LDL receptor related protein 6

mammalian protein found in Homo sapiens

Wikidata entity: Q21132095



P682 biological process ... Q155769 (Wnt signaling pathway) Wnt signaling pathway
P682 biological process ... Q189814 (endocytosis) endocytosis
P682 biological process ... Q14633883 (regulation of transcription, DNA-templated) regulation of transcription, DNA-templated
P682 biological process ... Q14633918 (positive regulation of cell cycle) positive regulation of cell cycle
P682 biological process ... Q14645705 (multicellular organism development) multicellular organism development
P682 biological process ... Q14645729 (cerebral cortex development) cerebral cortex development
P682 biological process ... Q14762275 (canonical Wnt signaling pathway) canonical Wnt signaling pathway
P682 biological process ... Q952019 (bone remodeling) bone remodeling
P682 biological process ... Q5166400 (convergent extension) convergent extension
P682 biological process ... Q14330653 (chemical synaptic transmission) chemical synaptic transmission
P682 biological process ... Q14864051 (protein localization to plasma membrane) protein localization to plasma membrane
P682 biological process ... Q14864461 (positive regulation of DNA-binding transcription factor activity) positive regulation of DNA-binding transcription factor activity
P682 biological process ... Q14865215 (negative regulation of protein kinase activity) negative regulation of protein kinase activity
P682 biological process ... Q14873995 (negative regulation of protein serine/threonine kinase activity) negative regulation of protein serine/threonine kinase activity
P682 biological process ... Q14881721 (face morphogenesis) face morphogenesis
P682 biological process ... Q14885826 (neural tube closure) neural tube closure
P682 biological process ... Q14885862 (bone morphogenesis) bone morphogenesis
P682 biological process ... Q14885872 (primitive streak formation) primitive streak formation
P682 biological process ... Q14888070 (embryonic camera-type eye morphogenesis) embryonic camera-type eye morphogenesis
P682 biological process ... Q14890462 (cellular response to cholesterol) cellular response to cholesterol
P682 biological process ... Q14902723 (gastrulation with mouth forming second) gastrulation with mouth forming second
P682 biological process ... Q14904141 (neural crest cell differentiation) neural crest cell differentiation
P682 biological process ... Q14904256 (branching involved in mammary gland duct morphogenesis) branching involved in mammary gland duct morphogenesis
P682 biological process ... Q14905593 (dopaminergic neuron differentiation) dopaminergic neuron differentiation
P682 biological process ... Q14911597 (embryonic retina morphogenesis in camera-type eye) embryonic retina morphogenesis in camera-type eye
P682 biological process ... Q14913087 (cerebellum morphogenesis) cerebellum morphogenesis
P682 biological process ... Q15311612 (external genitalia morphogenesis) external genitalia morphogenesis
P682 biological process ... Q14818066 (positive regulation of transcription, DNA-templated) positive regulation of transcription, DNA-templated
P682 biological process ... Q14818068 (positive regulation of transcription by RNA polymerase II) positive regulation of transcription by RNA polymerase II
P682 biological process ... Q14820654 (positive regulation of cytosolic calcium ion concentration) positive regulation of cytosolic calcium ion concentration
P682 biological process ... Q14820890 (response to peptide hormone) response to peptide hormone
P682 biological process ... Q14859925 (embryonic pattern specification) embryonic pattern specification
P682 biological process ... Q14859926 (anterior/posterior pattern specification) anterior/posterior pattern specification
P682 biological process ... Q14859936 (embryonic limb morphogenesis) embryonic limb morphogenesis
P682 biological process ... Q14859940 (midbrain development) midbrain development
P682 biological process ... Q14859951 (odontogenesis of dentin-containing tooth) odontogenesis of dentin-containing tooth
P682 biological process ... Q14859978 (roof of mouth development) roof of mouth development
P682 biological process ... Q14860027 (negative regulation of canonical Wnt signaling pathway) negative regulation of canonical Wnt signaling pathway
P682 biological process ... Q14860184 (thalamus development) thalamus development
P682 biological process ... Q14860483 (positive regulation of canonical Wnt signaling pathway) positive regulation of canonical Wnt signaling pathway
P682 biological process ... Q14860865 (negative regulation of protein phosphorylation) negative regulation of protein phosphorylation
P682 biological process ... Q14863694 (negative regulation of smooth muscle cell apoptotic process) negative regulation of smooth muscle cell apoptotic process
P682 biological process ... Q21100636 (toxin transport) toxin transport
P682 biological process ... Q21106397 (receptor-mediated endocytosis involved in cholesterol transport) receptor-mediated endocytosis involved in cholesterol transport
P682 biological process ... Q21108732 (trachea cartilage morphogenesis) trachea cartilage morphogenesis
P682 biological process ... Q21109409 (Wnt signaling pathway involved in somitogenesis) Wnt signaling pathway involved in somitogenesis
P682 biological process ... Q21110820 (canonical Wnt signaling pathway involved in regulation of cell proliferation) canonical Wnt signaling pathway involved in regulation of cell proliferation
P682 biological process ... Q21111885 (Wnt signaling pathway involved in dorsal/ventral axis specification) Wnt signaling pathway involved in dorsal/ventral axis specification
P682 biological process ... Q21115824 (pericardium morphogenesis) pericardium morphogenesis
P682 biological process ... Q21115934 (axis elongation involved in somitogenesis) axis elongation involved in somitogenesis
P682 biological process ... Q21118309 (midbrain-hindbrain boundary development) midbrain-hindbrain boundary development
P682 biological process ... Q21132091 (canonical Wnt signaling pathway involved in neural crest cell differentiation) canonical Wnt signaling pathway involved in neural crest cell differentiation
P682 biological process ... Q21132092 (positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification) positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification
P682 biological process ... Q21132094 (neural crest formation) neural crest formation
P682 biological process ... Q22294691 (cell-cell adhesion) cell-cell adhesion
P682 biological process ... Q22295128 (beta-catenin destruction complex disassembly) beta-catenin destruction complex disassembly
P682 biological process ... Q24469695 (Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation) Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
P682 biological process ... Q24469699 (midbrain dopaminergic neuron differentiation) midbrain dopaminergic neuron differentiation
P681 cell component ... Q79927 (endoplasmic reticulum) endoplasmic reticulum
P681 cell component ... Q83181 (Golgi apparatus) Golgi apparatus
P681 cell component ... Q189094 (cell surface) cell surface
P681 cell component ... Q29548 (plasma membrane) plasma membrane
P681 cell component ... Q187181 (synapse) synapse
P681 cell component ... Q14645596 (extracellular region) extracellular region
P681 cell component ... Q14645696 (soma) soma
P681 cell component ... Q424178 (membrane raft) membrane raft
P681 cell component ... Q1051872 (caveola) caveola
P681 cell component ... Q14327652 (integral component of membrane) integral component of membrane
P681 cell component ... Q14349455 (membrane) membrane
P681 cell component ... Q14864702 (early endosome membrane) early endosome membrane
P681 cell component ... Q14877465 (receptor complex) receptor complex
P681 cell component ... Q14840128 (cytoplasmic vesicle) cytoplasmic vesicle
P681 cell component ... Q14860538 (early endosome) early endosome
P681 cell component ... Q22327295 (Wnt-Frizzled-LRP5/6 complex) Wnt-Frizzled-LRP5/6 complex
P681 cell component ... Q22328603 (Wnt signalosome) Wnt signalosome
P702 encoded by ... Q18028667 (LRP6) LRP6
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P527 has part(s) ... Q24723491 (EGF-like domain) EGF-like domain
P527 has part(s) ... Q24740614 (LDLR class B repeat) LDLR class B repeat
P527 has part(s) ... Q24775971 (low-density lipoprotein (LDL) receptor class A repeat) low-density lipoprotein (LDL) receptor class A repeat
P527 has part(s) ... Q24781534 (Low-density lipoprotein (LDL) receptor class A, conserved site) Low-density lipoprotein (LDL) receptor class A, conserved site
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q167149 (protein binding) protein binding
P680 molecular function ... Q14864535 (low-density lipoprotein particle receptor activity) low-density lipoprotein particle receptor activity
P680 molecular function ... Q14864747 (apolipoprotein binding) apolipoprotein binding
P680 molecular function ... Q14897646 (frizzled binding) frizzled binding
P680 molecular function ... Q14897647 (Wnt-protein binding) Wnt-protein binding
P680 molecular function ... Q14897654 (Wnt-activated receptor activity) Wnt-activated receptor activity
P680 molecular function ... Q14762994 (identical protein binding) identical protein binding
P680 molecular function ... Q14762996 (protein homodimerization activity) protein homodimerization activity
P680 molecular function ... Q14819233 (signaling receptor binding) signaling receptor binding
P680 molecular function ... Q21104715 (toxin transmembrane transporter activity) toxin transmembrane transporter activity
P680 molecular function ... Q21127034 (kinase inhibitor activity) kinase inhibitor activity
P680 molecular function ... Q21132093 (coreceptor activity involved in Wnt signaling pathway) coreceptor activity involved in Wnt signaling pathway
P680 molecular function ... Q24493361 (coreceptor activity involved in canonical Wnt signaling pathway) coreceptor activity involved in canonical Wnt signaling pathway
P361 part of ... Q24787260 (Low density lipoprotein receptor-related protein 5/6) Low density lipoprotein receptor-related protein 5/6
P361 part of ... Q24788648 (Six-bladed beta-propeller, TolB-like) Six-bladed beta-propeller, TolB-like
P361 part of ... Q41797192 (LDL receptor-like superfamily) LDL receptor-like superfamily
P361 part of ... Q83134378 (EGF-like domain, protein family) EGF-like domain, protein family
P361 part of ... Q95351433 (Low-density lipoprotein (LDL) receptor class A, conserved site, protein family) Low-density lipoprotein (LDL) receptor class A, conserved site, protein family
P361 part of ... Q95352552 (LDLR class B repeat, protein family) LDLR class B repeat, protein family
P361 part of ... Q95354109 (Low-density lipoprotein (LDL) receptor class A repeat, protein family) Low-density lipoprotein (LDL) receptor class A repeat, protein family

External Ids
P705Ensembl protein IDENSP00000445083
P705Ensembl protein IDENSP00000487008
P705Ensembl protein IDENSP00000443239
P705Ensembl protein IDENSP00000442472
P705Ensembl protein IDENSP00000486315
P705Ensembl protein IDENSP00000486383
P705Ensembl protein IDENSP00000261349
P705Ensembl protein IDENSP00000439765
P705Ensembl protein IDENSP00000486524
P705Ensembl protein IDENSP00000486758
P486MeSH descriptor IDD060488
P672MeSH tree codeD12.776.526.600
P672MeSH tree codeD12.776.543.750.710.450.500.600
P672MeSH tree codeD12.776.543.750.850.781
P638PDB structure ID4DG6
P638PDB structure ID3S94
P638PDB structure ID3S2K
P638PDB structure ID4NM5
P638PDB structure ID4NM7
P638PDB structure ID3S8V
P638PDB structure ID3SOQ
P638PDB structure ID3S8Z
P638PDB structure ID3SOB
P638PDB structure ID3SOV
P638PDB structure ID4A0P
P637RefSeq protein IDNP_002327
P637RefSeq protein IDXP_006719141
P637RefSeq protein IDXP_011518973
P2892UMLS CUIC0765067
P352UniProt protein IDO75581

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