Wikidata entity: Q2335493
| P682 | biological process | ... | Q828130 (signal transduction) | signal transduction |
| P682 | biological process | ... | Q1612119 (immune response) | immune response |
| P682 | biological process | ... | Q428253 (innate immune response) | innate immune response |
| P682 | biological process | ... | Q3346925 (necroptosis) | necroptosis |
| P682 | biological process | ... | Q12021553 (T-helper 1 type immune response) | T-helper 1 type immune response |
| P682 | biological process | ... | Q14330834 (response to lipopolysaccharide) | response to lipopolysaccharide |
| P682 | biological process | ... | Q14633893 (positive regulation of gene expression) | positive regulation of gene expression |
| P682 | biological process | ... | Q14758937 (positive regulation of nitric oxide biosynthetic process) | positive regulation of nitric oxide biosynthetic process |
| P682 | biological process | ... | Q14761969 (positive regulation of NF-kappaB transcription factor activity) | positive regulation of NF-kappaB transcription factor activity |
| P682 | biological process | ... | Q14818068 (positive regulation of transcription by RNA polymerase II) | positive regulation of transcription by RNA polymerase II |
| P682 | biological process | ... | Q14819790 (negative regulation of tumor necrosis factor production) | negative regulation of tumor necrosis factor production |
| P682 | biological process | ... | Q14819849 (inflammatory response) | inflammatory response |
| P682 | biological process | ... | Q14820938 (defense response to bacterium) | defense response to bacterium |
| P682 | biological process | ... | Q14821388 (positive regulation of ERK1 and ERK2 cascade) | positive regulation of ERK1 and ERK2 cascade |
| P682 | biological process | ... | Q14859639 (positive regulation of inflammatory response) | positive regulation of inflammatory response |
| P682 | biological process | ... | Q14859645 (cellular response to mechanical stimulus) | cellular response to mechanical stimulus |
| P682 | biological process | ... | Q14860511 (positive regulation of interleukin-8 production) | positive regulation of interleukin-8 production |
| P682 | biological process | ... | Q14860514 (negative regulation of osteoclast differentiation) | negative regulation of osteoclast differentiation |
| P682 | biological process | ... | Q14860518 (regulation of inflammatory response) | regulation of inflammatory response |
| P682 | biological process | ... | Q14863111 (cellular response to lipopolysaccharide) | cellular response to lipopolysaccharide |
| P682 | biological process | ... | Q14863401 (positive regulation of B cell proliferation) | positive regulation of B cell proliferation |
| P682 | biological process | ... | Q14863711 (negative regulation of ERK1 and ERK2 cascade) | negative regulation of ERK1 and ERK2 cascade |
| P682 | biological process | ... | Q14864035 (positive regulation of I-kappaB kinase/NF-kappaB signaling) | positive regulation of I-kappaB kinase/NF-kappaB signaling |
| P682 | biological process | ... | Q14864136 (positive regulation of stress-activated MAPK cascade) | positive regulation of stress-activated MAPK cascade |
| P682 | biological process | ... | Q14864447 (negative regulation of interferon-gamma production) | negative regulation of interferon-gamma production |
| P682 | biological process | ... | Q14864450 (negative regulation of interleukin-6 production) | negative regulation of interleukin-6 production |
| P682 | biological process | ... | Q14864458 (positive regulation of MHC class II biosynthetic process) | positive regulation of MHC class II biosynthetic process |
| P682 | biological process | ... | Q14864505 (positive regulation of interferon-gamma production) | positive regulation of interferon-gamma production |
| P682 | biological process | ... | Q14864542 (toll-like receptor signaling pathway) | toll-like receptor signaling pathway |
| P682 | biological process | ... | Q14864543 (MyD88-dependent toll-like receptor signaling pathway) | MyD88-dependent toll-like receptor signaling pathway |
| P682 | biological process | ... | Q14864550 (positive regulation of interleukin-12 production) | positive regulation of interleukin-12 production |
| P682 | biological process | ... | Q14864551 (positive regulation of interleukin-6 production) | positive regulation of interleukin-6 production |
| P682 | biological process | ... | Q14864552 (positive regulation of tumor necrosis factor production) | positive regulation of tumor necrosis factor production |
| P682 | biological process | ... | Q14864554 (toll-like receptor 4 signaling pathway) | toll-like receptor 4 signaling pathway |
| P682 | biological process | ... | Q14864567 (positive regulation of macrophage cytokine production) | positive regulation of macrophage cytokine production |
| P682 | biological process | ... | Q14864569 (cellular response to lipoteichoic acid) | cellular response to lipoteichoic acid |
| P682 | biological process | ... | Q14864861 (astrocyte development) | astrocyte development |
| P682 | biological process | ... | Q14864910 (activation of innate immune response) | activation of innate immune response |
| P682 | biological process | ... | Q14864950 (positive regulation of JNK cascade) | positive regulation of JNK cascade |
| P682 | biological process | ... | Q14864986 (positive regulation of interferon-alpha production) | positive regulation of interferon-alpha production |
| P682 | biological process | ... | Q14864987 (positive regulation of interleukin-10 production) | positive regulation of interleukin-10 production |
| P682 | biological process | ... | Q14865219 (positive regulation of chemokine production) | positive regulation of chemokine production |
| P682 | biological process | ... | Q14865229 (defense response to Gram-negative bacterium) | defense response to Gram-negative bacterium |
| P682 | biological process | ... | Q14865489 (macrophage activation) | macrophage activation |
| P682 | biological process | ... | Q14866112 (apoptotic signaling pathway) | apoptotic signaling pathway |
| P682 | biological process | ... | Q14866206 (MyD88-independent toll-like receptor signaling pathway) | MyD88-independent toll-like receptor signaling pathway |
| P682 | biological process | ... | Q14866208 (I-kappaB phosphorylation) | I-kappaB phosphorylation |
| P682 | biological process | ... | Q14866212 (positive regulation of interferon-beta production) | positive regulation of interferon-beta production |
| P682 | biological process | ... | Q14866218 (TRIF-dependent toll-like receptor signaling pathway) | TRIF-dependent toll-like receptor signaling pathway |
| P682 | biological process | ... | Q14876566 (positive regulation of nitric-oxide synthase biosynthetic process) | positive regulation of nitric-oxide synthase biosynthetic process |
| P682 | biological process | ... | Q14881070 (positive regulation of platelet activation) | positive regulation of platelet activation |
| P682 | biological process | ... | Q14881238 (negative regulation of interleukin-17 production) | negative regulation of interleukin-17 production |
| P682 | biological process | ... | Q14885612 (response to bacterium) | response to bacterium |
| P682 | biological process | ... | Q14885627 (lipopolysaccharide-mediated signaling pathway) | lipopolysaccharide-mediated signaling pathway |
| P682 | biological process | ... | Q14905920 (positive regulation of lymphocyte proliferation) | positive regulation of lymphocyte proliferation |
| P682 | biological process | ... | Q14914088 (B cell proliferation involved in immune response) | B cell proliferation involved in immune response |
| P682 | biological process | ... | Q14914089 (nitric oxide production involved in inflammatory response) | nitric oxide production involved in inflammatory response |
| P682 | biological process | ... | Q14914090 (detection of fungus) | detection of fungus |
| P682 | biological process | ... | Q14914091 (detection of lipopolysaccharide) | detection of lipopolysaccharide |
| P682 | biological process | ... | Q14914092 (negative regulation of interleukin-23 production) | negative regulation of interleukin-23 production |
| P682 | biological process | ... | Q14914093 (positive regulation of interleukin-1 production) | positive regulation of interleukin-1 production |
| P682 | biological process | ... | Q14914095 (intestinal epithelial structure maintenance) | intestinal epithelial structure maintenance |
| P682 | biological process | ... | Q14914096 (positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway) | positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway |
| P682 | biological process | ... | Q14914097 (positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway) | positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway |
| P682 | biological process | ... | Q14916317 (immune system process) | immune system process |
| P682 | biological process | ... | Q21095171 (I-kappaB kinase/NF-kappaB signaling) | I-kappaB kinase/NF-kappaB signaling |
| P682 | biological process | ... | Q21114592 (positive regulation of NLRP3 inflammasome complex assembly) | positive regulation of NLRP3 inflammasome complex assembly |
| P682 | biological process | ... | Q21173242 (regulation of dendritic cell cytokine production) | regulation of dendritic cell cytokine production |
| P682 | biological process | ... | Q22303764 (negative regulation of MyD88-independent toll-like receptor signaling pathway) | negative regulation of MyD88-independent toll-like receptor signaling pathway |
| P681 | cell component | ... | Q29548 (plasma membrane) | plasma membrane |
| P681 | cell component | ... | Q79899 (cytoplasm) | cytoplasm |
| P681 | cell component | ... | Q189094 (cell surface) | cell surface |
| P681 | cell component | ... | Q14327652 (integral component of membrane) | integral component of membrane |
| P681 | cell component | ... | Q14330632 (perinuclear region of cytoplasm) | perinuclear region of cytoplasm |
| P681 | cell component | ... | Q14349455 (membrane) | membrane |
| P681 | cell component | ... | Q14633850 (external side of plasma membrane) | external side of plasma membrane |
| P681 | cell component | ... | Q14859540 (integral component of plasma membrane) | integral component of plasma membrane |
| P681 | cell component | ... | Q14860543 (endosome membrane) | endosome membrane |
| P681 | cell component | ... | Q14864978 (lipopolysaccharide receptor complex) | lipopolysaccharide receptor complex |
| P681 | cell component | ... | Q21095104 (intrinsic component of plasma membrane) | intrinsic component of plasma membrane |
| P702 | encoded by | ... | Q14914098 (TLR4) | TLR4 |
| P703 | found in taxon | ... | Q15978631 (Homo sapiens) | Homo sapiens |
| P527 | has part(s) | ... | Q24739837 (Leucine-rich repeat) | Leucine-rich repeat |
| P527 | has part(s) | ... | Q24780090 (Toll/interleukin-1 receptor homology (TIR) domain) | Toll/interleukin-1 receptor homology (TIR) domain |
| P527 | has part(s) | ... | Q24782645 (cysteine-rich flanking region, C-terminal) | cysteine-rich flanking region, C-terminal |
| P527 | has part(s) | ... | Q24783125 (leucine-rich repeat, typical subtype) | leucine-rich repeat, typical subtype |
| P31 | instance of | ... | Q8054 (protein) | protein |
| P680 | molecular function | ... | Q167149 (protein binding) | protein binding |
| P680 | molecular function | ... | Q14864356 (transmembrane signaling receptor activity) | transmembrane signaling receptor activity |
| P680 | molecular function | ... | Q14864979 (lipopolysaccharide binding) | lipopolysaccharide binding |
| P680 | molecular function | ... | Q14907423 (lipopolysaccharide immune receptor activity) | lipopolysaccharide immune receptor activity |
| P361 | part of | ... | Q935326 (Leucine-rich repeat, protein family) | Leucine-rich repeat, protein family |
| P361 | part of | ... | Q24781235 (Leucine-rich repeat domain superfamily) | Leucine-rich repeat domain superfamily |
| P361 | part of | ... | Q41797047 (Toll/interleukin-1 receptor homology (TIR) domain superfamily) | Toll/interleukin-1 receptor homology (TIR) domain superfamily |
| P361 | part of | ... | Q69997199 (NEAT-domain containing methaemoglobin heme sequestration family) | NEAT-domain containing methaemoglobin heme sequestration family |
| P361 | part of | ... | Q83147204 (Toll/interleukin-1 receptor homology (TIR) domain, protein family) | Toll/interleukin-1 receptor homology (TIR) domain, protein family |
| P361 | part of | ... | Q83163261 (Cysteine-rich flanking region, C-terminal domain, protein family) | Cysteine-rich flanking region, C-terminal domain, protein family |
| P361 | part of | ... | Q95352444 (Leucine-rich repeat, typical subtype, protein family) | Leucine-rich repeat, typical subtype, protein family |
| P129 | physically interacts with | ... | Q27088534 (resatorvid) | resatorvid |
| P279 | subclass of | ... | Q408004 (toll-like receptor) | toll-like receptor |
| P705 | Ensembl protein ID | ENSP00000363089 |
| P705 | Ensembl protein ID | ENSP00000377997 |
| P705 | Ensembl protein ID | ENSP00000496429 |
| P646 | Freebase ID | /m/02r7yg2 |
| P486 | MeSH descriptor ID | D051197 |
| P672 | MeSH tree code | D12.776.543.750.705.910.500.400 |
| P638 | PDB structure ID | 4G8A |
| P638 | PDB structure ID | 3UL8 |
| P638 | PDB structure ID | 3FXI |
| P638 | PDB structure ID | 3ULA |
| P638 | PDB structure ID | 3UL9 |
| P638 | PDB structure ID | 3UL7 |
| P638 | PDB structure ID | 2Z65 |
| P638 | PDB structure ID | 2Z62 |
| P638 | PDB structure ID | 2Z63 |
| P638 | PDB structure ID | 2Z66 |
| P637 | RefSeq protein ID | NP_003257 |
| P637 | RefSeq protein ID | NP_612564 |
| P637 | RefSeq protein ID | NP_612567 |
| P7260 | Transporter Classification Database ID | 8.A.43.1.9 |
| P2892 | UMLS CUI | C1411976 |
| P352 | UniProt protein ID | O00206 |
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