid biosynthetic process | Q14860457 | ||
positive regulation of catalytic activity | Q14863412 | ||
lipoprotein metabolic process | Q14864753 | ||
negative regulation of receptor-mediated endocytosis | Q14865048 | ||
lipid transport | Q14872727 | ||
high-density lipoprotein particle remodeling | Q14878188 | ||
cholesterol efflux | Q14890389 | ||
phospholipid efflux | Q14890392 | ||
P681 | cell component | endoplasmic reticulum | Q79927 |
chylomicron | Q423126 | ||
extracellular region | Q14645596 | ||
very-low-density lipoprotein particle | Q14864742 | ||
high-density lipoprotein particle | Q14878180 | ||
P702 | encoded by | APOC1 | Q14904550 |
P703 | found in taxon | Homo sapiens | Q15978631 |
P680 | molecular function | phospholipase inhibitor activity | Q14904531 |
lipase inhibitor activity | Q14904537 | ||
fatty acid binding | Q14860851 | ||
phosphatidylcholine binding | Q14878186 | ||
phosphatidylcholine-sterol O-acyltransferase activator activity | Q14890337 | ||
P361 | part of | apolipoprotein C-I | Q24773331 |
Q100162873 | Expression of APOC1 regulated by NR1H2 or NR1H3 |
Q50274720 | VLDL [extracellular region] |
Q50299728 | VLDL binds APOC1 and APOC4 |
Q24299929 | Apolipoprotein C-1 inhibits the hydrolysis by phospholipase A2 of phospholipids in liposomes and cell membranes |
Q24299172 | Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification |
Q24312753 | Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo |
Q24290771 | Apolipoprotein specificity for lipid efflux by the human ABCAI transporter |
Q24310834 | Effect of serum and C-apoproteins from very low density lipoproteins on human postheparin plasma hepatic lipase |
Q24293750 | Exact localization of the familial dysbetalipoproteinemia associated HpaI restriction site in the promoter region of the APOC1 gene |
Q24290207 | Human apolipoprotein C-I accounts for the ability of plasma high density lipoproteins to inhibit the cholesteryl ester transfer protein activity |
Q24300330 | Inhibitory effects of C apolipoproteins from rats and humans on the uptake of triglyceride-rich lipoproteins and their remnants by the perfused rat liver |
Q24323234 | Mechanisms of inhibition by apolipoprotein C of apolipoprotein E-dependent cellular metabolism of human triglyceride-rich lipoproteins through the low density lipoprotein receptor pathway |
Q24319030 | Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL |
Q14904550 | APOC1 | encodes | P688 |
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