Role of gonadotropin-releasing hormone (GnRH) in ovarian cancer

scientific article published on October 7, 2003

Role of gonadotropin-releasing hormone (GnRH) in ovarian cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1010340839
P356DOI10.1186/1477-7827-1-65
P953full work available at URLhttps://europepmc.org/articles/PMC239893
https://rbej.biomedcentral.com/track/pdf/10.1186/1477-7827-1-65
https://europepmc.org/articles/PMC239893?pdf=render
P3181OpenCitations bibliographic resource ID5016554
P932PMC publication ID239893
P698PubMed publication ID14594454
P5875ResearchGate publication ID9030168

P50authorCarsten GründkerQ104131351
P2093author name stringGünter Emons
P2860cites workLHRH might act as a negative autocrine regulator of proliferation of human ovarian cancerQ22254198
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A gonadotropin-releasing hormone (GnRH) receptor specific for GnRH II in primatesQ28188845
A transcriptionally active human type II gonadotropin-releasing hormone receptor gene homolog overlaps two genes in the antisense orientation on chromosome 1q.12Q28204330
Expression of gonadotropin-releasing hormone II (GnRH-II) receptor in human endometrial and ovarian cancer cells and effects of GnRH-II on tumor cell proliferationQ28206472
Photoaffinity labelling of gonadotropin releasing hormone binding sites in human epithelial ovarian carcinomataQ28342702
A novel mammalian receptor for the evolutionarily conserved type II GnRHQ28345646
Involvement of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase in alpha1B-adrenergic receptor/Galphaq-induced inhibition of cell proliferationQ32126818
The nucleotide sequences of human GnRH receptors in breast and ovarian tumors are identical with that found in pituitaryQ34293507
Biology of the gonadotropin-releasing hormone system in gynecological cancersQ34467231
Inhibition of human epithelial ovarian cancer cell growth in vitro by agonistic and antagonistic analogues of luteinizing hormone-releasing hormoneQ35068355
Inhibition of growth of OV-1063 human epithelial ovarian cancer xenografts in nude mice by treatment with luteinizing hormone-releasing hormone antagonist SB-75.Q35614963
Identification of the second gonadotropin-releasing hormone in chicken hypothalamus: evidence that gonadotropin secretion is probably controlled by two distinct gonadotropin-releasing hormones in avian speciesQ36263472
Effects of epidermal growth factor and analogues of luteinizing hormone-releasing hormone and somatostatin on phosphorylation and dephosphorylation of tyrosine residues of specific protein substrates in various tumorsQ37412449
Regulation of luteinizing hormone-releasing hormone receptor binding by heterologous and autologous receptor-stimulated tyrosine phosphorylationQ37432455
Expression of the messenger RNAs for luteinizing hormone-releasing hormone (LHRH) and its receptor in human ovarian epithelial carcinoma.Q38298792
Antiproliferative effects of luteinizing hormone-releasing hormone (LHRH) agonists on human androgen-independent prostate cancer cell line DU 145: evidence for an autocrine-inhibitory LHRH loop.Q38305783
Presence of gonadotropin-releasing hormone and its messenger ribonucleic acid in human ovarian epithelial carcinomaQ38316634
Expression and signal transduction pathways of gonadotropin-releasing hormone receptorsQ40519029
Hypothalamic hormones: from neuroendocrinology to cancer therapy.Q40682650
Antiproliferative signaling of luteinizing hormone-releasing hormone in human endometrial and ovarian cancer cells through G protein alpha(I)-mediated activation of phosphotyrosine phosphataseQ40805639
Luteinizing hormone-releasing hormone agonist triptorelin and antagonist cetrorelix inhibit EGF-induced c-fos expression in human gynecological cancersQ40864187
Luteinizing hormone-releasing hormone as an autocrine growth factor in ES-2 ovarian cancer cell line.Q40887346
Role of growth factors, steroid and peptide hormones in the regulation of human prostatic tumor growth.Q40971129
Involvement of annexin V in antiproliferative effects of gonadotropin-releasing hormone agonists on human endometrial cancer cell lineQ41097193
Luteinizing hormone-releasing hormone antagonist Cetrorelix (SB-75) and bombesin antagonist RC-3940-II inhibit the growth of androgen-independent PC-3 prostate cancer in nude miceQ41097702
Inhibition of growth of androgen-independent DU-145 prostate cancer in vivo by luteinising hormone-releasing hormone antagonist Cetrorelix and bombesin antagonists RC-3940-II and RC-3950-II.Q41105921
The expression of gonadotropin-releasing hormone and its receptor in endometrial cancer, and its relevance as an autocrine growth factor.Q41203834
Growth inhibition of human prostate tumor cells by an agonist of gonadotrophin-releasing hormoneQ41354135
Inhibition of growth of human ovarian cancer in nude mice by luteinizing hormone-releasing hormone antagonist Cetrorelix (SB-75).Q41372843
Direct growth inhibition of human endometrial cancer cells by the gonadotropin-releasing hormone antagonist SB-75: role of apoptosisQ41496310
Lupron retards proliferation of ovarian epithelial tumor cells cultured in serum-free mediumQ41685614
Gonadotropin-releasing hormone analogues inhibit cell proliferation and activate signal transduction pathways in MDA-MB-231 human breast cancer cell lineQ41703246
The effects of gonadotrophin releasing hormone analogues in prostate cancer are mediated through specific tumour receptorsQ41729614
Differential regulation of two forms of gonadotropin-releasing hormone messenger ribonucleic acid in human granulosa-luteal cellsQ42498122
Luteinizing hormone-releasing hormone antagonists interfere with autocrine and paracrine growth stimulation of MCF-7 mammary cancer cells by insulin-like growth factorsQ42509019
Protein kinase C-independent stimulation of activator protein-1 and c-Jun N-terminal kinase activity in human endometrial cancer cells by the LHRH agonist triptorelinQ43807625
Luteinizing hormone-releasing hormone induces JunD-DNA binding and extends cell cycle in human ovarian cancer cellsQ44021000
Expression of receptors for luteinizing hormone-releasing hormone in human ovarian and endometrial cancers: frequency, autoregulation, and correlation with direct antiproliferative activity of luteinizing hormone-releasing hormone analoguesQ45712994
Phosphotyrosine phosphatase-activity in membranes from endometrial carcinomaQ47756941
Luteinizing hormone-releasing hormone agonist triptorelin antagonizes signal transduction and mitogenic activity of epidermal growth factor in human ovarian and endometrial cancer cell lines.Q47763136
Fas and Fas ligand system may mediate antiproliferative activity of gonadotropin-releasing hormone receptor in endometrial cancer cells.Q47977493
Effects of GnRH analogs on six ovarian cancer cell lines in cultureQ48094405
Regional expression of mRNA encoding a second form of gonadotropin-releasing hormone in the macaque brainQ48251675
Primary structure and biological activity of a third gonadotropin-releasing hormone from lamprey brainQ48324176
Evidence for tight coupling of gonadotropin-releasing hormone receptor to stimulated Fas ligand expression in reproductive tract tumors: possible mechanism for hormonal control of apoptotic cell death.Q53727336
Growth of human breast cancer cells inhibited by a luteinizing hormone-releasing hormone agonistQ59065919
Gonadotropin releasing hormone binding sites in human epithelial ovarian carcinomataQ69492544
Evidence for coupling of phosphotyrosine phosphatase to gonadotropin-releasing hormone receptor in ovarian carcinoma membraneQ71079605
Effect of gonadotropin-releasing hormone analogs and their conjugates on gonadotropin-releasing hormone receptor--positive human cancer cell linesQ71254335
Coupling of gonadotropin-releasing hormone receptor to Gi protein in human reproductive tract tumorsQ71477174
Luteinizing hormone-releasing hormone agonists interfere with the stimulatory actions of epidermal growth factor in human prostatic cancer cell lines, LNCaP and DU 145Q71788622
Differentially regulated immediate early genes in the rat uterusQ72315037
High affinity binding and direct antiproliferative effects of LHRH analogues in human ovarian cancer cell linesQ72559548
High affinity binding and direct antiproliferative effects of luteinizing hormone-releasing hormone analogs in human endometrial cancer cell linesQ72662186
The use of luteinizing hormone releasing hormone agonists and antagonists in gynaecological cancersQ72810392
Luteinizing hormone-releasing hormone induces nuclear factor kappaB-activation and inhibits apoptosis in ovarian cancer cellsQ73148506
Frequent expression of Fas in gonadotropin-releasing hormone receptor-bearing tumorsQ73556567
Regulation of UT-OC-3 ovarian carcinoma cells by cytokines: inhibitory effects on cell proliferation and activation of transcription factors AP-1 and NF-kappaBQ73645052
Effects of LHRH agonists on the growth of human prostatic tumor cells: "in vitro" and "in vivo" studiesQ73936293
Mechanisms mediating multiple physiological responses to gonadotropin-releasing hormoneQ77718861
Growth-inhibitory actions of analogues of Luteinizing Hormone Releasing Hormone on tumor cellsQ81066875
Treatment with luteinizing-hormone-releasing hormone antagonist sb-75 decreases levels of epidermal growth-factor receptor and its messenger-RNA in ov-1063 human epithelial ovarian-cancer xenografts in nude-miceQ84074281
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectovarian cancerQ172341
endocrinologyQ162606
hormoneQ11364
peptideQ172847
reproductive medicineQ351870
nerve tissue proteinQ6996861
ovarian neoplasmQ11793790
P304page(s)65
P577publication date2003-10-07
P1433published inReproductive Biology and EndocrinologyQ15767218
P1476titleRole of gonadotropin-releasing hormone (GnRH) in ovarian cancer
P478volume1

Reverse relations

cites work (P2860)
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