NCK adaptor protein 1

mammalian protein found in Homo sapiens

Wikidata entity: Q21113662



P682 biological process ... Q189092 (cell migration) cell migration
P682 biological process ... Q14330979 (positive regulation of neuron projection development) positive regulation of neuron projection development
P682 biological process ... Q14818068 (positive regulation of transcription by RNA polymerase II) positive regulation of transcription by RNA polymerase II
P682 biological process ... Q14819896 (negative regulation of cell death) negative regulation of cell death
P682 biological process ... Q14860555 (actin filament organization) actin filament organization
P682 biological process ... Q14860833 (regulation of cell migration) regulation of cell migration
P682 biological process ... Q14863108 (positive regulation of actin filament polymerization) positive regulation of actin filament polymerization
P682 biological process ... Q14863717 (regulation of translation) regulation of translation
P682 biological process ... Q14863968 (Fc-gamma receptor signaling pathway involved in phagocytosis) Fc-gamma receptor signaling pathway involved in phagocytosis
P682 biological process ... Q14863969 (T cell activation) T cell activation
P682 biological process ... Q14863970 (T cell receptor signaling pathway) T cell receptor signaling pathway
P682 biological process ... Q14864277 (negative regulation of peptidyl-serine phosphorylation) negative regulation of peptidyl-serine phosphorylation
P682 biological process ... Q14864517 (positive regulation of T cell proliferation) positive regulation of T cell proliferation
P682 biological process ... Q14865215 (negative regulation of protein kinase activity) negative regulation of protein kinase activity
P682 biological process ... Q14873293 (lamellipodium assembly) lamellipodium assembly
P682 biological process ... Q14885636 (vascular endothelial growth factor receptor signaling pathway) vascular endothelial growth factor receptor signaling pathway
P682 biological process ... Q14905487 (ephrin receptor signaling pathway) ephrin receptor signaling pathway
P682 biological process ... Q14906583 (signal complex assembly) signal complex assembly
P682 biological process ... Q14907898 (response to other organism) response to other organism
P682 biological process ... Q14912640 (negative regulation of insulin receptor signaling pathway) negative regulation of insulin receptor signaling pathway
P682 biological process ... Q21095094 (substrate-dependent cell migration, cell extension) substrate-dependent cell migration, cell extension
P682 biological process ... Q21100269 (positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway) positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
P682 biological process ... Q21104707 (negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress) negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
P682 biological process ... Q21104708 (negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
P682 biological process ... Q21104709 (positive regulation of translation in response to endoplasmic reticulum stress) positive regulation of translation in response to endoplasmic reticulum stress
P682 biological process ... Q21104710 (negative regulation of PERK-mediated unfolded protein response) negative regulation of PERK-mediated unfolded protein response
P682 biological process ... Q21112033 (peptidyl-serine dephosphorylation) peptidyl-serine dephosphorylation
P682 biological process ... Q21113660 (positive regulation of cap-dependent translational initiation) positive regulation of cap-dependent translational initiation
P682 biological process ... Q21113661 (positive regulation of cap-independent translational initiation) positive regulation of cap-independent translational initiation
P681 cell component ... Q79899 (cytoplasm) cytoplasm
P681 cell component ... Q29548 (plasma membrane) plasma membrane
P681 cell component ... Q40260 (nucleus) nucleus
P681 cell component ... Q42244 (ribosome) ribosome
P681 cell component ... Q79927 (endoplasmic reticulum) endoplasmic reticulum
P681 cell component ... Q220599 (cytosol) cytosol
P681 cell component ... Q14863961 (vesicle membrane) vesicle membrane
P681 cell component ... Q14873267 (cell-cell junction) cell-cell junction
P681 cell component ... Q21109480 (protein phosphatase type 1 complex) protein phosphatase type 1 complex
P702 encoded by ... Q18029884 (NCK1) NCK1
P2888 exact match Url UniProt ???
P2888 exact match Url UniProt ???
P2888 exact match Url None ???
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P527 has part(s) ... Q32855754 (Nck1, SH3 domain 1) Nck1, SH3 domain 1
P527 has part(s) ... Q32855756 (Nck1, SH3 domain 2) Nck1, SH3 domain 2
P527 has part(s) ... Q32855757 (Nck1, SH3 domain 3) Nck1, SH3 domain 3
P527 has part(s) ... Q41797033 (Nck1, SH2 domain) Nck1, SH2 domain
P527 has part(s) ... Q24771787 (SH3 domain) SH3 domain
P527 has part(s) ... Q24780316 (SH2 domain) SH2 domain
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q167149 (protein binding) protein binding
P680 molecular function ... Q14817985 (receptor tyrosine kinase binding) receptor tyrosine kinase binding
P680 molecular function ... Q14819233 (signaling receptor binding) signaling receptor binding
P680 molecular function ... Q14860854 (protein domain specific binding) protein domain specific binding
P680 molecular function ... Q14873292 (cadherin binding) cadherin binding
P680 molecular function ... Q14897681 (ephrin receptor binding) ephrin receptor binding
P680 molecular function ... Q14902455 (protein kinase inhibitor activity) protein kinase inhibitor activity
P680 molecular function ... Q14906108 (protein-macromolecule adaptor activity) protein-macromolecule adaptor activity
P680 molecular function ... Q14906594 (signaling receptor complex adaptor activity) signaling receptor complex adaptor activity
P680 molecular function ... Q14914377 (molecular adaptor activity) molecular adaptor activity
P680 molecular function ... Q21097224 (cytoskeletal anchor activity) cytoskeletal anchor activity
P680 molecular function ... Q21113659 (eukaryotic initiation factor eIF2 binding) eukaryotic initiation factor eIF2 binding
P361 part of ... Q41797170 (SH3-like domain superfamily) SH3-like domain superfamily
P361 part of ... Q41797956 (SH2 domain superfamily) SH2 domain superfamily
P361 part of ... Q83140574 (SH3 domain, protein family) SH3 domain, protein family
P361 part of ... Q83164644 (SH2 domain, protein family) SH2 domain, protein family
P361 part of ... Q83170740 (Nck1, SH2 domain, protein family) Nck1, SH2 domain, protein family
P361 part of ... Q83171721 (Nck1, SH3 domain 2, protein family) Nck1, SH3 domain 2, protein family
P361 part of ... Q83171774 (Nck1, SH3 domain 3, protein family) Nck1, SH3 domain 3, protein family
P361 part of ... Q83171837 (Nck1, SH3 domain 1, protein family) Nck1, SH3 domain 1, protein family
P361 part of ... Q24778403 (Cytoplasmic protein NCK) Cytoplasmic protein NCK

External Ids
P705Ensembl protein IDENSP00000419544
P705Ensembl protein IDENSP00000418060
P705Ensembl protein IDENSP00000417273
P705Ensembl protein IDENSP00000419302
P705Ensembl protein IDENSP00000288986
P705Ensembl protein IDENSP00000419631
P705Ensembl protein IDENSP00000418513
P705Ensembl protein IDENSP00000417729
P705Ensembl protein IDENSP00000419677
P638PDB structure ID2CI8
P638PDB structure ID2CI9
P638PDB structure ID2JS0
P638PDB structure ID2JS2
P638PDB structure ID2JW4
P637RefSeq protein IDNP_001177725
P637RefSeq protein IDNP_001278928
P637RefSeq protein IDNP_006144
P637RefSeq protein IDXP_024309306
P352UniProt protein IDP16333

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