E2F transcription factor 4

mammalian protein found in Homo sapiens

E2F transcription factor 4 is …
instance of (P31):
proteinQ8054

External links are
P705Ensembl protein IDENSP00000368686
ENSP00000454477
ENSP00000457239
ENSP00000458082
ENSP00000458706
P486MeSH descriptor IDD050704
P672MeSH tree codeD12.776.930.211.812
P638PDB structure ID1CF7
P637RefSeq protein IDNP_001941
P2892UMLS CUIC0291135
P352UniProt protein IDQ16254

P682biological processcell cycleQ188941
negative regulation of transcription by RNA polymerase IIQ14633878
regulation of transcription, DNA-templatedQ14633883
mitotic cell cycleQ14763008
transcription, DNA-templatedQ14763010
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestQ14818020
positive regulation of transcription by RNA polymerase IIQ14818068
regulation of cell population proliferationQ14818120
regulation of cell cycleQ14818129
blood circulationQ14852003
animal organ morphogenesisQ14863363
transcription by RNA polymerase IIQ14864650
epithelial cell developmentQ14874284
cell projection organizationQ14876090
regulation of transcription involved in G1/S transition of mitotic cell cycleQ14902236
cell volume homeostasisQ14902521
cilium assemblyQ14916348
multi-ciliated epithelial cell differentiationQ21097395
motile cilium assemblyQ21105422
centriole assemblyQ21105841
regulation of cell sizeQ21107547
P681cell componentnucleusQ40260
nucleoplasmQ14817956
transcription regulator complexQ14818102
RNA polymerase II transcription regulator complexQ21095257
P702encoded byE2F4Q17915120
P703found in taxonHomo sapiensQ15978631
P527has part(s)E2F/DP family, winged-helix DNA-binding domainQ24773372
E2F transcription factor, CC-MB domainQ24777948
P680molecular functionprotein bindingQ167149
DNA bindingQ14633858
DNA-binding transcription activator activity, RNA polymerase II-specificQ14817973
DNA-binding transcription factor activityQ14817979
transcription factor bindingQ14817982
sequence-specific DNA bindingQ14818107
protein domain specific bindingQ14860854
protein dimerization activityQ14861864
DNA-binding transcription factor activity, RNA polymerase II-specificQ14864645
RNA polymerase II cis-regulatory region sequence-specific DNA bindingQ14885806
DNA-binding transcription repressor activity, RNA polymerase II-specificQ21097436
promoter-specific chromatin bindingQ22312996
P361part ofTranscription factor E2F4Q24772661
Winged helix-like DNA-binding domain superfamilyQ41797502
winged helix DNA-binding domain superfamilyQ41797505
E2F-DP heterodimerization regionQ41798321
E2F/DP family, winged-helix DNA-binding domain, protein familyQ83141032
E2F transcription factor, CC-MB domain, protein familyQ83146275

Reverse relations

has part(s) (P527)
Q127384642DREAM transcriptional repressor complex, RBL1 variant
Q127383321DREAM transcriptional repressor complex, RBL2 variant
Q50250742E2F4,E2F5 [nucleoplasm]
Q127383447E2F4-DP1 transcriptional regulator complex
Q50258067E2F4:(TFDP1,TFDP2):(RBL1,RBL2) [nucleoplasm]
Q50250818E2F4:TFDP1,TFDP2 [nucleoplasm]
Q50250761RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]

main subject (P921)
Q24291353E2F transcriptional activation requires TRRAP and GCN5 cofactors
Q24309023Human TFDP3, a novel DP protein, inhibits DNA binding and transactivation by E2F
Q22010391In vivo structure of two divergent promoters at the human PCNA locus. Synthesis of antisense RNA and S phase-dependent binding of E2F complexes in intron 1
Q28117082MiR-15 and miR-16 are direct transcriptional targets of E2F1 that limit E2F-induced proliferation by targeting cyclin E
Q28118300Post-transcriptional gene expression control by NANOS is up-regulated and functionally important in pRb-deficient cells
Q24299116Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release

Q17915120E2F4encodesP688

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