| scholarly article | Q13442814 |
| P2093 | author name string | Keqiang Ye | |
| Chi Bun Chan | |||
| Chaoyang Liu | |||
| P2860 | cites work | 7,8-Dihydroxyflavone, a small molecule TrkB agonist, improves spatial memory and increases thin spine density in a mouse model of Alzheimer disease-like neuronal loss | Q21090643 |
| Post-injury treatment with 7,8-dihydroxyflavone, a TrkB receptor agonist, protects against experimental traumatic brain injury via PI3K/Akt signaling | Q21559447 | ||
| A de novo mutation affecting human TrkB associated with severe obesity and developmental delay | Q24307838 | ||
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| A Synthetic 7,8-Dihydroxyflavone Derivative Promotes Neurogenesis and Exhibits Potent Antidepressant Effect | Q28298196 | ||
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| 7,8-dihydroxyflavone, a TrkB receptor agonist, blocks long-term spatial memory impairment caused by immobilization stress in rats | Q28566697 | ||
| Protection of spiral ganglion neurons from degeneration using small-molecule TrkB receptor agonists | Q30443252 | ||
| 7,8,3'-Trihydroxyflavone, a potent small molecule TrkB receptor agonist, protects spiral ganglion neurons from degeneration both in vitro and in vivo | Q30453707 | ||
| A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone. | Q33664194 | ||
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| Flavonoid fisetin promotes ERK-dependent long-term potentiation and enhances memory | Q34000281 | ||
| Advances in flavonoid research since 1992. | Q34114197 | ||
| Neurotrophins protect against cytosine arabinoside-induced apoptosis of immature rat cerebellar neurons | Q45165094 | ||
| 7,8-Dihydroxyflavone leads to survival of cultured embryonic motoneurons by activating intracellular signaling pathways. | Q45964298 | ||
| NGF signals through TrkA to increase clathrin at the plasma membrane and enhance clathrin-mediated membrane trafficking. | Q45987073 | ||
| Activation of pro-survival Akt and ERK1/2 signalling pathways underlie the anti-apoptotic effects of flavanones in cortical neurons. | Q46931456 | ||
| BDNF gene-modified mesenchymal stem cells promote functional recovery and reduce infarct size in the rat middle cerebral artery occlusion model. | Q47226339 | ||
| Intravenous brain-derived neurotrophic factor reduces infarct size and counterregulates Bax and Bcl-2 expression after temporary focal cerebral ischemia | Q47230275 | ||
| Adenovirus vector-mediated in vivo gene transfer of brain-derived neurotrophic factor (BDNF) promotes rubrospinal axonal regeneration and functional recovery after complete transection of the adult rat spinal cord | Q47680168 | ||
| Social interaction rescues memory deficit in an animal model of Alzheimer's disease by increasing BDNF-dependent hippocampal neurogenesis. | Q48248565 | ||
| Design of Potent Peptide Mimetics of Brain-derived Neurotrophic Factor | Q48318337 | ||
| Activation of TrkB by 7,8-dihydroxyflavone prevents fear memory defects and facilitates amygdalar synaptic plasticity in aging | Q48468543 | ||
| Novel monocyclic and bicyclic loop mimetics of brain-derived neurotrophic factor | Q48551074 | ||
| Hyperexcitability in combined entorhinal/hippocampal slices of adult rat after exposure to brain-derived neurotrophic factor | Q48642140 | ||
| A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis | Q48686925 | ||
| Brain-derived neurotrophic factor (BDNF) overexpression in the forebrain results in learning and memory impairments. | Q51944330 | ||
| 7,8-dihydroxyflavone protects PC12 cells against 6-hydroxydopamine-induced cell death through modulating PI3K/Akt and JNK pathways. | Q54328527 | ||
| Cell Survival through Trk Neurotrophin Receptors Is Differentially Regulated by Ubiquitination | Q59783949 | ||
| Neurotrophic factors in Alzheimer's and Parkinson's disease brain | Q64768197 | ||
| Endocytosis of activated TrkA: evidence that nerve growth factor induces formation of signaling endosomes | Q71955066 | ||
| Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity | Q72664326 | ||
| Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches | Q34156542 | ||
| 7,8-dihydroxyflavone exhibits therapeutic efficacy in a mouse model of Rett syndrome | Q34242515 | ||
| 7,8-dihydroxyflavone rescues spatial memory and synaptic plasticity in cognitively impaired aged rats | Q34281150 | ||
| Biochemical and biophysical investigation of the brain-derived neurotrophic factor mimetic 7,8-dihydroxyflavone in the binding and activation of the TrkB receptor | Q34283434 | ||
| Optimization of a small tropomyosin-related kinase B (TrkB) agonist 7,8-dihydroxyflavone active in mouse models of depression | Q34300190 | ||
| Small-molecule TrkB receptor agonists improve motor function and extend survival in a mouse model of Huntington's disease | Q34330172 | ||
| 7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease | Q34370099 | ||
| Small-molecule trkB agonists promote axon regeneration in cut peripheral nerves | Q34371740 | ||
| 7,8-Dihydroxyflavone improves memory consolidation processes in rats and mice | Q34373618 | ||
| Antioxidant action of 7,8-dihydroxyflavone protects PC12 cells against 6-hydroxydopamine-induced cytotoxicity | Q34384473 | ||
| 7,8-dihydroxyflavone ameliorates scopolamine-induced Alzheimer-like pathologic dysfunction | Q34390991 | ||
| 7,8-Dihydroxyflavone improves motor performance and enhances lower motor neuronal survival in a mouse model of amyotrophic lateral sclerosis. | Q34410523 | ||
| BDNF regulates eating behavior and locomotor activity in mice | Q34667950 | ||
| Expansion of the dentate mossy fiber-CA3 projection in the brain-derived neurotrophic factor-enriched mouse hippocampus | Q35073511 | ||
| Activation of muscular TrkB by its small molecular agonist 7,8-dihydroxyflavone sex-dependently regulates energy metabolism in diet-induced obese mice | Q35205542 | ||
| 7,8-dihydroxyflavone, a small-molecule TrkB agonist, reverses memory deficits and BACE1 elevation in a mouse model of Alzheimer's disease | Q35622640 | ||
| Subcutaneously administered apomorphine: pharmacokinetics and metabolism | Q35705678 | ||
| O-methylated metabolite of 7,8-dihydroxyflavone activates TrkB receptor and displays antidepressant activity | Q36691791 | ||
| Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene | Q36700576 | ||
| The Synthesis of Nerve Growth Factor and Brain-Derived Neurotrophic Factor in Hippocampal and Cortical Neurons Is Regulated by Specific Transmitter Systemsa | Q36927722 | ||
| Tandem repeat peptide strategy for the design of neurotrophic factor mimetics. | Q37090155 | ||
| BDNF as a pain modulator | Q37178450 | ||
| Role of exercise-induced brain-derived neurotrophic factor production in the regulation of energy homeostasis in mammals | Q37596188 | ||
| L-Dopa prodrugs: an overview of trends for improving Parkinson's disease treatment. | Q37954725 | ||
| 7,8-Dihydroxyflavone as a pro-neurotrophic treatment for neurodevelopmental disorders. | Q38556634 | ||
| Protective effects of 7,8-dihydroxyflavone on retinal ganglion and RGC-5 cells against excitotoxic and oxidative stress. | Q39262019 | ||
| Novel agonist monoclonal antibodies activate TrkB receptors and demonstrate potent neurotrophic activities. | Q40232259 | ||
| Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signaling | Q40358414 | ||
| The p75 neurotrophin receptor | Q40590902 | ||
| Role of neurotrophins and trk receptors in the development and maintenance of sensory neurons: an overview | Q41055284 | ||
| Neurotrophins and the specification of neuronal phenotype | Q41055322 | ||
| Neurotrophic factors and amyotrophic lateral sclerosis | Q41096229 | ||
| p75 neurotrophin receptor reduces ligand-induced Trk receptor ubiquitination and delays Trk receptor internalization and degradation | Q42127048 | ||
| Vulnerability to depression: from brain neuroplasticity to identification of biomarkers. | Q42494002 | ||
| Activation of Trk neurotrophin receptor signaling by pituitary adenylate cyclase-activating polypeptides | Q43850091 | ||
| Involvement of protein kinase C activation and cell survival/ cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action | Q44023075 | ||
| Animal model of dementia induced by entorhinal synaptic damage and partial restoration of cognitive deficits by BDNF and carnitine | Q44188025 | ||
| (-)Epicatechin stimulates ERK-dependent cyclic AMP response element activity and up-regulates GluR2 in cortical neurons. | Q44245674 | ||
| Transactivation of Trk neurotrophin receptors by G-protein-coupled receptor ligands occurs on intracellular membranes. | Q44999225 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2 | |
| P577 | publication date | 2016-01-01 | |
| P1433 | published in | Translational Neurodegeneration | Q18216027 |
| P1476 | title | 7,8-dihydroxyflavone, a small molecular TrkB agonist, is useful for treating various BDNF-implicated human disorders | |
| P478 | volume | 5 |
| Q38719796 | 7,8-DHF Treatment Induces Cyr61 Expression to Suppress Hypoxia Induced ER Stress in HK-2 Cells. |
| Q37448714 | 7,8-Dihydroxyflavone Ameliorates Cognitive Impairment by Inhibiting Expression of Tau Pathology in ApoE-Knockout Mice. |
| Q46092253 | 7,8-Dihydroxyflavone facilitates the action exercise to restore plasticity and functionality: Implications for early brain trauma recovery |
| Q54983806 | Activation of endothelial TrkB receptors induces relaxation of resistance arteries. |
| Q48024103 | Biosynthesis of novel 7,8-dihydroxyflavone glycoside derivatives and in silico study of their effects on BACE1 inhibition |
| Q37065412 | Cognitive impairments following cranial irradiation can be mitigated by treatment with a tropomyosin receptor kinase B agonist |
| Q61806582 | Depression as a Neuroendocrine Disorder: Emerging Neuropsychopharmacological Approaches beyond Monoamines |
| Q57069297 | Engineering mesenchymal stem cells to improve their exosome efficacy and yield for cell-free therapy |
| Q52607586 | Flavonoid 8-O-Glucuronides from the Aerial Parts of Malva verticillata and Their Recovery Effects on Alloxan-Induced Pancreatic Islets in Zebrafish. |
| Q47655761 | From the Cover: 7,8-Dihydroxyflavone Rescues Lead-Induced Impairment of Vesicular Release: A Novel Therapeutic Approach for Lead Intoxicated Children |
| Q52314492 | Glaucoma pathogenesis and neurotrophins: Focus on the Molecular and Genetic basis for Therapeutic prospects. |
| Q92708909 | HPO-Shuffle: an associated gene prioritization strategy and its application in drug repurposing for the treatment of canine epilepsy |
| Q39419507 | Induction of thermogenic adipocytes: molecular targets and thermogenic small molecules |
| Q47746288 | Intake of 7,8-dihydroxyflavone from pregnancy to weaning prevents cognitive deficits in adult offspring after maternal immune activation. |
| Q26741247 | Neurotrophic factor small-molecule mimetics mediated neuroregeneration and synaptic repair: emerging therapeutic modality for Alzheimer's disease |
| Q48019570 | Neurotrophic function of phytochemicals for neuroprotection in aging and neurodegenerative disorders: modulation of intracellular signaling and gene expression |
| Q47800596 | Prevention of Amyloid-β and Tau Pathologies, Associated Neurodegeneration, and Cognitive Deficit by Early Treatment with a Neurotrophic Compound |
| Q33846559 | Prevention of dendritic and synaptic deficits and cognitive impairment with a neurotrophic compound |
| Q92812717 | Regulation of BDNF-TrkB Signaling and Potential Therapeutic Strategies for Parkinson's Disease |
| Q92449158 | Sex differences in Hippocampal Memory and Learning following Neonatal Brain Injury: Is There a Role for Estrogen Receptor-α? |
| Q57040167 | Synapse-selective rapid potentiation of hippocampal synaptic transmission by 7,8-dihydroxyflavone |
| Q60923268 | The potential of small molecule brain-derived neurotrophic factor: mimetics to treat inherited retinal degeneration |
| Q39157121 | Therapeutic potential of brain-derived neurotrophic factor (BDNF) and a small molecular mimics of BDNF for traumatic brain injury |
| Q92588893 | Timing of Treatment with the Flavonoid 7,8-DHF Critically Impacts on Its Effects on Learning and Memory in the Ts65Dn Mouse |
| Q50421431 | Tyrosine receptor kinase B receptor activation reverses the impairing effects of acute nicotine on contextual fear extinction |
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