Fibroblast growth factor 2

mammalian protein found in Mus musculus

Fibroblast growth factor 2 is …
instance of (P31):
proteinQ8054

sublass of (P279):
proteinQ8054

External links are
P705Ensembl protein IDENSMUSP00000037694
ENSMUSP00000088742
ENSMUSP00000103755
ENSMUSP00000122227
ENSMUSP00000143094
P637RefSeq protein IDNP_032032
XP_006535462
XP_036018787
P352UniProt protein IDP15655

P682biological processhuman ageingQ332154
angiogenesisQ539568
cell differentiationQ210861
wound healingQ1509074
lung developmentQ14327711
glial cell differentiationQ14330978
negative regulation of cell population proliferationQ14599399
positive regulation of blood vessel endothelial cell migrationQ14904590
positive regulation of endothelial cell chemotaxisQ14905262
positive regulation of cell migration involved in sprouting angiogenesisQ14905605
positive regulation of DNA biosynthetic processQ14906203
substantia nigra developmentQ14914352
positive regulation of cell fate specificationQ14916209
chondroblast differentiationQ21095686
negative regulation of fibroblast migrationQ21103080
positive regulation of endothelial cell chemotaxis to fibroblast growth factorQ21154393
regulation of endothelial cell chemotaxis to fibroblast growth factorQ21157889
growth factor dependent regulation of skeletal muscle satellite cell proliferationQ21173181
inositol phosphate biosynthetic processQ21173182
positive regulation of sprouting angiogenesisQ21173183
positive regulation of vascular associated smooth muscle cell proliferationQ22305572
positive regulation of vascular endothelial cell proliferationQ27862112
positive regulation of cell population proliferationQ14633891
positive regulation of gene expressionQ14633893
multicellular organism developmentQ14645705
positive regulation of cell differentiationQ14758939
positive regulation of protein kinase B signalingQ14761970
positive regulation of phosphatidylinositol 3-kinase activityQ14762273
positive regulation of transcription, DNA-templatedQ14818066
positive regulation of transcription by RNA polymerase IIQ14818068
embryo development ending in birth or egg hatchingQ14818115
regulation of cell cycleQ14818129
positive regulation of cell divisionQ14819260
positive regulation of protein phosphorylationQ14819846
negative regulation of cell deathQ14819896
positive regulation of epithelial cell proliferationQ14820076
positive regulation of ERK1 and ERK2 cascadeQ14821388
response to axon injuryQ14852020
branching involved in ureteric bud morphogenesisQ14859588
positive regulation of endothelial cell migrationQ14859610
stem cell developmentQ14859975
positive regulation of cerebellar granule cell precursor proliferationQ14860185
positive regulation of canonical Wnt signaling pathwayQ14860483
regulation of retinal cell programmed cell deathQ14863326
positive regulation of osteoblast differentiationQ14863698
positive regulation of smooth muscle cell proliferationQ14863701
angiogenesis involved in coronary vascular morphogenesisQ14863999
negative regulation of wound healingQ14864137
fibroblast growth factor receptor signaling pathwayQ14864684
positive regulation of MAP kinase activityQ14864686
positive regulation of endothelial cell proliferationQ14865064
positive regulation of cardiac muscle cell proliferationQ14865337
regulation of signaling receptor activityQ14865464
positive regulation of angiogenesisQ14865470
organ inductionQ14866192
cell migration involved in sprouting angiogenesisQ14866194
phosphatidylinositol biosynthetic processQ14866196
paracrine signalingQ14873666
hyaluronan catabolic processQ14880367
release of sequestered calcium ion into cytosolQ14885200
cardiac muscle cell proliferationQ14889336
mammary gland epithelial cell differentiationQ14890117
negative regulation of blood vessel endothelial cell migrationQ14890428
positive regulation of phospholipase C activityQ14902301
corticotropin hormone secreting cell differentiationQ14903142
thyroid-stimulating hormone-secreting cell differentiationQ14903143
positive chemotaxisQ14903362
P681cell componentnucleusQ40260
cytoplasmQ79899
extracellular spaceQ1385443
extracellular regionQ14645596
P702encoded byFgf2Q18250571
P703found in taxonhouse mouseQ83310
P680molecular functionprotein bindingQ167149
integrin bindingQ14633861
receptor-receptor interactionQ27862885
heparin bindingQ14819453
growth factor activityQ14820601
cytokine activityQ14862699
fibroblast growth factor receptor bindingQ14866183
nuclear receptor coactivator activityQ14866186
chemoattractant activityQ14866188
P361part offibroblast growth factor 2Q24722430
Cytokine IL1/FGFQ24738677

Reverse relations

main subject (P921)
Q24313578Aminopeptidase A is a functional target in angiogenic blood vessels
Q28586566Angiogenic factors stimulate tubular branching morphogenesis of sonic hedgehog-deficient lungs
Q24623508Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo
Q28506952Antagonistic interactions between FGF and BMP signaling pathways: a mechanism for positioning the sites of tooth formation
Q28591929C3G regulates the size of the cerebral cortex neural precursor population
Q28587327Caveolin-1 knockout mice show an impaired angiogenic response to exogenous stimuli
Q24305494Characterization of FGFRL1, a novel fibroblast growth factor (FGF) receptor preferentially expressed in skeletal tissues
Q28586621Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog
Q24314782Crucial role of vHNF1 in vertebrate hepatic specification
Q47035981Defects in chondrocyte maturation and secondary ossification in mouse knee joint epiphyses due to Snorc deficiency.
Q28263694Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2)
Q28591023Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung
Q28585880Efficient suppression of FGF-2-induced ERK activation by the cooperative interaction among mammalian Sprouty isoforms
Q28589436FGF2-induced upregulation of DNA polymerase-delta p12 subunit in endothelial cells
Q28240993Fibroblast growth factor (FGF) 18 signals through FGF receptor 3 to promote chondrogenesis
Q28507347Fibroblast growth factor (FGF)-2 and FGF receptor 3 are required for the development of the substantia nigra, and FGF-2 plays a crucial role for the rescue of dopaminergic neurons after 6-hydroxydopamine lesion
Q28511435Fibroblast growth factor receptor signaling promotes radial glial identity and interacts with Notch1 signaling in telencephalic progenitors
Q28594385Fibroblast growth factor signaling regulates pillar cell development in the organ of corti
Q28508681Functions of fibroblast growth factor (FGF)-2 and FGF-5 in astroglial differentiation and blood-brain barrier permeability: evidence from mouse mutants
Q28587566Gli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation
Q28587724Id genes are direct targets of bone morphogenetic protein induction in embryonic stem cells
Q28512657Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviors
Q28511748Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary
Q28507096Msx1 controls inductive signaling in mammalian tooth morphogenesis
Q51736417Negative regulation of lens fiber cell differentiation by RTK antagonists Spry and Spred.
Q24322602Neurofibroma-associated growth factors activate a distinct signaling network to alter the function of neurofibromin-deficient endothelial cells
Q28505506Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor
Q28512644Neurotrophic signaling in normal and degenerating rodent retinas
Q28593957Protease nexin-1 is expressed at the mouse met-/mesencephalic junction and FGF signaling regulates its promoter activity in primary met-/mesencephalic cells
Q28587821Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesis
Q28511512Regulation of neuronal death and calcitonin gene-related peptide by fibroblast growth factor-2 and FGFR3 after peripheral nerve injury: evidence from mouse mutants
Q28506891Shox2-deficient mice exhibit a rare type of incomplete clefting of the secondary palate
Q28589855The int-2 gene product acts as a growth factor and substitutes for basic fibroblast growth factor in promoting the differentiation of a normal mouse mammary epithelial cell line
Q24307092Wnt regulation of progenitor maturation in the cortex depends on Shh or fibroblast growth factor 2

Q18250571Fgf2encodesP688

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