Disease Biomarkers in Multiple Sclerosis

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Disease Biomarkers in Multiple Sclerosis is …
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review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1035364722
P356DOI10.1007/BF03256329
P8608Fatcat IDrelease_4ln5d2pzljccbnszn2dn5vf2ly
P3181OpenCitations bibliographic resource ID3566601
P698PubMed publication ID19712003

P2093author name stringSaud A. Sadiq
Violaine K. Harris
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Cleavage of cystatin C is not associated with multiple sclerosisQ28265824
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Imaging neuronal and axonal degeneration in multiple sclerosisQ30885236
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Whole-brain N-acetylaspartate as a surrogate marker of neuronal damage in diffuse neurologic disorders.Q31132463
Cleavage of cystatin C in the cerebrospinal fluid of patients with multiple sclerosisQ33232505
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Alteration of cystatin C in the cerebrospinal fluid of multiple sclerosisQ33256695
Cerebrospinal fluid proteome profile in multiple sclerosisQ33299647
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Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets.Q33319975
N-acetylaspartic acid in cerebrospinal fluid of multiple sclerosis patients determined by gas-chromatography-mass spectrometryQ33556095
Activation of the inducible form of nitric oxide synthase in the brains of patients with multiple sclerosisQ33642743
Inducible nitric oxide synthase and nitrotyrosine are found in monocytes/macrophages and/or astrocytes in acute, but not in chronic, multiple sclerosis.Q33997314
Nitric oxide and blood-brain barrier integrityQ34276274
Antibodies to native myelin oligodendrocyte glycoprotein are serologic markers of early inflammation in multiple sclerosis.Q34479121
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Blocking effects of serum reactive antibodies induced by glatiramer acetate treatment in multiple sclerosisQ44560635
Increased 14-3-3 immunoreactivity in glial elements in patients with multiple sclerosisQ44647503
Antibodies to glatiramer acetate do not interfere with its biological functions and therapeutic efficacyQ44685789
Antibodies against Epstein-Barr virus and herpesvirus type 6 are associated with the early phases of multiple sclerosisQ44866997
Plasma osteopontin levels in multiple sclerosis.Q45180843
Cerebrospinal fluid myelin basic protein immunoreactivity as an indicator of brain damage in childrenQ45261040
Reduced cerebrospinal fluid BACE1 activity in multiple sclerosisQ46157365
Interferon beta 1-b in verbal memory functioning of patients with relapsing-remitting multiple sclerosisQ46200872
Identification of autoantibodies associated with myelin damage in multiple sclerosisQ46424597
A randomized clinical trial of valacyclovir in multiple sclerosisQ46548027
Soluble Nogo-A in CSF is not a useful biomarker for multiple sclerosisQ46582323
Increased CSF-BACE 1 activity is associated with ApoE-epsilon 4 genotype in subjects with mild cognitive impairment and Alzheimer's diseaseQ46707483
Axonal injury in early multiple sclerosis is irreversible and independent of the short-term disease evolutionQ46814966
Protective and therapeutic role for alphaB-crystallin in autoimmune demyelinationQ46968199
No major association of ApoE genotype with disease characteristics and MRI findings in multiple sclerosisQ47276347
Association of apolipoprotein E and myeloperoxidase genotypes to clinical course of familial and sporadic multiple sclerosisQ47276359
Proteomic analysis of cerebrospinal fluid from multiple sclerosis patientsQ47279465
Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis.Q47357498
Tau protein in cerebrospinal fluid: a possible marker of poor outcome in patients with early relapsing-remitting multiple sclerosis.Q47442661
MxA Gene Expression Analysis as an Interferon-β Bioactivity Measurement in Patients with Multiple Sclerosis and the Identification of Antibody-Mediated Decreased BioactivityQ47583383
Influence of apolipoprotein E epsilon4 genotype on brain tissue integrity in relapsing-remitting multiple sclerosisQ47735680
Tau protein and 14-3-3 are elevated in the cerebrospinal fluid of patients with multiple sclerosis and correlate with intrathecal synthesis of IgG.Q47767870
Accelerated evolution of brain atrophy and "black holes" in MS patients with APOE-epsilon 4.Q47866571
Nitric oxide as an activity marker in multiple sclerosisQ47926902
Neutralizing antibodies against IFN-beta in multiple sclerosis: antagonization of IFN-beta mediated suppression of MMPs.Q48149612
Serial proton magnetic resonance spectroscopy in acute multiple sclerosis lesionsQ48182289
APOE epsilon 4 allele is associated with cognitive impairment in patients with multiple sclerosisQ48187897
Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology.Q48200750
Subpial demyelination in the cerebral cortex of multiple sclerosis patientsQ48233815
Antimyelin antibodies with no progression to multiple sclerosis.Q48298505
Lack of association between antimyelin antibodies and progression to multiple sclerosisQ48298518
The significance of brain magnetic resonance imaging abnormalities at presentation with clinically isolated syndromes suggestive of multiple sclerosis. A 5-year follow-up studyQ48335809
Tetranectin in cerebrospinal fluid of patients with multiple sclerosis.Q48371726
Increased release of interleukin-12p40 in MS: association with intracerebral inflammationQ48390502
Multiple sclerosis: Neurofilament light chain antibodies are correlated to cerebral atrophyQ48400490
Axonal damage correlates with disability in patients with relapsing-remitting multiple sclerosis. Results of a longitudinal magnetic resonance spectroscopy studyQ48408024
Lumbar cerebrospinal fluid proteome in multiple sclerosis: characterization by ultrafiltration, liquid chromatography, and mass spectrometryQ48477701
Cerebrospinal fluid and serum nitric oxide metabolites in patients with multiple sclerosisQ48494263
A new focal EAE model of cortical demyelination: multiple sclerosis-like lesions with rapid resolution of inflammation and extensive remyelinationQ48530177
Patients with progressive multiple sclerosis have elevated antibodies to neurofilament subunitQ48605590
Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitmentQ48701331
Cortical demyelination and diffuse white matter injury in multiple sclerosis.Q48726181
Immunocytochemical characterization of the expression of inducible and constitutive isoforms of nitric oxide synthase in demyelinating multiple sclerosis lesionsQ48822577
The CSF levels of total-tau and phosphotau in patients with relapsing-remitting multiple sclerosisQ48823169
Tau protein level in cerebrospinal fluid is increased in patients with early multiple sclerosis.Q48853343
Up-regulation of osteopontin and alphaBeta-crystallin in the normal-appearing white matter of multiple sclerosis: an immunohistochemical study utilizing tissue microarraysQ48892536
Neuronal damage in autoimmune neuroinflammation mediated by the death ligand TRAIL.Q48894792
Demyelination induced in aggregating brain cell cultures by a monoclonal antibody against myelin/oligodendrocyte glycoproteinQ48931070
IL-6 and CCL2 levels in CSF are associated with the clinical course of MS: implications for their possible immunopathogenic rolesQ48934460
Cerebrospinal fluid myelin basic protein as a prognostic marker in patients with head injuryQ49305384
Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis.Q51027456
Transplantation of human neural stem cells for spinal cord injury in primates.Q51527726
Antimyelin antibodies in clinically isolated syndromes correlate with inflammation in MRI and CSF.Q51763866
Proteomic analysis of human cerebral endothelial cells activated by multiple sclerosis serum and IFNbeta-1b.Q52582180
Strong EBV-specific CD8+ T-cell response in patients with early multiple sclerosis.Q53471810
The importance of measuring IFNbeta bioactivity: monitoring in MS patients and the effect of anti-IFNbeta antibodies.Q53851476
Biological responsiveness to first injections of interferon-beta in patients with multiple sclerosis.Q53877418
CSF and serum levels of soluble interleukin-6 receptors (sIL-6R and sgp130), but not of interleukin-6 are altered in multiple sclerosis.Q54077161
Expression and regulation of IFNalpha/beta receptor in IFNbeta-treated patients with multiple sclerosis.Q54509774
Interferon receptor expression in multiple sclerosis patients.Q54565439
Dynamics of interferon-beta modulated mRNA biomarkers in multiple sclerosis patients with anti-interferon-beta neutralizing antibodies.Q54601819
Persistent neutralizing antibodies abolish the interferon beta bioavailability in MS patients.Q54788025
Gender-related effect of clinical and genetic variables on the cognitive impairment in multiple sclerosis.Q55039401
CSF 14-3-3 protein assay and MRI as prognostic markers in patients with a clinically isolated syndrome suggestive of MSQ57602005
High CSF neurofilament heavy chain levels in neuromyelitis opticaQ57725968
Randomised double-blind placebo-controlled study of interferon β-1a in relapsing/remitting multiple sclerosisQ57912405
Myelin oligodendrocyte glycoprotein antibodies in pathologically proven multiple sclerosis: frequency, stability and clinicopathologic correlationsQ59273833
Biological markers of interferon-beta therapy: comparison among interferon-stimulated genes MxA, TRAIL and XAF-1.Q34491595
Regulation of interferon receptor expression in human blood lymphocytes in vitro and during interferon therapyQ34578618
Extensive cortical remyelination in patients with chronic multiple sclerosis.Q34612670
Anti-myelin antibodies predict the clinical outcome after a first episode suggestive of MS.Q34653997
Myelin oligodendrocyte glycoprotein antibodies and multiple sclerosis in healthy young adults.Q34657019
The incidence and significance of anti-natalizumab antibodies: results from AFFIRM and SENTINEL.Q34673142
Multiple sclerosis: an immune or neurodegenerative disorder?Q34786872
The 14-3-3 protein epsilon isoform expressed in reactive astrocytes in demyelinating lesions of multiple sclerosis binds to vimentin and glial fibrillary acidic protein in cultured human astrocytesQ35103017
The role of nitric oxide in multiple sclerosisQ35172450
Expression of chemokines in the CSF and correlation with clinical disease activity in patients with multiple sclerosis.Q35466511
Anti-IFN BAb and NAb antibodies: a minireviewQ35580806
Identification of molecular biomarkers for multiple sclerosisQ35789583
Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoproteinQ35818687
Antimyelin antibodies and the risk of relapse in patients with a primary demyelinating eventQ36142086
Multiple sclerosis: advances in understanding, diagnosing, and treating the underlying disease.Q36381085
The value of animal models for drug development in multiple sclerosis.Q36458937
Epidemiology and natural history of multiple sclerosis: new insightsQ36479921
The role of TRAIL/TRAIL receptors in central nervous system pathologyQ36813631
Abrogation of T cell quiescence characterizes patients at high risk for multiple sclerosis after the initial neurological eventQ36824348
Cerebrospinal fluid markers in Creutzfeldt-Jakob diseaseQ36865663
A prospective study on the predictive value of CSF oligoclonal bands and MRI in acute isolated neurological syndromes for subsequent progression to multiple sclerosisQ36891696
Amyloid beta protein and tau in cerebrospinal fluid and plasma as biomarkers for dementia: a review of recent literatureQ37242816
Soluble IL-2RA levels in multiple sclerosis subjects and the effect of soluble IL-2RA on immune responsesQ37712459
Cerebrospinal fluid levels of brain specific proteins in optic neuritisQ38339554
Neuropsychologic status in multiple sclerosis after treatment with glatiramerQ38450118
Cerebrospinal Fluid Myelin Basic Protein and Multiple SclerosisQ39509340
TRAIL, CXCL10 and CCL2 plasma levels during long-term Interferon-beta treatment of patients with multiple sclerosis correlate with flu-like adverse effects but do not predict therapeutic response.Q40172029
TNF-related apoptosis inducing ligand (TRAIL) as a potential response marker for interferon-beta treatment in multiple sclerosisQ40580264
Death ligand TRAIL induces no apoptosis but inhibits activation of human (auto)antigen-specific T cellsQ40733996
Neurofilament protein in cerebrospinal fluid: a potential marker of activity in multiple sclerosis.Q40864697
Apolipoprotein E alleles as risk factors in Alzheimer's diseaseQ41036434
Interleukin-6 is elevated in plasma in multiple sclerosisQ41177826
High prevalence of anti-alpha-crystallin antibodies in multiple sclerosis: correlation with severity and activity of diseaseQ41689185
Humoral and cellular immune responses to Copolymer 1 in multiple sclerosis patients treated with CopaxoneQ43562148
14-3-3 protein in the CSF as prognostic marker in early multiple sclerosisQ43721324
N-acetylaspartate is an axon-specific marker of mature white matter in vivo: a biochemical and immunohistochemical study on the rat optic nerveQ43849057
Evaluation of bioavailability of three types of IFNbeta in multiple sclerosis patients by a new quantitative-competitive-PCR method for MxA quantification.Q43874500
MR correlates of cerebral atrophy in patients with multiple sclerosis.Q44114075
Elevated osteopontin levels in active relapsing-remitting multiple sclerosisQ44140769
Relapsing-remitting multiple sclerosis and whole-brain N-acetylaspartate measurement: evidence for different clinical cohorts initial observationsQ44159266
Nitric oxide synthase is present in the cerebrospinal fluid of patients with active multiple sclerosis and is associated with increases in cerebrospinal fluid protein nitrotyrosine and S-nitrosothiols and with changes in glutathione levelsQ44197130
Anti-myelin antibodies do not allow earlier diagnosis of multiple sclerosisQ59273850
Bioavailability of interferon beta 1b in MS patients with and without neutralizing antibodiesQ59273881
Tau protein seems not to be a useful routine clinical marker of axonal damage in multiple sclerosisQ60169773
A monoclonal antibody against a myelin oligodendrocyte glycoprotein induces relapses and demyelination in central nervous system autoimmune diseaseQ68834759
Cell-mediated immunity to myelin-associated glycoprotein, proteolipid protein, and myelin basic protein in multiple sclerosisQ68974225
Cytokine levels in the cerebrospinal fluid and serum of patients with multiple sclerosisQ70114371
Simultaneous measurement of 2':3' cyclic-nucleotide 3' phosphodiesterase and RNase activities in sera and spinal fluids of multiple sclerosis patientsQ70176298
Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brainsQ71659583
The adhesion molecule and cytokine profile of multiple sclerosis lesionsQ71688111
Cytokine mRNA expression in inflammatory multiple sclerosis lesions: detection by non-radioactive in situ hybridizationQ72427037
Nitric oxide metabolites in CSF of patients with MS are related to clinical disease courseQ73187442
Interleukin-12 and tumor necrosis factor-alpha levels in cerebrospinal fluid of multiple sclerosis patientsQ73230710
Neurological disability correlates with spinal cord axonal loss and reduced N-acetyl aspartate in chronic multiple sclerosis patientsQ73298573
In vitro expression of N-acetyl aspartate by oligodendrocytes: implications for proton magnetic resonance spectroscopy signal in vivoQ73315910
Amyloid beta 1-42 and tau in cerebrospinal fluid after severe traumatic brain injuryQ73385164
Anti-alpha B-crystallin immunoreactivity in inflammatory nervous system diseasesQ73493900
Increased cerebrospinal fluid tau protein in multiple sclerosisQ73828468
Antibodies to myelin basic protein, myelin oligodendrocytes peptides, alpha-beta-crystallin, lymphocyte activation and cytokine production in patients with multiple sclerosisQ73943317
Changes in nitrite and nitrate (NO2-/NO3-) levels in cerebrospinal fluid of patients with multiple sclerosisQ74142796
IL-6 and sIL-6R concentration in the cerebrospinal fluid and serum of MS patientsQ74460100
Neurofilament light protein and glial fibrillary acidic protein as biological markers in MSQ75205821
Heightened intrathecal release of axonal cytoskeletal proteins in multiple sclerosis is associated with progressive disease and clinical disabilityQ77451316
Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis. PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study GroupQ77573170
Increased intrathecal nitric oxide formation in multiple sclerosis; cerebrospinal fluid nitrite as activity markerQ78158199
Cerebrospinal fluid and serum protein levels of tumour necrosis factor-alpha (TNF-alpha) interleukin-6 (IL-6) and soluble interleukin-6 receptor (sIL-6R gp80) in multiple sclerosis patientsQ78555305
Tau protein concentrations in cerebrospinal fluid of patients with multiple sclerosisQ78596324
The measurement of antibodies binding to IFNβ in MS patients treated with IFNβQ79279426
Soluble Nogo-A, an inhibitor of axonal regeneration, as a biomarker for multiple sclerosisQ79622636
Detection of anti-Nogo receptor autoantibody in the serum of multiple sclerosis and controlsQ79763166
APOE genotypes in Greek multiple sclerosis patients: no effect on the MS Severity ScoreQ79898157
Nogo-A is a reliable oligodendroglial marker in adult human and mouse CNS and in demyelinated lesionsQ79932421
Acute transverse myelitis with normal brain MRI : long-term risk of MSQ80201378
Cerebrospinal fluid total tau protein levels in patients with multiple sclerosisQ80298286
Elevated intrathecal antibodies against the medium neurofilament subunit in multiple sclerosisQ80347950
Soluble interleukin-6 receptor (sIL-6R) in cerebrospinal fluid of patients with inflammatory and non inflammatory neurological diseasesQ80382472
Osteopontin levels and increased disease activity in relapsing-remitting multiple sclerosis patientsQ80516387
Specificity and correlation with disease activity of cerebrospinal fluid osteopontin levels in patients with multiple sclerosisQ80682046
Old suspects found guilty--the first genome profile of multiple sclerosisQ80693902
Predictive markers for response to interferon therapy in patients with multiple sclerosisQ80695185
Antibodies against light neurofilaments in multiple sclerosis patientsQ80697259
The 14-3-3 protein in multiple sclerosis: a marker of disease severityQ80835968
Correlations between IL-4, IL-12 levels and CCL2, CCL5 levels in serum and cerebrospinal fluid of multiple sclerosis patientsQ80853050
CSF nitric oxide metabolites are associated with activity and progression of multiple sclerosisQ80908158
Neurofilament and glial fibrillary acidic protein in multiple sclerosisQ80980689
Expression pattern of NOGO-A protein in the human nervous systemQ81192764
Evidence for human herpesvirus 6 variant A antibodies in multiple sclerosis: diagnostic and therapeutic implicationsQ81236151
Identification of interferon-beta antibodies in a reference laboratory setting: findings for 1144 consecutive seraQ81339980
P433issue4
P921main subjectbiomarkerQ864574
multiple sclerosisQ8277
P304page(s)225-244
P577publication date2009-08-01
P1433published inMolecular Diagnosis and TherapyQ15758832
P1476titleDisease Biomarkers in Multiple Sclerosis
P478volume13

Reverse relations

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