Heat shock protein 90 alpha family class B member 1

mammalian protein found in Homo sapiens

Wikidata entity: Q21132860



P682 biological process ... Q847556 (protein folding) protein folding
P682 biological process ... Q1114520 (placenta development) placenta development
P682 biological process ... Q14358591 (xenobiotic metabolic process) xenobiotic metabolic process
P682 biological process ... Q14599533 (negative regulation of apoptotic process) negative regulation of apoptotic process
P682 biological process ... Q14633923 (protein stabilization) protein stabilization
P682 biological process ... Q26250687 (telomerase holoenzyme complex assembly) telomerase holoenzyme complex assembly
P682 biological process ... Q14758937 (positive regulation of nitric oxide biosynthetic process) positive regulation of nitric oxide biosynthetic process
P682 biological process ... Q14758939 (positive regulation of cell differentiation) positive regulation of cell differentiation
P682 biological process ... Q14761970 (positive regulation of protein kinase B signaling) positive regulation of protein kinase B signaling
P682 biological process ... Q14818037 (response to salt stress) response to salt stress
P682 biological process ... Q14819911 (response to stress) response to stress
P682 biological process ... Q14820618 (negative regulation of neuron apoptotic process) negative regulation of neuron apoptotic process
P682 biological process ... Q14820663 (positive regulation of peptidyl-serine phosphorylation) positive regulation of peptidyl-serine phosphorylation
P682 biological process ... Q14820884 (response to cocaine) response to cocaine
P682 biological process ... Q14821386 (positive regulation of protein binding) positive regulation of protein binding
P682 biological process ... Q14859934 (establishment of cell polarity) establishment of cell polarity
P682 biological process ... Q14859944 (negative regulation of proteasomal ubiquitin-dependent protein catabolic process) negative regulation of proteasomal ubiquitin-dependent protein catabolic process
P682 biological process ... Q14861556 (response to organic substance) response to organic substance
P682 biological process ... Q14862267 (positive regulation of protein serine/threonine kinase activity) positive regulation of protein serine/threonine kinase activity
P682 biological process ... Q14863968 (Fc-gamma receptor signaling pathway involved in phagocytosis) Fc-gamma receptor signaling pathway involved in phagocytosis
P682 biological process ... Q14864261 (response to unfolded protein) response to unfolded protein
P682 biological process ... Q14864992 (chaperone-mediated protein complex assembly) chaperone-mediated protein complex assembly
P682 biological process ... Q14865310 (axon extension) axon extension
P682 biological process ... Q14872982 (positive regulation of cell size) positive regulation of cell size
P682 biological process ... Q14876117 (virion attachment to host cell) virion attachment to host cell
P682 biological process ... Q14878352 (central nervous system neuron axonogenesis) central nervous system neuron axonogenesis
P682 biological process ... Q14885641 (cellular response to organic cyclic compound) cellular response to organic cyclic compound
P682 biological process ... Q14904142 (positive regulation of transforming growth factor beta receptor signaling pathway) positive regulation of transforming growth factor beta receptor signaling pathway
P682 biological process ... Q14905491 (regulation of interferon-gamma-mediated signaling pathway) regulation of interferon-gamma-mediated signaling pathway
P682 biological process ... Q14905492 (regulation of type I interferon-mediated signaling pathway) regulation of type I interferon-mediated signaling pathway
P682 biological process ... Q14906662 (regulation of protein ubiquitination) regulation of protein ubiquitination
P682 biological process ... Q14907264 (cellular response to interleukin-4) cellular response to interleukin-4
P682 biological process ... Q14911651 (neutrophil degranulation) neutrophil degranulation
P682 biological process ... Q14912124 (positive regulation of phosphoprotein phosphatase activity) positive regulation of phosphoprotein phosphatase activity
P682 biological process ... Q15315123 (telomere maintenance via telomerase) telomere maintenance via telomerase
P682 biological process ... Q21095195 (regulation of cellular response to heat) regulation of cellular response to heat
P682 biological process ... Q21101366 (negative regulation of proteasomal protein catabolic process) negative regulation of proteasomal protein catabolic process
P682 biological process ... Q21103203 (positive regulation of protein localization to cell surface) positive regulation of protein localization to cell surface
P682 biological process ... Q21104766 (positive regulation of telomerase activity) positive regulation of telomerase activity
P682 biological process ... Q21109407 (negative regulation of protein metabolic process) negative regulation of protein metabolic process
P682 biological process ... Q21132859 (supramolecular fiber organization) supramolecular fiber organization
P682 biological process ... Q21172369 (positive regulation of tau-protein kinase activity) positive regulation of tau-protein kinase activity
P682 biological process ... Q21172571 (negative regulation of complement-dependent cytotoxicity) negative regulation of complement-dependent cytotoxicity
P682 biological process ... Q22245275 (positive regulation of cyclin-dependent protein kinase activity) positive regulation of cyclin-dependent protein kinase activity
P682 biological process ... Q22302363 (negative regulation of transforming growth factor beta activation) negative regulation of transforming growth factor beta activation
P681 cell component ... Q79899 (cytoplasm) cytoplasm
P681 cell component ... Q189094 (cell surface) cell surface
P681 cell component ... Q220599 (cytosol) cytosol
P681 cell component ... Q29548 (plasma membrane) plasma membrane
P681 cell component ... Q39572 (mitochondrion) mitochondrion
P681 cell component ... Q40260 (nucleus) nucleus
P681 cell component ... Q903634 (extracellular exosome) extracellular exosome
P681 cell component ... Q1065756 (melanosome) melanosome
P681 cell component ... Q1308970 (inclusion body) inclusion body
P681 cell component ... Q3824358 (intracellular anatomical structure) intracellular anatomical structure
P681 cell component ... Q14330632 (perinuclear region of cytoplasm) perinuclear region of cytoplasm
P681 cell component ... Q14349455 (membrane) membrane
P681 cell component ... Q14645596 (extracellular region) extracellular region
P681 cell component ... Q22327681 (sperm head plasma membrane) sperm head plasma membrane
P681 cell component ... Q22328083 (ficolin-1-rich granule lumen) ficolin-1-rich granule lumen
P681 cell component ... Q22329455 (ooplasm) ooplasm
P681 cell component ... Q14645696 (soma) soma
P681 cell component ... Q14758893 (secretory granule lumen) secretory granule lumen
P681 cell component ... Q14817956 (nucleoplasm) nucleoplasm
P681 cell component ... Q14819446 (apical plasma membrane) apical plasma membrane
P681 cell component ... Q14864700 (basolateral plasma membrane) basolateral plasma membrane
P681 cell component ... Q14865309 (axonal growth cone) axonal growth cone
P681 cell component ... Q14878285 (lysosomal membrane) lysosomal membrane
P681 cell component ... Q14884512 (brush border membrane) brush border membrane
P681 cell component ... Q14905184 (COP9 signalosome) COP9 signalosome
P681 cell component ... Q14907952 (dendritic growth cone) dendritic growth cone
P681 cell component ... Q14916314 (aryl hydrocarbon receptor complex) aryl hydrocarbon receptor complex
P681 cell component ... Q21116517 (HSP90-CDC37 chaperone complex) HSP90-CDC37 chaperone complex
P681 cell component ... Q22325163 (protein-containing complex) protein-containing complex
P702 encoded by ... Q18027382 (HSP90AB1) HSP90AB1
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P527 has part(s) ... Q24766624 (Heat shock protein Hsp90, N-terminal) Heat shock protein Hsp90, N-terminal
P527 has part(s) ... Q24780207 (Histidine kinase/HSP90-like ATPase domain) Histidine kinase/HSP90-like ATPase domain
P527 has part(s) ... Q24786251 (Heat shock protein Hsp90, conserved site) Heat shock protein Hsp90, conserved site
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q167149 (protein binding) protein binding
P680 molecular function ... Q14330639 (RNA binding) RNA binding
P680 molecular function ... Q14633869 (ubiquitin protein ligase binding) ubiquitin protein ligase binding
P680 molecular function ... Q14633870 (peptide binding) peptide binding
P680 molecular function ... Q14633875 (unfolded protein binding) unfolded protein binding
P680 molecular function ... Q27123456 (disordered domain specific binding) disordered domain specific binding
P680 molecular function ... Q14762994 (identical protein binding) identical protein binding
P680 molecular function ... Q14762996 (protein homodimerization activity) protein homodimerization activity
P680 molecular function ... Q14817981 (ATP binding) ATP binding
P680 molecular function ... Q14817984 (protein kinase binding) protein kinase binding
P680 molecular function ... Q14860365 (nucleotide binding) nucleotide binding
P680 molecular function ... Q14860389 (ATP-dependent protein binding) ATP-dependent protein binding
P680 molecular function ... Q14860860 (tau protein binding) tau protein binding
P680 molecular function ... Q14861864 (protein dimerization activity) protein dimerization activity
P680 molecular function ... Q14863341 (GTP binding) GTP binding
P680 molecular function ... Q14864244 (kinase binding) kinase binding
P680 molecular function ... Q14865546 (nitric-oxide synthase regulator activity) nitric-oxide synthase regulator activity
P680 molecular function ... Q14865603 (histone deacetylase binding) histone deacetylase binding
P680 molecular function ... Q14866204 (double-stranded RNA binding) double-stranded RNA binding
P680 molecular function ... Q14873292 (cadherin binding) cadherin binding
P680 molecular function ... Q14883313 (protein kinase regulator activity) protein kinase regulator activity
P680 molecular function ... Q14901685 (transmembrane transporter binding) transmembrane transporter binding
P680 molecular function ... Q14905394 (heat shock protein binding) heat shock protein binding
P680 molecular function ... Q14914594 (DNA polymerase binding) DNA polymerase binding
P680 molecular function ... Q14916132 (dATP binding) dATP binding
P680 molecular function ... Q21095634 (MHC class II protein complex binding) MHC class II protein complex binding
P680 molecular function ... Q21105009 (TPR domain binding) TPR domain binding
P680 molecular function ... Q21114239 (histone methyltransferase binding) histone methyltransferase binding
P680 molecular function ... Q21115406 (UTP binding) UTP binding
P680 molecular function ... Q21132858 (CTP binding) CTP binding
P680 molecular function ... Q22312818 (sulfonylurea receptor binding) sulfonylurea receptor binding
P361 part of ... Q24723191 (Ribosomal protein S5 domain 2-type fold) Ribosomal protein S5 domain 2-type fold
P361 part of ... Q24772687 (heat shock protein Hsp90 family) heat shock protein Hsp90 family
P361 part of ... Q41797986 (Histidine kinase/HSP90-like ATPase superfamily) Histidine kinase/HSP90-like ATPase superfamily
P361 part of ... Q41798277 (HSP90, C-terminal domain) HSP90, C-terminal domain
P361 part of ... Q83138175 (Heat shock protein Hsp90, N-terminal domain, protein family) Heat shock protein Hsp90, N-terminal domain, protein family
P361 part of ... Q83164586 (Histidine kinase/HSP90-like ATPase family) Histidine kinase/HSP90-like ATPase family
P361 part of ... Q95352107 (Heat shock protein Hsp90, conserved site, protein family) Heat shock protein Hsp90, conserved site, protein family
P129 physically interacts with ... Q10859697 (luminespib) luminespib

External Ids
P705Ensembl protein IDENSP00000325875
P705Ensembl protein IDENSP00000481908
P705Ensembl protein IDENSP00000360709
P705Ensembl protein IDENSP00000360609
P638PDB structure ID3NMQ
P638PDB structure ID1UYM
P638PDB structure ID1QZ2
P638PDB structure ID2L6J
P638PDB structure ID3FWV
P638PDB structure ID3PRY
P638PDB structure ID3UQ3
P638PDB structure ID5FWK
P638PDB structure ID5FWL
P638PDB structure ID5FWM
P637RefSeq protein IDNP_001258898
P637RefSeq protein IDNP_001258899
P637RefSeq protein IDNP_001258900
P637RefSeq protein IDNP_001258901
P637RefSeq protein IDNP_001358167
P637RefSeq protein IDNP_031381
P352UniProt protein IDP08238

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