BAR: An apoptosis regulator at the intersection of caspases and Bcl-2 family proteins

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BAR: An apoptosis regulator at the intersection of caspases and Bcl-2 family proteins is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2000PNAS...97.2597Z
P356DOI10.1073/PNAS.97.6.2597
P932PMC publication ID15974
P698PubMed publication ID10716992
P5875ResearchGate publication ID12598869

P50authorAdam GodzikQ28028607
P2093author name stringQ Xu
H Zhang
J C Reed
K Pawlowski
Z Xie
S Krajewski
M Krajewska
S Fuess
S Kitada
P2860cites workBax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondriaQ22008484
A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domainQ24306835
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosisQ24307362
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascadeQ24311006
Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeastQ24314476
Inhibition of death receptor signals by cellular FLIPQ24316446
p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulumQ24318875
Bcl-2 targets the protein kinase Raf-1 to mitochondriaQ24321753
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3Q24324482
Gapped BLAST and PSI-BLAST: a new generation of protein database search programsQ24545170
Siah-1 N-terminal RING domain is required for proteolysis function, and C-terminal sequences regulate oligomerization and binding to target proteinsQ24554569
NMR structure and mutagenesis of the FADD (Mort1) death-effector domainQ27757254
Oligomeric structure of the human EphB2 receptor SAM domainQ27766879
Regulation of p53 stability by Mdm2Q27860744
Comparative protein modelling by satisfaction of spatial restraintsQ27860866
Death receptors: signaling and modulationQ28280897
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complexQ28283294
Apoptosis by death factorQ28304002
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligaseQ28506124
Bax directly induces release of cytochrome c from isolated mitochondriaQ28588847
Mitochondria and apoptosisQ29547905
PHD: predicting one-dimensional protein structure by profile-based neural networksQ29614390
The Bcl-2 protein family: arbiters of cell survivalQ29618158
Two CD95 (APO-1/Fas) signaling pathwaysQ29619631
Bcl-2 family proteins as ion-channelsQ33592271
Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosisQ35990527
A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody injectionQ36365792
Structure-function comparisons of the proapoptotic protein Bax in yeast and mammalian cellsQ36563824
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptorsQ36852093
Secondary structure prediction using segment similarityQ40868252
Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL.Q40980272
Bcl-xL functions downstream of caspase-8 to inhibit Fas- and tumor necrosis factor receptor 1-induced apoptosis of MCF7 breast carcinoma cellsQ41057711
Bcl-xL acts downstream of caspase-8 activation by the CD95 death-inducing signaling complex.Q41062034
A role for Jun-N-terminal kinase in anoikis; suppression by bcl-2 and crmA.Q41149112
Bcl-2 inhibits T-cell-mediated cytolysis of a leukemia cell line.Q41442076
Cell death induction by receptors of the TNF family: towards a molecular understanding.Q41554119
Caspases: intracellular signaling by proteolysisQ41656258
Comparison of sequence profiles. Strategies for structural predictions using sequence informationQ41724734
Fold prediction by a hierarchy of sequence, threading, and modeling methodsQ41991659
Immunohistochemical analysis of in vivo patterns of Bcl-X expressionQ42491717
Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c.Q46355494
Bcl–2 protects from lethal hepatic apoptosis induced by an ant–Fas antibody in miceQ64018952
Epitope Mapping by Label-Free Biomolecular Interaction AnalysisQ71544811
Release of cytochrome c and decrease of cytochrome c oxidase in Bax-expressing yeast cells, and prevention of these effects by coexpression of Bcl-xLQ73775219
Inhibition of fas death signals by FLIPsQ77485563
Does the Caenorhabditis elegans protein CED-4 contain a region of homology to the mammalian death effector domain?Q79158419
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
caspase bindingQ21107942
Bifunctional apoptosis regulatorQ21130037
P304page(s)2597-602
P577publication date2000-03-14
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleBAR: An apoptosis regulator at the intersection of caspases and Bcl-2 family proteins
P478volume97