GATA binding protein 3

mammalian protein found in Homo sapiens

GATA binding protein 3 is …
instance of (P31):
proteinQ8054

External links are
P705Ensembl protein IDENSP00000341619
ENSP00000368632
ENSP00000493486
ENSP00000494284
P638PDB structure ID4HC7
4HC9
4HCA
P637RefSeq protein IDNP_001002295
NP_002042
XP_005252499
XP_005252500
P352UniProt protein IDP23771

P682biological processblood coagulationQ179217
innate immune responseQ428253
signal transductionQ828130
nervous system developmentQ1345738
axon guidanceQ2034716
kidney developmentQ2336077
tissue developmentQ2355306
mast cell differentiationQ14887724
neuron differentiationQ14897720
cochlea developmentQ14897879
cell fate determinationQ5058196
chromatin remodelingQ5113739
type IV hypersensitivityQ7860879
neuron migrationQ14330959
negative regulation of cell population proliferationQ14599399
response to estrogenQ14599729
uterus developmentQ14902305
regulation of nephron tubule epithelial cell differentiationQ14902792
regulation of epithelial cell differentiationQ14902816
ureteric bud formationQ14903051
positive regulation of transcription regulatory region DNA bindingQ14904612
pharyngeal system developmentQ14905139
homeostasis of number of cellsQ14905398
regulation of hematopoietic stem cell differentiationQ14905689
aortic valve morphogenesisQ14906410
thymic T cell selectionQ14907113
cellular response to interleukin-4Q14907264
cardiac right ventricle morphogenesisQ14908054
lens development in camera-type eyeQ14911569
parathyroid gland developmentQ14911571
negative regulation of endothelial cell apoptotic processQ14912175
ureter maturationQ14912383
pro-T cell differentiationQ14912393
positive regulation of ureteric bud formationQ14916285
immune system processQ14916317
mesenchymal to epithelial transitionQ15321815
in utero embryonic developmentQ14818001
response to gamma radiationQ14818040
T cell differentiation in thymusQ14818053
positive regulation of transcription, DNA-templatedQ14818066
positive regulation of transcription by RNA polymerase IIQ14818068
regulation of neuron apoptotic processQ14818122
heart developmentQ14819288
cell activationQ14819478
negative regulation of gene expressionQ14819859
response to ethanolQ14819884
post-embryonic developmentQ14820052
defense responseQ14820936
negative regulation of transcription by RNA polymerase IIQ14633878
regulation of transcription, DNA-templatedQ14633883
positive regulation of gene expressionQ14633893
negative regulation of transcription, DNA-templatedQ14633919
positive regulation of cell differentiationQ14758939
positive regulation of protein kinase B signalingQ14761970
transcription, DNA-templatedQ14763010
negative regulation of cell motilityQ21095304
cellular response to interferon-alphaQ21096372
positive regulation of interleukin-5 productionQ21097501
regulation of establishment of cell polarityQ21100656
nephric duct morphogenesisQ21101202
parathyroid hormone secretionQ21101519
regulation of CD4-positive, alpha-beta T cell differentiationQ21101520
regulation of histone H3-K27 methylationQ21101521
canonical Wnt signaling pathway involved in metanephric kidney developmentQ21101522
nephric duct formationQ21101523
negative regulation of cell proliferation involved in mesonephros developmentQ21101525
positive regulation of thyroid hormone generationQ21101526
regulation of cellular response to X-rayQ21101529
negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formationQ21101530
negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formationQ21101531
regulation of histone H3-K4 methylationQ21101533
ventricular septum developmentQ21101535
negative regulation of DNA demethylationQ21102211
positive regulation of histone H3-K14 acetylationQ21108307
positive regulation of T-helper 2 cell cytokine productionQ21116505
ureter morphogenesisQ21127255
lymphocyte migrationQ22269997
positive regulation of cytokine productionQ14851900
regulation of transcription by RNA polymerase IIQ14852032
erythrocyte differentiationQ14852033
mesonephros developmentQ14859568
male gonad developmentQ14859572
cell maturationQ14859575
positive regulation of endothelial cell migrationQ14859610
cell developmentQ14859963
thymus developmentQ14859964
renal system developmentQ14860014
embryonic organ developmentQ14860195
developmental growthQ14860196
anatomical structure formation involved in morphogenesisQ14860198
positive regulation of signal transductionQ14860471
negative regulation of inflammatory responseQ14861060
positive regulation of histone H3-K9 acetylationQ14862216
cytokine-mediated signaling pathwayQ14863107
cellular response to cytokine stimulusQ14863112
animal organ morphogenesisQ14863363
humoral immune responseQ14863386
ear developmentQ14863416
cell morphogenesisQ14863448
immune system developmentQ14863467
T cell differentiationQ14863504
T cell receptor signaling pathwayQ14863970
negative regulation of fat cell differentiationQ14864037
anatomical structure morphogenesisQ14864210
protein deubiquitinationQ14864234
negative regulation of interferon-gamma productionQ14864447
positive regulation of T cell differentiationQ14864518
transcription by RNA polymerase IIQ14864650
negative regulation of mammary gland epithelial cell proliferationQ14864733
response to virusQ14864931
negative regulation of interleukin-2 productionQ14865629
positive regulation of interleukin-4 productionQ14865633
positive regulation of interleukin-13 productionQ14865935
T-helper 2 cell differentiationQ14865939
embryonic hemopoiesisQ14866167
negative regulation of cell cycleQ14873927
cellular response to tumor necrosis factorQ14875882
TOR signalingQ14876079
digestive tract developmentQ14877292
phosphatidylinositol 3-kinase signalingQ14877475
sympathetic nervous system developmentQ14877500
inner ear morphogenesisQ14877676
otic vesicle developmentQ14877679
cellular response to BMP stimulusQ14877680
regulation of neuron projection developmentQ14878350
norepinephrine biosynthetic processQ14884579
P681cell componentnucleusQ40260
transcription regulator complexQ14818102
nucleoplasmQ14817956
P702encoded byGATA3Q18025464
P703found in taxonHomo sapiensQ15978631
P527has part(s)Zinc finger, GATA-typeQ24741806
P680molecular functionprotein bindingQ167149
HMG box domain bindingQ14888055
cis-regulatory region sequence-specific DNA bindingQ14888097
core promoter sequence-specific DNA bindingQ14902296
metal ion bindingQ13667380
DNA bindingQ14633858
transcription coregulator activityQ14908256
DNA-binding transcription activator activity, RNA polymerase II-specificQ14817973
chromatin bindingQ14817976
DNA-binding transcription factor activityQ14817979
transcription factor bindingQ14817982
sequence-specific DNA bindingQ14818107
zinc ion bindingQ14633865
DNA-binding transcription repressor activity, RNA polymerase II-specificQ21097436
transcription coactivator activityQ14860440
protein dimerization activityQ14861864
E-box bindingQ14864477
interleukin-2 receptor bindingQ14864499
DNA-binding transcription factor activity, RNA polymerase II-specificQ14864645
transcription cis-regulatory region bindingQ14864804
RNA polymerase II transcription regulatory region sequence-specific DNA bindingQ14864823
RNA polymerase II cis-regulatory region sequence-specific DNA bindingQ14885806
P361part ofTranscription factor GATA-3Q24727020
Zinc finger, NHR/GATA-typeQ24768526
Zinc finger, GATA-type, protein familyQ83137627

Reverse relations

has part(s) (P527)
Q55192552CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm]
Q55219951ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators
Q55192623ESR1:ESTG:PGR:P4:FOXA1:GATA3:TLE3:NRIP:EP300 [nucleoplasm]
Q50292655Expression of GATA3
Q55219909FOXA1 and GATA3 bind TFF genes
Q55219869FOXA1 and GATA3 bind to CCND1 promoter
Q50259634GATA proteins [nucleoplasm]
Q50258315GATA1,GATA2,GATA3 [nucleoplasm]
Q50268974GATA3,IL33 [nucleoplasm]
Q50258323GATA3-TAL1 core complex [nucleoplasm]
Q55194690TFF1 gene:FOXA1:GATA3 [nucleoplasm]
Q55194691TFF3 gene:FOXA1:GATA3 [nucleoplasm]

main subject (P921)
Q21092847A missense GATA3 mutation, Thr272Ile, causes the hypoparathyroidism, deafness, and renal dysplasia syndrome
Q24312921Abundant expression of Kallikrein 1 gene in human keratinocytes was mediated by GATA3
Q24315620Activation of the Interleukin-5 Promoter by cAMP in Murine EL-4 Cells Requires the GATA-3 and CLE0 Elements
Q24317106Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment
Q22008809Combining SSH and cDNA microarrays for rapid identification of differentially expressed genes
Q24324196Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells
Q24322775Cutting edge: Type I IFN reverses human Th2 commitment and stability by suppressing GATA3
Q24295089GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis
Q22254758GATA3 haplo-insufficiency causes human HDR syndrome
Q24315703GATA3 inhibits breast cancer growth and pulmonary breast cancer metastasis
Q24301339GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition
Q24313845GATA3 is a master regulator of the transcriptional response to low-dose ionizing radiation in human keratinocytes
Q24305581GATA3 siRNA inhibits the binding of NFAT1 to interleukin-13 promoter in human T cells
Q24684456Gata-3 and mammary cell fate
Q24315737HDR syndrome: a novel "de novo" mutation in GATA3 gene
Q24316239Interaction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signaling
Q24336392Lymphoid enhancer factor interacts with GATA-3 and controls its function in T helper type 2 cells
Q36546530MiR-573 inhibits prostate cancer metastasis by regulating epithelial-mesenchymal transition
Q24300295NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia
Q24336673T-bet, GATA-3, and Foxp3 expression and Th1/Th2 cytokine production in the clinical outcome of human infection with Leishmania (Viannia) species
Q24324104The human enhancer-binding protein Gata3 binds to several T-cell receptor regulatory elements
Q24321949The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes
Q24313643c-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell development

Q50373623PolyUb-GATA3 [nucleoplasm]subclass ofP279
Q18025464GATA3encodesP688

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