Structural basis for the dsRNA specificity of the Lassa virus NP exonuclease

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Structural basis for the dsRNA specificity of the Lassa virus NP exonuclease is …
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scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...744211H
P356DOI10.1371/JOURNAL.PONE.0044211
P932PMC publication ID3429428
P698PubMed publication ID22937163
P5875ResearchGate publication ID230769894

P50authorKathryn M HastieQ96243727
Michelle A ZandonattiQ96243728
Erica Ollmann SaphireQ28320547
P2093author name stringLiam B King
P2860cites workExcision of 3' termini by the Trex1 and TREX2 3'-->5' exonucleases. Characterization of the recombinant proteinsQ24291054
The human interferon- and estrogen-regulated ISG20/HEM45 gene product degrades single-stranded RNA and DNA in vitroQ24291320
Innate immune recognition of viral infectionQ24498364
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Structural basis for proofreading during replication of the Escherichia coli chromosomeQ27638768
The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partneringQ27643804
Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW DomainsQ27644048
Structural basis for translation termination on the 70S ribosomeQ27651016
Cap binding and immune evasion revealed by Lassa nucleoprotein structureQ27665958
Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppressionQ27666703
Structure of DNA polymerase I Klenow fragment bound to duplex DNAQ27732134
Features and development of CootQ27861079
The human TREX2 3' -> 5'-exonuclease structure suggests a mechanism for efficient nonprocessive DNA catalysisQ28303398
Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencingQ33576672
Crystal structure of human ISG20, an interferon-induced antiviral ribonucleaseQ34365279
Discovery of an RNA virus 3'->5' exoribonuclease that is critically involved in coronavirus RNA synthesisQ34596952
DNA binding induces active site conformational change in the human TREX2 3'-exonucleaseQ37169783
DNA substrate structural requirements for the exonuclease and polymerase activities of procaryotic and phage DNA polymerasesQ38345051
Physiological and immunologic disturbances associated with shock in a primate model of Lassa feverQ40799148
Differential inhibition of type I interferon induction by arenavirus nucleoproteinsQ41937252
Specificity and enzymatic mechanism of the editing exonuclease of Escherichia coli DNA polymerase IIIQ44604513
Identification of a new motif required for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I (Klenow fragment): the RRRY motif is necessary for the binding of single-stranded DNA substrate and the template strand of the mismatchedQ81191858
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectLassa virusQ1806636
P304page(s)e44211
P577publication date2012-01-01
P1433published inPLOS OneQ564954
P1476titleStructural basis for the dsRNA specificity of the Lassa virus NP exonuclease
P478volume7

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cites work (P2860)
Q56909960Current research for a vaccine against Lassa hemorrhagic fever virus
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Q30238887Immunobiology of Ebola and Lassa virus infections
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Q36753696Influence of RNA Binding on the Structure and Dynamics of the Lassa Virus Nucleoprotein
Q50238755Interactome analysis of the lymphocytic choriomeningitis virus nucleoprotein in infected cells reveals ATPase Na+/K+ transporting subunit Alpha 1 and prohibitin as host-cell factors involved in the life cycle of mammarenaviruses.
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