Phyla- and Subtype-Selectivity of CgNa, a Na Channel Toxin from the Venom of the Giant Caribbean Sea Anemone Condylactis Gigantea

scientific article published in 2010

Phyla- and Subtype-Selectivity of CgNa, a Na Channel Toxin from the Venom of the Giant Caribbean Sea Anemone Condylactis Gigantea is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FPHAR.2010.00133
P932PMC publication ID3153007
P698PubMed publication ID21833172
P5875ResearchGate publication ID51563342

P50authorJan TytgatQ13735914
P2093author name stringBert Billen
Sarah Debaveye
Anoland Garateix
Lászlo Béress
P2860cites workSodium channels in normal and pathological painQ37724336
Sea anemone toxin and scorpion toxin share a common receptor site associated with the action potential sodium ionophoreQ39213623
A Specific Interaction between the Cardiac Sodium Channel and Site-3 Toxin Anthopleurin BQ41067774
Sodium channel mutations in paramyotonia congenita uncouple inactivation from activationQ41491359
Molecular analysis of the sea anemone toxin Av3 reveals selectivity to insects and demonstrates the heterogeneity of receptor site-3 on voltage-gated Na+ channelsQ42414897
Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs.Q42604432
Molecular determinant of Na(v)1.8 sodium channel resistance to the venom from the scorpion Leiurus quinquestriatus hebraeusQ44166501
Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory painQ44805364
Intron retention as a posttranscriptional regulatory mechanism of neurotoxin expression at early life stages of the starlet anemone Nematostella vectensisQ45800623
Molecular analysis of the para locus, a sodium channel gene in DrosophilaQ48287063
Effects of ApC, a sea anemone toxin, on sodium currents of mammalian neuronsQ48445874
Spinal sensory neurons express multiple sodium channel alpha-subunit mRNAsQ48826387
The sea anemone toxins BgII and BgIII prolong the inactivation time course of the tetrodotoxin-sensitive sodium current in rat dorsal root ganglion neurons.Q49012140
Potent modulation of the voltage-gated sodium channel Nav1.7 by OD1, a toxin from the scorpion Odonthobuthus doriae.Q50650043
Differential properties of tetrodotoxin-sensitive and tetrodotoxin- resistant sodium channels in rat dorsal root ganglion neuronsQ51690509
Neurotoxins as allosteric modifiers of voltage-sensitive sodium channelsQ52703952
Structural parts involved in activation and inactivation of the sodium channelQ59072056
CgNa, a type I toxin from the giant Caribbean sea anemone Condylactis gigantea shows structural similarities to both type I and II toxins, as well as distinctive structural and functional properties 1Q27644801
From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channelsQ28143653
Sea anemone toxins affecting voltage-gated sodium channels--molecular and evolutionary featuresQ33595191
Diversity of mammalian voltage-gated sodium channels.Q33691479
The Na channel voltage sensor associated with inactivation is localized to the external charged residues of domain IV, S4.Q33869265
The sea anemone Bunodosoma granulifera contains surprisingly efficacious and potent insect-selective toxins.Q34161908
Sodium channels and gating currentsQ34252607
Binding specificity of sea anemone toxins to Nav 1.1-1.6 sodium channels: unexpected contributions from differences in the IV/S3-S4 outer loop.Q34323654
Localization of the receptor site for alpha-scorpion toxins by antibody mapping: implications for sodium channel topologyQ34327263
Molecular determinants of high affinity binding of alpha-scorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na+ channel alpha subunitQ34384573
A new toxin from the sea anemone Condylactis gigantea with effect on sodium channel inactivation.Q34543540
The poison Dart frog's batrachotoxin modulates Nav1.8.Q34552425
Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channelsQ34708118
RNA editing generates tissue-specific sodium channels with distinct gating propertiesQ34731490
Revisiting cangitoxin, a sea anemone peptide: purification and characterization of cangitoxins II and III from the venom of Bunodosoma cangicumQ34761918
Actions of sea anemone type 1 neurotoxins on voltage-gated sodium channel isoforms.Q34977765
Inherited neuronal ion channelopathies: new windows on complex neurological diseasesQ35226085
Structure and function of delta-atracotoxins: lethal neurotoxins targeting the voltage-gated sodium channel.Q35739174
NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomyQ36229128
Sodium channel inactivation: molecular determinants and modulationQ36267779
From molecule to maladyQ36428969
A unique role for the S4 segment of domain 4 in the inactivation of sodium channelsQ36435804
Sodium channel activation gating is affected by substitutions of voltage sensor positive charges in all four domainsQ36435921
Sodium channel inactivation is altered by substitution of voltage sensor positive chargesQ36435941
Deconstructing voltage sensor function and pharmacology in sodium channelsQ36983062
Pathophysiology and pharmacology of the cardiac "late sodium current.".Q37228932
Peptide toxins that selectively target insect Na(V) and Ca(V) channelsQ37292215
A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivationQ37301303
Synthesis, solution structure, and phylum selectivity of a spider delta-toxin that slows inactivation of specific voltage-gated sodium channel subtypesQ37433422
Voltage-sensor mutations in channelopathies of skeletal muscleQ37692699
P407language of work or nameEnglishQ1860
P921main subjectCaribbean SeaQ1247
CaribbeanQ664609
Condylactis giganteaQ1729340
venomQ3386847
P304page(s)133
P577publication date2010-01-01
P1433published inFrontiers in PharmacologyQ2681208
P1476titlePhyla- and Subtype-Selectivity of CgNa, a Na Channel Toxin from the Venom of the Giant Caribbean Sea Anemone Condylactis Gigantea
P478volume1

Reverse relations

cites work (P2860)
Q41849096Functional coupling between sodium-activated potassium channels and voltage-dependent persistent sodium currents in cricket Kenyon cells
Q52881163Hemolytic, anticancer and antigiardial activity of Palythoa caribaeorum venom.
Q92637688New Insights into the Type II Toxins from the Sea Anemone Heteractis crispa
Q46082873Serrumab: a novel human single chain-fragment antibody with multiple scorpion toxin-neutralizing capacities

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