| scholarly article | Q13442814 |
| P50 | author | Sheila A Lukehart | Q89741422 |
| Caroline E Cameron | Q61478670 | ||
| P2860 | cites work | Syphilis on the rise in the USA | Q84760422 |
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| Treponema pallidum: doing a remarkable job with what it's got | Q74588620 | ||
| Further attempts to immunize rabbits with killed Treponema pallidum | Q75878755 | ||
| The rate of development and degree of acquired immunity in experimental syphilis | Q79458182 | ||
| The rate of multiplication of Treponema pallidum in normal and immune rabbits | Q80325595 | ||
| The duration of acquired immunity in experimental syphilis | Q80351551 | ||
| 2004 Canadian sexually transmitted infections surveillance report | Q80586945 | ||
| How can we avoid the productivity gap? | Q80961643 | ||
| The re-emergence of syphilis among homosexually active men in Melbourne | Q81347213 | ||
| The value of vaccination | Q82681320 | ||
| Attempted immunization of rabbits against syphilis with killed Treponema pallidum and adjuvants | Q83284213 | ||
| TprC/D (Tp0117/131), a trimeric, pore-forming rare outer membrane protein of Treponema pallidum, has a bipartite domain structure | Q30155363 | ||
| TP0326, a Treponema pallidum β-barrel assembly machinery A (BamA) orthologue and rare outer membrane protein | Q30155589 | ||
| Surface Immunolabeling and Consensus Computational Framework To Identify Candidate Rare Outer Membrane Proteins ofTreponema pallidum | Q30156010 | ||
| Cryo-electron tomography elucidates the molecular architecture of Treponema pallidum, the syphilis spirochete | Q30492095 | ||
| Global estimates of syphilis in pregnancy and associated adverse outcomes: analysis of multinational antenatal surveillance data | Q30596983 | ||
| Treponema pallidum major sheath protein homologue Tpr K is a target of opsonic antibody and the protective immune response. | Q31904771 | ||
| Function and protective capacity of Treponema pallidum subsp. pallidum glycerophosphodiester phosphodiesterase | Q31968473 | ||
| Treponema pallidum invades intercellular junctions of endothelial cell monolayers | Q33575526 | ||
| Cellular architecture of Treponema pallidum: novel flagellum, periplasmic cone, and cell envelope as revealed by cryo electron tomography | Q33695243 | ||
| Bifunctional role of the Treponema pallidum extracellular matrix binding adhesin Tp0751. | Q33768367 | ||
| A monoclonal antibody that conveys in vitro killing and partial protection in experimental syphilis binds a phosphorylcholine surface epitope of Treponema pallidum | Q33769139 | ||
| Outer membrane ultrastructure explains the limited antigenicity of virulent Treponema pallidum | Q33845325 | ||
| The tprK gene is heterogeneous among Treponema pallidum strains and has multiple alleles | Q34003322 | ||
| Defining the interaction of the Treponema pallidum adhesin Tp0751 with laminin | Q34111710 | ||
| Sexually transmitted infections and HIV: epidemiology and interventions | Q34151789 | ||
| Sexually transmitted diseases treatment guidelines, 2010. | Q34155140 | ||
| Host defense mechanisms in secondary syphilitic lesions: a role for IFN-gamma-/IL-17-producing CD8+ T cells? | Q34254490 | ||
| Immunization with the N-terminal portion of Treponema pallidum repeat protein K attenuates syphilitic lesion development in the rabbit model | Q34261750 | ||
| Humoral immunity in experimental syphilis. I. The demonstration of resistance conferred by passive immunization. | Q34313202 | ||
| Biological basis for syphilis | Q34334047 | ||
| Activation and proteolytic activity of the Treponema pallidum metalloprotease, pallilysin | Q34387058 | ||
| Progress towards an effective syphilis vaccine: the past, present and future | Q34490385 | ||
| A novel Treponema pallidum antigen, TP0136, is an outer membrane protein that binds human fibronectin | Q34589271 | ||
| Antigenic variation in Treponema pallidum: TprK sequence diversity accumulates in response to immune pressure during experimental syphilis. | Q34589433 | ||
| Fine analysis of genetic diversity of the tpr gene family among treponemal species, subspecies and strains. | Q34734274 | ||
| The immune response to infection with Treponema pallidum, the stealth pathogen | Q34935201 | ||
| Identification of aTreponema pallidumLaminin-Binding Protein | Q34936498 | ||
| Genetics of motility and chemotaxis of a fascinating group of bacteria: the spirochetes | Q34995434 | ||
| In vitro model of Treponema pallidum invasiveness | Q35099539 | ||
| Antigenic variation of TprK V regions abrogates specific antibody binding in syphilis | Q35217516 | ||
| The infectious origins of stillbirth | Q35550166 | ||
| Syphilis: using modern approaches to understand an old disease | Q35578589 | ||
| Resurgence of early congenital syphilis in Alberta | Q35850414 | ||
| Can population differences explain the contrasting results of the Mwanza, Rakai, and Masaka HIV/sexually transmitted disease intervention trials?: A modeling study | Q35985936 | ||
| Demonstration of rare protein in the outer membrane of Treponema pallidum subsp. pallidum by freeze-fracture analysis | Q36181808 | ||
| Treponema pallidum elicits innate and adaptive cellular immune responses in skin and blood during secondary syphilis: a flow-cytometric analysis | Q36253541 | ||
| An estimate of syphilis incidence in Eastern Europe | Q36358855 | ||
| Biophysical and bioinformatic analyses implicate the Treponema pallidum Tp34 lipoprotein (Tp0971) in transition metal homeostasis | Q36435252 | ||
| Heterologous expression of the Treponema pallidum laminin-binding adhesin Tp0751 in the culturable spirochete Treponema phagedenis | Q36540520 | ||
| Epidemic infectious syphilis in inner Sydney--strengthening enhanced surveillance | Q36701971 | ||
| Prospective, multi-centre clinic-based evaluation of four rapid diagnostic tests for syphilis | Q36928802 | ||
| Treponema pallidum fibronectin-binding proteins | Q37573888 | ||
| Is syphilis resurgent in New Zealand in the 21st century? A case series of infectious syphilis presenting to the Auckland Sexual Health Service. | Q37865251 | ||
| Delivering the promise of the Decade of Vaccines: opportunities and challenges in the development of high quality new vaccines | Q38100040 | ||
| Relative risks and population attributable fraction of incident HIV associated with symptoms of sexually transmitted diseases and treatable symptomatic sexually transmitted diseases in Rakai District, Uganda. Rakai Project Team | Q38886388 | ||
| Syphilis in pregnancy in Tanzania. I. Impact of maternal syphilis on outcome of pregnancy | Q39581532 | ||
| Lesions of primary and secondary syphilis contain activated cytolytic T cells | Q39824504 | ||
| The re-emergence of syphilis in the United Kingdom: the new epidemic phases. | Q40435781 | ||
| Diagnosis and management of syphilis | Q40553315 | ||
| Treponema pallidum and the quest for outer membrane proteins | Q40955271 | ||
| Endemic Syphilis: Passive Transfer of Resistance with Serum and Cells in Hamsters | Q41120268 | ||
| Length of guanosine homopolymeric repeats modulates promoter activity of subfamily II tpr genes of Treponema pallidum ssp. pallidum. | Q41320865 | ||
| The antibody response in rabbits to killed suspensions of pathogenic T. pallidum | Q41818938 | ||
| Immunological evaluation and cellular location analysis of the TprI antigen of Treponema pallidum subsp. pallidum | Q41894916 | ||
| Antigenicity in rabbits and relation to immunity. | Q42035859 | ||
| Quantitation of rabbit cytokine mRNA by real-time RT-PCR. | Q42133169 | ||
| STUDIES IN EXPERIMENTAL SYPHILIS : VI. ON VARIATIONS IN THE RESPONSE OF TREATED RABBITS TO REINOCULATION; AND ON CRYPTOGENETIC REINFECTION WITH SYPHILIS. | Q42135838 | ||
| Gene conversion: a mechanism for generation of heterogeneity in the tprK gene of Treponema pallidum during infection | Q42628964 | ||
| The relationship of treponemal immobilizing antibody to immunity in syphilis. | Q43627112 | ||
| Production of immobilizing antibodies unaccompanied by active immunity to Treponema pallidum as shown by injecting rabbits and mice with the killed organisms. | Q43750489 | ||
| Prospects for development of a treponemal vaccine | Q43850464 | ||
| Treponema pallidum strain-specific differences in neuroinvasion and clinical phenotype in a rabbit model | Q44296865 | ||
| Immunity in experimental syphilis. VI. Successful vaccination of rabbits with Treponema pallidum, Nichols strain, attenuated by -irradiation | Q44952549 | ||
| Subfamily I Treponema pallidum repeat protein family: sequence variation and immunity | Q47317855 | ||
| How the research-based industry approaches vaccine development and establishes priorities. | Q47919360 | ||
| Syphilis and social upheaval in China | Q48820963 | ||
| Syphilis and gonorrhoea in men who have sex with men: a European overview. | Q51601201 | ||
| Penicillin treatment of syphilis: clearing away the shadow on the land. | Q53114769 | ||
| Biology of the treponematoses based on studies carried out at the International Treponematosis Laboratory Center of the Johns Hopkins University under the auspices of the World Health Organization. | Q53458023 | ||
| A subpopulation of Treponema pallidum is resistant to phagocytosis: possible mechanism of persistence | Q54256818 | ||
| Resistance and serological changes in rabbits immunized with virulent Treponema pallidum sonicate. | Q54674992 | ||
| Rapid increase in gonorrhoea and syphilis diagnoses in England in 2011. | Q55056502 | ||
| Macrophage-Mediated Killing of Opsonized Treponema pallidum | Q67718846 | ||
| Experimental congenital syphilis in rabbits | Q69925016 | ||
| Invasion of the central nervous system by Treponema pallidum: implications for diagnosis and treatment | Q70225612 | ||
| The immunoprotective niche— A new pathogenic mechanism for syphilis, the systemic mycoses and other infectious diseases | Q70500177 | ||
| VDRL antibodies enhance phagocytosis of Treponema pallidum by macrophages | Q70696667 | ||
| Characterization of lymphocyte responsiveness in early experimental syphilis. II. Nature of cellular infiltration and Treponema pallidum distribution in testicular lesions | Q72603802 | ||
| P433 | issue | 14 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | vaccine | Q134808 |
| vaccine development | Q27133094 | ||
| P304 | page(s) | 1602-1609 | |
| P577 | publication date | 2013-10-14 | |
| P1433 | published in | Vaccine | Q7907941 |
| P1476 | title | Current status of syphilis vaccine development: need, challenges, prospects | |
| P478 | volume | 32 |
| Q30152961 | A Homology Model Reveals Novel Structural Features and an Immunodominant Surface Loop/Opsonic Target in the Treponema pallidum BamA Ortholog TP_0326 |
| Q30238982 | A double-edged sword: does highly active antiretroviral therapy contribute to syphilis incidence by impairing immunity to Treponema pallidum? |
| Q37690954 | An In Silico Identification of Common Putative Vaccine Candidates against Treponema pallidum: A Reverse Vaccinology and Subtractive Genomics Based Approach. |
| Q64992110 | An Update on the Global Epidemiology of Syphilis. |
| Q34595868 | Antigenic variation of TprK facilitates development of secondary syphilis |
| Q30152965 | Bipartite Topology of Treponema pallidum Repeat Proteins C/D and I: OUTER MEMBRANE INSERTION, TRIMERIZATION, AND PORIN FUNCTION REQUIRE A C-TERMINAL β-BARREL DOMAIN |
| Q37845929 | Current barriers, challenges and opportunities for the development of effective STI vaccines: point of view of vaccine producers, biotech companies and funding agencies |
| Q97545395 | Development of vaccines against the sexually transmitted infections gonorrhoea, syphilis, Chlamydia, herpes simplex virus, human immunodeficiency virus and Zika virus |
| Q37367102 | Epidemiological impact of a syphilis vaccine: a simulation study. |
| Q92641849 | Evaluation of the Protective Ability of the Treponema pallidum subsp. pallidum Tp0126 OmpW Homolog in the Rabbit Model of Syphilis |
| Q37665012 | Future prospects for new vaccines against sexually transmitted infections |
| Q29994751 | Identification of Tp0751 (Pallilysin) as a Treponema pallidum Vascular Adhesin by Heterologous Expression in the Lyme disease Spirochete. |
| Q35980127 | Investments in sexually transmitted infection research, 1997-2013: a systematic analysis of funding awarded to UK institutions |
| Q58004751 | Molecular characterization of Treponema pallidum subsp. pallidum in Switzerland and France with a new multilocus sequence typing scheme |
| Q92487923 | Prevalence of Syphilis among Pregnant Women in Sub-Saharan Africa: A Systematic Review and Meta-Analysis |
| Q40606107 | Return of the Great Pox. |
| Q39201552 | Risk factors for syphilis in women: case-control study. |
| Q55339367 | Sequence Variation of Rare Outer Membrane Protein β-Barrel Domains in Clinical Strains Provides Insights into the Evolution of Treponema pallidum subsp. pallidum, the Syphilis Spirochete. |
| Q61804866 | Seroprevalence of syphilis and its risk factors among pregnant women attending antenatal care at Felege Hiwot Referral Hospital, Bahir Dar, northwest Ethiopia: a cross-sectional study |
| Q58105411 | Surveillance of Maternal Syphilis in China: Pregnancy Outcomes and Determinants of Congenital Syphilis |
| Q64123939 | Syphilis |
| Q30235033 | Syphilis: Re-emergence of an old foe. |
| Q38263977 | Syphilis: antibiotic treatment and resistance |
| Q92559431 | The pan-genome of Treponema pallidum reveals differences in genome plasticity between subspecies related to venereal and non-venereal syphilis |
| Q55250836 | The wide utility of rabbits as models of human diseases. |
| Q37844836 | Toward global prevention of sexually transmitted infections (STIs): the need for STI vaccines. |
| Q35609362 | Transcription of TP0126, Treponema pallidum putative OmpW homolog, is regulated by the length of a homopolymeric guanosine repeat |
| Q38976715 | Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen |
| Q42230455 | Vaccines against sexually transmitted infections: the way forward |
| Q49067044 | Vaccines for sexually transmitted infections: past, present and future |
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