Prostaglandin E synthase 2

mammalian protein found in Homo sapiens

Prostaglandin E synthase 2 is …
instance of (P31):
proteinQ8054

External links are
P591EC enzyme number5.3.99.3
P705Ensembl protein IDENSP00000277462
ENSP00000345341
ENSP00000411378
ENSP00000482913
P637RefSeq protein IDNP_001243264
NP_079348
NP_945176
XP_005252296
XP_011517352
XP_011517353
XP_024303456
P352UniProt protein IDQ9H7Z7

P682biological processsecretionQ84230
electron transport chainQ211016
lipid metabolismQ2792936
positive regulation of transcription, DNA-templatedQ14818066
fatty acid biosynthetic processQ14860449
fatty acid metabolic processQ14860867
cell redox homeostasisQ14864622
cyclooxygenase pathwayQ14881692
prostaglandin biosynthetic processQ14881696
prostaglandin metabolic processQ14881697
neutrophil degranulationQ14911651
P681cell componentmitochondrionQ39572
nucleusQ40260
cytoplasmQ79899
Golgi apparatusQ83181
integral component of membraneQ14327652
perinuclear region of cytoplasmQ14330632
membraneQ14349455
Golgi membraneQ14598778
cytosolQ220599
extracellular regionQ14645596
azurophil granule lumenQ21101057
P702encoded byPTGES2Q18046593
P703found in taxonHomo sapiensQ15978631
P527has part(s)glutathione S-transferase, C-terminal-likeQ24770496
Glutaredoxin domainQ24779077
Glutathione S-transferase, N-terminalQ24787597
Prostaglandin E synthase 2, C-terminalQ28544360
P680molecular functionprotein bindingQ167149
electron transfer activityQ14358476
heme bindingQ14358516
DNA bindingQ14633858
lyase activityQ14859873
protein-disulfide reductase activityQ14864614
isomerase activityQ14865768
glutathione bindingQ14878283
prostaglandin-E synthase activityQ21130569
P361part ofProstaglandin E synthase 2Q28544359
Thioredoxin-like superfamilyQ41797370
Glutathione S-transferase, C-terminal domain superfamilyQ41797403
Glutaredoxin familyQ81984039
Glutathione S-transferase, C-terminal-like, protein familyQ83140012
Glutathione S-transferase, N-terminal domain, protein familyQ83166429
Prostaglandin E synthase 2, C-terminal domain, protein familyQ83167551
P129physically interacts withViroporin 3aQ88200603

Reverse relations

has part(s) (P527)
Q50262387Azurophil granule lumen proteins [azurophil granule lumen]
Q50262391Azurophil granule lumen proteins [extracellular region]
Q50264645PTGES2(88-377), PTGES3 [cytosol]

Q90038963Non-structural protein 7 [SARS-CoV-2]physically interacts withP129
Q18046593PTGES2encodesP688
Q34205586Essential 110Cys in active site of membrane-associated prostaglandin E synthase-2.main subjectP921

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