| protein | Q8054 |
| P682 | biological process | cell cycle | Q188941 |
| human ageing | Q332154 | ||
| regulation of gene expression | Q411391 | ||
| autophagy of mitochondrion | Q1806192 | ||
| protein sumoylation | Q3503705 | ||
| cellular senescence | Q9075999 | ||
| apoptotic process | Q14599311 | ||
| negative regulation of cell population proliferation | Q14599399 | ||
| negative regulation of cell growth | Q14599698 | ||
| regulation of transcription, DNA-templated | Q14633883 | ||
| positive regulation of gene expression | Q14633893 | ||
| negative regulation of transcription, DNA-templated | Q14633919 | ||
| protein stabilization | Q14633923 | ||
| glucose homeostasis | Q14758934 | ||
| transcription, DNA-templated | Q14763010 | ||
| rRNA transcription | Q14818035 | ||
| positive regulation of apoptotic process | Q14818063 | ||
| positive regulation of transcription, DNA-templated | Q14818066 | ||
| positive regulation of transcription by RNA polymerase II | Q14818068 | ||
| G1/S transition of mitotic cell cycle | Q21095333 | ||
| regulation of cyclin-dependent protein serine/threonine kinase activity | Q21105499 | ||
| regulation of protein targeting to mitochondrion | Q21106655 | ||
| negative regulation of ubiquitin-dependent protein catabolic process | Q21106970 | ||
| regulation of apoptotic DNA fragmentation | Q21109161 | ||
| positive regulation of signal transduction by p53 class mediator | Q21110449 | ||
| negative regulation of proteolysis involved in cellular protein catabolic process | Q21110450 | ||
| negative regulation of hepatocyte proliferation | Q21113971 | ||
| negative regulation of ubiquitin protein ligase activity | Q22245593 | ||
| negative regulation of protein neddylation | Q22245766 | ||
| replicative senescence | Q14818090 | ||
| negative regulation of NF-kappaB transcription factor activity | Q14819252 | ||
| response to organic cyclic compound | Q14820916 | ||
| activation of cysteine-type endopeptidase activity involved in apoptotic process | Q14860870 | ||
| protein destabilization | Q14860896 | ||
| epidermis development | Q14863096 | ||
| protein polyubiquitination | Q14863376 | ||
| regulation of protein stability | Q14863403 | ||
| protein K63-linked ubiquitination | Q14864250 | ||
| response to organonitrogen compound | Q14864433 | ||
| negative regulation of B cell proliferation | Q14864446 | ||
| positive regulation of DNA-binding transcription factor activity | Q14864461 | ||
| somatic stem cell population maintenance | Q14864652 | ||
| negative regulation of mammary gland epithelial cell proliferation | Q14864733 | ||
| negative regulation of protein kinase activity | Q14865215 | ||
| cellular response to hydrogen peroxide | Q14865235 | ||
| negative regulation of cyclin-dependent protein serine/threonine kinase activity | Q14865553 | ||
| positive regulation of DNA damage response, signal transduction by p53 class mediator | Q14872804 | ||
| negative regulation of cell cycle | Q14873927 | ||
| rRNA processing | Q14877433 | ||
| negative regulation of immature T cell proliferation in thymus | Q14877480 | ||
| positive regulation of protein localization to nucleus | Q14878792 | ||
| regulation of protein export from nucleus | Q14882512 | ||
| negative regulation of cell-matrix adhesion | Q14889734 | ||
| mitochondrial depolarization | Q14901963 | ||
| negative regulation of phosphorylation | Q14902450 | ||
| negative regulation of ubiquitin-protein transferase activity | Q14904372 | ||
| positive regulation of apoptotic process involved in mammary gland involution | Q14904932 | ||
| positive regulation of protein sumoylation | Q14905273 | ||
| apoptotic mitochondrial changes | Q14905376 | ||
| negative regulation of protein binding | Q14905380 | ||
| regulation of G2/M transition of mitotic cell cycle | Q14907002 | ||
| somatic stem cell division | Q14907006 | ||
| positive regulation of cellular senescence | Q14907008 | ||
| regulation of nucleocytoplasmic transport | Q14907027 | ||
| amyloid fibril formation | Q21095286 | ||
| P681 | cell component | nucleolus | Q30869 |
| mitochondrion | Q39572 | ||
| nucleus | Q40260 | ||
| cytoplasm | Q79899 | ||
| nucleoplasm | Q14817956 | ||
| nuclear body | Q14817965 | ||
| protein-containing complex | Q22325163 | ||
| senescence-associated heterochromatin focus | Q14906999 | ||
| granular component | Q14907017 | ||
| P702 | encoded by | Cdkn2a | Q14907011 |
| P703 | found in taxon | house mouse | Q83310 |
| P680 | molecular function | protein binding | Q167149 |
| DNA binding | Q14633858 | ||
| p53 binding | Q14817974 | ||
| DNA-binding transcription factor activity | Q14817979 | ||
| transcription factor binding | Q14817982 | ||
| protein kinase binding | Q14817984 | ||
| protein N-terminus binding | Q14817992 | ||
| MDM2/MDM4 family protein binding | Q14817995 | ||
| cyclin-dependent protein serine/threonine kinase inhibitor activity | Q21095643 | ||
| ubiquitin ligase inhibitor activity | Q24496236 | ||
| disordered domain specific binding | Q27123456 | ||
| NF-kappaB binding | Q14865606 | ||
| ubiquitin-protein transferase inhibitor activity | Q14907000 | ||
| SUMO transferase activity | Q15333157 | ||
| P361 | part of | tumor suppressor ARF | Q24774050 |
| Q28506253 | A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1 |
| Q28506702 | ARF impedes NPM/B23 shuttling in an Mdm2-sensitive tumor suppressor pathway |
| Q28593886 | Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis |
| Q28590239 | Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53. |
| Q34183797 | Bidirectional autoregulatory mechanism of metastasis-associated protein 1-alternative reading frame pathway in oncogenesis |
| Q24303502 | CARF is a novel protein that cooperates with mouse p19ARF (human p14ARF) in activating p53 |
| Q28512180 | Cloning and characterization of murine p16INK4a and p15INK4b genes |
| Q28510551 | Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation |
| Q28507075 | Defining the molecular basis of Arf and Hdm2 interactions |
| Q24307490 | Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity |
| Q28513259 | Effect of 9p21.3 coronary artery disease locus neighboring genes on atherosclerosis in mice |
| Q28585867 | Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis |
| Q24658265 | Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression |
| Q28511962 | Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice |
| Q24652510 | Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6 |
| Q28589317 | Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7 gamma |
| Q28593126 | Nucleophosmin is required for DNA integrity and p19Arf protein stability |
| Q24321834 | PTEN regulation by Akt-EGR1-ARF-PTEN axis |
| Q28205682 | Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway |
| Q27682111 | Structural polymorphism in the N-terminal oligomerization domain of NPM1 |
| Q24292042 | TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence |
| Q28509972 | The ARF tumor suppressor inhibits BCL6-mediated transcriptional repression |
| Q28592198 | The Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformation |
| Q24305067 | The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein |
| Q28587433 | The ink4a/arf tumor suppressors cooperate with p21cip1/waf in the processes of mouse epidermal differentiation, senescence, and carcinogenesis |
| Q28504995 | c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expression |
| Q24564901 | p19ARF determines the balance between normal cell proliferation rate and apoptosis during mammary gland development |
| Q14907011 | Cdkn2a | encodes | P688 |
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