GK

protein-coding gene in the species Homo sapiens

DBpedia resource is: http://dbpedia.org/resource/Glycerol_kinase

Abstract is: Glycerol kinase, encoded by the gene GK, is a phosphotransferase enzyme involved in triglycerides and glycerophospholipids synthesis. Glycerol kinase catalyzes the transfer of a phosphate from ATP to glycerol thus forming glycerol 3-phosphate: ATP + glycerol <=> ADP + sn-glycerol 3-phosphate Adipocytes lack glycerol kinase so they cannot metabolize the glycerol produced during triacyl glycerol degradation. This glycerol is instead shuttled to the liver via the blood where it is: * Phosphorylated by glycerol kinase to glycerol 3-phosphate. * Converted from glycerol 3-phosphate to dihydroxyacetone phosphate (DHAP) via glycerol 3-phosphate dehydrogenase. DHAP can participate in glycolysis or gluconeogenesis.

GK is …
instance of (P31):
geneQ7187

sublass of (P279):
protein-coding geneQ20747295

External links are
P594Ensembl gene IDENSG00000198814
P704Ensembl transcript IDENST00000378938
ENST00000378941
ENST00000378943
ENST00000378945
ENST00000378946
ENST00000427190
ENST00000471362
ENST00000479048
ENST00000481024
ENST00000487652
ENST00000488296
ENST00000692461
P351Entrez Gene ID2710
P2888exact matchhttp://identifiers.org/ncbigene/2710
P646Freebase ID/m/02pr70m
P353HGNC gene symbolGK
P354HGNC ID4289
P593HomoloGene ID21848
P492OMIM ID300474
300474
P639RefSeq RNA IDNM_000167
NM_001128127
NM_001205019
NM_001399987
NM_203391
NR_174369
NR_174370
NR_174371
NR_174372
NR_174373
NR_174374
NR_174375
XM_006724483
XM_011545491
XM_011545492
P2892UMLS CUIC1415082

P1057chromosomehuman X chromosomeQ29867336
P4196cytogenetic locationXp21.2
P688encodesGlycerol kinaseQ21173596
P5572expressed inbloodQ7873
monocyteQ107244
right lobe of liverQ6493472
kidney tubuleQ11465565
duodenumQ134955
jejunal mucosaQ30015772
nasal epitheliumQ66559633
stromal cell of endometriumQ66592424
human kidneyQ112107043
buccal mucosa cellQ116529247
P703found in taxonHomo sapiensQ15978631
P645genomic end30748725
30731462
P644genomic start30671476
30653359
P684orthologGykl1Q18250841
GkQ18251037
Gykl1Q24419509
GkQ24420159
GUT1Q27544761
R11F4.1Q29705247
Gk2Q29710306
zgc:172295Q29747984
P2548strand orientationforward strandQ22809680

Reverse relations

regulates (molecular biology) (P128)
Q27594217hsa-miR-10b-5p
Q27593693hsa-miR-132-3p

has part(s) (P527)
Q30230913Triacylglyceride synthesis
Q30225382Type II diabetes mellitus
Q28031228fatty acid beta-oxidation

ortholog (P684)
Q27544761GUT1
Q18251037Gk
Q24420159Gk
Q29710306Gk2
Q18250841Gykl1
Q24419509Gykl1
Q29705247R11F4.1
Q29747984zgc:172295

Q5572555glycerol kinase deficiencygenetic associationP2293
Q21173596Glycerol kinaseencoded byP702

The articles in Wikimedia projects and languages

Tatar language (tt / Q25285)GKwikipedia
      GKwikipedia

Search more.