Apolipoprotein C1

mammalian protein found in Homo sapiens

DBpedia resource is: http://dbpedia.org/resource/Apolipoprotein_C-I

Abstract is: Apolipoprotein C-I is a protein component of lipoproteins that in humans is encoded by the APOC1 gene.

Apolipoprotein C1 is …
instance of (P31):
proteinQ8054

External links are
P705Ensembl protein IDENSP00000465190
ENSP00000465356
ENSP00000465710
ENSP00000466146
ENSP00000466227
ENSP00000467368
ENSP00000467504
ENSP00000468029
ENSP00000468276
P2888exact matchhttp://purl.uniprot.org/uniprot/P02654
https://identifiers.org/uniprot:P02654
https://www.ncbi.nlm.nih.gov/protein/P02654
P646Freebase ID/m/0d_f1w
P638PDB structure ID1ALE
1ALF
1IOJ
1OPP
P637RefSeq protein IDNP_001307994
NP_001307995
NP_001366616
NP_001636
P352UniProt protein IDP02654

P682biological processchylomicron remnant clearanceQ14890403
very-low-density lipoprotein particle clearanceQ14890413
very-low-density lipoprotein particle assemblyQ14890595
negative regulation of phosphatidylcholine catabolic processQ14904543
negative regulation of very-low-density lipoprotein particle clearanceQ14904544
regulation of cholesterol transportQ14904545
negative regulation of cholesterol transportQ14904546
plasma lipoprotein particle remodelingQ14904547
negative regulation of lipid metabolic processQ14904548
negative regulation of lipoprotein lipase activityQ14904549
lipid metabolismQ2792936
cholesterol metabolic processQ14599650
negative regulation of lipid catabolic processQ14761966
triglyceride metabolic processQ14819245
positive regulation of cholesterol esterificationQ14859613
negative regulation of fatty acid biosynthetic processQ14860457
positive regulation of catalytic activityQ14863412
lipoprotein metabolic processQ14864753
negative regulation of receptor-mediated endocytosisQ14865048
lipid transportQ14872727
high-density lipoprotein particle remodelingQ14878188
cholesterol effluxQ14890389
phospholipid effluxQ14890392
P681cell componentendoplasmic reticulumQ79927
chylomicronQ423126
extracellular regionQ14645596
very-low-density lipoprotein particleQ14864742
high-density lipoprotein particleQ14878180
P702encoded byAPOC1Q14904550
P703found in taxonHomo sapiensQ15978631
P680molecular functionphospholipase inhibitor activityQ14904531
lipase inhibitor activityQ14904537
fatty acid bindingQ14860851
phosphatidylcholine bindingQ14878186
phosphatidylcholine-sterol O-acyltransferase activator activityQ14890337
P361part ofapolipoprotein C-IQ24773331

Reverse relations

has part(s) (P527)
Q100162873Expression of APOC1 regulated by NR1H2 or NR1H3
Q50274720VLDL [extracellular region]
Q50299728VLDL binds APOC1 and APOC4

main subject (P921)
Q24299929Apolipoprotein C-1 inhibits the hydrolysis by phospholipase A2 of phospholipids in liposomes and cell membranes
Q24299172Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification
Q24312753Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo
Q24290771Apolipoprotein specificity for lipid efflux by the human ABCAI transporter
Q24310834Effect of serum and C-apoproteins from very low density lipoproteins on human postheparin plasma hepatic lipase
Q24293750Exact localization of the familial dysbetalipoproteinemia associated HpaI restriction site in the promoter region of the APOC1 gene
Q24290207Human apolipoprotein C-I accounts for the ability of plasma high density lipoproteins to inhibit the cholesteryl ester transfer protein activity
Q24300330Inhibitory effects of C apolipoproteins from rats and humans on the uptake of triglyceride-rich lipoproteins and their remnants by the perfused rat liver
Q24323234Mechanisms of inhibition by apolipoprotein C of apolipoprotein E-dependent cellular metabolism of human triglyceride-rich lipoproteins through the low density lipoprotein receptor pathway
Q24319030Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL

Q14904550APOC1encodesP688

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