The role of nanotoxicology in realizing the 'helping without harm' paradigm of nanomedicine: lessons from studies of pulmonary effects of single-walled carbon nanotubes

journal article published in 2010

The role of nanotoxicology in realizing the 'helping without harm' paradigm of nanomedicine: lessons from studies of pulmonary effects of single-walled carbon nanotubes is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1111/J.1365-2796.2009.02188.X
P2880NIOSHTIC-2 ID20036242
P698PubMed publication ID20059647
P5875ResearchGate publication ID40897470

P50authorValerian E. KaganQ64855790
Anna A. ShvedovaQ64539049
P2860cites workMechanisms of pulmonary toxicity and medical applications of carbon nanotubes: two faces of Janus?Q23909384
Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesisQ23909387
Vitamin E deficiency enhances pulmonary inflammatory response and oxidative stress induced by single walled carbon nanotubes in C57BL/6 miceQ23909979
Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in miceQ23909986
Sequential exposure to carbon nanotubes and bacteria enhances pulmonary inflammation and infectivityQ23909989
Untitled - Letter to the editorQ23913013
Induction of aneuploidy by single-walled carbon nanotubesQ23916633
Phosphatidylserine targets single-walled carbon nanotubes to professional phagocytes in vitro and in vivoQ23918711
Alteration of deposition pattern and pulmonary response as a result of improved dispersion of aspirated single-walled carbon nanotubes in a mouse modelQ23919831
Direct and indirect effects of single walled carbon nanotubes on RAW 264.7 macrophages: role of ironQ23923113
Appetizing rancidity of apoptotic cells for macrophages: oxidation, externalization, and recognition of phosphatidylserineQ23923115
Nanotoxicology: an emerging discipline evolving from studies of ultrafine particlesQ24536032
Drug delivery and nanoparticles:applications and hazardsQ24655744
Aneuploidy: a report of an ECETOC task forceQ74547793
Apoptotic cells quench reactive oxygen and nitrogen species and modulate TNF-alpha/TGF-beta1 balance in activated macrophages: involvement of phosphatidylserine-dependent and -independent pathwaysQ81699209
Re: Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotubeQ81725257
Mechanisms of cardiolipin oxidation by cytochrome c: relevance to pro- and antiapoptotic functions of etoposideQ83323272
Nanoparticles: pharmacological and toxicological significanceQ24681563
Toxic potential of materials at the nanolevelQ28295314
Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot studyQ29547366
Respiratory toxicity of multi-wall carbon nanotubesQ29547367
Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillationQ29547369
Translocation of Inhaled Ultrafine Particles to the BrainQ29547870
Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigmQ29615517
Pulmonary and systemic immune response to inhaled multiwalled carbon nanotubesQ29615531
Inhaled multiwalled carbon nanotubes potentiate airway fibrosis in murine allergic asthmaQ29615715
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Redox imbalanceQ33206786
Viruses: making friends with old foesQ33243176
Thermal scalpel to target cancerQ33278525
Chrysotile effects on human lung cell carcinoma in culture: 3-D reconstruction and DNA quantification by image analysisQ33347595
Biodegradation of single-walled carbon nanotubes through enzymatic catalysisQ33379684
Functionalized carbon nanotubes are non-cytotoxic and preserve the functionality of primary immune cells.Q34546519
Pulmonary and systemic oxidant/antioxidant imbalance in chronic obstructive pulmonary diseaseQ34560278
Biodegradable luminescent porous silicon nanoparticles for in vivo applicationsQ34684415
Nanotechnology and health safety--toxicity and risk assessments of nanostructured materials on human health.Q34714424
Reactive oxygen species in pulmonary inflammation by ambient particulatesQ35192350
Phagocytosis induces superoxide formation and apoptosis in macrophagesQ35596821
Mechanisms of pulmonary fibrosisQ35640281
Centrosome amplification and the origin of chromosomal instability in breast cancerQ35959371
Reactive nitrogen species in the respiratory tractQ36389957
Towards the use of nanoparticles in cancer therapy and imagingQ36885448
Membrane redox state and apoptosis: death by peroxideQ37257839
Nanotechnology in medical imaging: probe design and applications.Q37341362
Effects of nanomaterial physicochemical properties on in vivo toxicity.Q37345372
Science and technology integration for increased human potential and societal outcomesQ40504031
A role for oxidative stress in apoptosis: oxidation and externalization of phosphatidylserine is required for macrophage clearance of cells undergoing Fas-mediated apoptosisQ40723230
Injectable gold compounds: an overviewQ41248894
Exposure to nanoparticles is related to pleural effusion, pulmonary fibrosis and granulomaQ43288620
Accelerated progression of asbestos-induced mesotheliomas in heterozygous p53+/- miceQ44085246
Enhanced oxidative stress in iNOS-deficient mice after traumatic brain injury: support for a neuroprotective role of iNOS.Q45270337
Pro-inflammatory and potential allergic responses resulting from B cell activation in mice treated with multi-walled carbon nanotubes by intratracheal instillation.Q46018240
Single-walled and multi-walled carbon nanotubes promote allergic immune responses in miceQ46085095
A pilot toxicology study of single-walled carbon nanotubes in a small sample of miceQ46119384
Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by four typical nanomaterials: the role of particle size, shape and compositionQ46404360
Pulmonary bioassay studies with nanoscale and fine-quartz particles in rats: toxicity is not dependent upon particle size but on surface characteristicsQ47318204
Absence of Carcinogenic Response to Multiwall Carbon Nanotubes in a 2-Year Bioassay in the Peritoneal Cavity of the RatQ56834605
P6195funding schemegrantQ230788
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectlungQ7886
nanotechnologyQ11468
manufacturingQ187939
cytotoxicityQ246181
respiratory diseaseQ3286546
response to stimulusQ14859560
nanomedicineQ261659
particulatesQ498957
carbon nanotubeQ1778729
nanotoxicologyQ2518429
P5008on focus list of Wikimedia projectWikimedia–NIOSH collaborationQ104416361
P304page(s)106-118
P12526performing organizationUniversity of PittsburghQ235034
P577publication date2010-01-01
P1433published inJournal of Internal MedicineQ6295387
P859sponsorNIOSH Health Effects Laboratory DivisionQ123344455
Comprehensive assessment of hazardous effects of engineered nanomaterials on the immune systemQ55095475
P1476titleThe role of nanotoxicology in realizing the 'helping without harm' paradigm of nanomedicine: lessons from studies of pulmonary effects of single-walled carbon nanotubes
P478volume267

Reverse relations

cites work (P2860)
Q46193681A single intratracheal instillation of single-walled carbon nanotubes induced early lung fibrosis and subchronic tissue damage in mice
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Q23909718Direct effects of carbon nanotubes on dendritic cells induce immune suppression upon pulmonary exposure
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