riociguat

chemical compound

Wikidata entity: Q2154494

C₂₀H₁₉FN₈O₂ (P274)


Wikimedia Commons category is Riociguat



Quantities

P4250defined daily dose4.5
P2067mass422.1615

P3780 active ingredient in ... Q29004385 (Adempas) Adempas
P233 canonical SMILES String CN(C1=C(N=C(N=C1N)C2=NN(C3=C2C=CC=N3)CC4=CC=CC=C4F)N)C(=O)OC ???
P373 Commons category String Riociguat ???
P366 has use ... Q12140 (medication) medication
P31 instance of ... Q113145171 (type of chemical entity) type of chemical entity
P3493 legal status (medicine) ... Q879952 (boxed warning) boxed warning
P8026 LiverTox likelihood score ... Q83284667 (LiverTox toxicity likelihood category E) LiverTox toxicity likelihood category E
P2175 medical condition treated ... Q1128595 (pulmonary hypertension) pulmonary hypertension
P2175 medical condition treated ... Q18554296 (chronic pulmonary heart disease) chronic pulmonary heart disease
P129 physically interacts with ... Q21110352 (Guanylate cyclase 1 soluble subunit alpha 2) Guanylate cyclase 1 soluble subunit alpha 2
P129 physically interacts with ... Q21110359 (Guanylate cyclase 1 soluble subunit beta 1) Guanylate cyclase 1 soluble subunit beta 1
P3489 pregnancy category ... Q3679561 (Australian pregnancy category X) Australian pregnancy category X
P3489 pregnancy category ... Q28123619 (US pregnancy category X) US pregnancy category X
P769 significant drug interaction ... Q162867 (nitroglycerin) nitroglycerin
P769 significant drug interaction ... Q179748 (isosorbide dinitrate) isosorbide dinitrate
P769 significant drug interaction ... Q191521 (sildenafil) sildenafil
P769 significant drug interaction ... Q424156 (tadalafil) tadalafil
P769 significant drug interaction ... Q424161 (vardenafil) vardenafil
P769 significant drug interaction ... Q1243800 (isosorbide) isosorbide
P769 significant drug interaction ... Q2873270 (avanafil) avanafil
P279 subclass of ... Q11173 (chemical compound) chemical compound
P2868 subject has role ... Q422816 (enzyme activator) enzyme activator
P2275 World Health Organisation international non-proprietary name Monolingualtext riociguat ???

External Ids
P267ATC codeC02KX05
P231CAS Registry Number625115-55-1
P683ChEBI ID76018
P592ChEMBL IDCHEMBL2107834
P661ChemSpider ID9479719
P715DrugBank IDDB08931
P11198DrugCentral ID4807
P8494DSSTOX compound identifierDTXCID901405436
P3117DSSTox substance IDDTXSID50978109
P232EC number641-755-1
P2566ECHA Substance Infocard ID100.169.606
P646Freebase ID/m/05zkh4w
P595Guide to Pharmacology Ligand ID5257
P2057Human Metabolome Database IDHMDB0257236
P234InChIInChI=1S/C20H19FN8O2/c1-28(20(30)31-2)15-16(22)25-18(26-17(15)23)14-12-7-5-9-24-19(12)29(27-14)10-11-6-3-4-8-13(11)21/h3-9H,10H2,1-2H3,(H4,22,23,25,26)
P235InChIKeyWXXSNCNJFUAIDG-UHFFFAOYSA-N
P665KEGG IDD09572
P7830LiverTox IDRiociguat
P10245MedlinePlus drug identifiera615005
P486MeSH descriptor IDC542595
P6366Microsoft Academic ID (discontinued)2776304953
P2115NDF-RT IDN0000188995
P10283OpenAlex IDC2776304953
P11199Probes And Drugs IDPD009166
P662PubChem CID11304743
P1579Reaxys registry number12581953
P3345RxNorm CUI1439816
P2877SureChEMBL ID245457
P2892UMLS CUIC2717561
P2892UMLS CUIC2717562
P11089UniChem compound ID1076305
P652UNIIRU3FE2Y4XI
P11143WikiProjectMed IDRiociguat

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