Proteasome 20S subunit beta 8

mammalian protein found in Homo sapiens

Wikidata entity: Q21119744



P682 biological process ... Q33123 (proteolysis) proteolysis
P682 biological process ... Q210861 (cell differentiation) cell differentiation
P682 biological process ... Q14820680 (transmembrane transport) transmembrane transport
P682 biological process ... Q14852022 (regulation of transcription from RNA polymerase II promoter in response to hypoxia) regulation of transcription from RNA polymerase II promoter in response to hypoxia
P682 biological process ... Q14860027 (negative regulation of canonical Wnt signaling pathway) negative regulation of canonical Wnt signaling pathway
P682 biological process ... Q14860483 (positive regulation of canonical Wnt signaling pathway) positive regulation of canonical Wnt signaling pathway
P682 biological process ... Q14863376 (protein polyubiquitination) protein polyubiquitination
P682 biological process ... Q14863970 (T cell receptor signaling pathway) T cell receptor signaling pathway
P682 biological process ... Q14864067 (fat cell differentiation) fat cell differentiation
P682 biological process ... Q14864211 (tumor necrosis factor-mediated signaling pathway) tumor necrosis factor-mediated signaling pathway
P682 biological process ... Q14864234 (protein deubiquitination) protein deubiquitination
P682 biological process ... Q14864809 (type I interferon signaling pathway) type I interferon signaling pathway
P682 biological process ... Q898362 (post-translational protein modification) post-translational protein modification
P682 biological process ... Q14633881 (antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent) antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
P682 biological process ... Q14758900 (MAPK cascade) MAPK cascade
P682 biological process ... Q14758906 (regulation of cellular amino acid metabolic process) regulation of cellular amino acid metabolic process
P682 biological process ... Q21095148 (regulation of mitotic cell cycle phase transition) regulation of mitotic cell cycle phase transition
P682 biological process ... Q21095173 (stimulatory C-type lectin receptor signaling pathway) stimulatory C-type lectin receptor signaling pathway
P682 biological process ... Q21100852 (NIK/NF-kappaB signaling) NIK/NF-kappaB signaling
P682 biological process ... Q14864810 (interleukin-1-mediated signaling pathway) interleukin-1-mediated signaling pathway
P682 biological process ... Q14865169 (viral process) viral process
P682 biological process ... Q14874299 (Fc-epsilon receptor signaling pathway) Fc-epsilon receptor signaling pathway
P682 biological process ... Q14876119 (antigen processing and presentation) antigen processing and presentation
P682 biological process ... Q14897651 (Wnt signaling pathway, planar cell polarity pathway) Wnt signaling pathway, planar cell polarity pathway
P682 biological process ... Q14905468 (proteasomal protein catabolic process) proteasomal protein catabolic process
P682 biological process ... Q14905689 (regulation of hematopoietic stem cell differentiation) regulation of hematopoietic stem cell differentiation
P682 biological process ... Q14905702 (anaphase-promoting complex-dependent catabolic process) anaphase-promoting complex-dependent catabolic process
P682 biological process ... Q14907360 (regulation of mRNA stability) regulation of mRNA stability
P682 biological process ... Q14911964 (proteolysis involved in cellular protein catabolic process) proteolysis involved in cellular protein catabolic process
P682 biological process ... Q14916317 (immune system process) immune system process
P682 biological process ... Q14916426 (regulation of endopeptidase activity) regulation of endopeptidase activity
P682 biological process ... Q15323465 (SCF-dependent proteasomal ubiquitin-dependent protein catabolic process) SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
P682 biological process ... Q15323482 (proteasome-mediated ubiquitin-dependent protein catabolic process) proteasome-mediated ubiquitin-dependent protein catabolic process
P682 biological process ... Q21103083 (negative regulation of G2/M transition of mitotic cell cycle) negative regulation of G2/M transition of mitotic cell cycle
P682 biological process ... Q21104750 (proteasomal ubiquitin-independent protein catabolic process) proteasomal ubiquitin-independent protein catabolic process
P681 cell component ... Q79899 (cytoplasm) cytoplasm
P681 cell component ... Q40260 (nucleus) nucleus
P681 cell component ... Q220599 (cytosol) cytosol
P681 cell component ... Q14817956 (nucleoplasm) nucleoplasm
P681 cell component ... Q903634 (extracellular exosome) extracellular exosome
P681 cell component ... Q21101365 (proteasome core complex) proteasome core complex
P681 cell component ... Q14878333 (proteasome complex) proteasome complex
P681 cell component ... Q21111804 (spermatoproteasome complex) spermatoproteasome complex
P681 cell component ... Q22328793 (proteasome core complex, beta-subunit complex) proteasome core complex, beta-subunit complex
P702 encoded by ... Q18030864 (PSMB8) PSMB8
P2888 exact match Url UniProt ???
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P527 has part(s) ... Q24769832 (Proteasome beta-type subunit, conserved site) Proteasome beta-type subunit, conserved site
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q167149 (protein binding) protein binding
P680 molecular function ... Q14861555 (endopeptidase activity) endopeptidase activity
P680 molecular function ... Q14353168 (hydrolase activity) hydrolase activity
P680 molecular function ... Q14645703 (peptidase activity) peptidase activity
P680 molecular function ... Q21104748 (threonine-type endopeptidase activity) threonine-type endopeptidase activity
P361 part of ... Q24775249 (Nucleophile aminohydrolases, N-terminal) Nucleophile aminohydrolases, N-terminal
P361 part of ... Q32855887 (Proteasome subunit beta type 8) Proteasome subunit beta type 8
P361 part of ... Q95353302 (Proteasome beta-type subunit, conserved site, protein family) Proteasome beta-type subunit, conserved site, protein family
P129 physically interacts with ... Q20948663 (ixazomib) ixazomib
P129 physically interacts with ... Q15366934 (carfilzomib) carfilzomib
P129 physically interacts with ... Q25104721 (Oprozomib) Oprozomib

External Ids
P705Ensembl protein IDENSP00000407539
P705Ensembl protein IDENSP00000382538
P705Ensembl protein IDENSP00000406797
P705Ensembl protein IDENSP00000372723
P705Ensembl protein IDENSP00000394155
P705Ensembl protein IDENSP00000414770
P705Ensembl protein IDENSP00000364015
P705Ensembl protein IDENSP00000397057
P705Ensembl protein IDENSP00000406878
P705Ensembl protein IDENSP00000406913
P705Ensembl protein IDENSP00000412618
P705Ensembl protein IDENSP00000404615
P705Ensembl protein IDENSP00000408825
P705Ensembl protein IDENSP00000394090
P705Ensembl protein IDENSP00000402406
P705Ensembl protein IDENSP00000392693
P705Ensembl protein IDENSP00000404585
P705Ensembl protein IDENSP00000401868
P705Ensembl protein IDENSP00000378748
P705Ensembl protein IDENSP00000410205
P705Ensembl protein IDENSP00000396430
P705Ensembl protein IDENSP00000364016
P705Ensembl protein IDENSP00000372725
P705Ensembl protein IDENSP00000414731
P637RefSeq protein IDNP_004150
P637RefSeq protein IDNP_683720
P352UniProt protein IDP28062

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