Colony stimulating factor 1 receptor

mammalian protein found in Homo sapiens

Wikidata entity: Q21100975



P682 biological process ... Q189101 (cell population proliferation) cell population proliferation
P682 biological process ... Q210861 (cell differentiation) cell differentiation
P682 biological process ... Q242736 (phosphorylation) phosphorylation
P682 biological process ... Q428253 (innate immune response) innate immune response
P682 biological process ... Q828130 (signal transduction) signal transduction
P682 biological process ... Q919283 (hemopoiesis) hemopoiesis
P682 biological process ... Q2034716 (axon guidance) axon guidance
P682 biological process ... Q3630494 (protein autophosphorylation) protein autophosphorylation
P682 biological process ... Q7251493 (protein phosphorylation) protein phosphorylation
P682 biological process ... Q14330986 (peptidyl-tyrosine phosphorylation) peptidyl-tyrosine phosphorylation
P682 biological process ... Q14331083 (positive regulation of protein tyrosine kinase activity) positive regulation of protein tyrosine kinase activity
P682 biological process ... Q14599399 (negative regulation of cell population proliferation) negative regulation of cell population proliferation
P682 biological process ... Q14599533 (negative regulation of apoptotic process) negative regulation of apoptotic process
P682 biological process ... Q14633891 (positive regulation of cell population proliferation) positive regulation of cell population proliferation
P682 biological process ... Q14645705 (multicellular organism development) multicellular organism development
P682 biological process ... Q14758919 (positive regulation of cell migration) positive regulation of cell migration
P682 biological process ... Q14758936 (positive regulation of MAPK cascade) positive regulation of MAPK cascade
P682 biological process ... Q14818111 (response to ischemia) response to ischemia
P682 biological process ... Q14819462 (regulation of cell shape) regulation of cell shape
P682 biological process ... Q14819846 (positive regulation of protein phosphorylation) positive regulation of protein phosphorylation
P682 biological process ... Q14819849 (inflammatory response) inflammatory response
P682 biological process ... Q14821388 (positive regulation of ERK1 and ERK2 cascade) positive regulation of ERK1 and ERK2 cascade
P682 biological process ... Q14860557 (osteoclast differentiation) osteoclast differentiation
P682 biological process ... Q14860562 (positive regulation of cell motility) positive regulation of cell motility
P682 biological process ... Q14862267 (positive regulation of protein serine/threonine kinase activity) positive regulation of protein serine/threonine kinase activity
P682 biological process ... Q14863107 (cytokine-mediated signaling pathway) cytokine-mediated signaling pathway
P682 biological process ... Q14863112 (cellular response to cytokine stimulus) cellular response to cytokine stimulus
P682 biological process ... Q14863362 (transmembrane receptor protein tyrosine kinase signaling pathway) transmembrane receptor protein tyrosine kinase signaling pathway
P682 biological process ... Q14863700 (phosphatidylinositol-mediated signaling) phosphatidylinositol-mediated signaling
P682 biological process ... Q14865045 (ruffle organization) ruffle organization
P682 biological process ... Q14873996 (regulation of actin cytoskeleton reorganization) regulation of actin cytoskeleton reorganization
P682 biological process ... Q14877408 (mammary gland duct morphogenesis) mammary gland duct morphogenesis
P682 biological process ... Q14903255 (hematopoietic progenitor cell differentiation) hematopoietic progenitor cell differentiation
P682 biological process ... Q14903301 (monocyte differentiation) monocyte differentiation
P682 biological process ... Q14903307 (macrophage differentiation) macrophage differentiation
P682 biological process ... Q14905137 (negative regulation of signal transduction) negative regulation of signal transduction
P682 biological process ... Q14906016 (regulation of bone resorption) regulation of bone resorption
P682 biological process ... Q14907233 (positive regulation of tyrosine phosphorylation of STAT protein) positive regulation of tyrosine phosphorylation of STAT protein
P682 biological process ... Q14912887 (cell-cell junction maintenance) cell-cell junction maintenance
P682 biological process ... Q14913260 (olfactory bulb development) olfactory bulb development
P682 biological process ... Q14916317 (immune system process) immune system process
P682 biological process ... Q15335151 (phosphatidylinositol metabolic process) phosphatidylinositol metabolic process
P682 biological process ... Q21100331 (positive regulation by host of viral process) positive regulation by host of viral process
P682 biological process ... Q21100593 (cellular response to macrophage colony-stimulating factor stimulus) cellular response to macrophage colony-stimulating factor stimulus
P682 biological process ... Q21100974 (macrophage colony-stimulating factor signaling pathway) macrophage colony-stimulating factor signaling pathway
P682 biological process ... Q21107257 (forebrain neuron differentiation) forebrain neuron differentiation
P682 biological process ... Q21172366 (microglial cell proliferation) microglial cell proliferation
P681 cell component ... Q79899 (cytoplasm) cytoplasm
P681 cell component ... Q189094 (cell surface) cell surface
P681 cell component ... Q29548 (plasma membrane) plasma membrane
P681 cell component ... Q14327652 (integral component of membrane) integral component of membrane
P681 cell component ... Q14349455 (membrane) membrane
P681 cell component ... Q14349519 (intracellular membrane-bounded organelle) intracellular membrane-bounded organelle
P681 cell component ... Q14817956 (nucleoplasm) nucleoplasm
P681 cell component ... Q14859540 (integral component of plasma membrane) integral component of plasma membrane
P681 cell component ... Q14877465 (receptor complex) receptor complex
P681 cell component ... Q21100973 (CSF1-CSF1R complex) CSF1-CSF1R complex
P591 EC enzyme number String 2.7.10.1 ???
P702 encoded by ... Q5148523 (CSF1R) CSF1R
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P527 has part(s) ... Q24719835 (tyrosine-protein kinase, catalytic domain) tyrosine-protein kinase, catalytic domain
P527 has part(s) ... Q24738472 (tyrosine-protein kinase, active site) tyrosine-protein kinase, active site
P527 has part(s) ... Q24740842 (serine-threonine/tyrosine-protein kinase, catalytic domain) serine-threonine/tyrosine-protein kinase, catalytic domain
P527 has part(s) ... Q24768234 (protein kinase domain) protein kinase domain
P527 has part(s) ... Q24769051 (protein kinase, ATP binding site) protein kinase, ATP binding site
P527 has part(s) ... Q24770541 (immunoglobulin domain) immunoglobulin domain
P527 has part(s) ... Q24771265 (tyrosine-protein kinase, receptor class III, conserved site) tyrosine-protein kinase, receptor class III, conserved site
P527 has part(s) ... Q24774513 (immunoglobulin subtype 2) immunoglobulin subtype 2
P527 has part(s) ... Q24783253 (immunoglobulin-like domain) immunoglobulin-like domain
P527 has part(s) ... Q24786036 (immunoglobulin subtype) immunoglobulin subtype
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q167149 (protein binding) protein binding
P680 molecular function ... Q420511 (receptor tyrosine kinase) receptor tyrosine kinase
P680 molecular function ... Q14762996 (protein homodimerization activity) protein homodimerization activity
P680 molecular function ... Q14817981 (ATP binding) ATP binding
P680 molecular function ... Q14820641 (protein kinase activity) protein kinase activity
P680 molecular function ... Q14840131 (transferase activity) transferase activity
P680 molecular function ... Q14860365 (nucleotide binding) nucleotide binding
P680 molecular function ... Q14863060 (protein phosphatase binding) protein phosphatase binding
P680 molecular function ... Q14863082 (kinase activity) kinase activity
P680 molecular function ... Q14863338 (protein tyrosine kinase activity) protein tyrosine kinase activity
P680 molecular function ... Q14863358 (transmembrane receptor protein tyrosine kinase activity) transmembrane receptor protein tyrosine kinase activity
P680 molecular function ... Q14864356 (transmembrane signaling receptor activity) transmembrane signaling receptor activity
P680 molecular function ... Q14874270 (cytokine binding) cytokine binding
P680 molecular function ... Q21100972 (macrophage colony-stimulating factor receptor activity) macrophage colony-stimulating factor receptor activity
P361 part of ... Q95352684 (Tyrosine-protein kinase, active site, protein family) Tyrosine-protein kinase, active site, protein family
P361 part of ... Q95354221 (Protein kinase, ATP binding site, protein family) Protein kinase, ATP binding site, protein family
P361 part of ... Q83130430 (Tyrosine-protein kinase, catalytic domain, protein family) Tyrosine-protein kinase, catalytic domain, protein family
P361 part of ... Q83137014 (Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family) Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
P361 part of ... Q83138186 (Protein kinase domain, protein family) Protein kinase domain, protein family
P361 part of ... Q83139936 (Immunoglobulin domain, protein family) Immunoglobulin domain, protein family
P361 part of ... Q83141582 (Immunoglobulin subtype 2, protein family) Immunoglobulin subtype 2, protein family
P361 part of ... Q83163490 (immunoglobulin-like domain, protein family) immunoglobulin-like domain, protein family
P361 part of ... Q83165367 (immunoglobulin subtype, protein family) immunoglobulin subtype, protein family
P361 part of ... Q95352117 (Tyrosine-protein kinase, receptor class III, conserved site, protein family) Tyrosine-protein kinase, receptor class III, conserved site, protein family
P361 part of ... Q24726164 (Protein kinase-like domain superfamily) Protein kinase-like domain superfamily
P361 part of ... Q24745090 (Macrophage colony-stimulating factor 1 receptor) Macrophage colony-stimulating factor 1 receptor
P361 part of ... Q24787648 (Immunoglobulin-like fold) Immunoglobulin-like fold
P361 part of ... Q41797304 (Immunoglobulin-like domain superfamily) Immunoglobulin-like domain superfamily
P129 physically interacts with ... Q5057052 (cediranib) cediranib
P129 physically interacts with ... Q5184160 (crenolanib) crenolanib
P129 physically interacts with ... Q6554172 (linifanib) linifanib
P129 physically interacts with ... Q7157043 (pazopanib) pazopanib
P129 physically interacts with ... Q25326691 (Emactuzumab) Emactuzumab
P129 physically interacts with ... Q27077188 (enmd-981693) enmd-981693

External Ids
P705Ensembl protein IDENSP00000427545
P705Ensembl protein IDENSP00000445282
P705Ensembl protein IDENSP00000421174
P705Ensembl protein IDENSP00000422212
P705Ensembl protein IDENSP00000286301
P638PDB structure ID4R7H
P638PDB structure ID2I0Y
P638PDB structure ID3DPK
P638PDB structure ID3KRL
P638PDB structure ID4HW7
P638PDB structure ID2I1M
P638PDB structure ID3BEA
P638PDB structure ID3LCD
P638PDB structure ID3LCO
P638PDB structure ID2I0V
P638PDB structure ID4R7I
P638PDB structure ID3KRJ
P638PDB structure ID4WRL
P638PDB structure ID4WRM
P638PDB structure ID2OGV
P638PDB structure ID4DKD
P638PDB structure ID4LIQ
P637RefSeq protein IDNP_001275634
P637RefSeq protein IDNP_001336665
P637RefSeq protein IDNP_001362249
P637RefSeq protein IDNP_001362250
P637RefSeq protein IDNP_005202
P352UniProt protein IDP07333

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