Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs

scientific article

Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PMED.0020295
P3181OpenCitations bibliographic resource ID3322633
P932PMC publication ID1240050
P698PubMed publication ID16231975
P5875ResearchGate publication ID7534456

P50authorPeter J. HotezQ7174738
Maria Elena BottazziQ28817215
Ricardo T. FujiwaraQ30513841
Alex LoukasQ30513842
Bin ZhanQ85367926
Jeffrey Michael BethonyQ96097192
Gaddam Narsa GoudQ114780932
Najju RanjitQ114780933
P2093author name stringKaren Jones
Susana Mendez
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The Ingestion of Red Blood Cells by Schistosoma mansoniQ54247460
Emerging Patterns of Hookworm Infection: Influence of Aging on the Intensity ofNecatorInfection in Hainan Province, People’s Republic of ChinaQ56420614
IgG1/IgG2 antibody dichotomy in sera of vaccinated or naturally infected dogs with visceral leishmaniosisQ60227749
Comparison of whole blood and purified canine lymphocytes in a lymphocyte-stimulation microassayQ67324088
Persistence of Immunity Following Double Vaccination of Pups with X-Irradiated Ancylostoma caninum LarvaeQ72632064
Effect of age of the dog on immunogenic efficiency of double vaccination with x-irradiated Ancylostoma caninum larvaeQ72701710
The hookworm platelet inhibitor: functional blockade of integrins GPIIb/IIIa (alphaIIbbeta3) and GPIa/IIa (alpha2beta1) inhibits platelet aggregation and adhesion in vitroQ77223499
Successful vaccination of BALB/c mice against human hookworm (Necator americanus): the immunological phenotype of the protective responseQ78840455
Intersection of HIV and Anemia in women of reproductive age: a 10-year analysis of three Zimbabwe demographic health surveys, 2005-2015Q104755510
Ancylostoma caninum anticoagulant peptide: a hookworm-derived inhibitor of human coagulation factor Xa.Q34196787
Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine InitiativeQ34246851
Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes the fecundity and growth of wormsQ34318119
Vaccination against gastrointestinal nematode parasites of ruminants using gut-expressed antigensQ34346516
Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trialsQ34438394
Mathematical modelling of schistosomiasis japonica: comparison of control strategies in the People's Republic of China.Q34646760
The immunobiology of schistosomiasisQ34718128
Helminth vaccines: from mining genomic information for vaccine targets to systems used for protein expressionQ35143303
Digestive proteases of blood-feeding nematodes.Q35212643
The nature and prospects for gut membrane proteins as vaccine candidates for Haemonchus contortus and other ruminant trichostrongyloidsQ35295051
Hookworm infection: new developments and prospects for controlQ35881138
Immunobiology of hookworm infectionQ36024402
Salmonella typhimurium as a basis for a live oral Echinococcus granulosus vaccineQ38307642
Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animalsQ38906805
Vaccination with irradiated Ancylostoma caninum third stage larvae induces a Th2 protective response in dogsQ39013779
Cloning, yeast expression, isolation, and vaccine testing of recombinant Ancylostoma-secreted protein (ASP)-1 and ASP-2 from Ancylostoma ceylanicumQ39030027
Effect of vaccination with a recombinant fusion protein encoding an astacinlike metalloprotease (MTP-1) secreted by host-stimulated Ancylostoma caninum third-stage infective larvaeQ39078494
Effect of vaccinations with recombinant fusion proteins on Ancylostoma caninum habitat selection in the canine intestineQ39078499
Effect of combining the larval antigens Ancylostoma secreted protein 2 (ASP-2) and metalloprotease 1 (MTP-1) in protecting hamsters against hookworm infection and disease caused by Ancylostoma ceylanicumQ39244367
The nature and causes of "hookworm anemia".Q40042892
Hookworm control as a strategy to prevent iron deficiencyQ41582192
Evolutionary and biomedical implications of a Schistosoma japonicum complementary DNA resource.Q42608417
Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashionQ42693655
Rate of reinfection with intestinal nematodes after treatment of children with mebendazole or albendazole in a highly endemic area.Q43954184
Vaccination of calves against Ostertagia ostertagi with cysteine proteinase enriched protein fractionsQ44024611
A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria. RTS,S Malaria Vaccine Evaluation GroupQ44174498
Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificityQ44432211
Metalloendopeptidases from the intestinal brush border of Haemonchus contortus as protective antigens for sheepQ44594907
Protection against systemic candidiasis in mice immunized with secreted aspartic proteinase 2.Q44792128
Aspartyl proteases from the intestinal brush border of Haemonchus contortus as protective antigens for sheepQ44821782
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P921main subjecthookworm diseaseQ5898175
P304page(s)e295
P577publication date2005-10-01
P1433published inPLOS MEDICINEQ1686921
P1476titleVaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs
P478volume2

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