scholarly article | Q13442814 |
P819 | ADS bibcode | 2010PNAS..10714903J |
P356 | DOI | 10.1073/PNAS.1008990107 |
P953 | full work available at URL | http://www.pnas.org/content/107/33/14903.full.pdf |
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20668238/?tool=EBI | ||
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20668238/pdf/?tool=EBI | ||
https://europepmc.org/articles/PMC2930420 | ||
https://europepmc.org/articles/PMC2930420?pdf=render | ||
https://doi.org/10.1073/pnas.1008990107 | ||
https://pnas.org/doi/pdf/10.1073/pnas.1008990107 | ||
P3181 | OpenCitations bibliographic resource ID | 578283 |
P932 | PMC publication ID | 2930420 |
P698 | PubMed publication ID | 20668238 |
P5875 | ResearchGate publication ID | 45406610 |
P50 | author | Gideon Bollag | Q61518938 |
Barry S Taylor | Q88249464 | ||
Christine A Pratilas | Q102380741 | ||
P2093 | author name string | Neal Rosen | |
Agnes Viale | |||
Feng Xing | |||
Weiqing Wang | |||
James Tsai | |||
Ensar Halilovic | |||
David B. Solit | |||
Madhavi Tadi | |||
Yogindra Persaud | |||
Poulikos I. Poulikakos | |||
Paul B. Chapman | |||
Eric W. Joseph | |||
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Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways | Q24309037 | ||
Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism | Q24633458 | ||
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Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity | Q24652600 | ||
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Phase I pharmacokinetic and pharmacodynamic study of the oral, small-molecule mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) in patients with advanced cancers | Q27851426 | ||
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PIK3CA mutation uncouples tumor growth and cyclin D1 regulation from MEK/ERK and mutant KRAS signaling | Q35227481 | ||
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(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway | Q37112466 | ||
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BRAF V600E disrupts AZD6244-induced abrogation of negative feedback pathways between extracellular signal-regulated kinase and Raf proteins | Q39954401 | ||
Biological characterization of ARRY-142886 (AZD6244), a potent, highly selective mitogen-activated protein kinase kinase 1/2 inhibitor | Q40164535 | ||
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Paradoxical activation of Raf by a novel Raf inhibitor | Q40939473 | ||
Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma | Q42723115 | ||
A negative feedback signaling network underlies oncogene-induced senescence | Q43116108 | ||
Phase I pharmacokinetic and pharmacodynamic study of the oral MAPK/ERK kinase inhibitor PD-0325901 in patients with advanced cancers | Q43136770 | ||
Flow cytometric analysis of G1- and G2/M-phase subpopulations in mammalian cell nuclei using side scatter and DNA content measurements | Q44825483 | ||
BRAF and RAS mutations in human lung cancer and melanoma | Q78598197 | ||
P433 | issue | 33 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 14903–14908 | |
P577 | publication date | 2010-07-28 | |
2010-08-01 | |||
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner | |
P478 | volume | 107 |