The Renin-Angiotensin-aldosterone system in vascular inflammation and remodeling

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The Renin-Angiotensin-aldosterone system in vascular inflammation and remodeling is …
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P356DOI10.1155/2014/689360
P8608Fatcat IDrelease_7qv7z22wcze3blyb4nyqlvqtdm
P3181OpenCitations bibliographic resource ID1308160
P932PMC publication ID3997861
P698PubMed publication ID24804145
P5875ResearchGate publication ID262113601

P50authorMaricica PacurariQ28050515
Paul B TchounwouQ59817484
P2093author name stringKenneth Ndebele
Ramzi Kafoury
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Angiotensin II induces vascular cell adhesion molecule-1 expression in rat vasculature: A potential link between the renin-angiotensin system and atherosclerosisQ78253256
Aliskiren-associated acute kidney injury in a patient with pre-existing chronic kidney disease and dilated cardiomyopathyQ82732434
Aliskiren inhibits atherosclerosis development and improves plaque stability in APOE*3Leiden.CETP transgenic mice with or without treatment with atorvastatinQ82769267
IκBNS regulates interleukin-6 production and inhibits neointimal formation after vascular injury in miceQ82773601
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Aldosterone impairs bone marrow-derived progenitor cell formation.Q53611018
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Potentiation of endothelium-dependent relaxations to bradykinin by angiotensin I converting enzyme inhibitors in canine coronary artery involves both endothelium-derived relaxing and hyperpolarizing factorsQ54267978
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Widespread tissue distribution of human chymaseQ72616829
Effect of angiotensin-(1-7) and bradykinin in patients with heart failure treated with an ACE inhibitorQ72997576
Direct proinflammatory effect of C-reactive protein on human endothelial cellsQ73134567
Overexpression of tumor necrosis factor-alpha produces an increase in lung volumes and pulmonary hypertensionQ73335421
Lack of TNF-alpha attenuates intimal hyperplasia after mouse carotid artery injuryQ74472245
Angiotensin II induces interleukin-6 transcription in vascular smooth muscle cells through pleiotropic activation of nuclear factor-kappa B transcription factorsQ77215422
Circulating cell adhesion molecules are correlated with ultrasound-based assessment of carotid atherosclerosisQ77544912
Angiotensin II stimulates endothelial vascular cell adhesion molecule-1 via nuclear factor-kappaB activation induced by intracellular oxidative stressQ28372941
Aldosterone induces vascular insulin resistance by increasing insulin-like growth factor-1 receptor and hybrid receptorQ28573287
Colocalization and release of angiotensin and renin in renal cortical cellsQ30311510
(Pro)renin receptor contributes to diabetic nephropathy by enhancing renal inflammationQ30433027
Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cellsQ30462210
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Valsartan for prevention of restenosis after stenting of type B2/C lesions: the VAL-PREST trial.Q31929933
Autocrine and paracrine function of Angiotensin 1-7 in tissue repair during hypertensionQ33598406
Multiple autocrine growth factors modulate vascular smooth muscle cell growth response to angiotensin II.Q33900223
C-reactive protein-mediated vascular injury requires complement.Q33961757
Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells.Q34106420
Aliskiren displays long-lasting interactions with human reninQ34109516
Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor toneQ34378188
Aldosterone Enhances IGF-I-Mediated Signaling and Biological Function in Vascular Smooth Muscle CellsQ34392644
Pathophysiology of coronary artery diseaseQ34429470
Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors.Q34608252
Tumor necrosis factor-α signaling in macrophages.Q34734335
Impairment of endothelial progenitor cell function and vascularization capacity by aldosterone in mice and humansQ34981416
Vasoactive substances: nitric oxide and endothelial dysfunction in atherosclerosisQ35027751
Towards the understanding of the local hematopoietic bone marrow renin-angiotensin systemQ35099152
Activation of the NF-kappa B and I kappa B system in smooth muscle cells after rat arterial injury. Induction of vascular cell adhesion molecule-1 and monocyte chemoattractant protein-1.Q35763936
Antiatherogenic effects of L-arginine in the hypercholesterolemic rabbitQ35822869
NADPH oxidase-derived H(2)O(2) contributes to angiotensin II-induced aldosterone synthesis in human and rat adrenal cortical cellsQ36001842
Endothelial function and dysfunction. Part II: Association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial Factors of the European Society of HypertensionQ36015782
Effect of Alzheimer caregiving on circulating levels of C-reactive protein and other biomarkers relevant to cardiovascular disease risk: a longitudinal studyQ36182377
STUDIES ON EXPERIMENTAL HYPERTENSION : I. THE PRODUCTION OF PERSISTENT ELEVATION OF SYSTOLIC BLOOD PRESSURE BY MEANS OF RENAL ISCHEMIA.Q36254330
The liver as the site of C-reactive protein formationQ36267987
Effects of aldosterone on the vasculatureQ36375830
Pathophysiological regulation of the AT1-receptor and implications for vascular diseaseQ36443428
Role of the renin-angiotensin-aldosterone system and proinflammatory mediators in cardiovascular diseaseQ36511499
Functional mineralocorticoid receptors in human vascular endothelial cells regulate intercellular adhesion molecule-1 expression and promote leukocyte adhesionQ37003229
Recent advances in the angiotensin-converting enzyme 2-angiotensin(1-7)-Mas axis.Q37098279
Renin-angiotensin system revisitedQ37269647
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Inflammation in cardiovascular disease: cart, horse, or both?Q48018364
Angiotensin-converting enzyme 2 and angiotensin-(1-7): an evolving story in cardiovascular regulationQ48561334
Theodore Cooper Lecture: Tissue angiotensin and pathobiology of vascular disease: a unifying hypothesisQ48577521
In vivo blockade of tumor necrosis factor-alpha accelerates functional endothelial recovery after balloon angioplasty.Q50503323
Aldosterone antagonism or synthase inhibition reduces end-organ damage induced by treatment with angiotensin and high saltQ37406166
Toll-like receptor 4 contributes to blood pressure regulation and vascular contraction in spontaneously hypertensive ratsQ37731722
Have the renin-angiotensin-aldosterone system perturbations in cardiovascular disease been exhausted?Q37786566
Endothelial Damage and Regeneration: The Role of the Renin-Angiotensin-Aldosterone SystemQ37812341
Angiotensin converting enzyme inhibitors effect on endothelial dysfunction: a meta-analysis of randomised controlled trialsQ37853688
Mineralocorticoid receptors in vascular function and diseaseQ37896953
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Targeting the aldosterone pathway in cardiovascular disease.Q37951665
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Effects of a novel aldosterone synthase inhibitor for treatment of primary hypertension: results of a randomized, double-blind, placebo- and active-controlled phase 2 trialQ38483164
The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signalingQ38571062
Discovery of (3S,3aR)-2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic acid (PF-3882845), an orally efficacious mineralocorticoid receptor (MR) antagonist for hypertension and nephropathy.Q39673573
The renin-angiotensin system (first of two parts).Q39901718
Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE-/- miceQ39937826
Investigation of aldosterone-synthase inhibition in ratsQ40326702
Reversal of left ventricular hypertrophy in essential hypertension. A meta-analysis of randomized double-blind studiesQ40982204
Interleukin-6 overexpression induces pulmonary hypertensionQ41056520
Effect of vasoactive peptides on prostacyclin synthesis in man.Q41776050
C-reactive protein attenuates endothelial progenitor cell survival, differentiation, and function: further evidence of a mechanistic link between C-reactive protein and cardiovascular disease.Q42460041
Mineralocorticoid receptor-mediated DNA damage in kidneys of DOCA-salt hypertensive ratsQ42785218
Aldosterone synthase inhibition with LCI699: a proof-of-concept study in patients with primary aldosteronismQ42908792
Olmesartan inhibits angiotensin II-Induced migration of vascular smooth muscle cells through Src and mitogen-activated protein kinase pathwaysQ43052006
Treatment with telmisartan attenuates graft arteriosclerosis in murine cardiac allograftsQ43203856
Small artery remodeling is the most prevalent (earliest?) form of target organ damage in mild essential hypertensionQ43630782
In vitro evidence for an intracellular site of angiotensin actionQ43819699
A specific binding site for the prorenin propart peptide Arg10-Arg20 does not occur on human endothelial cellsQ43856359
Study of aldosterone synthase inhibition as an add-on therapy in resistant hypertensionQ44119714
Presence of cellular renin-angiotensin system in chromaffin cells of bovine adrenal medullaQ44182982
Eplerenone in Patients with Systolic Heart Failure and Mild SymptomsQ44272913
C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscleQ44382946
Angiotensin II receptor blocker valsartan suppresses reactive oxygen species generation in leukocytes, nuclear factor-kappa B, in mononuclear cells of normal subjects: evidence of an antiinflammatory actionQ44582536
Cooperative interaction between reactive oxygen species and Ca2+ signals contributes to angiotensin II-induced hypertrophy in adult rat cardiomyocytesQ44636719
Improvement in endothelial progenitor cells from peripheral blood by ramipril therapy in patients with stable coronary artery diseaseQ44960467
Fluvastatin enhances the inhibitory effects of a selective AT1 receptor blocker, valsartan, on atherosclerosisQ45081308
Angiotensin-(1-7) attenuates neointimal formation after stent implantation in the rat.Q45151827
Irbesartan and lipoic acid improve endothelial function and reduce markers of inflammation in the metabolic syndrome: results of the Irbesartan and Lipoic Acid in Endothelial Dysfunction (ISLAND) studyQ45227732
The angiotensin II receptor blocker candesartan cilexetil reduces neointima proliferation after coronary stent implantation: a prospective randomized study under intravascular ultrasound guidanceQ45230899
Antisense oligodeoxynucleotide inhibition of vascular angiotensin-converting enzyme expression attenuates neointimal formation: evidence for tissue angiotensin-converting enzyme functionQ45866740
Comparative effects of aliskiren-based and ramipril-based therapy on the renin system during long-term (6 months) treatment and withdrawal in patients with hypertension.Q45925622
Stimulation of endothelial progenitor cells: a new putative therapeutic effect of angiotensin II receptor antagonistsQ46378624
AliskirenQ46434761
Aldosterone synthase inhibition improves cardiovascular function and structure in rats with heart failure: a comparison with spironolactoneQ46513264
A one-year study of the antiatherosclerotic effect of the angiotensin-II receptor blocker losartan in hypertensive patients. A comparison with angiotension-converting enzyme inhibitorsQ46687545
Role of aldosterone in angiotensin II-induced cardiac and aortic inflammation, fibrosis, and hypertrophyQ46878366
Losartan improves resistance artery lesions and prevents CTGF and TGF-beta production in mild hypertensive patientsQ46947467
Design, synthesis, and structure-activity relationships of dihydrofuran-2-one and dihydropyrrol-2-one derivatives as novel benzoxazin-3-one-based mineralocorticoid receptor antagonistsQ47746698
Direct evidence of leukocyte adhesion in arterioles by angiotensin II.Q47882328
Inflammatory markers are associated with left ventricular hypertrophy and diastolic dysfunction in a population-based sample of elderly men and womenQ48017162
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
P304page(s)689360
P577publication date2014-01-01
P1433published inInternational Journal of InflammationQ26854008
P1476titleThe Renin-Angiotensin-aldosterone system in vascular inflammation and remodeling
P478volume2014

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