Linking chronic infection and autoimmune diseases: Mycobacterium avium subspecies paratuberculosis, SLC11A1 polymorphisms and type-1 diabetes mellitus

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Linking chronic infection and autoimmune diseases: Mycobacterium avium subspecies paratuberculosis, SLC11A1 polymorphisms and type-1 diabetes mellitus is …
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scholarly articleQ13442814

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P819ADS bibcode2009PLoSO...4.7109P
P356DOI10.1371/JOURNAL.PONE.0007109
P932PMC publication ID2740822
P698PubMed publication ID19768110
P5875ResearchGate publication ID26825555

P50authorNiyaz AhmedQ7042059
Stefania ZanettiQ102065333
Daniela PaccagniniQ28833442
Maria GazouliQ30247981
Speranza MasalaQ30430525
P2093author name stringAdolfo Pacifico
Leonardo A Sechi
Valentina Rosu
John Ikonomopoulos
Lee Sieswerda
P2860cites workDetection and Isolation of Mycobacterium avium subspecies paratuberculosis from intestinal mucosal biopsies of patients with and without Crohn's disease in SardiniaQ81900636
Genomic organization and sequence of the human NRAMP gene: identification and mapping of a promoter region polymorphismQ24654959
Divalent cation transport and susceptibility to infectious and autoimmune disease: continuation of the Ity/Lsh/Bcg/Nramp1/Slc11a1 gene storyQ28203008
Environmental triggers and determinants of type 1 diabetesQ28283357
Type 1 diabetesQ28301396
Slc11a1 enhances the autoimmune diabetogenic T-cell response by altering processing and presentation of pancreatic islet antigensQ28585423
Genetic regulation of macrophage activation: understanding the function of Nramp1 (=Ity/Lsh/Bcg)Q28592471
Nonobese diabetic mouse congenic analysis reveals chromosome 11 locus contributing to diabetes susceptibility, macrophage STAT5 dysfunction, and granulocyte-macrophage colony-stimulating factor overproductionQ30440604
Specific immunoassays confirm association of Mycobacterium avium Subsp. paratuberculosis with type-1 but not type-2 diabetes mellitus.Q30858199
The Nramp1 protein and its role in resistance to infection and macrophage function.Q33694066
Mycobacteria and other environmental organisms as immunomodulators for immunoregulatory disorders.Q34303951
Mechanisms of disease: the hygiene hypothesis revisited.Q34652218
NRAMP1 gene polymorphisms in patients with rheumatoid arthritis in KoreansQ34656623
Environmental factors in the etiology of type 1 diabetesQ34737247
Susceptibility to mycobacterial infections: the importance of host geneticsQ35069566
Johne's disease, inflammatory bowel disease, and Mycobacterium paratuberculosisQ35919853
Humoral immune responses of type 1 diabetes patients to Mycobacterium avium subsp. paratuberculosis lend support to the infectious trigger hypothesis.Q36452334
Variations in the NRAMP1 gene and susceptibility to tuberculosis in West AfricansQ38901256
Mycobacterium avium subspecies paratuberculosis is not associated with type-2 diabetes mellitusQ42171590
Relationship between Crohn's disease, infection with Mycobacterium avium subspecies paratuberculosis and SLC11A1 gene polymorphisms in Sardinian patientsQ42269266
Nramp1-mediated innate resistance to intraphagosomal pathogens is regulated by IRF-8, PU.1, and Miz-1.Q42798379
Susceptibility to leprosy may be conditioned by an interaction between the NRAMP1 promoter polymorphisms and the lepromin responseQ43319874
SLC11A1 (Formerly NRAMP1) gene polymorphisms associated with pediatric tuberculosis in ChinaQ43605707
Paratuberculosis and Type I diabetes: is this the trigger?Q44197410
In vivo RNA interference demonstrates a role for Nramp1 in modifying susceptibility to type 1 diabetes.Q46583266
Promoter polymorphism of SLC11A1 (formerly NRAMP1) confers susceptibility to autoimmune type 1 diabetes mellitus in JapaneseQ48025145
Natural resistance-associated macrophage protein 1 gene polymorphisms in rheumatoid arthritis.Q53845999
Functional polymorphism in Z-DNA-forming motif of promoter of SLC11A1 gene and type 1 diabetes in Japanese subjects: association study and meta-analysis.Q53858590
Genetic analysis of SLC11A1 polymorphisms in multiple sclerosis patients.Q53877621
Susceptibility to leprosy is linked to the human NRAMP1 gene.Q54150836
Fms-like tyrosine kinase 3 ligand administration overcomes a genetically determined dendritic cell deficiency in NOD mice and protects against diabetes developmentQ57134204
The natural resistance-associated macrophage protein gene is associated with Crohn's diseaseQ73676287
Splenic macrophages from the NOD mouse are defective in the ability to present antigenQ77087686
Does cross-reactivity between mycobacterium avium paratuberculosis and human intestinal antigens characterize Crohn's disease?Q79871772
Mycobacterium avium subspecies paratuberculosis bacteremia in type 1 diabetes mellitus: an infectious trigger?Q80435310
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P407language of work or nameEnglishQ1860
P921main subjecttype-1 diabetesQ124407
Mycobacterium avium aviumQ310728
P304page(s)e7109
P577publication date2009-01-01
P1433published inPLOS OneQ564954
P1476titleLinking chronic infection and autoimmune diseases: Mycobacterium avium subspecies paratuberculosis, SLC11A1 polymorphisms and type-1 diabetes mellitus
P478volume4

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cites work (P2860)
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Q34064846Antibodies recognizing Mycobacterium avium paratuberculosis epitopes cross-react with the beta-cell antigen ZnT8 in Sardinian type 1 diabetic patients
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