SUFU negative regulator of hedgehog signaling

mammalian protein found in Homo sapiens

Wikidata entity: Q21173255



P682 biological process ... Q33123 (proteolysis) proteolysis
P682 biological process ... Q828130 (signal transduction) signal transduction
P682 biological process ... Q14599571 (skin development) skin development
P682 biological process ... Q14633878 (negative regulation of transcription by RNA polymerase II) negative regulation of transcription by RNA polymerase II
P682 biological process ... Q14633883 (regulation of transcription, DNA-templated) regulation of transcription, DNA-templated
P682 biological process ... Q14645705 (multicellular organism development) multicellular organism development
P682 biological process ... Q14859912 (heart looping) heart looping
P682 biological process ... Q14859931 (spinal cord dorsal/ventral patterning) spinal cord dorsal/ventral patterning
P682 biological process ... Q14860466 (skeletal system development) skeletal system development
P682 biological process ... Q14863100 (negative regulation of DNA-binding transcription factor activity) negative regulation of DNA-binding transcription factor activity
P682 biological process ... Q14885826 (neural tube closure) neural tube closure
P682 biological process ... Q14886461 (smoothened signaling pathway involved in ventral spinal cord interneuron specification) smoothened signaling pathway involved in ventral spinal cord interneuron specification
P682 biological process ... Q14886462 (smoothened signaling pathway involved in spinal cord motor neuron cell fate specification) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
P682 biological process ... Q14886893 (negative regulation of smoothened signaling pathway) negative regulation of smoothened signaling pathway
P682 biological process ... Q14897896 (negative regulation of osteoblast differentiation) negative regulation of osteoblast differentiation
P682 biological process ... Q14910939 (negative regulation of protein import into nucleus) negative regulation of protein import into nucleus
P682 biological process ... Q14911565 (coronary vasculature development) coronary vasculature development
P682 biological process ... Q14914559 (cytoplasmic sequestering of transcription factor) cytoplasmic sequestering of transcription factor
P682 biological process ... Q21095348 (determination of left/right symmetry) determination of left/right symmetry
P682 biological process ... Q21101535 (ventricular septum development) ventricular septum development
P682 biological process ... Q21103310 (aorta development) aorta development
P682 biological process ... Q21105138 (negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning) negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
P682 biological process ... Q21106970 (negative regulation of ubiquitin-dependent protein catabolic process) negative regulation of ubiquitin-dependent protein catabolic process
P681 cell component ... Q180436 (cilium) cilium
P681 cell component ... Q79899 (cytoplasm) cytoplasm
P681 cell component ... Q220599 (cytosol) cytosol
P681 cell component ... Q40260 (nucleus) nucleus
P681 cell component ... Q21095118 (ciliary tip) ciliary tip
P681 cell component ... Q21095125 (ciliary base) ciliary base
P702 encoded by ... Q17145556 (SUFU) SUFU
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P527 has part(s) ... Q24724610 (Suppressor of fused-like domain) Suppressor of fused-like domain
P527 has part(s) ... Q24775830 (Suppressor of fused C-terminal) Suppressor of fused C-terminal
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q14817982 (transcription factor binding) transcription factor binding
P680 molecular function ... Q14817984 (protein kinase binding) protein kinase binding
P680 molecular function ... Q14820643 (signal transducer activity) signal transducer activity
P680 molecular function ... Q167149 (protein binding) protein binding
P680 molecular function ... Q14864664 (transcription corepressor activity) transcription corepressor activity
P680 molecular function ... Q14872998 (beta-catenin binding) beta-catenin binding
P361 part of ... Q24781142 (Suppressor of fused, eukaryotic) Suppressor of fused, eukaryotic
P361 part of ... Q41798266 (Suppressor of fused, N-terminal) Suppressor of fused, N-terminal
P361 part of ... Q54444051 (Suppressor of fused, C-terminal domain superfamily) Suppressor of fused, C-terminal domain superfamily
P361 part of ... Q83134730 (Suppressor of fused-like domain, protein family) Suppressor of fused-like domain, protein family
P361 part of ... Q83145666 (Suppressor of fused C-terminal domain, protein family) Suppressor of fused C-terminal domain, protein family
P279 subclass of ... Q8054 (protein) protein

External Ids
P705Ensembl protein IDENSP00000358915
P705Ensembl protein IDENSP00000411597
P705Ensembl protein IDENSP00000358918
P638PDB structure ID4BLD
P638PDB structure ID4BL8
P638PDB structure ID4BLB
P638PDB structure ID4BL9
P638PDB structure ID4KMH
P638PDB structure ID4KM9
P638PDB structure ID1M1L
P638PDB structure ID4BLA
P638PDB structure ID4KM8
P638PDB structure ID4KMD
P637RefSeq protein IDNP_001171604
P637RefSeq protein IDNP_057253
P637RefSeq protein IDXP_011538160
P637RefSeq protein IDXP_011538162
P637RefSeq protein IDXP_011538163
P637RefSeq protein IDXP_011538165
P637RefSeq protein IDXP_011538166
P637RefSeq protein IDXP_016871812
P352UniProt protein IDQ9UMX1

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