Unconventional myosin-VI

mouse protein (annotated by UniProtKB/Swiss-Prot Q64331)

Unconventional myosin-VI is …
instance of (P31):
proteinQ8054

External links are
P638PDB structure ID3H8D
2KIA
2LD3
P352UniProt protein IDQ64331

P682biological processhearingQ160289
endocytosisQ189814
protein targetingQ658882
transportQ1435575
synapse assemblyQ1813773
DNA damage response, signal transduction by p53 class mediatorQ14818045
positive regulation of transcription by RNA polymerase IIQ14818068
inner ear developmentQ14859973
protein transportQ14860325
chemical synaptic transmissionQ14330653
dendrite developmentQ14330983
locomotory behaviorQ14645719
regulation of synaptic plasticityQ14863046
glutamate secretionQ14863319
inner ear morphogenesisQ14877676
inner ear auditory receptor cell differentiationQ14914030
cellular response to electrical stimulusQ21106175
regulation of secretionQ21110850
cell-cell adhesionQ22294691
P681cell componentplasma membraneQ29548
cytoplasmQ79899
nucleusQ40260
Golgi apparatusQ83181
axonQ178999
synapseQ187181
nuclear membraneQ465608
extracellular exosomeQ903634
brush borderQ2462753
cytoplasmic vesicleQ14840128
perinuclear region of cytoplasmQ14330632
membraneQ14349455
cell projectionQ14353100
neuronal cell bodyQ14645696
nucleoplasmQ14817956
ruffleQ14860430
filamentous actinQ14860437
clathrin-coated pitQ14860540
vesicle membraneQ14863961
clathrin-coated endocytic vesicleQ14875721
myosin complexQ14876102
RNA polymerase II, holoenzymeQ21110340
P702encoded byMyo6Q18252547
P703found in taxonhouse mouseQ83310
P527has part(s)Myosin, N-terminal, SH3-likeQ24723982
Myosin head, motor domainQ24780076
Myosin VI, cargo binding domainQ24781775
Class VI myosin, motor domainQ41797243
P680molecular functionprotein bindingQ167149
ATP bindingQ14817981
calmodulin bindingQ14819275
nucleotide bindingQ14860365
actin filament bindingQ14860806
actin bindingQ14863962
cytoskeletal motor activityQ14876109
cadherin binding involved in cell-cell adhesionQ22312562
P361part ofP-loop containing nucleoside triphosphate hydrolaseQ24726930
Myosin S1 fragment, N-terminalQ24770780
kinesin motor domain superfamilyQ41798053
Myosin, N-terminal, SH3-like, protein familyQ83134652
Myosin head, motor domain, protein familyQ83147134
Myosin VI, cargo binding domain, protein familyQ83162716
Class VI myosin, motor domain, protein familyQ83170794

Reverse relations

main subject (P921)
Q28507258A PDZ-binding motif as a critical determinant of Rho guanine exchange factor function and cell phenotype
Q28510685A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function
Q24678935A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis
Q28510749BDNF-mediated neurotransmission relies upon a myosin VI motor complex
Q28510182Cochlear developmental defect and background-dependent hearing thresholds in the Jackson circler (jc) mutant mouse
Q28513897Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development
Q34135553Deciphering the structure and function of Als2cr4 in the mouse retina
Q28511940GLUT1CBP(TIP2/GIPC1) interactions with GLUT1 and myosin VI: evidence supporting an adapter function for GLUT1CBP
Q24535864MYO6, the human homologue of the gene responsible for deafness in Snell's waltzer mice, is mutated in autosomal dominant nonsyndromic hearing loss
Q24634356Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes
Q39801019Myosin VI is required for the proper maturation and function of inner hair cell ribbon synapses
Q28585164Role of myosin VI in the differentiation of cochlear hair cells
Q72951118Snell's waltzer, a new mutation affecting behaviour and the inner ear in the mouse
Q28513409The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells
Q28591364The small GTPase Rac1 regulates auditory hair cell morphogenesis

Q18252547Myo6encodesP688

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