Proteasome 26S subunit, non-ATPase 14

mammalian protein found in Homo sapiens

Wikidata entity: Q21108543



P682 biological process ... Q33123 (proteolysis) proteolysis
P682 biological process ... Q210538 (DNA repair) DNA repair
P682 biological process ... Q898362 (post-translational protein modification) post-translational protein modification
P682 biological process ... Q14633881 (antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent) antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
P682 biological process ... Q14758900 (MAPK cascade) MAPK cascade
P682 biological process ... Q14758906 (regulation of cellular amino acid metabolic process) regulation of cellular amino acid metabolic process
P682 biological process ... Q14818018 (cellular response to DNA damage stimulus) cellular response to DNA damage stimulus
P682 biological process ... Q14819884 (response to ethanol) response to ethanol
P682 biological process ... Q14820680 (transmembrane transport) transmembrane transport
P682 biological process ... Q14852022 (regulation of transcription from RNA polymerase II promoter in response to hypoxia) regulation of transcription from RNA polymerase II promoter in response to hypoxia
P682 biological process ... Q14860027 (negative regulation of canonical Wnt signaling pathway) negative regulation of canonical Wnt signaling pathway
P682 biological process ... Q14860442 (double-strand break repair via homologous recombination) double-strand break repair via homologous recombination
P682 biological process ... Q14860483 (positive regulation of canonical Wnt signaling pathway) positive regulation of canonical Wnt signaling pathway
P682 biological process ... Q14863376 (protein polyubiquitination) protein polyubiquitination
P682 biological process ... Q14863970 (T cell receptor signaling pathway) T cell receptor signaling pathway
P682 biological process ... Q14864211 (tumor necrosis factor-mediated signaling pathway) tumor necrosis factor-mediated signaling pathway
P682 biological process ... Q14864233 (ubiquitin-dependent protein catabolic process) ubiquitin-dependent protein catabolic process
P682 biological process ... Q14864234 (protein deubiquitination) protein deubiquitination
P682 biological process ... Q14864810 (interleukin-1-mediated signaling pathway) interleukin-1-mediated signaling pathway
P682 biological process ... Q14874299 (Fc-epsilon receptor signaling pathway) Fc-epsilon receptor signaling pathway
P682 biological process ... Q14897651 (Wnt signaling pathway, planar cell polarity pathway) Wnt signaling pathway, planar cell polarity pathway
P682 biological process ... Q14905689 (regulation of hematopoietic stem cell differentiation) regulation of hematopoietic stem cell differentiation
P682 biological process ... Q14905702 (anaphase-promoting complex-dependent catabolic process) anaphase-promoting complex-dependent catabolic process
P682 biological process ... Q14907360 (regulation of mRNA stability) regulation of mRNA stability
P682 biological process ... Q14911651 (neutrophil degranulation) neutrophil degranulation
P682 biological process ... Q14911701 (double-strand break repair via nonhomologous end joining) double-strand break repair via nonhomologous end joining
P682 biological process ... Q15323465 (SCF-dependent proteasomal ubiquitin-dependent protein catabolic process) SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
P682 biological process ... Q15323482 (proteasome-mediated ubiquitin-dependent protein catabolic process) proteasome-mediated ubiquitin-dependent protein catabolic process
P682 biological process ... Q15329749 (regulation of proteasomal protein catabolic process) regulation of proteasomal protein catabolic process
P682 biological process ... Q21095148 (regulation of mitotic cell cycle phase transition) regulation of mitotic cell cycle phase transition
P682 biological process ... Q21095173 (stimulatory C-type lectin receptor signaling pathway) stimulatory C-type lectin receptor signaling pathway
P682 biological process ... Q21100454 (protein K63-linked deubiquitination) protein K63-linked deubiquitination
P682 biological process ... Q21100852 (NIK/NF-kappaB signaling) NIK/NF-kappaB signaling
P682 biological process ... Q21103083 (negative regulation of G2/M transition of mitotic cell cycle) negative regulation of G2/M transition of mitotic cell cycle
P682 biological process ... Q21108541 (positive regulation of endopeptidase activity) positive regulation of endopeptidase activity
P681 cell component ... Q40260 (nucleus) nucleus
P681 cell component ... Q220599 (cytosol) cytosol
P681 cell component ... Q903634 (extracellular exosome) extracellular exosome
P681 cell component ... Q14645596 (extracellular region) extracellular region
P681 cell component ... Q14758893 (secretory granule lumen) secretory granule lumen
P681 cell component ... Q14817956 (nucleoplasm) nucleoplasm
P681 cell component ... Q14878333 (proteasome complex) proteasome complex
P681 cell component ... Q14914036 (cytosolic proteasome complex) cytosolic proteasome complex
P681 cell component ... Q21105834 (proteasome accessory complex) proteasome accessory complex
P681 cell component ... Q21108540 (proteasome regulatory particle, lid subcomplex) proteasome regulatory particle, lid subcomplex
P681 cell component ... Q22328083 (ficolin-1-rich granule lumen) ficolin-1-rich granule lumen
P702 encoded by ... Q18035128 (PSMD14) PSMD14
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P527 has part(s) ... Q24768584 (JAB1/MPN/MOV34 metalloenzyme domain) JAB1/MPN/MOV34 metalloenzyme domain
P527 has part(s) ... Q24781723 (Rpn11/EIF3F, C-terminal) Rpn11/EIF3F, C-terminal
P527 has part(s) ... Q43921561 (MPN domain) MPN domain
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q167149 (protein binding) protein binding
P680 molecular function ... Q13667380 (metal ion binding) metal ion binding
P680 molecular function ... Q14353168 (hydrolase activity) hydrolase activity
P680 molecular function ... Q14645703 (peptidase activity) peptidase activity
P680 molecular function ... Q14863977 (metallopeptidase activity) metallopeptidase activity
P680 molecular function ... Q21097542 (thiol-dependent deubiquitinase) thiol-dependent deubiquitinase
P680 molecular function ... Q21101364 (proteasome binding) proteasome binding
P680 molecular function ... Q21108542 (endopeptidase activator activity) endopeptidase activator activity
P680 molecular function ... Q21117461 (Lys63-specific deubiquitinase activity) Lys63-specific deubiquitinase activity
P361 part of ... Q32855499 (26S Proteasome non-ATPase regulatory subunit 14) 26S Proteasome non-ATPase regulatory subunit 14
P361 part of ... Q83138627 (JAB1/MPN/MOV34 metalloenzyme domain family) JAB1/MPN/MOV34 metalloenzyme domain family
P361 part of ... Q83162581 (Rpn11/EIF3F, C-terminal domain, protein family) Rpn11/EIF3F, C-terminal domain, protein family
P361 part of ... Q83171089 (MPN domain, protein family) MPN domain, protein family
P129 physically interacts with ... Q15366934 (carfilzomib) carfilzomib
P129 physically interacts with ... Q20948663 (ixazomib) ixazomib
P129 physically interacts with ... Q25104721 (Oprozomib) Oprozomib

External Ids
P705Ensembl protein IDENSP00000399311
P705Ensembl protein IDENSP00000386541
P637RefSeq protein IDNP_005796
P352UniProt protein IDO00487

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